1) Chemopreventive manipulation of drug metabolizing enzymes by xenobiotics in vivo.
2) Co-toxic, co-mutagenic and co-carcinogenic role of the boosted xenobiotic bioattivation and oxidative
stress linked to P450 superfamily up-regulation.
3) Protective role and development of new (e.g., antioxidants) agents in
chronic-degenerative diseases such as Parkinson's disease,
diabetes, EAE and Alzheimer disease.
