. Aldo Roda
Laboratory of Analytical & Bioanalytical Chemistry
Department of Chemistry G. Ciamician,
Alma Mater Studiorum - University of Bologna
Via Selmi 2, 40126 Bologna, Italy
Phone and Fax +39 051 343398
E-mail aldo.roda@unibo.it
Web http://www.anchem.unibo.it
Date of birth: 07/04/1949
Nationality: Italian
Current Position
- Full professor of Analytical Chemistry, “Giacomo Ciamician” Department of Chemistry, Alma Mater Studiorum - University of Bologna.
ACADEMIC CAREER
2021 Emeritus Professor, Alma Mater Studiorum University of Bologna
2019-2021 Alma Mater Honorary Professor, University of Bologna
1992-2019 Full professor of Analytical Chemistry, University of Bologna
1990-1992 Full professor of Medicinal Chemistry and Pharmaceutical Analysis, University of Bologna
1986-1990 Full professor of Analytical Chemistry, University of Messina
1980-1986 Researcher in Inorganic Chemistry and Analytical Clinical Chemistry, University of Bologna
1973-1980 Research Assistant, University of Bologna
1977 Postgraduate Ph.D. in Analytical Chemistry, University of Bologna: Magna Cum Laude
1973 DSc Degree in Chemistry, Laurea in Chimica, University of Bologna: (110/110 with laude).
AWARDS AND HONORS
2023- Medal “Giovanni Dugo, “ Interdivisional group of Sepation Sciences (GISS) SCI: Italial Chermical Society
2021- DAC-EuChemS Award (Division of Analytical Chemistry of the European Chemical Society
2019- Career Award of Analytical Chemistry Division SCI, Italian Chemical Society
2018 -Mangia Medal Award, Division of Analytical Chemistry, Bioanalytical Chemistry group, SCI: ItalianChemical Society
2017- Liberti medal of the Analytical and Environmental Chemistry division SCI: Italian Chemical Society
2005-present “Accademico Benedettino” and member of the “Consiglio Direttivo” of Accademia of Sciences, Institute of Bologna
2013- 2024 Vice President of INBB (National Institute of Biosystems and Biostrucures) Interuniversitary Consortium-
2013-2015 President of the "International Society for Bioluminescence and Chemiluminescence"(ISBC).
2010-2013 Vice President of the Società Chimica Italiana SCI
2003-2006 President of the Division of Analytical Chemistry, of the Italian Society Chemistry, SCI.
2000-2002 President of the International Society for Bioluminescence and Chemiluminescence (ISBC).
1986-1992 IUPAC delegate for Italy, Division of Clinical Chemistry
1984-1990 Member of the Advisory Board of the Italian Society of Clinical Chemistry (SIBIOC)
EDITORIAL POSITIONS
2018-present Associate Editor of Biosensors and Bioelectronics, Elsevier
2006-present Co-Editor in Chief of Luminescence -The Journal of Biological and Chemical Luminescence (Wiley & Sons)
1998-2018 Editor of ABC, Journal of Analytical and Bioanalytical Chemistry, Springer Nature
1994-1998 Member of the Editorial Board of Analytical and Bioanalytical Chemistry , Springer Nature
PRESENTATIONS AND INVITED PLENARY LECTURES
A.R. has given more than 700 oral presentations at International Conferences, Universities and Research Institutions in many Countries. Selected invited presentations and lectures are reported:
1. Exosomes and their cargo as “two in one” sensitive and predictive liquid biopsy tools for cancer biomarkers: new generation of luminescence-based biosensors integrated with fff isolation from biological fluids, Biosensors, X International workshop, 13-15 October 2022, Dakhla , Morocco
2. Current status and perspectives of miniaturized portable luminescence-based biosensors, 21st ISBC & 19th ISLS Symposium, 31 May-3June 2022 Gijon, Spain
3. Recent Advances and Challenges in bio-chemiluminescence based biosensors, 2021 DAC-EuChemS Lecturer Awardees, Webinair, 16 September 2021
4. Chemical Luminescence-based Smartphone Biosensor : A Simple Tool for Portable Diagnostics in Developing Countries PITTCON Conference March 1-5,2020
5. Nature inspired bioluminescence sensing, ASCOS 2019, 21-28 July 2019 Bertinoro Italy
6. Nature inspired bioluminescence : toward new generation cell-based and reagent-less biosensors , XXII Reunion de la Societad Espanola de Quimica Analitica, Valladolid, 17-19 July, 2019
7. Smartphone-based biosensors: Present status and perspectives, XX EuroAnalysis, Istanbul, 1-5 September 2019
8. Bioluminescent cell-based biosensors, SPIE- Optics+Optoelectronics, April,1-4, 2019 Praha
9. A portable chemiluminescence-based immunosensor to non-invasively monitor the health of astronauts during long-term space exploration: results from ASI/ESA/NASA “VITA” mission on board of the International Space Station (ISS), Biosensors 2018 World Congress on Biosensors, 12-15 June 2018, Miami USA
10. A new class of Pdot CN-PPV and ORMOSIL nanoparticles doped with thermochemiluminescent 1,2-Dioxetane derivatives: Comparative study for sensitive biosensor applications, The 2nd Middle-Eastern Material, New York University Abu Dhabi, United Arab Emirates, November 12-14, 201
11. A portable chemiluminescence-based immunosensor to non-invasively monitor the health of astronauts during long-term space exploration: Results from ASI/ESA/NASA “VITA” mission on board of the International Space Station (ISS), EuroOpt(r)ode XIV , Naples, 25-28 March, 2018
12. Advanced instrumentation for the astronaut health monitoring and diagnostics during long-term space exploration, XXVI Congresso Nazionale della Società Chimica Italiana Italiana, Paestum (SA) 10-14 settembre 2017
13. The use of smartphone as analytical portable device: update and critical review, ICAS 2017 International Congress on Analytical Sciences, Hainan, China May 5-8 2017
14. Effect–based fourplex cell bioluminescent biosensors battery for food and aquatic environment safety assessment: 8th International Workshop on Biosensors, 12-14 oct 2017 , Rabat , Morocco
15. Bile acids structure-physicochemical properties, and molecular cross talk between hepatic and intestinal metabolism, Bile Acids in the Small Intestine and Colon: Physiology, Pathophysiology, and Therapeutic, Hodgkin Huxley House, London November 17th - 18th 2016
16. Smartphone-based chemical luminescence 3d-printed biosensors for point-of-need applications , 7th International workshop on Biosensors , Erfoud, Morocco 19-21 Nov 20
17. Sostanze naturali e alimenti funzionali , Accademia delle Scienze di Bologna, 14 Ottobre 2015
18. Highlights in chemical luminescence-based biosensors and miniaturized devices, University of Science and Technology , Hafei China, June 12th,20
19. Principi e applicazioni della bio-chemiluminescenzai n campo biomedico, ambientale e tossicologico, Università di Catania, 21 gennaio 2014
20. Towards the three rs rules: reduction, replacement and refinement alternatives to animal experiments for drug discovery using bioluminescence cell-based and in vivo imaging approaches , PBA 2013, 30 June-3 July, Bologna
21. Multiplexing luminescent biosensors by chemical, electrochemical and thermal signal triggering. 10 Years Journal ABC: Outstanding Achievements in Analytical and Bioanalytical Chemistry Analytica 2012, Munich
22. Chemiluminescent-based biosensors for point-of-care multiplex sensing as a companion diagnostics in personalized medicine, Advances in Biodetection and Biosensors, 28-29 March 2012 Edinburgh Scotland
23. Bio-chemiluminescence-based analytical tools for ultrasensitive in vitro and in vivo drug screening 10th International Symposium on Pharmaceutical Sciences, June 26-29, 2012 Ankara, Turkey
24. Chemiluminescent-based biosensors for point-of-care testing and as a companion diagnostics in personalized medicine University of Sciences and Technology Liaoning Shengyang China November 1st, 2011
25. Bio-chemiluminescence-based biosensors for point-of-care applications
Biophotonics 2011, June8-10, 2011, Parma, Italy
26. New tools and new challenges in bioluminescence molecular imaging
16th International Symposium ISBC, Lyon, 2010
27. A new gastric-emptying mouse model based on in vivo non-invasive bioluminescence functional imaging
Digestive Disease Week, May 1-5, 2010 New Orleans, USA
28. Bioluminescent-based biosensors Europt(r)ode, March 28-31, 2010 Prague
29. Development of multiplexed non-invasive tests for the real-time monitoring of biomarkers of health status during the Mars500 human mission simulation , Accademy of Sciences, February 5th ,2009 Bologna
30. Breath Test: Sistema non invasivo per la determinazione della motilità gastro-intestinale nel volo spaziale, IFC Pisa,Dec 19 2008
31. Biospecific recognition-assisted soft impact mass spectrometry for biomarker discovery, RDPA, 2007
32. Molecular Imaging Using Luminescent Probes JABC Japan Association for Bioluminescence and Chemiluminescence Okayama, 2005
33. Bioluminescent biosensors based on genetically engineered living cells in environmental and food analysis, 2nd International Workshop on : "Biosensors for Food Safety and Environmental Monitoring" Agadir, November 10-12, 2005
34. Novel BRET-based biosensors with a new bioluminescent donor, Gaussia luciferase, for estrogen and androgen receptor ligands. 14th International Symposium on Bioluminescence & Chemiluminescence, Yokohama (Japan), 15-19 October 2006
35. Quantitative immunohistochemistry and in situ hybridization imaging procedures with luminescence detection: a new potential diagnostic tool. XII International Symposium on Luminescence Spectrometry. Detection Techniques in Biomedical, Environmental and Food Analysis, Lugo (Spain), 18 – 21 July 2006
36. Bioluminescence resonance energy transfer (BRET) nanotechnology: a tool for protein intercation studies. XII International Symposium on Luminescence Spectrometry. Detection Techniques in Biomedical, Environmental and Food Analysis, Lugo (Spain), 18 – 21 July 2006.
37. Molecular bio-chemiluminescence imaging. XII Hungarian-Italian Symposium on Spectrochemistry: Environmental Pollution and Human Health, Pécs (Hungary), 23–27 October 2005.
38. Analytical proteomics using soft impact mass spectrometry. XII Hungarian-Italian Symposium on Spectrochemistry: Environmental Pollution and Human Health, Pécs (Hungary), 23–27 October 2005.
39. Luminescent probes for sensitive and specific optical microscope imaging. 13th International Symposium on Bioluminescence & Chemiluminescence, Yokohama (Japan), 2-6 August 2004.
40. A novel lanthanide chelate tag for ultrasensitive time-resolved fluorescence microscopy imaging of tissues and cells. 32nd Annual Meeting of the American Society for Photobiology, Seattle (USA), 10-14 July 2004.
41. Analytical Luminescence, Connecticut College, New London, USA, 9 July 2004
42. A novel microtiter plate format for single-well simultaneous multi-analyte chemiluminescent detection: application for the development of a PCR assay for typing human papilloma virus DNA. 12th International Symposium on Bioluminescence and Chemiluminescence, Cambridge (UK), 5-9 April 2002
43. Novel strategies for the sampling and screening of dredged contaminated sediments, NSF Wasihington DC, December 15, 2002
44. Ultrasensitive luminescence microscope imaging in biosciences, CNRS Strasbourg, France 2002
45. Analytical Bio-Chemiluminescence Limoges, France 2001
46. Bile acids Metabolism and Pharmacological activity, Nicox, Sophia Antipolis, Nice, France 2001
47. The Innovation in micotoxin analytical tests. X International Symposium of World association of Veterinary Laboratory Diagnosticians, Parma, 5 Luglio 2001
48. Development of a time-resolved fluorescence microscope for imaging analysis. 11th International Symposium on Bioluminescence and Chemiluminescence, Asilomar, CA, September 6-10, 2000
49. Analytical performance and applications of microscope-low light imaging using chemiluminescence and time-resolved fluorescence: immunohistochemical and in situ hybridization reactions. IX International Symposium on Luminescence Spectrometry, Montpellier, 15-17 May 2000
50. Bile acid structure activity relationship, Mayo Clinic, Rochester MN, USA, 5 May 2000
51. Modified bile acids. 3rd International Conference on Gallstones, Tiberias (Israel), 10-14 October 1999
52. Breath testing: a non invasive tool for the gastroenterologist. IIIrd International Workshop on Chronic Infections in Gastrointestinal Diseases, Rome, 1-2 July 1999.
53. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid induced cholestasis in rat. XV International Bile Acid Meeting: Bile Acids and Cholestasis, Titisee (Germany), October 12-13, 1998.
54. Bio- and chemiluminescence imaging in bioanalysis. Drug Analysis ’98, Brussels, Belgium, May 11-15, 1998.
55. Detection of biospecific reactions by chemiluminescent imaging. Symposium on Medical Biotechnology. Szeged, Hungary, March 29-31, 1998.
56. Ultrasensitive bio- and chemiluminescent imaging using an optical microscope-videocamera luminograph: applications in biosciences and drug screening. Luminescence Assays for Industry, Cambridge, UK, September 22-23, 1997.
57. Quantitative high performance low-light imaging in biosciences. Institute of Hydrochemistry, Technical University of Munich, 14th April 1997.
58. Quantitative high performance low-light imaging in biosciences. Euroanalysis IX, Bologna, September 1-7, 1996
59. Chemiluminescence imaging as a bioanalytical tool. J Biolumin Chemilumin, 11, 264, 1996. 9th International Symposium on Bioluminescence and Chemiluminescence, Woods Hole, October 4-8, 1996.
60. Antioxidants properties of Bile Acids, Internation Symposium on Gastroenterology San Paolo Brasil, 1996
61. HPLC-electrospray-mass spectrometry of the artificial sweetener aspartame and use of a post-column photochemical reactor. 33rd International Congress on Foernsic & 1st on environmental toxicology (gretox 1995), August 27-31 1995, Thessaloniki, Greece.
62. Use of termostable luminescent bacteria as a rapid cytotoxicity test. 8th International Symposium on Bioluminescence and Chemiluminescence, Cambridge, UK, September 5-8, 1994
63. Improved intestinal absorption of an enteric-coated sodium ursodeoxycholate formulation. XIII International Bile Acid Meeting - Bile Acids in Gastroenterology: Basic and Clinical Advances, San Diego (USA), 30 settembre-2 ottobre 1994.
64. Analytical performance of a new highly sensitive luminometer. VIIth International Symposium on Bioluminescence and Chemiluminescence, Banff, Alberta, Canada, March 14-18, 1993.
65. SAR on Bile Acids, NIH, Warrenton, Virginia Airlie House USA April 1989
66. Relationship between physicochemical and biological properties of bile acids in solution. 32nd IUPAC Congress, Stockolm, Sweden, August 27, 1989
67. Physicochemical and Physiological properties of New bile acids analogues, Advances in Bile acids Therapy, Vail Colorado USA August 26-27,1988
68. Recent acquisitions on serum bile acids: methods development and clinical applications, Institut J.Curie, Budapest Hungry, 1985
69. Recent acquisitions on the Chemistry and Physiology of bile acids , Cinese National academy of Science, Beijin China, 1982
70. Physical-Chemistry of bile salt solutions, University of New Dehly, India, 1982
71. Recent Acquisition on the analysis of bile acids by HPLC, workshop on HPLC: application in Biology ann Pathology, Locarno Switzerland, 1982
RESEARCH ACTIVITY
The main activity focuses on both basic and applied bio-analytical chemistry from the development and validation of sensitive miniaturized bioassay, immunoassay, biosensors, lateral flow and paper-based POCT and (microscope) imaging based on bio-chemiluminescence, electrogenerated luminescence thermochemiluminescence, colorimetric and reflectance principle . Analytical mass-spectrometry using different instrumentation from MALDI, HPLC-ESMS/MS, QTOF is part of his scientific activity. Bile acids has been a basic research acrivity since 1975 focusing on Physical-chemistry, Analytical Chemistry, Physiopathology, Pharmacology and Medicinal Chemistry of new semisynthetic analogues active in hepatogratroenterology disease.
PUBLICATIONS
AR published up to 500 original articles and 10 edited books on international journals with high IF. He has and an Hirsch index, Scopus : H=66 and over 17,221 citations. o ORCID:0000-0001-7649-4797,
o Google scholar: https://scholar.google.it/citations?hl=it&pli=1&user=A9I5eWMAAAAJ
TEACHING ACTIVITY
Courses held in the University of Bologna
o Regularly taught lecture courses every year since 1982, mainly in:
o Analytical Chemistry and Laboratory including stoichiometry in the Faculty of Pharmacy and Biotechnology;
o Instrumental Analytical Chemistry in Chemistry courses and the post-graduated courses;
o Biosensors and Nano-analytics and High-throughput screening in post graduated course of Biotechnology and Bioinformatics;
o Bioanalytical Chemistry and laboratory in the Biotechnology courses.
o Analytical Chemistry in the Doctorate of Chemistry.
Supervising Activity
Over 150 “Tesi di Laurea” (1 year master-like thesis) supervised (“Relatore”) at University of Bologna
25 PhD Thesis supervised (“Relatore”) at University of Bologna
Has supervised over 15 international predoctoral and postdoctoral fellows from different European Countries
ORGANIZATION OF SCHOOLS, WORKSHOPS, CONFERENCES
A.R. during his career organizes up to 50 scientific national and international events.
Selected Scientific events
o President of the XXVII Congress of the Divison of Analytical Chemistry, Società Chimica Italiana, Bologna September 17-20, 2018
o Member of the Scientific commttee of the 19th International Symposium on Bioluminescence and Chemiluminescence, May 29-June 2,2016, Tsukuba, Japan
o President of the XII International Symposium on Luminescence Spectrometry ISLS - Detection Techniques in Biomedical, Environmental and
Food Analysis, Bologna September 7-11, 2000
o Co-chairman of the Analytical Chemistry sessions of the 41th IUPAC World Chemistry Congress, Turin, August 5-11, 2007
o President of the 10th ISBC, Bologna September 4-8, 1998
o Member of the organizing committee of EUROANALYSIS IX, September 1-7, 1996
MANAGING ACTIVITIES AT NATIONAL AND INTERNATIONAL LEVEL (selected)
o Member of the Euro Bachelor evaluation: evaluation of university facilities, teaching program, credit and logistic
o 2010- present. Scientific collaboration with the IBMP: Institute of Biomedical Problems (Moscow, Russia) regarding the international project: Mars500
o 1999: Galileo Project: bilateral scientific exchange between Italy and France: collaboration with the CNRS of Strasbourg, France
THIRD MISSION
A.R. founded two Academic Spin-off:
o RDPharmAdvice Srl for the development of Diagnostics new drugs, nutraceutics and theragnostics. Owner of an EU patent for the use of nanoparticles as a label free sensitive detection.
o Lumina nanobiotec included in the Cube lab, which is an academic spinoff focused on the development of biotech products capable of performing tests outside the testing laboratory.
Patent co-inventorship
A.R. is coauthor of up to 35 national and international patents on new drugs, biosensors, sensing materials, analytical bioluminescence and chemiluminescence, nanoparticles:
1)Roda A., Di Fusco M., Quintavalla A., Guardigli M., Mirasoli M., Lombardo M., Trombini C.: Method for the production of thermochemiluminescent silica nanoparticles and their use as markers in bioanalytic methods, Massimo Di Fuesco Massimo Guardigli,Marco Lombardo,m Mara Mirasoli, Arianna Quintavalla, Aldo Roda, Claudio Trombini, EP2883055B1, 2013
2)Branchini B.R., Southworth T.L., De Angelis J., Michelini E., Roda A.: Isolated luciferase gene of L. italica, US102816-100, 2006.
3)Charbonniere L., Ziessel R., Wiebel N., Roda A., Guardigli M.: Lanthanide bis(carboxybipyridylmethyl)aminoalkanedicarboxylate complexes and analogs, their preparation and their uses as fluorescence markers and T.L., De Angelis J., Michelini E., Roda A.: Isolated luciferase gene of L. italica, US102816-100, 2006.
4) Charbonniere L., Ziessel R., Wiebel N., Roda A., Guardigli M.: Lanthanide bis(carboxybipyridylmethyl)aminoalkanedicarboxylate complexes and analogs, their preparation and their uses as fluorescence markers and NMR relaxation agents, WO2005/014581, 2005.
5) Crespi Petrellino N., Danieli B., Roda A., Bondi M., Marchioretto I.D., Minghetti A.: Compounds with an antioxidant acitivity, compositions useful as food integrators containing them and process for their preparation (Giuliani SpA, IT), ITMI20000066, 2001.
6) Rodriguez L., Passerini N., Roda A.: Procedimento per l'intima associazione di preparazioni attive di un vettore solido, apparecchiatura che realizza tale metodo e prodotti così ottenuti (Ascor Chimici srl, IT), IT1306015, 2001.
7) Roda A., Paolini M.: Acidi biliari come induttori del sistema citocromo p450-dipendente, in particolare ad attivita' anticolestatica, IT1299270, 2000.
8) Berlati, Fabio; Ceschel, Giancarlo; Roda, Aldo; Roda, Enrico; Ronchi, Celestino; Nor- and homo- bile acids derivatives as absorption enhancers for medicaments US 5656277
9) Pellicciari R., Roda A.: Bile acid unsaturated derivatives processes for the preparation thereof and pharmaceutical compositions containing them (Giuliani SpA, IT), HK1006313, 1999.
10) Lorenzo L., Roda A.: Procedimento per l'intima associazione di preparazioni attive a un vettore solido, apparecchiatura che realizza tale metodo e prodotti cosi' ottenuti (Giuliani SpA, IT), ITBO980236, 1999.
11)Cainelli G., Milani M.R., Marchi E., Piani S., A. Roda: Bile acids derivatives useful in the therapy of the biliary calculosis from cholesterol and of the pathologies caused by cholestasis (Alfa Wassermann SpA, IT), GR3025811T, 1998.
12)Roda A., Bonaldi A., Molinari E.: Process for the preparation of glycine-conjugated bile acids and relative pharmaceutical compositions useful for treating hepatic insufficiency (Erregierre Ind. Chim., IT), DE69321177D, 1998.
13)Ceschel G., Berlati F., Roda A., Roda E., Ronchi C.: Nor- and homo- bile acids derivatives as absorption enhancers for medicaments (Monteresearch srl, IT), DK652773T, 1998.
14)Roda A., Bonaldi A., Molinari E.: Verfahren zur herstellung glycin-konjugierter gallensäure (Erregierre Ind. Chim., IT), AT171458T, 1998.
15)Berlati F., Ceschel G., Roda A., Roda E., Ronchi C.: Anwendung von nor- und homo-gallensäurederivaten als absorptienförderer für arzneimittel (Monteresearch srl, IT), AT161731T, 1998.
16)Marchi E., Milani M.R., Piani S., Roda A., Cainelli G.: Gallensäurederivate zur behandlung von gallenwegsteinen von cholesterin und davon verursauchte pathologien (Alfa Wassermann SpA, IT), AT160785T, 1997.
17)Frigerio G., Roda A., Roda E.: Pharmaceutical compositions for the treatment of hypercholesterolemiae (Chemical and Biolog. Ind. Limited, IE), ITMI952686, 1997.
18)Frigerio G., Roda A., Roda E.: Composizioni farmaceutiche per il trattamento delle ipercolesterolemie (Chemical and Biolog. Ind. Limited, IE), IT1277117, 1997.
19) Bonaldi A., Molinari E., Roda A.: Process for the preparation of glycine-conjugated bile acids (Erregierre Ind. Chim., IT), US5616741, 1997.
20) Frigerio G., Roda A., Roda E.: Composizioni farmaceutiche per il trattamento delle epatopatie croniche (Chemical and Biolog. Ind. Limited, IE), IT1277118, 1997.
21) Giuliano G., Aldo A., Roda E.: Pharmaceutical compositions for the treatment of chronic hepatoses (Chemical and Biolog. Ind. Limited, IE), ITMI952687, 1997.
22) Pellicciari R., Roda A., Frigerio G.: Gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus (Giuliani SpA SpA, IT), AT124953T, 1995.
23) Pellicciari R., Roda A., Frigerio G.: Fluorierte gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus (Giuliani SpA, IT), AT131173T, 1995.
24) Berlati F., Ceschel G., Clerici C., Pellicciari R., Roda A., Ronchi C.: The use of bile acids as antiviral agents (Montefarmaco SpA, IT), WO9400126, 1994.
25) Frigerio G., Roda A., Pellicciari R.: Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten (Istituto D. Giuliani SpA, IT), AT75750T, 1992.
26) Frigerio G., Roda A., Roda E.: Complex of products for the rapid and non-invasive treatment of biliary calculosis (Giuliani SpA, IT), DE3777559D, 1992.
27) Frigerio G., Roda A., Pellicciari R.: Billiary acid derivatives, processes for the preparation thereof and phamaceutical compositions containing them (Gipharmex SpA, IT), DE3870801D, 1992.
28) Frigerio G., Roda A., Roda E.: Produktekomplex fuer die schnelle und nicht eindringende behandlung von gallensteinen (Giuliani SpA, IT), AT73661T, 1992.
29) Pellicciari R., Roda A., Frigerio G.: Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them (Giuliani SpA, IT), US5175320, 1992.
30) Pellicciari R., Roda A., Frigerio G.: Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them (Giuliani SpA, IT), US5166374, 1992.
31) Frigerio G., Pellicciari R., Roda A.: Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them (Giuliani SpA, IT), IT1229570, 1991.
32) Frigerio G., Pellicciari R., Roda A.: Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them (Giuliani SpA, IT), IT1229569, 1991.
33) Castagnola V., Frigerio G., Pellicciari R., Roda A.: Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten (Gipharmex SpA, IT1199, AT50583T, 1990.
34) Castagnola V., Frigerio G., Pellicciari R., Roda A.: Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions (Gipharmex SpA, IT), DE3481419D, 1990.
35) V. Castagnola, G. Frigerio, R. Pellicciari, A. Roda: Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions (Gipharmex SpA, IT), US4892868, 1990.
36) Frigerio G., Roda A, Roda E. : Complesso di prodotti per il trattamento rapido e non invasivo della calcolosi biliare, IT1199843B, 1986
National Public Research Funding (selected, last ten years)
- 2016 Bando Regione Emilia Romagna Por Fesr per progetti di ricerca industriale strategica rivolti agli ambiti prioritari della Strategia di Specializzazione Intelligente: “Valorizzazione sostenibile degli scarti della filiera vitivinicola per l’industria chimica e salutistica (VALSOVIT)”.
- 2009 Bando Regione Emilia Romagna “Dai distretti produttivi ai distretti tecnologici”: “Functional Foods and Global Health” (Associated Investigator).
- 2009 PRIN: “Integration of biosensing and nanotechnology for medical diagnostics with high analytical performance” (Principal Investigator).
- 2009 ASI (Italian Space Agency): “Genomics, Proteomics and Metabolomics of the adaptive response to microgravity and magnetic fields” (Associated Investigator).
- 2008 ASI (Italian Space Agency): “Real time monitoring of health status during MARS 500 human mission simulation” (Coordinatore Nazionale).
- 2007 PRIN: “Integrated analytical devices for rapid, on-site analyses (POCT: Point of Care Testing) in critical medicine” (Principal Investigator).
- 2005 COFIN: “Bioanalytical miniaturized multiplexed methods” (Associated Investigator).
International research funding (selected, last ten years)
- 2016 NATO Science for Peace and Security (SPS) Programme: "Cell biosensors for detection of chemical and biological threats”.
- 2014 EU FP7 Capacities: “BIOtechnology for the recovery of valuable peptides from industrial RICE by-products and production of added value ingredients for nutraceuticals, functional foods and cosmetics (BIORICE)”.
- 2014 NASA - ESA (European Space Agency): “ISS Non-invasive Sample Investigation and results Transmission to ground with the Utmost easiness (IN SITU)” (Principal Investigator”.
- 2014 ASI (Italian Space Agency): “Modelli cellulari e tissutali bioluminescenti on ground e analisi proteomica funzionale per l’identificazione di target e pathways molecolari coinvolti nella motilità del sistema nervoso enterico in condizioni di microgravità (GUTBRAIN)” (Principal Investigator).
- 2011 Bill & Melinda Gates Foundation: “Gametocyte Assay for Malaria (GAM) for Novel Anti-Transmission Drugs” (Associated Investigator).
- 2010 IBMP (Institute for Biomedical Problems, Moscow, Russia): “Development of diagnostic methods based on portable devices for investigating the motility, functionalities, ecology and state of inflammation of the gastrointestinal systems of the crew members during the Mars500 isolation experiment” (Principal Investigator).
- 2008 ASI (Italian Space Agency): “Real time monitoring of health status during MARS 500 human mission simulation” (Principal Investigator).
International collaborations (recent)
- (2010 - ) Institute of Biomedical Problems, Moscow, Russia.
- (2004 - ) Connecticut College, New London, CT, USA.
