Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; Ana Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti, Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease, «ACS CHEMICAL NEUROSCIENCE», 2020, 11, pp. 2728 - 2740 [articolo]Open Access
Maria Rosa Gigliobianco; Barbara Campisi; Dolores Vargas Peregrina; Roberta Censi; Gulzhan Khamitova; Simone Angeloni; Giovanni Caprioli; Marco Zannotti; Stefano Ferraro; Rita Giovannetti; Cristina Angeloni; Giulio Lupidi; Letizia Pruccoli; Andrea Tarozzi; Dario Voinovich; Piera Di Martino, Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach, «ANTIOXIDANTS», 2020, 9, Article number: 370, pp. 1 - 18 [articolo]Open Access
Emanuela Mhillaj, Andrea Tarozzi, Letizia Pruccoli, Vincenzo Cuomo, Luigia Trabace, Cesare Mancuso, Curcumin and Heme Oxygenase: Neuroprotection and Beyond, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2019, 20, Article number: 2419, pp. 1 - 11 [articolo]Open Access
Simona Sestito, Letizia Pruccoli, Massimiliano Runfola, Valentina Citi, Alma Martelli, Giuseppe Saccomanni, Vincenzo Calderone, Andrea Tarozzi, Simona Rapposell, Design and synthesis of H 2 S-donor hybrids: A new treatment for Alzheimer's disease?, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 184, pp. 1 - 11 [articolo]
Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolini M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A., Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 178, pp. 243 - 258 [articolo]Open Access
Morroni F.; Sita G.; Graziosi A.; Ravegnini G.; Molteni R.; Paladini M.S.; Dias K.S.T.; Dos Santos A.F.; Viegas C.; Camps I.; Pruccoli L.; Tarozzi A.; Hrelia P., PQM130, a novel feruloyl-donepezil hybrid compound, effectively ameliorates the cognitive impairments and pathology in a mouse model of Alzheimer's disease, «FRONTIERS IN PHARMACOLOGY», 2019, 10, pp. 1 - 16 [articolo]Open Access
Heider F.; Pantsar T.; Kudolo M.; Ansideri F.; De Simone A.; Pruccoli L.; Schneider T.; Goettert M.I.; Tarozzi A.; Andrisano V.; Laufer S.A.; Koch P., Pyridinylimidazoles as GSK3β Inhibitors: The Impact of Tautomerism on Compound Activity via Water Networks, «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 1407 - 1414 [articolo]
Morroni Fabiana, Sita Giulia, Djemil Alice, D'Amico Massimo, Pruccoli Letizia, Cantelli-Forti Giorgio, Hrelia Patrizia, Tarozzi Andrea., Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson's Disease, «JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY», 2018, 66, pp. 856 - 865 [articolo]Open Access
Dias Viegas, Flávia Pereira; de Freitas Silva, Matheus; Divino da Rocha, Miguel; Castelli, Maísa Rosa; Riquiel, Mariana Máximo; Machado, Rafael Pereira; Vaz, Sarah Macedo; Simões de Lima, Laís Medeiros; Mancini, Karla Cristine; Marques de Oliveira, Patrícia Cruz; Morais, Élida Parreira; Gontijo, Vanessa Silva; da Silva, Fernanda Motta R.; D'Alincourt da Fonseca Peçanha, Dora; Castro, Newton Gonçalves; Neves, Gilda A.; Giusti-Paiva, Alexandre; Vilela, Fabiana Cardoso; Orlandi, Lidiane; Camps, Ihosvany; Veloso, Márcia Paranho; Leomil Coelho, Luis Felipe; Ionta, Marisa; Ferreira-Silva, Guilherme Álvaro; Pereira, Rodrigo Machado; Dardenne, Laurent E.; Guedes, Isabella Alvim; de Oliveira Carneiro Junior, Wellerson; Quaglio Bellozi, Paula Maria; Pinheiro de Oliveira, Antônio Carlos; Ferreira, Fábio Furlan; Pruccoli, Letizia; Tarozzi, Andrea; Viegas, Claudio*, Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2018, 147, pp. 48 - 65 [articolo]Open Access
Rampa, Angela*; Bartolini, Manuela; Pruccoli, Letizia; Naldi, Marina; Iriepa, Isabel; Moraleda, Ignacio; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra, Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease, «MOLECULES», 2018, 23, Article number: 1902, pp. 1 - 22 [articolo]Open Access
de Freitas Silva M, Pruccoli L, Morroni F, Sita G, Seghetti F, Viegas C, Tarozzi A, The Keap1/Nrf2-ARE pathway as a pharmacological target for chalcones, «MOLECULES», 2018, 23, Article number: 1803, pp. 1 - 22 [articolo]Open Access
Rampa, Angela; Montanari, Serena; Pruccoli, Letizia; Bartolini, Manuela; Falchi, Federico; Feoli, Alessandra; Cavalli, Andrea; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra, Chalcone-based carbamates for Alzheimer's disease treatment, «FUTURE MEDICINAL CHEMISTRY», 2017, 9, pp. 749 - 764 [articolo]
Dias, Kris Simone T.; de Paula, Cynthia T.; dos Santos, Thiago; Souza, Isis N.O.; Boni, Marina S.; Guimarães, Marcos J.R.; da Silva, Fernanda M.R.; Castro, Newton G.; Neves, Gilda A.; Veloso, Clarice C.; Coelho, Márcio M.; de Melo, Ivo Souza F.; Giusti, Fabiana C.V.; Giusti-Paiva, Alexandre; da Silva, Marcelo L.; Dardenne, Laurent E.; Guedes, Isabella A.; Pruccoli, Letizia; Morroni, Fabiana; Tarozzi, Andrea; Viegas, Claudio*, Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 130, pp. 440 - 457 [articolo]Open Access
Maestri, Valentina; Tarozzi, Andrea; Simoni, Elena; Cilia, Antonio; Poggesi, Elena; Naldi, Marina; Nicolini, Benedetta; Pruccoli, Letizia; Rosini, Michela; Minarini, Anna, Quinazoline based α1-adrenoreceptor antagonists with potent antiproliferative activity in human prostate cancer cell lines, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 136, pp. 259 - 269 [articolo]
Tarozzi, A; Marchetti, C; Nicolini, B; D'Amico, M; Ticchi, N; Pruccoli, L; Tumiatti, V; Simoni, E; Lodola, A; Mor, M; Milelli, A; Minarini, A., Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate., «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2016, 117, pp. 283 - 291 [articolo]
