Patrizia ROMUALDI, Ph.D.
Degree in Pharmacy in 1982.
Visiting Scientist at the Dept. of Pharmacology of the
Uniformed Services University of the Health Sciences di Bethesda,
MD, USA (1986-1987).
Ph.D. in Pharmaceutical Sciences (1989).
Researcher (Faculty of Pharmacy of the University of
Bologna)(since 1990).
Visiting Professor at the Dept. of Pharmacology of the
Uniformed Services University of the Health Sciences di Bethesda,
MD, USA (1992).
Visiting Scientist at the Biological Psychiatry Branch
del National Institute of Mental Health, Bethesda, MD, USA
(1992).
Assistant Professor of Applied Pharmacology of the
Faculty of Pharmacy of the University of Bologna (since
1994).
Guest Professor of Pharmacology at the Department of
Pharmacology of the Semmelweis University of Medicine of Budapest
(1995).
Associate Professor of Pharmacology of the University of
Bologna (2001).
Awarded with abilitation to Full Professor in 2017
She is member of the following Scientific Societies:
Italian Society of Pharmacology since 1984 (SIF)
Italian Society of Addictions since 1997
European Neuropeptide Club since 1989
Brain-Gut Society since 1988.
Interdept. Center for Biotechnologies (CIRB)
InterUniver. Center for Biotechnologies (CIB)
Research Projects:
Dr. Romualdi participates to several National Research Projects
on Pharmacology, Biotechnology and Neurosciences, granted by MIUR
(FIRB), Regione Emilia-Romagna and by CNR and also to
International Research Projects , granted by the NIH (National
Institute of Health) and NIDA (National Institute on Drug Abuse),
USA .
Collaborations:
She has currently collaborations with:
Dept. of Pharmacology of the Uniformed Services University of
the Health Sciences, Bethesda, MD, USA ;
Dept. of Pharmacology of the George Washington University,
Washington, DC, USA ;
The Biological Psychiatry Branch of the National Institute
of Mental Health, Bethesda, MD, USA;
The Department of Neurology, University of Miami School of
Medicine, Miami, FL
Dip. di Farmacologia dell'Università di Ferrara;
Dip. di Farmacologia dell'Università di Modena
And in the past with:
Dip. di Farmacologia dell'Università di Milano;
Università di Modena;
Dip. di Scienze Farmaceutiche dell'Università di Bologna,
Ferrara e Torino.
Prof .ssa Patrizia ROMUALDI
List of Pubblications
A)
Publications in extenso on International Journals and
Monographs
B) Short communications
C)
Meetings
1: Spampinato S, Candeletti S, Romualdi P, Russo A, Stanzani S, Ferri S. Effects of hypothalamic lesions on the content of dynorphin immunoreactivity in pituitary. Life Sci. 1983;33 Suppl 1:503-6. PubMed PMID: 6141497. IF 2,527.
2: Spampinato S, Candeletti S, Romualdi P, Speroni E, Cavicchini E, Spadaro C, Murari G, Giobbi G, Ferri S. Opioid receptors mediating the antinociceptive effect of dynorphin at spinal cord level. Ann Ist Super Sanita. 1984;20(1):99-102. PubMed PMID: 6152521. IF 0,941.
3: Spampinato S, Candeletti S, Cavicchini E, Romualdi P, Speroni E, Ferri S. Antinociceptive activity of salmon calcitonin injected intrathecally in the rat. Neurosci Lett. 1984 Mar 23;45(2):135-9. PubMed PMID: 6547217. IF 2,105.
4. CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPAMPINATO S., FERRI S., Antinociceptive activity of intrathecal opioid and non-opioid peptides ascertained by different analgesimetric procedures, Drugs Exptl.Clin.Res., 10, 877-882, 1984. IF 1.15
5: Candeletti S, Romualdi P, Spadaro C, Spampinato S, Ferri S. Studies on the antinociceptive effect of intrathecal salmon calcitonin. Peptides. 1985;6 Suppl 3:273-6. PubMed PMID: 3008120. IF 2,434
6: Spampinato S, Candeletti S, Romualdi P, Cavicchini E, Panerai AE, Ferri S. Possible involvement of dynorphinergic system in nociceptive transmission at spinal level. Neuropeptides. 1985 Feb;5(4-6):425-8. PubMed PMID: 2860601. IF 1,553
7: Ferri S, Cavicchini E, Romualdi P, Speroni E, Murari G. Possible mediation of catecholaminergic pathways in the antinociceptive effect of an extract of Cannabis sativa L. Psychopharmacology (Berl). 1986;89(2):244-7. PubMed PMID: 3088644. IF 4,077
8: Ferri S, Candeletti S, Cavicchini E, Romualdi P, Spampinato S, Speroni E. Investigations on dynorphin structurally-related opioid peptides. I. Impact on nociceptive transmission. II. Regulation of pituitary content. Ann Ist Super Sanita. 1988;24(3):397-402. PubMed PMID: 2903708. IF 0.941
9: Ferri S, Speroni E, Candeletti S, Cavicchini E, Romualdi P, Govoni P, Marchini M. Protection by opioids against gastric lesions caused by necrotizing agents. Pharmacology. 1988;36(2):140-4. PubMed PMID: 3353441. IF 1,788
10: Spampinato S, Ferri GL, Candeletti S, Romualdi P, Cavicchini E, Soimero L, Labò G, Ferri S. Regional distribution of immunoreactive dynorphin A in the human gastrointestinal tract. Neuropeptides. 1988 Apr;11(3):101-5. PubMed PMID2898739.IF 1,553
11: Spampinato S, Romualdi P, Candeletti S, Cavicchini E, Ferri S. Distinguishable effects of intrathecal dynorphins, somatostatin, neurotensin and s-calcitonin on nociception and motor function in the rat. Pain. 1988 Oct;35(1):95-104. PubMed PMID: 2904671. IF 5,777
12 ROMUALDI P., LESA G., FERRI S., An opiate chronic treatment affects prodynorphin gene expression. Pharmacol. Research, 21, 477-478, 1989. IF 4,436
13: Romualdi P, Rosenberger JG, Gozzini L, Cox BM. Vasoactive intestinal polypeptide carboxy-terminal fragment, VIP(22-28), and other fragments of VIP, in the central nervous system of the rat. Peptides. 1989 May-Jun;10(3):621-6. PubMed PMID: 2780421. IF 2,434
14: Romualdi P, Lesa G, Ferri S. Morphine affects prodynorphin gene expression in some areas of rat brain. Ann Ist Super Sanita. 1990;26(1):43-6. PubMed PMID: 2393216. IF 0,941
15: Romualdi P, Lesa G, Cox BM, Ferri S. Distribution and characterization of VIP-related peptides in the rat spinal cord. Neuropeptides. 1990 Aug;16(4):219-25. PubMed PMID: 2274116. IF 1,553
16: Romualdi P, Lesa G, Ferri S. The opioid antagonist naloxone influences prodynorphin gene expression. Pharmacol Res. 1990 ;22 (1):111-2. PubMed PMID: 2284224. IF 4,436
17: Pincelli C, Fantini F, Romualdi P, Lesa G, Giannetti A. Skin levels of vasoactive intestinal polypeptide in atopic dermatitis. Arch Dermatol Res. 1991;283(4):230-2. PubMed PMID: 1929540. IF 2,279
18 FANTINI F., PINCELLI C., ROMUALDI P., LESA G., SEIDENARI S., Cutaneous Vasoactive Intestinal Polypeptide levels in the elicitation phase of allergic contact dermatitis, Pharmacol. Skin, 4, 76-79, 1991. IF 2,910
19: Marastoni M, Salvadori S, Balboni G, Scaranari V, Santagada V, Romualdi P, Ferri S, Tomatis R. Studies on the anti-phospholipase A2 and anti-inflammatory activities of a synthetic nonapeptide from uteroglobin. Arzneimittelforschung. 1991 Mar;41(3):240-3. PubMed PMID: 1867659. IF 2,647
20: Romualdi P, Lesa G, Ferri S. Chronic opiate agonists down-regulate prodynorphin gene expression in rat brain. Brain Res. 1991 Nov 1;563(1-2):132-6. PubMed PMID: 1786525.IF 2,728
21: Pincelli C, Fantini F, Romualdi P, Sevignani C, Lesa G, Benassi L, Giannetti A. Substance P is diminished and vasoactive intestinal peptide is augmented in psoriatic lesions and these peptides exert disparate effects on the proliferation of cultured human keratinocytes. J Invest Dermatol. 1992 Apr;98(4):421-7. PubMed PMID: 1372339. IF 6,314
22: Fantini F, Pincelli C, Romualdi P, Donatini A, Giannetti A. Substance P levels are decreased in lesional skin of atopic dermatitis. Exp Dermatol. 1992 Oct;1(3):127-8. PubMed PMID: 1285408. IF 3,543
23: Romualdi P, Lesa G, Donatini A, Balboni G, Tomatis R, Ferri S. Alterations in vasoactive intestinal polypeptide-related peptides after pentylenetetrazole-induced seizures in rat brain. Eur J Pharmacol. 1992 Dec 15;229(2-3):149-53. PubMed PMID: 1490518. IF 2,516
24: Marastoni M, Scaranari V, Romualdi P, Donatini A, Ferri S, Tomatis R. Studies on the anti-phospholipase A2 and anti-inflammatory activities of a uteroglobin fragment and related peptides. Arzneimittelforschung. 1993 Sep;43(9):997-1000. PubMed PMID: 8240467.IF 2,647
25: Melchiorre C, Romualdi P, Bolognesi ML, Donatini A, Ferri S. Binding profile of benextramine at neuropeptide Y receptor subtypes in rat brain areas. Eur J Pharmacol. 1994 Nov 14;265(1-2):93-8. PubMed PMID: 7883034.IF 2,516
26: ROMUALDI P., DONATINI A., FERRI S., Opioid antagonists up-regulate prodynorphin gene expression in rat brain, Regul. Peptides, 47, 323-325, 1994IF 2,110
27: Romualdi P, Lesa G, Donatini A, Ferri S. Long-term exposure to opioid antagonists up-regulates prodynorphin gene expression in rat brain. Brain Res. 1995 Feb 20;672(1-2):42-7. PubMed PMID: 7749752. IF 2,516
28: Romualdi P, Donatini A, Bregola G, Bianchi C, Beani L, Ferri S, Simonato M. Early changes in prodynorphin mRNA and ir-dynorphin A levels after kindled seizures in the rat. Eur J Neurosci. 1995 Sep 1;7(9):1850-6. PubMed PMID: 8528458. IF 3,631
29 ROMUALDI P., DONATINI A., FERRI S., Prodynorphin gene expression regulation by chronic methamphetamine in rat brain, Analgesia, 1, 679-682, 1995 IF 3,286
30: Romualdi P, Donatini A, Izenwasser S, Cox BM, Ferri S. Chronic intracerebroventricular cocaine differentially affects prodynorphin gene expression in rat hypothalamus and caudate-putamen. Brain Res Mol Brain Res. 1996 Aug;40(1):153-6. PubMed PMID: 8840025.IF 2,728
31: Simonato M, Bregola G, Donatini A, Bianchi C, Beani L, Ferri S, Romualdi P. Kindled seizure-induced c-fos and prodynorphin mRNA expressions are unrelated in the rat brain. Eur J Neurosci. 1996 Oct;8(10):2064-7. PubMed PMID: 8921296.IF 3,631
32: Simonato M, Romualdi P. Dynorphin and epilepsy. Prog Neurobiol. 1996 Dec;50(5-6):557-83. Review. Erratum in: Prog Neurobiol 1997 Feb;51(2):223-4. PubMed PMID: 9015827. IF 8,874
33: Romualdi P, Donatini A, Capobianco A, Ferri S. Methamphetamine alters prodynorphin gene expression and dynorphin A levels in rat hypothalamus. Eur J Pharmacol. 1999 Jan 22;365(2-3):183-6. PubMed PMID: 9988101. IF 2,516
34: Bregola G, Candeletti S, Romualdi P, Simonato M. Limbic seizures increase pronociceptin mRNA levels in the thalamic reticular nucleus. Neuroreport. 1999 Feb 25;10(3):541-6. PubMed PMID: 10208586.IF 1,656
35: Candeletti S, Guerrini R, Calò G, Romualdi P, Ferri S. Supraspinal and spinal effects of [Phe1psi(CH2-NH)Gly2]-nociceptin(1-13)-NH2 on nociception in the rat. Life Sci. 2000;66(3):257-64. PubMed PMID: 10666001.IF 2,527
36: Romualdi P, Bregola G, Donatini A, Capobianco A, Simonato M. Region-specific changes in prodynorphin mRNA and ir-dynorphin A levels after kindled seizures. J Mol Neurosci. 1999 Aug-Oct;13(1-2):69-75. PubMed PMID: 10691294.IF, 2,504
37: Romualdi P, D'Addario C, Ferri S, Cox BM, Izenwasser S. Chronic GBR 12909 administration differentially alters prodynorphin gene expression compared to cocaine. Eur J Pharmacol. 2001 Feb 16;413(2-3):207-12. PubMed PMID: 11226394. IF 2,516
38: Sandrini M, Romualdi P, Vitale G, Morelli G, Capobianco A, Pini LA, Candeletti S. The effect of a paracetamol and morphine combination on dynorphin A levels in the rat brain. Biochem Pharmacol. 2001 Jun 1;61(11):1409-16. PubMed PMID: 11331077. IF 4,705
39: Sandrini M, Romualdi P, Capobianco A, Vitale G, Morelli G, Pini LA, Candeletti S. The effect of paracetamol on nociception and dynorphin A levels in the rat brain. Neuropeptides. 2001 Apr;35(2):110-6. PubMed PMID: 11384206.IF1,553
40: Collins S, D'Addario C, Romualdi P, Candeletti S, Izenwasser S. Regulation of dynorphin gene expression by kappa-opioid agonist treatment. Neuroreport. 2002 Jan 21;13(1):107-9. PubMed PMID: 11924869. IF 1,656
41: Romualdi P, Landuzzi D, D'Addario C, Candeletti S. Modulation of proorphaninFQ/N gene expression by morphine in the rat mesocorticolimbic system. Neuroreport. 2002 Apr 16;13(5):645-8. PubMed PMID: 11973463.IF 1,656
42: Bregola G, Zucchini S, Frigati L, Candeletti S, Romualdi P, Reinscheid R, Simonato M. Involvement of the neuropeptide orphanin FQ/nociceptin in kainate and kindling seizures and epileptogenesis. Epilepsia. 2002;43 Suppl 5:18-9. PubMed PMID: 12121289.IF 3,961
43: Bregola G, Zucchini S, Rodi D, Binaschi A, D'Addario C, Landuzzi D, Reinscheid R, Candeletti S, Romualdi P, Simonato M. Involvement of the neuropeptide nociceptin/orphanin FQ in kainate seizures. J Neurosci. 2002 Nov 15;22(22):10030-8. PubMed PMID: 12427860.IF 7,115
44: Di Benedetto M, D'Addario C, Collins S, Izenwasser S, Candeletti S, Romualdi P. Role of serotonin on cocaine-mediated effects on prodynorphin gene expression in the rat brain. J Mol Neurosci. 2004;22(3):213-22. PubMed PMID: 14997015. IF 2,504
45: Di Benedetto M, Feliciani D, D'Addario C, Izenwasser S, Candeletti S, Romualdi P. Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS. Brain Res Mol Brain Res. 2004 Aug 23;127(1-2):115-20. PubMed PMID: 15306127.IF 2,728
46: Aparicio LC, Candeletti S, Binaschi A, Mazzuferi M, Mantovani S, Di Benedetto M, Landuzzi D, Lopetuso G, Romualdi P, Simonato M. Kainate seizures increase nociceptin/orphanin FQ release in the rat hippocampus and thalamus: a microdialysis study. J Neurochem. 2004 Oct;91(1):30-7. PubMed PMID: 15379884. IF 4,061
47: D'Addario C, Di Benedetto M, Izenwasser S, Candeletti S, Romualdi P. Differential time course of effects of kappa-opioid agonist treatment on dynorphin A levels and kappa-opioid receptor density. J Mol Neurosci. 2004;24(2):307-14. PubMed PMID: 15456944.IF 2,504
48: Sandrini M, Vitale G, Pini LA, Lopetuso G, Romualdi P, Candeletti S. Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. Eur J Pharmacol. 2005 Jan 10;507(1-3):43-8. Epub 2004 Dec 15. PubMed PMID: 15659293.IF 2,516
49: Marti M, Mela F, Fantin M, Zucchini S, Brown JM, Witta J, Di Benedetto M, Buzas B, Reinscheid RK, Salvadori S, Guerrini R, Romualdi P, Candeletti S, Simonato M, Cox BM, Morari M. Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease. J Neurosci. 2005 Oct 19;25(42):9591-601. PubMed PMID: 16237164.IF 7,115
50: Di Benedetto M, D'addario C, Candeletti S, Romualdi P. Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain. Neuroscience. 2006;137(1):187-96. Epub 2005 Nov 10. PubMed PMID: 16289352.IF 3,380
51: Király KP, Riba P, D'Addario C, Di Benedetto M, Landuzzi D, Candeletti S, Romualdi P, Furst S. Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxymetopon and oxycodone-6-oxime. Brain Res Bull. 2006 Jul 31;70(3):233-9. Epub 2006 Jun 2. PubMed PMID: 16861108.IF 2,818
52: Raffaeli W, Samolsky Dekel BG, Landuzzi D, Caminiti A, Righetti D, Balestri M, Montanari F, Romualdi P, Candeletti S. Nociceptin levels in the cerebrospinal fluid of chronic pain patients with or without intrathecal administration of morphine. J Pain Symptom Manage. 2006 Oct;32(4):372-7. PMID: 17000354.IF 2,503
53: D'Addario C, Di Benedetto M, Izenwasser S, Candeletti S, Romualdi P. Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. Neuroscience. 2007 Jan 5;144(1):157-64. Epub 2006 Oct 19. PubMed PMID: 17055175.IF 3,380
54: Di Benedetto M, D'Addario C, Candeletti S, Romualdi P. Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors. Brain Res. 2007 Jan 12;1128(1):33-9. Epub 2006 Nov 27. PubMed PMID: 17125745.IF 2,728
55: Candeletti S, Lopetuso G, Cannarsa R, Cavina C, Romualdi P. Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS. J Mol Neurosci. 2006;30(3):341-7. PubMed PMID: 17401159.IF 2,504
56: Romualdi P, Di Benedetto M, D'Addario C, Collins SL, Wade D, Candeletti S, Izenwasser S. Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions. J Mol Neurosci. 2007;31(2):159-64. PubMed PMID: 17478889.IF 2,504
57: D'Addario C, Di Benedetto M, Candeletti S, Romualdi P. The kappa-opioid receptor agonist U-69593 prevents cocaine-induced phosphorylation of DARPP-32 at Thr(34) in the rat brain. Brain Res Bull. 2007 Jun 15;73(1-3):34-9. Epub 2007 Feb 20. PubMed PMID: 17499634.IF 2,818
58: Rubino T, Vigano' D, Realini N, Guidali C, Braida D, Capurro V, Castiglioni C, Cherubino F, Romualdi P, Candeletti S, Sala M, Parolaro D. Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. Neuropsychopharmacology. 2008 Oct;33(11):2760-71. doi: 10.1038/sj.npp.1301664. Epub 2008 Jan 2. PubMed PMID: 18172430.IF 7,991
59: Cannarsa R, Landuzzi D, Cavina C, Candeletti S, Romualdi P. Kainic acid down-regulates NOP receptor density and gene expression in human neuroblastoma SH-SY5Y cells. J Mol Neurosci. 2008 Jun;35(2):171-7. doi:10.1007/s12031-008-9038-x. Epub 2008 Feb 20. PubMed PMID: 18286384. IF 2,504
60: Marie-Claire C, Palminteri S, Romualdi P, Noble F. Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice. Neuropharmacology. 2008 Jun;54(7):1107-11. doi: 10.1016/j.neuropharm.2008.03.001. Epub 2008 Mar 8. PMID: 18410947.IF 4,814
61: Di Benedetto M, Cavina C, D'Addario C, Leoni G, Candeletti S, Cox BM, Romualdi P. Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP+ and 6-OHDA lesioned rats. Neuropharmacology. 2009 Mar;56(4):761-7. doi: 10.1016/j.neuropharm.2008.12.009. PubMed PMID: 19162046; PubMed Central PMCID: PMC2680584.IF 4,814
62: Marti M, Sarubbo S, Latini F, Cavallo M, Eleopra R, Biguzzi S, Lettieri C, Conti C, Simonato M, Zucchini S, Quatrale R, Sensi M, Candeletti S, Romualdi P, Morari M. Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease. Mov Disord. 2010 Aug 15;25(11):1723-32. doi: 10.1002/mds.23271. PubMed PMID: 20589874.IF 4,505
63: Buccellato E, Carretta D, Utan A, Cavina C, Speroni E, Grassi G, Candeletti S, Romualdi P. Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis. J Ethnopharmacol. 2011 Feb 16;133(3):1033-8. doi: 10.1016/j.jep.2010.11.035. Epub 2010 Nov 19. PubMed PMID: 21094240.IF 3,014.
64: D'Addario C, Johansson S, Candeletti S, Romualdi P, Ögren SO, Terenius L, Ekström TJ. Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. FASEB J. 2011 Mar;25(3):1069-75. doi: 10.1096/fj.10-168534. Epub 2010 Nov 24. PubMed PMID: 21106935.IF 5,712
65: Di Benedetto M, Bastías Candia Sdel C, D'Addario C, Porticella EE, Cavina C, Candeletti S, Romualdi P. Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb;383(2):169-78. doi: 10.1007/s00210-010-0587-5. Epub 2010 Dec 23. PubMed PMID: 21181116. IF 2,728
66: D'Addario C, Caputi FF, Rimondini R, Gandolfi O, Del Borrello E, Candeletti S, Romualdi P. Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. Addict Biol. 2011 Apr 20. doi: 10.1111/j.1369-1600.2011.00326.x. [Epub ahead of print] PubMed PMID: 21507157.IF 4,833
67: Cannarsa R, Carretta D, Lattanzio F, Candeletti S, Romualdi P. ?(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells. J Mol Neurosci. 2012 Feb;46(2):285-92. doi: 10.1007/s12031-011-9552-0. Epub 2011 May 21. PubMed PMID: 21603976.IF2,504
68: Arosio B, Bulbarelli A, Bastias Candia S, Lonati E, Mastronardi L, Romualdi P, Candeletti S, Gussago C, Galimberti D, Scarpini E, Dell'Osso B, Altamura C, MacCarrone M, Bergamaschini L, D'Addario C, Mari D. Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease. Neurodegener Dis. 2012;10(1-4):207-11. doi: 10.1159/000333799. Epub 2012 Jan 17. PubMed PMID: 22261503.IF3,056
69: D'Addario C, Dell'Osso B, Palazzo MC, Benatti B, Lietti L, Cattaneo E, Galimberti D, Fenoglio C, Cortini F, Scarpini E, Arosio B, Di Francesco A, Di Benedetto M, Romualdi P, Candeletti S, Mari D, Bergamaschini L, Bresolin N, Maccarrone M, Altamura AC. Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. Neuropsychopharmacology. 2012 Jun;37(7):1647-55. doi: 10.1038/npp.2012.10. Epub 2012 Feb 22. PubMed PMID: 22353757; PubMed Central PMCID: PMC3358733.IF 7.991
70: Gálvez-Llompart, M., Zanni, R., Romualdi, P., García-Domenech, R. Selection of nutraceutical compounds as COX inhibitors by molecular topology , Medicinal Chemistry Research 2012, Pages 1-12 IF 1,100
71: D'Addario C, Caputi FF, Ekström TJ, Di Benedetto M, Maccarrone M, Romualdi P, Candeletti S. Ethanol Induces Epigenetic Modulation of Prodynorphin and Pronociceptin Gene Expression in the Rat Amygdala Complex. J Mol Neurosci. 2013 Feb;49(2):312-9.Jun 10. [Epub ahead of print] PubMed PMID: 22684622.IF 2,504
72: Aujla H, Cannarsa R, Romualdi P, Ciccocioppo R, Martin-Fardon R, Weiss F. Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal. Addict Biol. 2013 May;18(3):467-79. doi: 10.1111/j.1369-1600.2012.00466.x. [Epub ahead of print] PubMed PMID: 22804785; PubMed Central PMCID: PMC3477306.IF 4,833
73: D'Addario C, Caputi FF, Rimondini R, Gandolfi O, Del Borrello E, Candeletti S, Romualdi P.Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. Addict Biol. 2013 May;18(3):425-33.
74: Bastías-Candia S, Di Benedetto M, D'Addario C, Candeletti S, Romualdi P.Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ-NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease. Environ Toxicol. 2013 Dec 23. doi: 10.1002/tox.21943.
75: Gallelli L, Galasso O, Falcone D, Southworth S, Greco M, Ventura V, Romualdi P, Corigliano A, Terracciano R, Savino R, Gulletta E, Gasparini G, De Sarro G. The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial. Osteoarthritis Cartilage. 2013 Sep;21(9):1400-8.
76: Caputi FF, Lattanzio F, Carretta D, Mercatelli D, Candeletti S, Romualdi P Morphine and fentanyl differently affect MOP and NOP gene expression in human neuroblastoma SH-SY5Y cells. J Mol Neurosci. 2013 Oct;51(2):532-8.
77: Fanelli A, Romualdi P, Vigano' R, Lora Aprile P, Gensini G, Fanelli G Non-selective non-steroidal anti-inflammatory drugs (NSAIDs) and cardiovascular risk. Acta Biomed. 2013 Jun 1;84(1):5-11
78: Caputi FF, Di Benedetto M, Carretta D, Bastias del Carmen Candia S, D'Addario C, Cavina C, Candeletti S, Romualdi P.Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Mar 3;49:36-46.
79: Lattanzio F, Carboni L, Carretta D, Rimondini R, Candeletti S, Romualdi P.Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice. Neuroscience. 2014 Jan 3;256:360-9.
80: Caputi FF, Carretta D, Tzschentke TM, Candeletti S, Romualdi P.Opioid Receptor Gene Expression in Human Neuroblastoma SH-SY5Y Cells Following Tapentadol Exposure. J Mol Neurosci. 2014 Feb 4.
81 Caputi FF, Carretta D, Lattanzio F, Palmisano M, Candeletti S, Romualdi P. Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. Environ Toxicol Pharmacol. 2015 Nov;40(3):895-900. doi: 10.1016/j.etap.2015.09.019. Epub 2015 Oct 3.
82 Caputi FF, Palmisano M, D'Addario C, Candeletti S, Romualdi P.Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice. Drug Alcohol Depend. 2015 Oct 1;155:68-75. doi: 10.1016/j.drugalcdep.2015.08.015. Epub 2015 Aug 28.
83. Carboni L, Lattanzio F, Candeletti S, Porcellini E, Raschi E, Licastro F, Romualdi P.Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients. Neurosci Lett. 2015 Sep 25;605:44-8. doi: 10.1016/j.neulet.2015.08.012. Epub 2015 Aug 11.
84. Kiraly K, Caputi FF, Hanuska A, Kató E, Balogh M, Köles L, Palmisano M, Riba P, Hosztafi S, Romualdi P, Candeletti S, Ferdinandy P, Fürst S, Al-Khrasani M. A new potent analgesic agent with reduced liability to produce morphine tolerance. Brain Res Bull. 2015 Aug;117:32-8. doi: 10.1016/j.brainresbull.2015.07.005. Epub 2015 Jul 30.
85 Maremmani I, Gerra G, Ripamonti IC, Mugelli A, Allegri M, Viganò R, Romualdi P, Pinto C, Raffaeli W, Coluzzi F, Gatti RC, Mammucari M, Fanelli G.The prevention of analgesic opioids abuse: expert opinion. Eur Rev Med Pharmacol Sci. 2015 Nov;19(21):4203-6.
Select item 26361715
86 Bastías-Candia S, Di Benedetto M, D'Addario C, Candeletti S, Romualdi P. Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ-NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease. Environ Toxicol. 2015 May-Jun;30(6):656-63.
87 Maremmani I, Gerra G, Ripamonti IC, Mugelli A, Allegri M, Viganò R, Romualdi P, Pinto C, Raffaeli W, Coluzzi F, Gatti RC, Mammucari M, Fanelli G. The prevention of analgesic opioids abuse: expert opinion. [http://www.ncbi.nlm.nih.gov/pubmed/26592848] Eur Rev Med Pharmacol Sci. 2015 Nov;19(21):4203-6.
88. Caputi FF, Carretta D, Lattanzio F, Palmisano M, Candeletti S, Romualdi P.
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. Environ Toxicol Pharmacol. 2015 Nov;40(3):895-900. doi: 10.1016/j.etap.2015.09.019. Epub 2015 Oct 3.
89 Lattanzio F, Carboni L, Carretta D, Candeletti S, Romualdi P. Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells. [http://www.ncbi.nlm.nih.gov/pubmed/26915812] Exp Toxicol Pathol. 2016 Feb 22. pii: S0940-2993(16)30006-9. doi: 10.1016/j.etp.2016.02.001. [Epub ahead of print]
90 , Vellucci R, Fanelli G, Pannuti R, Peruselli C, Adamo S, Alongi G, Amato F, Consoletti L, Lamarca L, Liguori S, Lo Presti C, Maione A, Mameli S, Marinangeli F, Marulli S, Minotti V, Miotti D, Montanari L, Moruzzi G, Palermo S, Parolini M, Poli P, Tirelli W, Valle A, Romualdi P.What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion. [http://www.ncbi.nlm.nih.gov/pubmed/26755179] Working Group Nientemale DEI Drugs. 2016 Mar;76(3):315-30. doi: 10.1007/s40265-015-0519-2.
91.Erratum to: What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion. Working Group Nientemale DEI., Vellucci R, Fanelli G, Pannuti R, Peruselli C, Adamo S, Alongi G, Amato F, Consoletti L, Lamarca L, Liguori S, Lo Presti C, Maione A, Mameli S, Marinangeli F, Marulli S, Minotti V, Miotti D, Montanari L, Moruzzi G, Palermo S, Parolini M, Poli P, Tirelli W, Valle A, Romualdi P. Drugs. 2016 Apr;76(6):731-2. doi: 10.1007/s40265-016-0563-6. No abstract available.
92. Caputi FF, Carboni L, Mazza D, Candeletti S, Romualdi P.Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells. [http://www.ncbi.nlm.nih.gov/pubmed/26922280] Drug Alcohol Depend. 2016 Apr 1;161:265-75. doi: 10.1016/j.drugalcdep.2016.02.012. Epub 2016 Feb 16.
93. Working Group Nientemale DEI., Vellucci R, Fanelli G, Cortesi PA, Pannuti R, Peruselli C, Romualdi P.Reply-Letter to the Editor: What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion. Drugs. 2016 Jul;76(10):1063-5. doi: 10.1007/s40265-016-0594-z.
94. Romualdi P, Candeletti S. Fentanyl citrate sublingual formulation (Vellofent®) for quick BTcP hindering. Minerva Med. 2016 Apr;107(2):114-22. Review.
95. Caputi F.F., Palmisano M., Carboni L., Candeletti S.,Romualdi P. Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and chronic 3,4-methylenedioxy-methamphetamine (MDMA) exposure. Pharmacol Res. 2016, 114,209-218.
96. Carboni L, Romoli B, Romualdi P, Zoli M.Repeated nicotine exposure modulates prodynorphin and pronociceptin levels in the reward pathway. Drug Alcohol Depend. 2016 Sep 1;166:150-8. doi: 10.1016/j.drugalcdep.2016.07.002.
97. Palmisano M., Mercatelli D., Caputi F.F., Carretta D., Romualdi P., Candeletti S. N/OFQ system in brain areas of nerve-injured mice: its role in different aspects of neurophatic pain. Genes Brain Behav. 2017 Jun;16(5):537-545. doi: 10.1111/gbb.12365. Epub 2017 Jan 10.
98. D'Addario C, Candia SB, Arosio B, Di Bartolomeo M, Abbate C, Casè A, Candeletti S, Romualdi P, Damanti S, Maccarrone M, Bergamaschini L, Mari D. Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report. J Neurol Sci. 2017 Jan 15;372:211-216. doi: 10.1016/j.jns.2016.11.052.
99. Romualdi P, Santi P, Candeletti S. Alghedon Fentanyl Transdermal System. Minerva Med. 2017 Apr;108(2):169-175. doi: 10.23736/S0026-4806.16.04930-2. Review.
100.Coluzzi F, Fornasari D, Pergolizzi J, Romualdi P. From acute to chronic pain: tapentadol in the progressive stages of this disease entity. [https://www.ncbi.nlm.nih.gov/pubmed/28429337] Eur Rev Med Pharmacol Sci. 2017 Apr;21(7):1672-1683.
101.Peana AT, Sánchez-Catalán MJ, Hipólito L, Rosas M, Porru S, Bennardini F, Romualdi P, Caputi FF, Candeletti S, Polache A, Granero L, Acquas E. Mystic Acetaldehyde: The Never-Ending Story on Alcoholism. [https://www.ncbi.nlm.nih.gov/pubmed/28553209] Front Behav Neurosci. 2017 May 11;11:81. doi: 10.3389/fnbeh.2017.00081. eCollection 2017. Review.
102.Coluzzi F, Bifulco F, Cuomo A, Dauri M, Leonardi C, Melotti RM, Natoli S, Romualdi P, Savoia G, Corcione A.The challenge of perioperative pain management in opioid-tolerant patients. [https://www.ncbi.nlm.nih.gov/pubmed/28919771] Ther Clin Risk Manag. 2017 Sep 5;13:1163-1173. doi: 10.2147/TCRM.S141332. eCollection 2017. Review.
103.Vellucci R., Mediati R.D., Gasperoni S., Mammuccari M., Marinangeli F., Romualdi P., Assessment and treatment of breakthrough cancer pain: from theory to clinical practice. J. Pain Res., 2017, 10:2147-2155. Open Access DovePress. doi: 10.2147/JPR.S135807. eCollection 2017. Review.
104. Caputi F.F., Acquas E., Kasture S., Ruiu S., Candeletti S., Romualdi P. The standardized Withania somnifera root extract affects basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells. BMC Complement Altern Med. 2018 Jan 10;18(1):9. doi: 10.1186/s12906-017-2065-9.
105 Francesca Felicia Caputi, Laura Rullo, Marco Caprini, Rocco Liguori, Sanzio Candeletti, Patrizia Romualdi. Cerebral gene expression changes in the alpha-galactosidase A deficient mouse: potential substrates underlying the neurological hallmarks of Fabry disease. Original research article. Submitted to Molecular Genetics and Metabolism, 2019.
106. Freo U,Romualdi P, Kress HG. Tapentadol for neuropathic pain: a review of clinical studies. [https://www.ncbi.nlm.nih.gov/pubmed/31190965] J Pain Res. 2019 May 16;12:1537-1551. doi: 10.2147/JPR.S190162. eCollection 2019. Review.
107. Romualdi P, Grilli M, Canonico PL, Collino M, Dickenson AH. Pharmacological rationale for tapentadol therapy: a review of new evidence. [https://www.ncbi.nlm.nih.gov/pubmed/31190962] J Pain Res. 2019 May 16;12:1513-1520. doi: 10.2147/JPR.S190160. eCollection 2019. Review.
108. Caputi FF, Rullo L, Stamatakos S, Candeletti S,Romualdi P. Interplay between the Endogenous Opioid System and Proteasome Complex: Beyond Signaling. [https://www.ncbi.nlm.nih.gov/pubmed/30901925] Int J Mol Sci. 2019 Mar 21;20(6). pii: E1441. doi: 10.3390/ijms20061441. Review.
109. Caputi FF, Caffino L, Candeletti S, Fumagalli F,Romualdi P. Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens. [https://www.ncbi.nlm.nih.gov/pubmed/30818133] Drug Alcohol Depend. 2019 Apr 1;197:127-133. doi: 10.1016/j.drugalcdep.2019.01.006. Epub 2019 Feb 13.
110. Caputi FF,Romualdi P, Candeletti S. Regulation of the Genes Encoding the ppN/OFQ and NOP Receptor. [https://www.ncbi.nlm.nih.gov/pubmed/30689088] Handb Exp Pharmacol. 2019 Jan 29. doi: 10.1007/164_2018_196. [Epub ahead of print]
111. Caputi FF, Nicora M, Simeone R, Candeletti S,Romualdi P. Tapentadol: an analgesic that differs from classic opioids due to its noradrenergic mechanism of action. [https://www.ncbi.nlm.nih.gov/pubmed/30667206] Minerva Med. 2019 Feb;110(1):62-78. doi: 10.23736/S0026-4806.18.05909-8. Review.
112. Mercadante S,Romualdi P. The therapeutic potential of novel kappa opioid receptor-based treatments. [https://www.ncbi.nlm.nih.gov/pubmed/30666905] Curr Med Chem. 2019 Jan 21. doi: 10.2174/0929867326666190121142459. [Epub ahead of print]
113. Caputi FF, Rullo L, Acquas E, Ciccocioppo R, Candeletti S,Romualdi P. Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine. [https://www.ncbi.nlm.nih.gov/pubmed/30503841] Pharmacol Res. 2019 Jan;139:422-430. doi: 10.1016/j.phrs.2018.11.033. Epub 2018 Nov 29.
114. Carboni L, Romoli B, Bate ST,Romualdi P, Zoli M. Increased expression of CRF and CRF-receptors in dorsal striatum, hippocampus, and prefrontal cortex after the development of nicotine sensitization in rats. [https://www.ncbi.nlm.nih.gov/pubmed/29857328] Drug Alcohol Depend. 2018 Aug 1;189:12-20. doi: 10.1016/j.drugalcdep.2018.04.027. Epub 2018 May 29.
115. Palmisano M, Caputi FF, Mercatelli D,Romualdi P, Candeletti S. Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. [https://www.ncbi.nlm.nih.gov/pubmed/29430855] Genes Brain Behav. 2019 Jul;18(6):e12467. doi: 10.1111/gbb.12467. Epub 2018 Mar 15.
Pubblicazioni
B) Short Communications con Referees:
1. FERRI S., CANDELETTI S., ROMUALDI P., SPAMPINATO S., Effects of opioid and nonopioid peptides intrathecally administered on nociceptive transmission, Pain, Suppl.2, S230, 1984.
2. CANDELETTI S., CAVICCHINI E., FERRI S., ROMUALDI P., SPAMPINATO S., SPERONI E. Characterization of antinociceptive profiles of intrathecal dynorphin and calcitonin-related peptides, Brit. J. Pharmacol., 86, 528P, 1985.
3. FERRI S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., Effect of calcitonin-related peptides on nociception and thermoregulation of the rat. Pain (Suppl. 4), S46, 1987.
4. ROMUALDI P., COX B.M., FERRI S., Evidence for the presence of VIP 22-28 heptapeptide in rat brain cortex, Pharmacol. Res. Commun., 20, Suppl. 1, 35-36, 1988.
5. ROMUALDI P., FERRI S., SCHOENBERG D.R., COX B.M., Prodynorphin gene expression in rat brain by "in situ" hybridization, Pharmacol. Res. Commun., 20, Suppl. 2, 330, 1988.
6. ROMUALDI P., CAVICCHINI E., CANDELETTI E., FERRI S., Interplay between VIP and serotonergic system in rat CNS, Pharmacol. Res. Commun., 20, Suppl. 2, 329, 1988.
7. FERRI S., ROMUALDI P., SPAMPINATO S., Regulation of opioid peptide gene expression by antisense RNA. Neurosci. Lett. (Suppl. 33), S86, 1988.
8. SALVADORI S., MARASTONI M., BALBONI G., SCARANARI V., SANTAGADA V., ROMUALDI P., FERRI S., TOMATIS R., Synthesis and activity of antiflamin, In: Peptides 1990, Giralt E. and Andreu D. Eds. Leiden, 1991, pp. 757-758.
9. ROMUALDI P., LESA G., DONATINI A., FERRI S., Changes in VIP-related peptides after seizures in rat brain, Neuropeptides, 22, 57, 1992.
10. ROMUALDI P., SIMONATO M., BREGOLA G., DONATINI A., BIANCHI C., BEANI L., FERRI S., Prodynorphin gene expression in different rat brain areas in the kindling model of epilepsy, Brit. J. Pharmacol., 111, 126P, 1994.
11. ROMUALDI P., DONATINI A., FERRI S., Chronic bupropion and imipramine differently affect prodynorphin gene expression., Trends in Neuroscience, 20, suppl.9, 34, 1997.
12. ROMUALDI P., CAPOBIANCO A., FERRI S., Prodynorphin gene expression regulation by antidepressants in rat brain. Naunyn-Schmiedberg, Archives of Pharmacology, 45, 567, 1998.
Pubblicazioni
C) Congressi:
1. FERRI S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., SPAMPINATO S., Modulation of nociception by intrathecally administered calcitonin and dynorphin, 3rd Capo Boi Conference on Neuroscience, Abstr. 28, Villasimius, 29 May-2 June 1983.
2. SPAMPINATO S., CANDELETTI S., ROMUALDI P., RUSSO A., S. STANZANI, FERRI S., Effects of hypothalamic lesions on the content of dynorphin immunoreactivity in pituitary, Proc. International Narcotic Research Conference, Abstr. 111, Garmisch-Partenkirchen, 26 June-July 1 1983.
3. FERRI S., CANDELETTI S., CAVICCHINI E., CHIECO P., ROMUALDI P., SPERONI E., SPAMPINATO S., SPADARO C., Effects of opioid peptides on gastric lesions, 1st Int. Meeting of the Italian Society of Endocrinology. Recent Progress in opioid Research. Central and Peripheral Endorphins, Abstr. pag. 53, Viareggio, 6-8 Ottobre 1983.
4. CANDELETTI S., ROMUALDI P., CAVICCHINI E., FERRI S., Modulazione della trasmissione nocicettiva operata a livello spinale da peptidi endogeni oppioidi e non oppioidi, XX Congresso Nazionale A.I.D.M., Abstr. pag. 4, Bologna, 14-16 Ottobre 1983.
5. SPAMPINATO S., CANDELETTI S., ROMUALDI P., SPERONI E., CAVICCHINI E., FERRI S., Modulation of the spinal nociceptive transmission by intrathecal opioid and non opioid peptides, 5th Joint Meeting Italian and Soviet Neuropharmacologists, Abstr. pag. 2, Florence, 23-25 November 1983.
6. GARUTI L., GIOVANNINETTI G., SPERONI E., ROMUALDI P., Calcio antagonisti a base indolica, Atti IV Con. Naz. Div. Chim. Farmaceutica, Palermo, 18- 22 Ottobre 1983, p.143.
7. FERRI S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., SPAMPINATO S., Opioid receptors mediating the antinociceptive effect of dynorphin at spinal cord level, It. Congr. Neuroreceptor Mechanisms in Human Diseases, Abstr. pag. 25, Florence, 21-23 March 1984.
8. CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPAMPINATO S., SPERONI E., FERRI S., Antinociceptive activity of intrathecal opioid and non opioid peptides ascertained by different analgesimetric procedures, 1st World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Abstr. pag. 87, Venice, 16-18 April 1984.
9. CANDELETTI S., FERRI G-L., ROMUALDI P., SPAMPINATO S., SOIMERO L., FERRI S., LABO' G., Evidence for the presence of immunoreactive dynorphin throughout the human gastrointestinal tract, Opioid Peptides in Periphery, Abstr. pag. 54, Rome, 23-25 May 1984.
10. FERRI S., CANDELETTI S., SPAMPINATO S., ROMUALDI P., CAVICCHINI E., SPERONI E., Basic pharmacology of the manipulation of the analgesizing system, 1st Congress of the Mediterranean Society of Therapy, Florence, 10-15 June 1984.
11. SPAMPINATO S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., RUSSO A., STANZANI S., FERRI S., Regulation of immunoreactive dynorphin in rat anterior pituitary, 14th C.I.N.P. Congress, Abstr. 668, Florence, 19-23 June 1984.
12. SPAMPINATO S., CANDELETTI S., ROMUALDI P., CAVICCHINI E., PANERAI A.E., FERRI S., Possible involvement of the spinal dynorphinergic system in stressinduced analgesia, Proc. International Narcotic Research Conference, Abstr. P13, Cambridge, 23-28 July 1984.
13. SPAMPINATO S., CANDELETTI S., ROMUALDI P., FERRI S., Opioid receptors mediating antinociceptive and motor effects of dynorphin A at spinal level, 9th Int. Congr. of Pharmacology, Abstr. 273, London, 29 July-4 August 1984.
14. SPAMPINATO S., CANDELETTI S., ROMUALDI P., CAVICCHINI E., FERRI S., Effect of intrathecal opioid and non opioid peptides on nociceptive transmission, XXII Congresso della Società Italiana di Farmacologia, Abstr. pag. 442, Bologna, 10-13 Ottobre 1984.
15. CANDELETTI S., CAVICCHINI E., FERRI S., ROMUALDI P., SPERONI E., SPAMPINATO S., Impact of opioid and non opioid peptides on nociceptive transmission at spinal cord level, Ist Congress of Italian Soc. of Neuroscience, Abstr.174, Rome, 12-15 dicembre 1984.
16. FERRI S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., SPAMPINATO S., Coinvolgimento di peptidi oppioidi e non oppioidi nella trasmissione nocicettiva a livello spinale. VIII Congresso Nazionale dell'AISD, Verona, 4-5 maggio 1985.
17. SPAMPINATO S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., FERRI S., Possible involvement of the spinal dynorphinergic system in the response to aversive stimuli. International Narcotic Research Conference 1985, North Fallmouth MA, USA, June 23-28, 1985.
18. FERRI S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., SPAMPINATO S., Possible involvement of the spinal dynorphinergic system in nociceptive mechanisms. 4Congr. Hungarian Pharmacological Society, Budapest, August 1985.
19. SPAMPINATO S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., FERRI S., Characterization of antinociceptive profiles of intrathecal dynorphin and calcitonin-related peptides. Proc. British Pharmacological Society, Joint Meeting with S.I.F., Edinburgh, September 1985.
20. FERRI S., CANDELETTI S., ROMUALDI P., SPAMPINATO S., Pharmacodynamic profiles of prodynorphin-derived peptides. Int. Symposium on Pain Therapy, Rome, September 1985.
21. CANDELETTI S., CAVICCHINI E., FERRI S., ROMUALDI P., SPAMPINATO S., SPERONI E., Possible relationships between proopiomelanocortin and prodynorphin derived peptides. 4th Capo Boi Conference on Neuroscience. Villasimius, June 2-7, 1985.
22. SPAMPINATO S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., FERRI S., Effect of neuropeptides on the modulation of pain and motility. International Conference on Pain and Motility. From physiology to overt behaviour. Milano, March 18-21, 1986.
23. FERRI S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPAMPINATO S., SPERONI E., Trattamenti farmacologici e non farmacologici per il controllo del dolore. Progetto Finalizzato "Medicina Preventiva e Riabilitativa". Risultati e Prospettive, Roma, 17-21 marzo 1986.
24. FERRI S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPAMPINATO S., SPERONI E., Investigations on dynorphin structurally-related opioid peptides. I. Impact on nociceptive transmission. II. Regulation of pituitary content. VI Joint Meeting of Soviet-Italian Neuropharmacologist, Tashkent, U.S.S.R., April 19-26, 1986.
25. SPAMPINATO S., CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPERONI E., FERRI S., Differential effects of selective brain lesions on CNS ir-dynorphin. Proc. International Narcotic Research Conference, San Francisco, CA, U.S.A., 6-11 July 1986.
26. CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPAMPINATO S., SPERONI E., FERRI S., Pharmacology of neuropeptides in nociceptive transmission. International Workshop on Trends in Cluster Headache, Chieti-Montesilvano, September 7-10, 1986.
27. CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPADARO C., SPERONI E., SPAMPINATO S., FERRI S., Comparazione dell'effetto antinocicettivo e ipertermizzante di alcuni peptidi correlati alla calcitonina. Simposio Internazionale "La Calcitonina nell'Osteoporosi". Stato dell'arte, attualità e prospettiva, Giardini Naxos, 26-27 settembre 1986, Abstr. no. 131.
28. CANDELETTI S., CAVICCHINI E., ROMUALDI P., SPAMPINATO S., SPERONI E., FERRI S., Lesioni di aree cerebrali e livelli centrali di dinorfine. XXIII Congresso Nazionale della Società Italiana di Farmacologia, Sanremo, 6-8 Ottobre 1986.
29. SPAMPINATO S., CANDELETTI S, ROMUALDI P. and FERRI S., Estrogen influence on hypothalamic and pituitary dynorphins, Proc. First Joint Meet. Ital. and Dutch Pharmacol. Soc., Florence, May 10-13, 1987, p.29.
30. SPAMPINATO S., CANDELETTI S., CANOSSA M., CAVICCHINI E., ROMUALDI P., FERRI S., Estrogen-induced changes in pituitary ir-dynorphin in the rat. Regulatory roles of opioid peptides. II International Congress of Neuroscience. Budapest, August 14-15, 1987, Atti p. 80.
31. ROMUALDI P., SCHOENBERG D.R., COX B.M., STROCCHI P., FERRI S., CNS localization of prodynorphin mRNA by "in situ hybridization". Biotech RIA '88 Molecular Probes. Florence, April 11-13, 1988, p. 174.
32. ROMUALDI P., SPAMPINATO S., Gene expression of prodynorphin in rat brain evaluated by "in sity hybridization". Joint Soviet-Italian Meet. on Neuropsychopharmacology. Copanello, September 19-21, 1988, p. 47.
33. ROMUALDI P., FERRI S., COX B.M., SCHOENBERG D.R., Prodynorphin gene expression in the rat brain. European Conference on Biotechnology. Verona, November 7-8 1988, p. 231-232.
34. ROMUALDI P., LESA G., FERRI S., Chronic opiates affect prodynorphin gene expression, Post Febs '89. Società Italiana di Biochimica. Symposium on Biochemistry for Biotechnology. Villa Olmo, Como, July 10-11, 1989, pp.31-32.
35. ROMUALDI P., LESA G., FERRI S., The opioid antagonist naloxone influences prodynorphin gene expression. IV Riunione Gruppo Inter-Regionale Società Italiana di Farmacologia. Bologna, 15 Dicembre 1989, pp. 1-2.
36. PINCELLI C., FANTINI F., ROMUALDI P., LESA G., GIANNETTI A., Increased VIP levels in lesional skin of psoriasis. Society for Investigative Dermatology. Washington, May 2-5 1990.
37. ROMUALDI P., LESA G., FERRI S., Chronic exposure to opioid agonists and antagonist affect prodynorphin gene expression. 2nd Joint Meeting Italian and Hungarian Pharmacological Societies. Budapest, May 14-15, 1990.
38. PINCELLI C., FANTINI F., ROMUALDI P., LESA G., GIROLIMONI G., MASSIMI P., GIANNETTI A., Increased VIP levels in lesional skin of atopic dermatitis, 1st International Congress ISNIM. Florence, May 23-26, 1990.
39. PINCELLI C., FANTINI F., BARANZONI N., ROMUALDI P., LESA G., SEVIGNANI C., GIANNETTI A. Polipeptide vasoattivo intestinale (VIP) e psoriasi: studio radioimmunologico, 66° Cong. Naz. Soc. It. Derm. Ven., Bologna, 30 maggio-2 giugno 1990, Abstr. no. 37.
40. ROMUALDI P., LESA G., FERRI S., Differential changes in rat brain levels of ir-VIP after pentylenetetrazole seizures. IUPHAR XIth International Congress of Pharmacology. Amsterdam, July 2-6, 1990.
41. SALVADORI S., MARASTONI M., BALBONI G., ROMUALDI P., FERRI S., TOMATIS R., Synthesis and bioactivity of "antiflammins". 21st European Peptide Symposium, Platja d'Aro, September 2-8, 1990, Abs. 288.
42. FANTINI F., PINCELLI C., ROMUALDI P., LESA G., SEIDENARI S., Cutaneous VIP levels in the elicitation phase of allergic contact dermatitis. 9th Symposium Adv. in Skin Pharmacology. Cannes, October 4-6, 1990, p. 34-35.
43. FANTINI F., PINCELLI C., ROMUALDI P., LESA G., GIROLOMONI G., GIANNETTI A. Increased vasoactive intestinal polypeptide levels in lesional skin of atopic dermatitis, 20th Meet. Eur. Soc. Derm. Res., Turin, 1990, Abstr. no. 88.
44. FANTINI F., PINCELLI C., ROMUALDI P., LESA G., GIANNETTI A., Quantification of Substance P cutaneous levels in atopic dermatitis. 21st Ann. Meet. Eur. Soc. Derm. Res. Copenhagen, July 10-14, 1991, Abs. 54.
45. FANTINI F., PINCELLI C., ROMUALDI P., LESA G., GIANNETTI A., Substance P cutaneous levels are decreased in psoriasis, Proc. 5th Int. Psor. Symp., S. Francisco, CA, USA, August 10-14, 1991, p. 178.
46. FERRI S., CANDELETTI S., ROMUALDI P., SPAMPINATO S., CANOSSA M., LESA G., Sviluppo di sonde molecolari per lo studio dell'espressione genica di neuropeptidi. Convegno del Progetto Finalizzato CNR "Biotecnologie e Biostrumentazione". Genova, 22-26 Settembre 1991, p. 308.
47. ROMUALDI P., LESA G., Profilo farmacologico del neuropeptide VIP 22-28 di recente individuazione. Soc. It. Neuroscienze, Firenze, 28-30 Novembre 1991, p. 27.
48. ROMUALDI P., LESA G., NEGRI L., FERRI S., Opioid gene regulation by , k, opiate agonists. 3rd Joint Meet. Hungarian, Italian, Polish Pharmacol. Soc., Modena, June 8-10, 1992, p. 264-265.
49. FANTINI F., PINCELLI C., ROMUALDI P., LESA G., SEVIGNANI C., GIANNETTI A., Substance P and Vasoactive Intestinal Polypeptide in the pathogenesis of psoriatic lesions, 18th World congress of dermatology, New York, June 12-18, 1992, p. 63A.
50. ROMUALDI P., LESA G., NEGRI L., MELCHIORRI P., FERRI S., Chronic DAla2-Deltorphin I alters prodynorphin gene expression in rat brain. Proc. Int. Narc. Res. Conf., Keystone, Colorado, June 23-27, 1992, p. 143.
51. ROMUALDI P., LESA G., FERRI S., Regulation of opioid gene expression following chronic opiate treatment. XXVI Congresso della Società Italiana di Farmacologia, Napoli, 29 settembre - 3 ottobre, 1992, p. 16.
52. ROMUALDI P., DONATINI A., FERRI S., Regulation of prodynorphin gene expression by chronic opiate receptor agonists. Joint Meeting of Russian and Italian Neuropharmacologists. Molecular Pharmacology of the CNS, Urbino, October 14-16, 1992, p. 26.
53. ROMUALDI P., IZENWASSER S., COX B.M., FERRI S., Chronic cocaine administration affects opioid gene expression in rat brain. Proc. International Narcotic Research Conference, Skovde, Sweden, July 10-15, 1993, Abst. p. 80.
54. ROMUALDI P., DONATINI A., FERRI S., Opioid antagonists up-regulate prodynorphin gene expression in rat brain. Proc. International Narcotic Research Conference, Skovde, Sweden, July 10-15, 1993. Abst. p. 81.
55. ROMUALDI P., SIMONATO M., BREGOLA G., DONATINI A., BIANCHI C., BEANI L., FERRI S., Prodynorphin gene expression in different rat brain areas in the kindling model of epilepsy. Proc. British Pharmacological Society. V Joint Meeting, Roma, September 14-16, 1993. Abst. C158.
56. ROMUALDI P., DONATINI A., FERRI S., Central effects of the VIP-related neuropeptide VIP 22-28. III European Neuropeptide Club, Verona, October 14, 1993. Abst. 5.
57. ROMUALDI P., DONATINI A., FERRI S., Prodynorphin gene expression is affected by chronic exposure to opiates and cocaine. XII International Congress of Pharmacology, Montréal, Canada 24-29 July 1994. Abstr. p. 394.
58. ROMUALDI P., DONATINI A., FERRI S., Regulation of prodynorphin gene expression by chronic opiate agonists and antagonists. 10th Meeting of the European Society for Neurochemistry, Jerusalem, Istrael, 14-19 August 1994. Abstr. S56C.
59. ROMUALDI P., DONATINI A., FERRI S., , k and opioid antagonists up-regulate prodynorphin gene expression in rat brain. IV Joint Meeting of Hungarian, Italian and Polish Pharmacological Societies, Poznan, 19-21 September 1994. Abstr. p. 219.
60. CANDELETTI S., ROMUALDI P., FERRI S., Enhancement of prodynorphin gene expression in rat CNS after dorsal rhizotomy. XXVII Congresso Nazionale della Società Italiana di Farmacologia, Torino, 25-29 Settembre 1994. Abstr. p. 26.
61. ROMUALDI P., SIMONATO M., BREGOLA G., DONATINI A., BIANCHI C., BEANI L., FERRI S., Early changes in ir-dynorphin A content in the rat brain following kindled seizures. XXVII Congresso Nazionale della Società Italiana di Farmacologia, Torino, 25-29 Settembre 1994. Abstr. p. 358.
62. ROMUALDI P., DONATINI A., FERRI S., Regolazione dell'espressione genica del peptide oppioide prodinorfina dopo somministrazione cronica di oppiacei e cocaina. 7Congresso della Società di Psichiatria Biologica, S. Margherita di Pula-Cagliari, 4-7 Ottobre 1994. Abstr. p. 69.
63. ROMUALDI P., DONATINI A., FERRI S., Chronic methamphetamine affects prodynorphin gene expression in rat brain. First European Congress of Pharmacology, Milan, June 16-19, 1995, Abstr. p. 111.
64. ROMUALDI P., DONATINI A., FERRI S., Prodynorphin gene expression regulation by chronic methamphetamine in rat brain. XXVI International Narcotics Research Conference, St. Andrews, UK, July 9-13, 1995. Asbtr. T50.
65. ROMUALDI P., DONATINI A., FERRI S., Prodynorphin gene expression regulation by methamphetamine in mesocorticolimbic areas of rat brain, Proc. 3rd Joint Meet. French-Italian Pharmacol. Soc., Capri 23-25 May, 1996, Fund. Clin. Pharmacol., 10, 213, 1996.
66. ROMUALDI P., DONATINI A., FERRI S., Cocaine and methamphetamine differently affect prodynorphin gene expression in rat brain, VII Congress on University and Biotechnology Inn., Genova, 15-16 July 1996, p.53.
67. ROMUALDI P., DONATINI A., FERRI S., Dopaminergic involvement in methamphetamine-induced prodynorphin gene expression in rat mesocorticolimbic system, Proc. INRC, Long Beach, CA, 21-26 July 1996, P50.
68. SIMONATO M., BREGOLA G., DONATINI A., BIANCHI C., BEANI L., FERRI S., ROMUALDI P., Kindled seizure-induced c-fos and prodynorphin mRNA expressions are unrelated in the rat brain, II° Meet. of European Neuroscience, Strasbourg, France, 24-28 September 1996, abst. 113.20, p. 208.
69. BREGOLA G., DONATINI A., ROMUALDI P., SIMONATO M., Espressione di prodinorfina e di c-fos nel cervello di ratto in seguito a convulsioni da kindling, Proc. V Congr. Naz. Giovani Cultori delle Neuroscienze, Soc. It. Neuroscienze, Pisa, 12-14 dicembre 1996, abstr. R6.
70. ROMUALDI P., DONATINI A., FERRI S., Methamphetamine-induced prodynorphin gene expression and dopaminergic involvement in rat mesocorticolimbic system, Proc. XXVIII Nat. Congr. of It. Pharmacol. Soc., Bari, April 30-May 3, 1997, p.53.
71. ROMUALDI P., DONATINI A., FERRI S., Chronic bupropion and imipramine differently affect prodynorphin gene expression in rat brain., 6th World Congr. Biol. Psychiatry, Nice, France, June 2-7, 1997.
72. ROMUALDI P., DONATINI A., FERRI S., Chronic bupropion and imipramine differently affect prodynorphin gene expression., 7th Congr. Ital. Soc. Neurosciences, Brescia, September 20-23, 1997, Abstract P55.
73. ROMUALDI P., CAPOBIANCO A., DONATINI A., FERRI S., Prodynorphin gene expression regulation by chronic antidepressants, 6th Joint Meet. Italian, Hungarian and Polish Pharmacol. Soc., Pisa, May, 14-16, 1998, P163.
74. ROMUALDI P., CAPOBIANCO A., DONATINI A., FERRI S., The atypical antidepressant bupropion affects prodynorphin gene expression in rat brain. Proc. 29° Int. Narc. Res. Conf., Garmisch-Partenkirchen, 20-25 July 1998, Abstract Fr05, p.62.
75. ROMUALDI P., CAPOBIANCO A., FERRI S., Prodynorphin gene expression regulation by antidepressants in rat brain. 13th IUPHAR, Munchen, 26-31 July 1998, p.
76. SIMONATO S., BREGOLA G., BEANI L., CANDELETTI S., ROMUALDI P., Increased pronociceptin gene expression in the thalamic reticular nucleus following limbic seizures. 28th Ann. Meet. Soc. for Neuroscience, Los Angeles, November 7-12, 1998. Abstract no. 850.15, p. 2140.
77. ROMUALDI P., BREGOLA G., CAPOBIANCO A., SIMONATO M., Regionspecific changes in prodynorphin mRNA and ir-Dynorphin A levels afetr seizures. Regul. Peptides, vol. 80, 9th Meeting Europ. Neuropeptide Club, Ferrara, Italy, May 12-15, 1999, p. 130.
78. ROMUALDI P., CAPOBIANCO A., FERRI S., Dopaminergic involvement in cocaine-induced effects on prodynorphin gene expression in rat brain. Proc. XXIX Nat. Congr. It. Pharmacol. Soc., Florence, Italy, 20-23 June 1999, p. 42.
79. CANDELETTI S., BREGOLA G., ROMUALDI P., SIMONATO M., Kainateinduced limbic seizures increase pronociceptin gene expression. Proc. XXIX Nat. Congr. It. Pharmacol. Soc., Florence, Italy, 20-23 June 1999, p. 80.
80. ROMUALDI P. Molecular mechanisms underlying the effects of chronic exposure to addictive drugs. ATLA, vol. 27, special issue July 1999, Third World Congr. On Alternatives and Animal use in the Life Sci., 29 August-2 September 1999, Bologna, Italy, p. 75.
81. ROMUALDI P., CAPOBIANCO A., FERRI S., COX B.M., IZENWASSER S., Differential alterations in prodynorphin gene expression following chronic administration of GBR 12909 or cocaine, 29th Annual Meeting of the Society for Neuroscience, Miami Beach, FLA, USA, October 23-28, 1999, abs. 327.5, p. 811.
82. ROMUALDI P., MAIE I., FERRI S. "Ecstasy: acute and chronic effects on endogenous opioid system in rat CNS" La Neuropsicofarmacologia nel terzo millenio-XII Cong. Soc. It. Neuropsicofarmacologia (Cagliari, 7-10/6/2000) a cura di Biggio G. Fratta W.pp. 145-145, Societa' Italiana di Neuropsicofarmacologia, Cagliari, 2000
83. D'ADDARIO C., LANDUZZI D., FUSCONI E., ROMUALDI P., CANDELETTI S."Alterations of pronociceptin biosynthesis after acute and chronic morphine administrations in rat CNS"SIF-VII Convegno Nazionale dei Giovani Cultori delle Neuroscienze (Pisa, 5-7/12/2000) a cura di Corsini G.U. Giovannini L. Maggio R. Scalori V.pp. 54-54, Universita' degli Studi di Pisa- Societa' Italiana di Neuroscienze,
84. BREGOLA G., ZUCCHINI S., FRIGATI L., CANDELETTI S., ROMUALDI P., REINSCHEID R., SIMONATO M., Involvement of the nueropeptide orphanin FQ/nociceptin in kainate and kindling seizures and epileptogenesis, VI Workshop on Neurobiology of Epilepsy, Iguazù, Brazil, May 8-12, 2001.
85. BREGOLA G., ZUCCHINI S., FRIGATI L., CANDELETTI S., ROMUALDI P., REINSCHEID R., SIMONATO M., Involvement of the neuropeptide orphanin FQ/nociceptin in kainate and kinding seizures and epileptogenesis, Nat. Congr. It. Pharmacol. Soc., Genova, Italy, may 30-June 2, 2001, Pharmacol. Res. 43(A), 77, 2001.
86. ROMUALDI P., FERRI S., LANDUZZI D., FUSCONI E., D'ADDARIO C., CANDELETTI S., Modulation of pronociceptin gene expression in the rat brain, Nat. Congr. It. Pharmacol. Soc., Genoa, Italy, May 30-June 2, 2001, Pharmacol. Res. 43(A), 157, 2001.
87. CANDELETTI S., LANDUZZI D., D'ADDARIO C., ROMUALDI P., Acute and chronic morphine affect proOFQ/N gene expression in different rat brain areas, 32th International Narcotics Research Conference, Helsinki (Finland) July 14-19, 2001. Abstr. p. 43.
88. IZENWASSER S., CANDELETTI S., D'ADDARIO C., DI BENEDETTO M., COLLINS S.L., ROMUALDI P., Depletion of serotonin blocks the regulation of dynorphin by kappa-opioid agonists, 33th International Narcotics Research Conference, Asilomar, Pacific Grove, CA (USA) July 9-14, 2002. Abstr. p. 31.
89. COLLINS S.L., D'ADDARIO C., ROMUALDI P., CANDELETTI S., IZENWASSER S., Regulation of dynorphin gene expression by kappa-opioid agonists and cocaine, 33th International Narcotics Research Conference, Asilomar, Pacific Grove, CA (USA) July 9-14, 2002. Abstr. p. 70
90. D'ADDARIO C., IZENWASSER S., ROMUALDI P., CANDELETTI S., Regolazione dell'espressione genica della prodinorfina da parte dell'U-69593, agonista del recettore oppioide kappa, VII Convegno Monotematico S.I.F. "Aspetti Neurochimici e Farmacologici delle Dipendenze", Capri, 20 Settembre 2002. Abstr. O9.
91. DI BENEDETTO M., CANDELETTI S., ROMUALDI P., Effetti della fluoxetina sull'espressione genica del precursore oppioide prodinorfina nel SNC di ratto, VII Convegno Monotematico S.I.F. "Aspetti Neurochimici e Farmacologici delle Dipendenze", Capri, 20 Settembre 2002. Abstr. P3.
92. LANDUZZI D., ROMUALDI P., Effetti della morfina sull'espressione genica del recettore della nocicettina (NOP) in cellule SH-SY5Y, VII Convegno Monotematico, Aspetti Neurochimici e Farmacologici delle Dipendenze, Capri, 20 settembre 2002, p. 5.
93. COLLINS S.L., ROMUALDI P., CANDELETTI S., IZENWASSER S., Serotonin depletion decreases the effects of U-69593 on cocaine-stimulated activity, 32th Annual Meeting of The Society for Neuroscience, Orlando (FL, USA), November 2-7, 2002. Abstr. 608.9.
94. D'ADDARIO C., CANDELETTI S., COLLINS S.L., DI BENEDETTO M., IZENWASSER S., ROMUALDI P., Cocaine and fluoxetine produce opposite effects on dynorphin gene expression, 32th Annual Meeting of The Society for Neuroscience, Orlando (FL, USA), November 2-7, 2002. Abstr. 608.10.
95. DI BENEDETTO M., D'ADDARIO C., FELICIANI D., CANDELETTI S., ROMUALDI P., Effects of chronic nisoxetine on prodynorphin gene expression in rat CNS, 31° Congresso della Società Italiana di Farmacologia, Trieste, 26-29 Giugno 2003.
96. LANDUZZI D., D'ADDARIO C., DI BENEDETTO M., CEVOLANI A., ROMUALDI P., CANDELETTI S., Hiipocampal N/OFQ and NOP receptor alterations induced by morphine tolerance, 31° Congresso della Società Italiana di Farmacologia, Trieste, 26-29 Giugno 2003.
97. CANDELETTI S., FERRI S., ROMUALDI P., Comparison of the effects of a prolonged exposure to tramadol or morphine on prodynorphin gene expression, 34th International Narcotics Research Conference, 6-11 July, Perpignan, France.
98. ROMUALDI P., D'ADDARIO C., DI BENEDETTO M., IZENWASSER S., CANDELETTI S., Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on kappa-opioid receptor density, 34th International Narcotics Research Conference, 6-11 July, Perpignan, France.
99. CANDELETTI S., LANDUZZI D., D'ADDARIO C., DI BENEDETTO M., ROMUALDI P., Chronic morphine markedly affects the nociceptin/orphanin FQ system in the rat hippocampus, 34th International Narcotics Research Conference, 6-11 July, Perpignan, France.
100. Simonato M., Aparicio L., Bregola G., Zucchini S., Rodi D., Binaschi A., Mazzuferi M., D'Addario C., Landuzzi D., Di Benedetto M., Reinscheid R., Romualdi P. Candeletti S.: Involvement of the Neuropeptide Nociceptin/Orphanin FQ in Kainate Seizures. XLVI Congreso Nacional de Ciencias Fisiologicas. Aguascalientes, Mexico, 3-6 Agosto 2003.
Pubblicazioni
101. LANDUZZI D., D'ADDARIO C., DI BENEDETTO M., ROMUALDI P., CANDELETTI S., possible involvement of nociceptin/NOP endogenous system in morphine tolerance in the rat hippocampus, VIII Convegno Monotematico della Società Italiana di Farmacologia su "La Nocicettina/Orfanina FQ ed il suo recettore: recenti acquisizioni fisiofarmacologiche e prospettive farmacoterapeutiche", Camerino, 15 Settembre 2003.
102. MAZZUFERI M., SIMONATO M., APARICIO L., BREGOLA G., ZUCCHINI S., RODI D., BINASCHI A., D'ADDARIO C., LANDUZZI D., DI BENEDETTO M., REINSCHEID R., ROMUALDIi P., CANDELETTI S.: Involvement of the Neuropeptide Nociceptin/Orphanin FQ in Kainate Seizures. Convegno Monotematico della Società Italiana di Farmacologia su "La Nocicettina/Orfanina FQ ed il suo recettore: recenti acquisizioni fisiofarmacologiche e prospettive farmacoterapeutiche". Camerino, 15 Settembre 2003.
103. MAZZUFERI M., SIMONATO M., APARICIO L., BREGOLA G., ZUCCHINI S., RODI D., BINASCHI A., D'ADDARIO C., LANDUZZI D., DI BENEDETTO M., REINSCHEID R., ROMUALDIi P., CANDELETTI S. Involvement of the Neuropeptide Nociceptin/Orphanin FQ in Kainate Seizures. Società Italiana di Neuroscienze. Pisa, 26-28 Settembre 2003.
104. K. KIRÁLI, C. D'ADDARIO, M. DI BENEDETTO, D. LANDUZZI, P. RIBA, S. CANDELETTI, P. ROMUALDI, S. FÜRST, Alterations of the dynorphinergic system during tolerance development in rat brain by novel opioid compounds. EOC, Visegrad, Hungary, April –7, 2004, p.23.
105. M. DI BENEDETTO, D. LANDUZZI, C. D'ADDARIO, G. LOPETUSO, S. CANDELETTI, P. ROMUALDI, Alterations in prodynorphin gene expression in 6-OHDA lesioned rat brain. XIV SINPF Bologna, June 1-4, 2004, p.19. AWARD
106. D. LANDUZZI, S. CANDELETTI, P. ROMUALDI. Regulation of NOP receptor density by delta-9-tetrahydrocannabinol treatment in SH-SY5Y cells. ICRS, 14th annual symposium on the cannabinoid, Paestum, June 22-27 2004, p.232.
107. LANDUZZI D., CANDELETTI S., ROMUALDI P. Modulation of nociceptin/NOP system by delta9-THC in SH-SY5Y cell line, Second European workshop on cannabinoid research, Busto Arsizio (Varese, Italy), 29-30 Aprile, 2005, p. 77.
108. LANDUZZI D., CANDELETTI S., ROMUALDI P., Delta9-tetrahydrocannabinol down regualtes NOP receptor gene expression in SH-SY5Y cells, 32° Congresso Nazionale della Società Italiana di Farmacologia, Napoli, 1-4 giugno 2005, p.142.
109. Di Benedetto M., D'Addario C., Candeletti S., Romualdi P ROLE OF DIFFERENT NEUROTRANSMITTERS ON COCAINE-MEDIATED EFFECTS ON PRODYNORPHIN GENE EXPRESSION AND CREB ACTIVATION IN THE RAT BRAIN. , 32° Congresso Nazionale della Società Italiana di Farmacologia, Napoli, 1-4 giugno 2005, p.144.
110. DI BENEDETTO M., D'ADDARIO C., CANDELETTI S., ROMUALDI P Possibile role of NOCICEPTIN/OFQ-NOP system in experimental models of Parkinson disease, 32° Congresso Nazionale della Società Italiana di Farmacologia, Napoli, 1-4 giugno 2005, p.142.
111. D'ADDARIO C., DI BENEDETTO M., CANDELETTI S., ROMUALDI P., INVOLVEMENT OF SEROTONIN IN DYNORPHINERGIC SYSTEM REGULATION BY KAPPA-OPIOID AGONIST AND COCAINE TREATMENTS, 32° Congresso Nazionale della Società Italiana di Farmacologia, Napoli, 1-4 giugno 2005,p.182.
112. LANDUZZI D., CANDELETTI S., ROMUALDI P., Cocaine affects NOP receptor gene expression in SH-SY5Y cells, XI Convegno Monotematico SIF Neurofarmacologia e Neurobiologia delle Dipendenze, Bologna 9 settembre 2005, p. 37.
113. LANDUZZI D., CANDELETTI S., ROMUALDI P., Cross-talk between CB1 and NOP receptors in human neuroblastoma SH-SY5Y cells XI Convegno Monotematico SIF Neurofarmacologia e Neurobiologia delle Dipendenze, Bologna 9 settembre 2005, p. 38.
114. Di Benedetto M., D'Addario C., Candeletti S., Romualdi P.EFFECTS OF 3,4-METHYLENDIOXY-N-METHYLAMPHETAMINE (MDMA, 'ECSTASY') ADMINISTRATION ON THE DYNORPHINERGIC SYSTEM IN THE RAT BRAIN. XI Convegno Monotematico SIF Neurofarmacologia e Neurobiologia delle Dipendenze, Bologna 9 settembre 2005, p. 45.
115. D'ADDARIO C., DRGON T, ROMUALDI P. AND UHL GR.Linkage disequilibrium and haplotype analysis of polymorphisms in the GABA receptor cluster on chromosome 4: association study. XI Convegno Monotematico SIF Neurofarmacologia e Neurobiologia delle Dipendenze, Bologna 9 settembre 2005, p.43.
116. LOPETUSO G., ROMUALDI P., CANDELETTI S., NOP receptor density is reduced by chronic infusion with buprenorphine in selected rat brain areas, XI Convegno Monotematico SIF Neurofarmacologia e Neurobiologia delle Dipendenze, Bologna 9 settembre 2005, p. 25.
117. LOPETUSO G., LANDUZZI D., CANDELETTI S., ROMUALDI P., Different impact of chronic tramadol or morphine on prodynorphin gene expression, XI Convegno Monotematico SIF Neurofarmacologia e Neurobiologia delle Dipendenze, Bologna 9 settembre 2005, p. 30.
118. ROMUALDI P., Gli oppiacei nel trattamento farmacologico del dolore da cancro: recenti acquisizioni di farmacogenetica. XIII Congr. Naz. Di Cure Palliative, Bologna, 26 Aprile 2006.
119. ROMUALDI P., The Pharmacology of Opiates, ABCDE Meeting, Bologna 6 June, 2006.
120. Di Benedetto M, D'Addario C., Candeletti S., Romualdi P, Role of CREB in the prodynorphin gene expression regulation by MDMA, Int. Narcotic Research Conference, Berlin 8-13 July 2007, Abst. 233.
121. Di Benedetto M, Porticella E., D'Addario C., Candeletti S., Romualdi P,. Role of CREB in the prodynorphin gene expression regulation by MDMA, 33° Congresso nazionale della SIF, Cagliari, 6-9 Giugno 2007, p. 171
122. D´Addario C, Di Benedetto M, Candeletti S, Romualdi P., The k-opioid receptor agonist U-69593 prevents cocaine-induced DARPP-32 phosphorylation at the P34 in the rat brain, 33° Congresso nazionale della SIF, Cagliari, 6-9 Giugno 2007, p. 167
123. Lopetuso G., Romualdi P., Candeletti S., Detection and quantification of endogenous N/OFQ in the rat cerebrospinal fluid under basal and stimulated conditions. 33° Congresso nazionale della SIF, Cagliari, 6-9 Giugno 2007, p.128.
124. Ruggeri V., Sandrini M., Vitale G., Filaferro M., Pini L.A., Cavina C., Romualdi P., Candeletti S., Possible role for serotonin in the nociceptin/orphanin FQ inhibition of paracetamol-induced antinociception in the rat. European Opioid Conference (EOC) European Neuropeptide Club (ENC), Ferrara, 8-11 Aprile 2008, p.64.
125. Cavina C., Di Benedetto M., D'Addario C., Izenwasser S., Candeletti S., Romualdi P., Chronic cocaine induces alterations of N/OFQ-NOP system gene expression in the rat brain. European Opioid Conference (EOC) European Neuropeptide Club (ENC), Ferrara, 8-11 Aprile 2008, p.57.
126. D'Addario C, Vukojevic V, Ekstrom T, Romualdi P, Ogren SO, Terenius L. A new approach to study alcoholism: molecular imaging and epigenetic analysis of ethanol dependence mechanisms. 3rd International Forum Innovation in Psychiatry. November 18-20th 2009, Milan. AWARD
127. D'Addario C, Candeletti S, Romualdi P. Basal expression of endogenous opioid genes in mice neuronal tissues involved in pain control. 34° Congresso Nazionale della Società Italiana di Farmacologia, Rimini, 14-17 Ottobre 2009. P 1/5/1
128. D'Addario C, Caputi FF, Candeletti S, Romualdi P., Vukojevic V, Ogren SO, Terenius L. New Insight for a therapeutical approach to alcoholism: study of toxicity, tolerance and ethanol dependence mechanisms by regulation of transcription, molecular imaging, and epigenetic analysis. 34° Congresso Nazionale della Società Italiana di Farmacologia, Rimini, 14-17 Ottobre 2009. C 2/6/6
129. D'Addario C, Ekstrom TJ, Ogren SO, Romualdi P, Terenius L. Prodynorphin gene regulation by epigenetic mechanisms following ethanol and acetaldehyde exposure in SH-SY5Y cells. 22nd European College of Neuropsychopharmacology Congress, 12-16 September 2009, Istanbul P6 b 008. AWARD
130. D'Addario C, Caputi FF, Candeletti S, Rimondini R, Romualdi P. Epigenetic insight for mechanisms of opioid gene regulation induced by alcohol. XVII Congresso Nazionale della Società Italiana di NeuroPsicoFarmacologia Cagliari, 22-25 settembre 2010, P79 page 110.
131. D'Addario C, Dell'Osso B, Cattaneo E, Palazzo M, Galimberti D, Fenoglio C, Scarpini E, Arosio B, Bergamaschini L, Candeletti S, Romualdi P, Altamura AC. DNA hypermethylation of BDNF promoter in patients with bipolar disorder type II XVII Congresso Nazionale della Società Italiana di NeuroPsicoFarmacologia Cagliari, 22-25 settembre 2010, P17 page 82 AWARD
132. D'Addario C, Caputi FF, Candeletti S, Rimondini R, Romualdi P. Alcohol exposures induce selective alterations on endogenous opioid system genes regulation in rat amygdala: possible epigenetic mechanisms; 23nd European College of Neuropsychopharmacology Congress, 28 Agosto - 1 Settembre 2010, Amsterdam P.6.b.007: AWARD
133. D'Addario C, Dell'Osso B, Galimberti D, Scarpini E, Arosio B, Bergamaschini L, Fenoglio C, Candeletti S, Romualdi P, Altamura AC. Selective DNA methylation of BDNF promoter in bipolar disorder; 23nd European College of Neuropsychopharmacology Congress, 28 Agosto - 1 Settembre 2010, Amsterdam P.2.f.002.
134. D'Addario C, Caputi FF, Candeletti S, Romualdi P Different Alcohol exposures induce selective alterations on the expression of the endogenous opioid system genes: possible epigenetic mechanisms; WorldPharma 2010 17-23 July, 2010, Copenaghen AWARD
135. D'Addario C, Caputi FF, Candeletti S, Rimondini R, Romualdi P. Alcohol exposure induce selective alterations on endogenous opioid system genes regulation in rat amygdala:possible epigenetic mechanisms. INRC 2010 Malmö, Sweden July 11-16, 2010N 29, pp 87.
136. S. Bastias Candia, C. Abbate, A. Casè, C. D'Addario, S. Candeletti, P. Romualdi, B. Arosio, C. Vergani, L. Bergamaschini; Valutazione dell'espressione di geni selezionati in una coppia di gemellli omozigoti discordanti per la malattia di Alzheimer, 55° Congresso Nazionale SIG Florence (Italy) 2010.
137. M. Di Benedetto, S. Bastías Candia, C. D'Addario, S. Candeletti, P. Romualdi. 3,4-methylenedioxymethamphetamine (MDMA) regulates opioid gene expression in the rat brainstem through the involvement of serotonin and the activation of CREB and ERK cascade 35° Congresso Nazionale della Società Italiana di Farmacologia, Bologna, 14-17 Settembre 2011. PREMIO
138. D. Mercatelli, M. Di Benedetto, C. D'Addario, M. Canossa, P. Romualdi, S. Candeletti. Neuropeptidergic systems and neuropathic pain: insights from gene expression and epigenetics. 35° Congresso Nazionale della Società Italiana di Farmacologia, Bologna, 14-17 Settembre 2011. AWARD
Pubblicazioni
139. Di Benedetto M, D'Addario C, Dell'Osso B, Bastias Candia S, Cortini F, Galimberti D, Scarpini E, Candeletti S, Altamura A, Romualdi P; Investigation on DNA methylayion status of opioid peptides promoters in PBMCs of subjects with bipolar disorder, 8th Meeting of the European Opioid Conference, Krakow (Poland) April 13-15, 2011.
140. Bastia Candia S., Di Benedetto, D'Addario, Candeletti S and Romualdi P. Role of nociceptin(orphaninFQ system in paraquat and maneb animal model of Parkinson's disease, IBRO Congress, Florence (Italy) July 2011.
141. D. Mercatelli, D. Carretta,, FF. Caputi, P Romualdi, S Candeletti Pronociceptin gene expression changes at different levels of the neuraxis in a murine model of neuropathic pain. 14th World Congress on Pain, Milan (Italy), August 27-31, 2012.
142. D. Mercatelli, D. Carretta, P. Romualdi, S. Candeletti Alterations of neuropeptidergic systems in neuropathic pain conditions: epigenetic and gene expression changes, 2012 Monothematic Congress SIF La ricerca Farmacologica sul Dolore: dai modelli comportamentali all'epigenetica, Nov 29-30, Bologna, Italy.
143. Caputi F.F., Buccellato E., Carretta D., Mercatelli D., Speroni E., Candeletti S., Romualdi P. Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis Monothematic Congress SIF Ferrara (Italy), September 14-15, 2012.
144. Caputi F.F., Carretta D., Candeletti S., Romualdi P. MOP and NOP gene expression changes in SH-SY5Y cells following different schedules of Tapentadol exposures. Monothematic Congress SIF, Bologna (Italy), 29-30 November, 2012.
145. Lattanzio F., Caputi F.F., Carretta D., Mercatelli D., Candeletti S., Romualdi P. Morphine and Fentanyl effects on NOP and MOP gene expression in human neuroblastoma SH-SY5Y cells. Monothematic Congress SIF, Bologna (Italy), 29-30 November, 2012.
146. Caputi F.F., Carretta D., Candeletti S., Romualdi P. Epigenetic mechanisms underlie changes of dynorphin and nociceptin gene expression in rat striatum following cocaine exposure. EOC 2013, Guildford (UK), 10-12 April 2013.
147. F. Lattanzio, L. Carboni, R. Rimondini, D. Carretta, S. Candeletti, D. Mercatelli and P. Romualdi. Pin1 gene expression changes in Alzheimer's disease models: in vitro and in vivo studies. Poster. 11th International Conference On Alzheimer's and Parkinson's Diseases. March 6-10, 2013. Florence, Italy.
148. Caputi F.F., Di Benedetto M., Carretta D., Candeletti S., Romualdi P. How does MDMA (Ecstasy) affect the Endogenous Opioid System? XXXVI SIF , Torino (Italy) October 23-26, 2013.
149. Caputi F.F., Lattanzio F., Carretta D., Candeletti S., Romualdi P. Paraquat and maneb differently affect opioid receptor gene expression in human neuroblastoma SH-SY5Y cells XXXVI SIF, Torino (Italy) October 23-26, 2013.
Pubblicazioni
150. Caputi F.F., Palmisano M., Carretta D., Carboni L., Candeletti S., Romualdi P. Chromatin remodeling in the Endogenous Opioid System induced by MDMA GdL SIF Verona (Italy) November 28-29, 2013.
151. Caputi F.F., Carboni L., Candeletti S., Romualdi P. Could the UPS-complex be a new target in addiction disease? GdL SIF Verona (Italy) November 28-29, 2013.
152. Caputi F.F., D’ Addario C., Canossa M., Carboni L., Carretta D., Candeletti S., Romualdi P. proDynorphin gene expression after acute ethanol exposure in Wild-Type and BDNF+/- mice. In-BDNF Conference Imola (Italy) November 29-30, 2013.
153. Mercatelli D., Palmisano M., Caputi F.F., Romualdi P., Candeletti S. Nociceptin-NOPr system alterations in mood/pain related brain areas. Mood Disorders: From Neurobiology To Novel Therapeutic Strategies, Monothematic Congress SIF, March 20-21, 2014 Modena, Italy.
154. Palmisano M., Carboni L.; Caputi F.F., Candeletti S., Romualdi P. Chronic bupropion treatment regulates prodynorphin gene expression in rat brain regions. Mood Disorders: From Neurobiology To Novel Therapeutic Strategies, Monothematic Congress SIF, Modena, Italy.March 20-21, 2014.
155.Lattanzio F., Carboni L., Rimondini R., Carretta D., Candeletti S., Mercatelli D.,Romualdi P. Sirt1 and Pin1 involvement in Alzheimer's disease pathogenesis: in vitro and in vivo studies. 9th Fens Forum of Neuroscience. Milan, Italy, July 5-9, 2014.
156.Caputi F.F., Palmisano M., Carboni L., Carretta D., Candeletti S., Romualdi P. "Potential Role Of 26s Proteasome Machinery In The Molecular Mechanisms Of Ethanol and Cocaine Exposure" 9th FENS Forum of Neuroscience, Milan, Italy,July 5-9, 2014.
157.Caputi F.F., Carboni L., Candeletti S., Romualdi P. "The Ubiquitin-26S Proteasome System as a common target for cocaine and ethanol exposure". Monothematic SIF Meeting on Addictive Disorders: From Neurobiology to Novel Therapeutic Strategies, Palermo, Italy,March 27-28, 2015.
158. Palmisano M., Caputi F.F., Candeletti S., Ubaldi M., Ciccocioppo R., Romualdi P. “Innate and ethanol-induced differences in the Extended Amygdala gene expression between Marchigian Sardinian alcohol-preferring (msP) and Wistar rats” Monothematic SIF Meeting on Addictive Disorders: From Neurobiology to Novel Therapeutic Strategies, Palermo (Italy), Oral Comunication, March 27-28, 2015.
159. Domi E., Ciccocioppo R., Scuppa G., Romualdi P., Caputi F.F., Candeletti S., Ubaldi M. “Pioglitazone reduce nicotine withdrawal symptoms through PPARγ stimulation”. Monothematic SIF Meeting on Addictive Disorders: From Neurobiology to Novel Therapeutic Strategies, Palermo (Italy), Oral Comunication, March 27-28, 2015.
160. Caputi F.F., Palmisano M., Mazza D., Romualdi P., Candeletti S. "pN/OFQ gene expression alterations in rat lymphocytes during neuropathic pain". Monothematic SIF Meeting on "Advances in pain research: pathophysiology and new therapeutic strategies" Napoli (Italy), Poster session, 18-19 June 2015.
161. Romualdi P., Caputi F.F., Palmisano M., Candeletti S. "Role of the opioid system in alcohol addiction: recent evidence". XVI Congresso SINS, Cagliari (Italy), Oral Comunication, October 8-11 2015.
162. Caputi F.F., Carboni L., Mazza D., Palmisano M., Candeletti S., Romualdi P. "The ubiquitination machinery as a new target of cocaine and ethanol effects: gene expression and activity alterations of the 26S proteasome in neuroblastoma cells". XXXVII Congresso Nazionale SIF, Napoli(Italy), Poster session, October 26-30, 2015.
163. Caputi F.F., Palmisano M., Caffino L., Giannotti G., Racagni G., Candeletti S., Fumagalli F., Romualdi P. "Nociceptin and dynorphin systems alterations in rats chronically exposed to cocaine during adolescence". XXXVII Congresso Nazionale SIF, Napoli(Italy), Poster session, October 26-30, 2015.
164. Palmisano M., Caputi F.F., Candeletti S., Ubaldi M., Ciccocioppo R., Romualdi P. "Marchigian Sardinian alcohol-preferring (msP) and Wistar rats exhibit dynorphin system gene expression differences in response to voluntary ethanol intake in the Extended Amygdala". XXXVII Congresso Nazionale SIF, Napoli (Italy), Poster session, October 26-30, 2015.
165. Caputi F.F., Palmisano M., Mazza D., Candeletti S., Acquas E., Kasture S., Ruiu S., Romualdi P. "The Withania Somnifera root extract, that modifies the morphine analgesic profile, differently affects MOP and NOP gene expression regulation in neuroblastoma SH-SY5Y cells". XXXVII Congresso Nazionale SIF, Napoli (Italy), Oral Comunication, October 26-30, 2015.
166 F.F. Caputi, C. Nasuti, M. Ubaldi, S. Candeletti, R. Ciccocioppo, P. Romualdi. Opioid system gene expression alterations following poly addictive substance exposure in the amygdala of msP rats: ethanol and 3,4-methylenedioxymethamphetamine (MDMA) effects. 19° Seminario SIF. Dottorandi, Assegnisti di Ricerca, Postdottorandi e Specializzandi. Rimini, 20-22 Settembre 2016.
167 .Caputi F.F., Rullo L., Candeletti S., Romualdi P. "Illicit drugs affect the steady-state of chromatin: involvement of the opioid systems in brain reward circuitry". FaBiT Retrit. Poster session February 7-8 2017, Bologna.
168.Palmisano M., Rullo L., Caputi F.F., Romualdi P. and Candeletti S. "Corticostriatal alterations of dynorphin system and bdnf in neuropathic pain condition". Poster session. FaBiT Retrit February 7-8 7 2017, Bologna.
169.Caputi F.F., Rullo L., Di Cesare Mannelli L.,Ghelardini C., Candeletti S. and Romualdi P. "Protesomeimplication in oxaliplatin-inducedneuropathy". ConvegnoMonotematico SIF: The pharmacological basis of novel pain therapeutics. Oral Comunication. Florence, May 4-5 2017.
170.Caputi F.F., Rullo L., Romualdi P. and Candeletti S. "Central dynorphin and nociceptin system alterations in fabry disease-related neuropathy". Convegno Monotematico SIF: The phaarmacological basis of novel pain therapeutics. Poster session. Florence, May 4-5 2017.
171 .Rullo L., Palmisano M., Caputi F.F.,Romualdi P. and Candeletti S. "Corticostriatal alterations of dynorphin system and bdnf in neuropathic pain condition". ConvegnoMonotematico SIF: The pharmacological basis of novel pain therapeutics. Poster session. Florence, May 4-5 2017.
172.Caputi F.F., Sanzio Candeletti, Patrizia Romualdi. "Involvement of proteasome machinery in pain and addiction". 6th Mediterranean Neuroscience Society Conference (MNS) 2017. Oral Symposia, Malta June 12–15, 2017.
173. Romualdi P. , Rullo L., Caputi F.F., Candeletti S. "La ricerca dei nuovi target farmacologici nel trattamento del dolore neuropatico e alimenti a fini medici speciali: quali evidenze scientifiche?" Oral Symposia, FederDolore Cagliari, June 28- 30, 2017.
174. F.F. Caputi, M. Palmisano, L. Rullo, M. Ubaldi, S. Candeletti, R. Ciccocioppo, P. Romualdi."N/OFQ and CRF systems dysregulation in Marchigian Sardinian (msP) rats underlies their innate sensitivity to stress and alcohol preference". Oral Comunication. XXXVIII Congresso Nazionale SIF, Rimini (Italy), , October 25-28, 2017.
175. F.F. Caputi, L. Rullo, S. Candeletti, P. Romualdi. "Addictive drugs and epigenetic regulation at opioid gene promoters in the rat brain reward circuitry". Oral Symposia, XXXVIII Congresso Nazionale SIF, Rimini (Italy), October 25-28, 2017.
176. L. Rullo, F.F. Caputi, P. Romualdi, S. Candeletti. "Selective dynorphin and nociceptin system alterations in the alpha-galactosidase A deficient mouse model of Fabry disease". Poster Contribution, XXXVIII Congresso Nazionale SIF, Rimini (Italy), October 25-28, 2017.
177. L. Rullo, F.F. Caputi, S. Stamatakos , E. Acquas , S. Candeletti , P. Romualdi. “L'estratto standardizzato di radice di Withania somnifera Dunal induce alterazioni dell'espressione genica dei recettori oppioidi e modifica gli effetti indotti dalla morfina”. XVIII Congresso Nazionale SITOX (Bologna) Sessione Poster, 10-13 April 2018.
178. P. Romualdi, L. Rullo, F.F Caputi, S. Stamatakos, S. Candeletti. “Coinvolgimento dell’espressione genica dei recettori oppioidi nella neurotossicità indotta da MDMA”. XVIII Congresso Nazionale SITOX (Bologna) Simposio, 10-13 April 2018.
179 Caputi F.F., Rullo L., Stamatakos S., Stopponi S., Ubaldi M., Candeletti S., Ciccocioppo R., Romualdi P. “ “Epigenetic correlates in addiction neuroplasticity: innate and alcohol- evoked HDACs differences in amygdaloid structures of alcohol preferring (msP) rats”. Convegno Monotematico SIF “ Inside the addicted brain: understanding the neurobiology to program the intervention”, Sessione Poster, Varese 31/05 – 01/06 2018.
180. Rullo L. Caputi F.F., Costa G., Stamatakos S., Candeletti S., Morelli M., Romualdi P. “Acute MDMA intoxication damages the striatal antioxidant activity in male and female young mice” . Convegno Monotematico SIF “ Inside the addicted brain: understanding the neurobiology to program the intervention” , Oral communication, Varese dal 31/05/2018 – 01/06/2018.
181. Costa G., Simola N., Caputi F.F., Rullo L., Candeletti S., Romualdi P., Morelli M. “Mechanisms and neurostransmitter systems involved in the neurotoxic effects of MDMA administration during adolescence”. FENS Satellite Symposium “Mechanisms of Neurodegeneration and Progression” MENEDPRO III. Berlino, Germany, 11-12 July 2018.
182. L. Rullo L, F. F. Caputi, M. Caprini, P. Romualdi and S. Candeletti. Cerebral gene expression alterations in the α-galactosidase A deficient mouse: likely correlations with the neurological hallmarks of Fabry disease. XXI SIF seminar on pharmacology for phd students, fellows, post doc and specialist trainees. Sessione Poster, Bresso (MI), 19-22 September 2018.
183. Rullo L., Caputi FF, Stamatakos S., Candeletti S., Romualdi P. Modulazione esercitata dalla withania somnifera dunal a carico degli effetti della morfina: coinvolgimento di recettori oppioidi e del PPARγ. XXVII Congresso Nazionale della Società italiana di Fitoterapia (SiFIT). Oral Contribution, Reggio Emilia, 24-26 Maggio 2019.
184. Stamatakos S., Caputi F.F., Rullo L., Candeletti S., and Romualdi P. Alterations of BDNF and class I HDAC enzymes induced by repeated MDMA (“ecstasy”) exposure could favour the onset of psychiatric disorders. 1th International ConferencePerinatal Origins of Neuropsychiatric Disorders: from Molecular Mechanisms to Therapeutic Perspectives. Oral Session Palermo, Italy, May 29 – 1 Jun, 2019.
185. Rullo L., Caputi F.F., Costa G., Stamatakos S., Simola N., Candeletti S., Morelli M. and Romualdi P. Striatal antioxidant machinery and nigral dopaminergic neurons after MDMA binge intoxication in the mouse: age and gender influence. 1th International Conference Perinatal Origins of Neuropsychiatric Disorders: from Molecular Mechanisms to Therapeutic Perspectives. Oral Session Palermo, Italy, May 29 – 1 Jun, 2019.
