Foto del docente

Sanzio Candeletti

Assistant professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/14 Pharmacology

Curriculum vitae

1978. Degree (cum laude) in Pharmacy - University of Urbino.
1979-1980. Teacher in charge at the Course of Pharmacological Laboratory - University of Urbino.
1981. Laboratory Technical Director - Faculty of Pharmacy - University of Bologna.
1987. Visiting Scientist - Institute of Applied Neurophysiology -INRA - Paris (Director: Prof. D. Albe Fessard).
1998-2002. Temporary Professor of "Pharmacological assays" at the Degree Course of "Sanitary technician of biomedical laboratory" - Faculty of Medicine - University of Bologna.
2000-2002. Temporary Professor of "Applied Pharmacology" at the Degree Courses of Pharmacy and of Pharmaceutical Chemistry and Technology - Faculty of Pharmacy - University of Bologna.
2001. Researcher (permanent staff) - Faculty of Pharmacy - University of Bologna.
2002. Scientific Director of a Research Unit in the frame of the National Research Program PRIN 2002.
2003-2004. Temporary Professor of the following courses:"Applied Pharmacology", "Cellular and molecular pharmacology", "Neuropsychopharmacology" at the
Faculty of Pharmacy - University of Bologna.
2004. Scientific Director of a Research Unit in the frame of the National Research Program PRIN 2004.
2005-2007. Temporary Professor of the following courses: "Neuropsychopharmacology" "Applied Pharmacology", "General Pharmacology" at the Faculty of Pharmacy - University of Bologna.

2007. Scientific Director of a Research Unit in the frame of the National Research Program PRIN 2004.

2008. Temporary Professor of the following courses: "Neuropsychopharmacology" "Applied Pharmacology", "General Pharmacology" at the Faculty of Pharmacy - University of Bologna.

2009. Temporary Professor of the following courses: "Applied Pharmacology", "Pharmacognosy" (Rimini Campus), "General Pharmacology and Pharmacognosy" at the Faculty of Pharmacy - University of Bologna.


Sanzio Candeletti investigated the pharmacological, neurochemical and biological aspects of opioid and non opioid peptides, with particular reference to their involvement in the modulation of nociceptive transmission at different CNS levels, in the laboratory animal. He devoted his activity to the characterization of the pharmacodynamic profile of the classical opiopid neuropeptide dynorphin and of other neuropeptides such as nociceptin/orphanin FQ and the protein Bv8; he studied the alterations of neuropeptide levels and of their gene expression induced by pharmacological treatments, endocrine manipulations and pathological conditions. To this end, he utilized and improved microsurgery techniques for the central administration of peptides and the perfusion of the subachnoid space in laboratory
animals; employed different experimental models for the study of nociceptive transmission as well as receptor binding techniques, radioimmunological and molecular biology methodologies. He is author of more than 50 publications appeared in international journals.
He is member of National (SIF, SINS) and international (International Association for the Study of Pain) scientific societies.