Foto del docente

Vincenzo Tumiatti

Full Professor

Department for Life Quality Studies

Academic discipline: CHIM/08 Pharmaceutical Chemistry

Director of Single Cycle Degree in Pharmacy

Publications

Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C., MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond, «CURRENT PHARMACEUTICAL DESIGN», 2009, 15, pp. 601 - 613 [Scientific article]

M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease, in: , «DRUGS OF THE FUTURE», 2009, 34, pp. 195 - 195 (atti di: Frontiers in medicinal chemistry: Emerging targets, novel candidates and innovative strategies, Barcelona, October, 4-6, 2009) [Abstract]

A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre, Polymethylene tetraamine backbone as template for the development of biologically active polyamines, in: Biogenic amines: biochemical, physiological and clinical aspects, s.l, s.n, 2009, pp. 14 - 14 (atti di: Biogenic amines: biochemical, physiological and clinical aspects, Bertinoro (FC, Italy), 11-14, 2009) [Abstract]

Tumiatti V., A rational design of new multi-target-directed-ligands for the treatment of Alzheimer's disease, in: Mainzer Forums Medizinische Chemie, s.l, s.n, 2008, pp. 35 - 36 (atti di: 16th Mainzer Forum Medicinal Chemistry. Treatment strategies for dementia- a challenge of the 21st century, Mainz University (Germany), September 26th, 2008) [Contribution to conference proceedings]

A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosini; C. Melchiorre, Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 7311 - 7320 [Scientific article]

M. L. Bolognesi; A. Minarini; M. Rosini; V. Tumiatti; C. Melchiorre, From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease, «MINI-REVIEWS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 960 - 967 [Scientific article]

M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Tarozzi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 4381 - 4384 [Scientific article]

A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre, Multi-target-Directed Ligands To Combat Neurodegenerative Diseases, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 347 - 372 [Scientific article]

Gasperi-Campani A.; Baiocchi D.; Roncuzzi L.; Gilli E.; Milelli A.; Tumiatti V., NEWLY SYNTHESIZED POLYAMINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS, in: , «EUROPEAN JOURNAL OF CANCER», 2008, 6 (9), pp. 88 - 88 (atti di: 20th meeting of the European Association for Cancer Research, Lyon, France, 5-8. 07. 2008) [Abstract]

V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre, Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update, «EXPERT OPINION ON THERAPEUTIC PATENTS», 2008, 18, pp. 387 - 401 [Scientific article]

V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre, Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer., «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 7308 - 7312 [Scientific article]

V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre, Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone, in: Atti del XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, s.l, s.n, 2008, pp. 207 - 207 (atti di: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, Palermo, 18-21 Maggio 2008) [Abstract]

Melchiorre C.; Antonello A.; Banzi R.; Bolognesi M.L.; Minarini A.; Rosini M.; Tumiatti V., Polymethylene tetraamine backbone as template for the development of biologically active polyamines, «MEDICINAL RESEARCH REVIEWS», 2003, 23, pp. 200 - 233 [Scientific article]

Rosini M.; Bixel M.G.; Marucci G.; Budriesi R.; Krauss M.; Bolognesi M.L.; Minarini A.; Tumiatti V.; Hucho F.; Melchiorre C., Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms, «JOURNAL OF MEDICINAL CHEMISTRY», 2002, 45, pp. 1860 - 1878 [Scientific article]

Bolognesi M.L.; Bixel M.G.; Marucci G.; Bartolini M.; Krauss M.; Angeli P.; Antonello A.; Rosini M.; Tumiatti V.; Hucho F.; Melchiorre C., Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure, «JOURNAL OF MEDICINAL CHEMISTRY», 2002, 45, pp. 3286 - 3295 [Scientific article]