Micucci, Matteo; Battistelli, Michela; Burattini, Sabrina; Osman, Riham; Onesimo, Francesco; Mari, Michele; Retini, Michele; Versari, Ilaria; Pagliarani, Barbara; Tarozzi, Andrea; Zappia, Giovanni; Gianfanti, Federico; Pruccoli, Letizia, Antioxidant and neuroprotective effects of ubiquinol diacetate: Insights from SH-SY5Y cell line and Caenorhabditis elegans models of Parkinson's disease, «EXPERIMENTAL AND MOLECULAR PATHOLOGY», 2026, 145, Article number: 105023 , pp. 1 - 13 [Scientific article]Open Access
Pagliarani, B.; Pruccoli, L.; Chemello, C.; Zusso, M.; Fonseca Moreira, J. C.; Tarozzi, A.; Gomes, H. M., Exploring the anti-inflammatory activity of sulforaphane metabolites, «PHARMACOLOGICAL REPORTS», 2026, 78, pp. 615 - 624 [Scientific article]Open Access
Pagliarani, B.; Mautone Gomes, H.; Pruccoli, L.; Tarozzi, A., Effetti Antiossidanti e Antinfiammatori del Nutraceutico Sulforafano e dei suoi Metaboliti: uno Studio Comparativo in Modelli in vitro, in: Pharmanutrition and Functional Food, 2025, pp. 79 - 79 (atti di: 15° Congresso Nazionale SINut, Bologna, 11-13 settembre 2025) [Abstract]
Pereira, R. M.; Campos, H. M.; De Oliveira Ferreira, P. Y.; Uchenna, N.; Silva, Y. S.; Okoh, V. I.; Pruccoli, L.; Arruda, E. L.; Liao, L. M.; Mota, P. A. A.; Leite, J. A.; De Castro Georg, R.; Damatta, D.; Dos Santos, F. C. A.; Costa, E. A.; Tarozzi, A.; Menegatti, R.; Ghedini, P. C., Glycosylation of chrysin with β-d-glucose tetraacetate (LQFM280) enhances its in vitro and in vivo neuroprotective effects against the toxicity induced by 3-nitropropionic acid, «NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY», 2025, 398, pp. 4095 - 4109 [Scientific article]Open Access
Di Martino, R. M. C.; Russo, D.; Penna, I.; Demuro, S.; Dalle Vedove, A.; Spagnuolo, R.; Ottonello, G.; Bertozzi, S. M.; Summa, M.; Desantis, J.; Valeri, A.; Pruccoli, L.; Tripathi, S. K.; Tarozzi, A.; Storici, P.; Girotto, S.; Bertorelli, R.; Armirotti, A.; Cruciani, G.; Bandiera, T.; Cavalli, A.; Bottegoni, G., Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2025, 297, Article number: 117899 , pp. 1 - 31 [Scientific article]Open Access
Da Fermo, A.; Tarozzi, A.; Pruccoli, L.; Zusso, M.; Orioli, R.; Bisi, A.; Gobbi, S.; Belluti, F., Targeting Alzheimer’s disease neurotoxicity by functionalization
of the chalcone scaffold, in: Poster, 2025(atti di: 29th National Meeting on Medicinal Chemistry (NMMC29) - Parma, Parma, 14-09-2025) [Poster]
Mesquita Campos, Hericles; Mota Pereira, Robbert; Yasmin de Oliveira Ferreira, Pamela; Uchenna, Nkaa; Rio Branco da Silva, Cínthia; Pruccoli, Letizia; Sanz, German; Ferreira Rodrigues, Marcella; Gontijo Vaz, Boniek; Gonçalves Rivello, Barbara; Luís Batista da Rocha, Andre; Silva de Carvalho, Flavio; de Almeida Ribeiro Oliveira, Gerlon; Morais Liao, Luciano; de Castro Georg, Raphaela; Alves Leite, Jacqueline; Cristina Alcantara dos Santos, Fernanda; Alves Costa, Elson; Menegatti, Ricardo; Tarozzi, Andrea; Cesar Ghedini, Paulo, A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models, «CHEMICO-BIOLOGICAL INTERACTIONS», 2024, 395, Article number: 111026 , pp. 1 - 10 [Scientific article]Open Access
Pruccoli, Letizia; Nicolini, Benedetta; Lianza, Mariacaterina; Teti, Gabriella; Falconi, Mirella; Tarozzi, Andrea; Antognoni, Fabiana, Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells, «PLANTS», 2024, 13, Article number: 808 , pp. 1 - 9 [Scientific article]Open Access
Pruccoli, Letizia; Balducci, Martina; Pagliarani, Barbara; Tarozzi, Andrea, Antioxidant and Neuroprotective Effects of Fucoxanthin and Its Metabolite Fucoxanthinol: A Comparative In Vitro Study, «CURRENT ISSUES IN MOLECULAR BIOLOGY», 2024, 46, pp. 5984 - 5998 [Scientific article]Open Access
De Freitas Silva, Matheus; Juliet Cristancho Ortiz, Cindy; Ferreira Coelho, Letícia; Pruccoli, Letizia; Pagliarani, Barbara; Pisani, Leonardo; Catto, Marco; Poli, Giulio; Tuccinardi, Tiziano; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Amaral Alves, Marina; Ribeiro De Souza, Hygor M.; Tarozzi, Andrea; Silva Gontijo, Vanessa; Jr., Claudio Viegas, Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease, «BIOORGANIC CHEMISTRY», 2024, 150, Article number: 107587 , pp. 1 - 18 [Scientific article]Open Access
Balducci M.; Pruccoli L.; Tarozzi A., Heat stress as a potential risk factor for vitamin D deficiency, «MEDICAL HYPOTHESES», 2023, 176, Article number: 111085 , pp. 1 - 3 [Scientific article]Open Access
Zuccarini M.; Pruccoli L.; Balducci M.; Giuliani P.; Caciagli F.; Ciccarelli R.; Di Iorio P., Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions, «JOURNAL OF CLINICAL MEDICINE», 2023, 12, Article number: 1172 , pp. 1 - 17 [Scientific article]Open Access
Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A., PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease, «ACS CHEMICAL NEUROSCIENCE», 2023, 14, pp. 1963 - 1970 [Scientific article]Open Access
De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena, Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 252, Article number: 115297 , pp. 1 - 15 [Scientific article]Open Access
Juliet Cristancho Ortiz, Cindy; De Freitas Silva, Matheus; Pruccoli, Letizia; Fonseca Nadur, Nathália; Luíza De Azevedo, Luciana; Eugen Kümmerle, Arthur; Alvim Guedes, Isabella; Emmanuel Dardenne, Laurent; Felipe Leomil Coelho, Luiz; Guimarães, Marcos J.; Da Silva, Fernanda M. R.; Castro, Newton; Silva Gontijo, Vanessa; Rojas, Viviana C. T.; Ketterym De Oliveira, Merelym; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Barbosa, Gisele; Moreira Lima, Lídia; Beserra Pinheiro, Gabriela; Germino Veras, Letícia; Renata Mortari, Márcia; Tarozzi, Andrea; Viegas Jr, Claudio, Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation, «RSC MEDICINAL CHEMISTRY», 2022, 13, pp. 568 - 584 [Scientific article]Open Access
