F Castagnetti; G Rosti; M Breccia; F Stagno; A Gozzini; G Specchia; A Capucci; B Martino; G Rege Cambrin; L Luciano; E Abruzzese; M Bocchia; F Cavazzini; M Tiribelli; I Pierri; G Gugliotta; F Palandri; S Durante; S Soverini; N Testoni; F Pane; G Saglio; G Alimena; G Martinelli; M Baccarani, Frontline Treatment of Philadelphia Positive Chronic Myeloid Leukemia with Sequential Administration of Nilotinib 400 Mg Twice Daily and Imatinib 400 Mg Once Daily: a Phase 2 Multicentric Study, in: s1, «HAEMATOLOGICA», 2012, 97, pp. 238 - 238 (atti di: 17th Congress of the European Hematology Association, Amsterdam, The Netherlands, June 14 – 17, 2012) [Abstract]
V Guadagnuolo; C Papayannidis; I Iacobucci; S Durante; C Terragna; E Ottaviani; F Cattina; M Abbenante; S Soverini; L Toni; W Levin; R Courtney; C Baldazzi; A Curti; M Baccarani; C Jamieson; J Cortes; V Oehler; K McLachlan; T Van Arsdale; G Martinelli, GAS1 AND KIF27 GENES ARE STRONGLY UP-REGULATED BIOMARKERS OF HEDGEHOG INHIBITION (PF-04449913) ON LEUKEMIA STEM CELLS IN PHASE I ACUTE MYELOID LEUKEMIA AND CHRONIC MYELOID LEUKEMIA TREATED PATIENTS, in: s1, «HAEMATOLOGICA», 2012, 97, pp. 438 - 438 (atti di: 17th Congress of the European Hematology Association, Amsterdam, The Netherlands, June 14 – 17, 2012) [Abstract]
Viviana Guadagnuolo; Cristina Papayannidis; Ilaria Iacobucci; Sandra Durante; Carolina Terragna; Emanuela Ottaviani; Maria Chiara Abbenante; Federica Cattina; Simona Soverini; Barbara Lama; Lucia Toni; Wendy Levin; Rachel Courtney; Carmen Baldazzi; Antonio Curti; Michele Baccarani; Catriona Jamieson; Jorge Cortes; Vivian Oehler; Karen McLachlan; Todd VanArsdale; Giovanni Martinelli, Gas1 and Kif27 genes are strongly up-regulated biomarkers of Hedgehog inhibition (PF-04449913) on leukemia stem cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia treated patients, in: Suppl. 1, Chicago, «CANCER RESEARCH», 2012, 72, pp. 1 - 1 (atti di: AACR 2012 Annual Meeting, Chicago, 30 March - 04 April 2012) [Abstract]
Soverini S.; De Benedittis C.; Castagnetti F.; Papayannidis C.;Gugliotta G.; Iacobucci I.; Venturi C.; Bochicchio MT.; Cattina F.; Russo D.; Rosti G.; Baccarani M.; Martinelli G., High Sensitivity Mutation Monitoring and Clonal Analysis by Ultra-Deep Amplicon Sequencing Uncover the Complexity of BCR-ABL Mutation Status in Philadelphia+ Patients Treated with Tyrosine Kinase Inhibitors, in: XII Congress of the Italian Society of Experimental Hematology, «HAEMATOLOGICA», 2012, 97(s2), pp. 17 - 17 (atti di: 12^ Congresso Nazionale SIES, Roma, 17-19 Ottobre 2012) [Abstract]
S Soverini; C De Benedittis; F Cattina; A Broucková; K Machová Poláková; D Russo; A Gnani; I Iacobucci; MT Bochicchio; F Castagnetti; G Gugliotta; F Palandri; C Papayannidis; H Klamová; A Vitale; M Vignetti; R Foà; G Rosti; M Baccarani; G Martinelli, High Sensitivity Mutation Screening and Clonal Analysis Allowed by Ultra-Deep Amplicon Sequencing Uncover the Complexity of Bcr-Abl Mutation Status in Patients Treated with Tyrosine Kinase Inhibitors, in: 17th Congress of the European Hematology Association, Amsterdam, The Netherlands, June 14–17, 2012, «HAEMATOLOGICA», 2012, 97(s1), pp. 453 - 453 (atti di: 17th Congress of the European Hematology Association, Amsterdam, The Netherlands, June 14 – 17, 2012) [Abstract]
Iacobucci I.; Iraci N.; Messina M.; Lonetti A.; Chiaretti S.; Valli E.; Ferrari A.; Papayannidis C.; Paoloni F.; Vitale A.; Storlazzi C.T.; Ottaviani E.; Guadagnuolo V.; Durante S.; Vignetti M.; Soverini S.; Pane F.; Foà R.; Baccarani M.; Müschen M.; Perini G.; Martinelli G., IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia., «PLOS ONE», 2012, 7, Article number: e40934 , pp. 1 - 10 [Scientific article]Open Access
Iacobucci I; Cattina F; Pomella S; Brighenti E; Papayannidis C; Derenzini E; Lonetti A; Ferrari A; Verga Falzacappa MV; Guadagnuolo V; Aluigi M; Ottaviani E; Abbenante MC; Soverini S; Russo D; Pelicci PG; Baccarani M; Martinelli G, Inhibition of DNA repair by the small molecule Chk1/Chk2 inhibitor PF-0477736 (Pfizer) in B-acute lymphoblastic leukemia (ALL), in: Proceedings: AACR 103rd Annual Meeting 2012, «CANCER RESEARCH», 2012, 72, pp. 1772 - 1772 (atti di: AACR 2012 Annual Meeting, Chicago, 30 March - 04 April 2012) [Abstract]
Branford S.; Kim D.W.; Soverini S.; Haque A.; Shou Y.; Woodman R.C.; Kantarjian H.M.; Martinelli G.; Radich J.P.; Saglio G.; Hochhaus A.; Hughes T.P.; Müller M.C., Initial Molecular Response at 3 Months May Predict Both Response and Event-Free Survival at 24 Months in Imatinib-Resistant or -Intolerant Patients With Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase Treated With Nilotinib, «JOURNAL OF CLINICAL ONCOLOGY», 2012, 30, pp. 4323 - 4329 [Scientific article]
D Russo; G Martinelli; M Malagola; V Cancelli; S Zedda; C Skert; S Soverini; I Iacobucci; D Turri; S Mirto; M Gobbi; I Pierri1; U Vitolo; P Pregno; M Fogli; N Testoni; A De vivo; F Castagnetti; E Morra; E Pungolino; F Di Raimondo; F Stagno; G Alimena; M Breccia; F Nobile; B Martino; A Rambaldi; T Intermesoli; G Saglio; G Rege Cambrin; G Visani; G Nicolini; P De Fabritiis; E Abruzzese; R Fanin; M Tiribelli ; P Galieni; C Bigazzi; G Specchia; E Angelucci; E Usala; C Musolino; S Ruso; L Gaidano; M Lunghi; F Lauria; M Bocchia; F Rodeghiero; A D’Emilio; A Bosi; V Santini; G Quarta; M Girasoli; G Fioritoni; R Di Lorenzo; B Cesana; G Rosti; M Baccarani., INTERMITTENT IMATINIB (INTERIM) TREATMENT IN PH+-CML ELDERLY PATIENTS IN STABLE COMPLETE CYTOGENETIC RESPONSE, in: s1, «HAEMATOLOGICA», 2012, 97, pp. 73 - 74 (atti di: 17th Congress of the European Hematology Association, Amsterdam, The Netherlands, June 14 – 17, 2012) [Abstract]
Iacobucci, Ilaria; Ferrari, Anna; Alexander, Kohlmann; Papayannidis, Cristina; Venturi, Claudia; Margherita, Perricone; Maria Chiara Fontana, ; Paola, Bresciani; Sabina, Chiaretti; Abbenante, Mariachiara; Paolini, Stefania; Parisi, Sarah; Cattina, Federica; Soverini, Simona; Domenico, Russo; Fabrizio, Pane; Robin, Foà; Mario, Luppi; Torsten, Haferlach; Baccarani, Michele; Martinelli, Giovanni, Loss of Heterozygosity At the C Wild-Type Allele of rs1042522 in the TP53 Gene Frequently Occurs During Progression of Adult BCR-ABL1 Positive Acute Lymphoblastic Leukemia (ALL), in: Blood, «BLOOD», 2012, 120(21), pp. 2497 - 2497 (atti di: 54th ASH Annual Meeting, Atlanta, GA, December 8 – 11, 2012) [Abstract]
Iacobucci I; Ferrari A; Lonetti A; Papayannidis C; Trino S; Venturi C; Ferrarini A; Venturini L; Abbenante MC; Parisi S; Cattina F; Soverini S; Russo D; Vignetti M; Pane F; Delledonne M; Baccarani M; Martinelli G., Molecular characterization of TP53 mutations in B-acute lymphoblastic leukemia (B-ALL) reveals missense substitutions, aberrant exon-junctions and intron retention events, in: s1, «HAEMATOLOGICA», 2012, 97, pp. 2 - 2 (atti di: 17th Congress of the European Hematology Association, Amsterdam, The Netherlands, June 14 – 17, 2012) [Abstract]
G Rosti; G Gugliotta; M Breccia; F Castagnetti; L Levato; A Capucci; M Tiribelli; A Zaccaria; M Bocchia; A Cuneo; F Stagno; G Specchia; M Musso; B Martino; M Cedrone; T Intermesoli; F Palandri; S Soverini; C Baldazzi; S Durante; N Testoni; G Alimena; F Pane; G Saglio; G Martinelli; M Baccarani, NILOTINIB 400 MG BID IN EARLY CHRONIC PHASE CHRONIC MYELOID LEUKEMIA: BEYOND 4 YEARS RESULTS REMAIN STABLE - THE GIMEMA CML WP TRIAL CML0307, in: s1, «HAEMATOLOGICA», 2012, 97, pp. 79 - 79 (atti di: 17th Congress of the European Hematology Association, Amsterdam, The Netherlands, June 14 – 17, 2012) [Abstract]
Papayannidis C; Guadagnuolo V; Iacobucci I; Durante S; Terragna C; Ottaviani E; Abbenante MC; Cattina F; Soverini S; Lama B; Toni L; Levin W; Courtney R; Baldazzi C; Curti A; Baccarani M; Jamieson C; Cortes J; Oehler V; McLachlan K; VanArsdale T; Martinelli G., PF-04449913 reverts multi drug resistance (MDR) by a strong down-regulation of ABCA2 and BCL2 on leukemia stem cells in phase I acute myeloid leukemia and chronic myeloid leukemia treated patients, in: Suppl. 1, «CANCER RESEARCH», 2012, 72, pp. 4619 - 4619 (atti di: AACR 2012 Annual Meeting, Chicago, 30 March - 04 April 2012) [Abstract]
Cristina Papayannidis, Mariachiara Abbenante, Sarah Parisi, Stefania Paolini, Ilaria Iacobucci, Federica Frabetti, Emanuela Ottaviani, Anna Ferrari, Viviana Guadagnuolo, Chiara Sartor, Simona Soverini, Caterina De Benedittis, Carmen Baldazzi, Nicoletta Testoni, Michele Baccarani, Giovanni Martinelli, PKC412 (Midostaurin) Is Safe and Highly Effective in Systemic Mastocytosis Patients: The Bologna Experience, «BLOOD», 2012, 120, pp. 1749 - 1749 [Abstract]
Soverini S; De Benedittis C; Gnani A; Iacobucci I; Castagnetti F; Gugliotta G; Papayannidis C; Cattina F; Russo D; Pantaleo MA; Rosti G; Baccarani M; Martinelli G, Resistance to second-line tyrosine kinase inhibitor treatment in imatinib-resistant Philadelphia-positive leukemia patients can be anticipated by ultra-deep sequencing of the BCR-ABL kinase domain using Roche 454 technology, in: Proceedings: AACR 103rd Annual Meeting 2012, Philadelphia, American Association of Cancer Research, «CANCER RESEARCH», 2012, 72, pp. 1884 - 1884 (atti di: AACR 2012 Annual Meeting, Chicago, 30 March - 04 April 2012) [Abstract]
