Associate Professor at the University of Bologna since 2005, performing research in the field of stem cells. Research works currently focusing on the characterization, differentiation and immunomodulatory activity of mesenchymal stem cells isolated from adipose and perinatal tissues.
Education
Laura BONSI was born in Verona.
-1978: she graduated in Biology in the University of Bologna, discussing the thesis entitled “Agar
cultures of granulocytic stem cells in the study of preleukemic
syndromes”.
Academic Career
-1977-1991 She was Technician of the Institute of Histology, University of Bologna
-1991-2005 General Technician Coordinator.
Since 2005 she is Associate professor of Histology.
She taught “Histology and Embryology " in the specialized degree
course in Medicine and Surgery and in the first level degree
courses in Techniques of Medical Radiology and in Thechniques of
Orthopedics.
From 2005 to 2023 she taught in the specialized degree course in
Medicine and Surgery and in the Master courses of Medical
Biotecnology and Molecular and Industry Biotecnology.
Actually she is Alma Mater Professor and teaches "In vitro biotechnology of human tissues" in the bachelor course "Biotechnology".
Research activity
At the Laboratory of Experimental Hematology directed by she Prof.
Bagnara has dealt with in vitro cultures of hematopoietic
progenitors and stem cell kinetics in response to different growth
factors.
-From October 1983 to November 1984 she worked in the Laboratory
directed by Prof. G. Rovera at "The Wistar Institute" in
Philadelphia (PA-USA) where she developed new techniques for
immunofluorescence cell sorter using monoclonal antibodies directed
against different subsets of stem hematopoietic cells.
From 2000 to the present experimental issues of the research group
directed by her are:
-Gene expression of two growth factors (the Thrombopoietin and
Vascular Endothelium Growth Factor) and their transcripts both in
hematopoiesis and in angio-osteogenesis in patients affected by
congenital preleukemic dysplasias where the biological damage seems
to be ancestral elements such as mesenchymal cells.
-Isolation, characterization and immunomodulatory activity of
mesenchymal stromal cells isolated from sources alternative to bone
marrow such as the dental pulp, adipose tissue and extraembryonic
tissues. This experiment allows the study of the differentiation
potential of stem cells into different "lineages" for a clinical
approach in regenerative medicine.
She collaborates with Start up like Stem Sel and Cell Dynamics on the capabilities of stem cells.
She published 69 papers in National and International journals.
She has been thesis supervisor in the Master courses of Medical
Biotecnology and Molecular and Industry Biotecnology.
