Foto del docente

Ivana Kurelac

Senior assistant professor (fixed-term)

Department of Medical and Surgical Sciences

Academic discipline: MED/03 Medical Genetics

Curriculum vitae


January 2008-December 2011 PhD student in Human Genetics (Human Oncology program), University of Turin, Italy

October 2001-December 2006 Student of Molecular Biology at the Faculty of Natural Sciences, University of Zagreb, Croatia   


TRACK RECORD (August/2021)

40  PubMed Publications, 2 Book chapter,s >30 Proceedings (9 as selected or invited speaker), Average impact factor 2020: 6.7, H-index: 19, National qualification for Associate Professor in Medical Genetics



Period: 2012-present

Scientific interest: Cancer metabolism - understanding the role of mitochondrial complex I in hypoxic adaptation

Reference contact: Giuseppe Gasparre (


Period: October 2016-June 2017 and August-December 2018

Scientific interest:The role of stroma and microenvironment in CI deficient tumors

Reference contact:Ilaria Malachi (


Period: April-July 2011

Scientific interest: Genomic profiling of breast, thyroid and pituitary oncocytic neoplasias

Reference contact:J. S. Reis-Filho, Professor of Molecular Pathology (

Institution: The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research (ICR), London,UK

Period: 2008-2011

Scientific interest: The role of mitochondrial DNA mutations in oxyphilic cancer progression

Reference contact: Giovanni Romeo, Professor of Medical Genetics (; Marco Seri, Professor of Medical Genetics (

Institution: Laboratory for Medical Genetics, S. Orsola Hospital, University of Bologna, Bologna, Italy

Period: June-December 2007

Scientific interest: Genetics of Familial and Oxiphilic Thyroid Cancers

Reference contact: Giovanni Romeo, Professor of Medical Genetics (

Institution: Laboratory for Medical Genetics, S. Orsola Hospital, University of Bologna, Bologna, Italy


Period: October 2005 - April 2006

Scientific interest: ESTs data base sequencing and expression studies of novel caspases

Reference contact: W.E.G. Muller, Professor of Molecular Biology ( )

Institution: Institut fur Physiologische Chemie, Johannes Gutenberg Universitat, Mainz, Germany



2020 Funding from Cassa di Risparmio in Bologna (CARISBO) foundation for the project "VAlutazione dell’efficacia della Simultanea inibizione del Complesso I mitocondriale e dei macrofagi tumorali nel trattamento del cancro Ovarico-VASCO", role: Principal Investigator (40,043.20 euro)


2019 PRIN Funding from Italian Ministry of University and Research (MIUR) for the project "MORphological biomarkers For Early diagnosis in Oncology -MORFEO", role: Associated Investigator - Research Unit Leader (107,190.00 euro)


2019 The best oral presentation award at the Italian Society of Molecular biology workshop, Florence, Italy


2015 The best oral presentation award at The annual meeting of the Italian Group of Biomembranes and Biochemistry (GIBB), Udine, Italy


2012 A triennial post-doctoral fellowship from the Italian association for cancer research (AIRC),

assigned for the project “Mitochondrial dysfunction and low-proliferative tumor phenotype” (60,000.00 euro)

 2011 Scholarship from University of Turin (Italy), for visiting Breakthrough Breast Cancer Research Centre (ICR), London, UK (project: "Genomic profiling of thyroid and pituitary neoplasias")

 2010 The best proceeding award at the EMBO Course on Mitochondria and Cancer, Ronzano, Italy

2008 PhD scholarship from Italian Ministry of Education, Universities and Reseach, for entering Human genetics PhD program (Human oncology sector)

 2007 Scholarship from University of Bologna, Bologna, Italy, for “Genetic analysis of familial and

oxyphilic thyroid cancers”

 2005-2006 Scholarship from Johannes Guttenberg University, Mainz, Germany, for “ESTs database

sequencing and expression studies of novel caspases”



Croatian (mother tongue), English (proficient user), Italian (proficient user), German (independent user)



Reviewer:Oncogene, Scientific Reports, British Journal of Cancer, BMC Cancer, Frontiers in Oncology, Cancers (Basel), Journal of Experimental and Clinical Cancer Research, Genes, Frontiers in Pharmacology, Biochimica et Biophysica Acta

Guest Editor: Cancers (Basel) for the 2021 Special Issue on “Tumor microenvironment: a key piece in the puzzle of cancer heterogeneity” (



Molecular analyses: PCR based techniques, Sanger sequencing, site directed mutagenesis, HRM, array CGH, LOH and microsatellite analysis, DHPLC, qRT-PCR, Northern blotting, gene cloning, bacterial culture, eukaryote cell culture, Western Blotting, transfection, ZFN/Talen/CrisprCas9 genetic engineering, immunoprecipitation, immunofluorescence, shRNA silencing, in vitro tumorigenic assays, animal handling (xenograft experiments), flow cytometry, immunohistochemistry…

Bioinformatics: Seqscape, GeneMapper, PeakScanner, mutation pathogenicity predictors (Polyphen2, MutPred, …), Clustal X, Primer3,  Oligo Analyzer, RNA structure, Mfold, Webcutter, exome prioritization portals ( Gemapp), FlowJo, DIVA, good knowledge on web databases and portals (STRING, Prosite, KEGG, Ensembl, OMIM, HmtDB, Mitomap, Gene  ontology, ATCC, Geo Data mining, …)

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