Foto del docente

Ivana Kurelac

Junior assistant professor (fixed-term)

Department of Medical and Surgical Sciences

Academic discipline: MED/03 Medical Genetics

Curriculum vitae

EDUCATION

January 2008-December 2011 PhD student in Human Genetics (Human Oncology program), University of Turin, Italy

October 2001-December 2006 Student of Molecular Biology at the Faculty of Natural Sciences, University of Zagreb, Croatia   

 

TRACK RECORD (February/2018)

34 PubMed Publications, 1 Book chapter, >30 Proceedings (6 as selected or invited speaker), Average impact factor: 5.7, H-index: 14, National qualification for Associate Professor in Medical Genetics

 

EXPERIENCE

Period: 2012-present

Scientific interest: Cancer metabolism - understanding the role of mitochondrial complex I in hypoxic adaptation

Reference contact: Giuseppe Gasparre (giuseppe.gasparre@gmail.com)

 

Period: October 2016-June 2017 and August-December 2018

Scientific interest:The role of stroma and microenvironment in CI deficient tumors

Reference contact:Ilaria Malachi (ilaria.malanchi@crick.ac.uk)

 

Period: April-July 2011

Scientific interest: Genomic profiling of breast, thyroid and pituitary oncocytic neoplasias

Reference contact:J. S. Reis-Filho, Professor of Molecular Pathology (reisfilj@mskcc.org)

Institution: The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research (ICR), London,UK


Period: 2008-2011

Scientific interest: The role of mitochondrial DNA mutations in oxyphilic cancer progression

Reference contact: Giovanni Romeo, Professor of Medical Genetics (egf.giovanni.romeo@gmail.com); Marco Seri, Professor of Medical Genetics (marco.seri@gmail.com)

Institution: Laboratory for Medical Genetics, S. Orsola Hospital, University of Bologna, Bologna, Italy


Period: June-December 2007

Scientific interest: Genetics of Familial and Oxiphilic Thyroid Cancers

Reference contact: Giovanni Romeo, Professor of Medical Genetics (egf.giovanni.romeo@gmail.com)

Institution: Laboratory for Medical Genetics, S. Orsola Hospital, University of Bologna, Bologna, Italy

 

Period: October 2005 - April 2006

Scientific interest: ESTs data base sequencing and expression studies of novel caspases

Reference contact: W.E.G. Muller, Professor of Molecular Biology (wmueller@mail.uni-mainz.de )

Institution: Institut fur Physiologische Chemie, Johannes Gutenberg Universitat, Mainz, Germany

 

AWARDS

2019 PRIN Funding from Italian Ministry of University and Research (MIUR) for the project "MORphological biomarkers For Early diagnosis in Oncology -MORFEO", role: Associated Investigator - Research Unit Leader (107,190.00 euro)

 

2015 The best oral presentation award at The annual meeting of the Italian Group of Biomembranes and Biochemistry (GIBB), Udine, Italy

 

2012 A triennial post-doctoral fellowship from the Italian association for cancer research (AIRC),

assigned for the project “Mitochondrial dysfunction and low-proliferative tumor phenotype” (60,000.00 euro)


 2011 Scholarship from University of Turin (Italy), for visiting Breakthrough Breast Cancer Research Centre (ICR), London, UK (project: "Genomic profiling of thyroid and pituitary neoplasias")


 2010 The best proceeding award at the EMBO Course on Mitochondria and Cancer, Ronzano, Italy


2008 PhD scholarship from Italian Ministry of Education, Universities and Reseach, for entering Human genetics PhD program (Human oncology sector)


 2007 Scholarship from University of Bologna, Bologna, Italy, for “Genetic analysis of familial and

oxyphilic thyroid cancers”


 2005-2006 Scholarship from Johannes Guttenberg University, Mainz, Germany, for “ESTs database

sequencing and expression studies of novel caspases”

 

LANGUAGES

Croatian (mother tongue), English (proficient user), Italian (proficient user), German (independent user)

 

LABORATORY SKILLS

Molecular analyses: PCR based techniques, Sanger sequencing, site directed mutagenesis, HRM, array CGH, LOH and microsatellite analysis, DHPLC, qRT-PCR, Northern blotting, gene cloning, bacterial culture, eukaryote cell culture, Western Blotting, transfection, ZFN/Talen/CrisprCas9 genetic engineering, immunoprecipitation, immunofluorescence, shRNA silencing, in vitro tumorigenic assays, animal handling (xenograft experiments), flow cytometry, immunohistochemistry…

Bioinformatics: Seqscape, GeneMapper, PeakScanner, mutation pathogenicity predictors (Polyphen2, MutPred, …), Clustal X, Primer3,  Oligo Analyzer, RNA structure, Mfold, Webcutter, exome prioritization portals ( Gemapp), FlowJo, DIVA, good knowledge on web databases and portals (STRING, Prosite, KEGG, Ensembl, OMIM, HmtDB, Mitomap, Gene  ontology, ATCC, Geo Data mining, …)

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