Giulio
Agnetti, PhD: curriculum vitae
DEMOGRAPHIC AND
PERSONAL INFORMATION
Current
Appointment: Assistant Professor
Department of
Biochemistry “G. Moruzzi” – University of Bologna, Italy
Business
Address:
Department of
Biochemistry “G. Moruzzi”
National Institute
for Cardiovascular Research (INRC)
Via Irnerio, 48
40126 Bologna,
Italy
Office:
(01139)0512091226
Fax:
(01139)0512091224
Personal Data:
Status:
unmarried
Place and date of
birth: Como, Italy, 05/07/1975 (MM/DD/YYYY)
PROFESSIONAL
EXPERIENCE
1998-2000 Experimental thesis
internship at the Department of Biochemistry “G. Moruzzi” –
University of Bologna, Italy on “Glucose up-take modulation by
ischemic insult in H9c2 cardiac myoblast”.
2000 (October) Degree in Chemistry
and Pharmaceutical Technologies, University of Bologna, Italy.
2000 (November) Scientific Research
Fellow at the Department of Biochemistry – University of Bologna,
Italy for the study of “Methods for protection of the ischemic
myocardium”.
2001 Admission to the PhD program
in Biochemistry and Pathophysiology of Aging on the “Biomolecular
basis of the transition from cardiac hypertrophy toward
failure”.
2002 Assignment by public interview
of an “Assegno di Ricerca biennale” (biannual contract). Renewed in
2004 and 2006.
2002 (and 2003-2004) Visiting
fellow at the Erasmus MC (Rotterdam, NL) for the “Proteomic study
of an in vitro model for cardiac hypertrophy” (COEUR Institute,
Dept. of Biochemistry, Supervisor Prof. J.M.J. Lamers (6
moths).
2003-2005 Member of the evaluation
board for Biochemistry, Biomedical Engineering program, Faculty of
Engineering, Cesena Campus, Cesena, Italy.
2004 Trainee at the “School of the
Proteome”, supervised by Dr. Luca Bini, Department of Molecular
Biology, University of Siena, Italy (1 week).
2005 (May) PhD in Biochemistry and
Pathophysiology of Aging on “Heart failure as a model of aging:
study of the molecular mechanisms involved in the pathophysiology
of hypertrophy and its transition to failure”.
2005 (August)- Postdoctoral
research fellow at The Hopkins NHLBI Proteomics Center, Johns
Hopkins University, Baltimore, MD, USA.
RESEARCH
ACTIVITIES
1. Agnetti G, Husberg C, Van Eyk JE.
Divide and Conquer:
the Application of Organelle Proteomics to Heart Failure. Invited
Review. Circ Res, in
press.
2. Agnetti G, Kaludercic N, Kane LA,
Elliott ST, Guo Y, Chakir K, Samantapudi D, Paolocci N, Tomaselli
GF, Kass DA, Van Eyk JE.
Modulation of Mitochondrial Proteome and Improved Mitochondrial
Function by Biventricular Pacing of Dyssynchronous Failing Hearts.
Circ Cardiovasc Genet. 2010 Feb 1;3(1):78-87. Epub 2009 Nov
17. PMCID:
PMC2921909.
3. Agnetti
G,
Bezstarosti K, Dekkers DH, Verhoeven AJ, Giordano E, Guarnieri C,
Caldarera CM, Van Eyk JE, Lamers JM. Proteomic profiling of
endothelin-1-stimulated hypertrophic cardiomyocytes reveals the
increase of four different desmin species and alpha-B-crystallin.
Biochim Biophys Acta. 2008 Jul-Aug;1784(7-8):1068-76. Epub 2008 Apr
18. PMCID:
PMC2905868.
4. Agnetti
G,
Kane LA, Guarnieri C, Caldarera CM, Van Eyk JE. Proteomic
technologies in the study of kinases: novel tools for the
investigation of PKC in the heart. Pharmacol Res. 2007
Jun;55(6):511-22. Epub 2007 May 3. Review. PubMed PMID: 17548206;
PubMed Central PMCID: PMC2693016.
5. Kane
LA, Yung CK, Agnetti G,
Neverova I, Van Eyk JE. Optimization of paper bridge loading for
2-DE analysis in the basic pH region: application to the
mitochondrial subproteome. Proteomics. 2006 Nov;6(21):5683-7.
PubMed PMID: 17022103.
6. Faber
MJ, Agnetti G,
Bezstarosti K, Lankhuizen IM, Dalinghaus M, Guarnieri C, Caldarera
CM, Helbing WA, Lamers JM. Recent developments in proteomics:
implications for the study of cardiac hypertrophy and failure. Cell
Biochem Biophys. 2006;44(1):11-29. Review. PubMed PMID:
6456231.
7. Agnetti
G,
Maraldi T, Fiorentini D, Giordano E, Prata C, Hakim G, Muscari C,
Guarnieri C, Caldarera CM. Activation of glucose transport during
simulated ischemia in H9c2 cardiac myoblasts is mediated by protein
kinase C isoforms. Life Sci. 2005 Dec 5;78(3):264-70. Epub 2005 Aug
18. PubMed PMID: 16111715.
8. Agnetti
G,
Bordoni A, Angeloni C, Leoncini E, Guarnieri C, Caldarera CM, Biagi
PL, Hrelia S. Green tea modulation of inducible nitric oxide
synthase in hypoxic/reoxygenated cardiomyocytes. Biochimie. 2005
May;87(5):457-60. PubMed PMID: 15820752.
Research
Support
1. University of Bologna
2. Compagnia di San Paolo, Turin,
Italy
AWARDS
2001 Award for Young Researchers of
the Italian Society for Cardiovascular Research (SIRC), Italy.
2007 Selected speaker at the
American Heart Association Scientific Session, Orlando, FL on
“Effects of Cardiac Resynchronization Therapy on the Mitochondrial
Proteome in a Canine Model Heart Failure”.
2009 Chairman of the section on
“Mitochondria in Cardiac Disease”, ISHR North American Section
meeting, Baltimore, MD.
2009 Finalist of the Functional
Genomics and Translational Biology Young Investigator Award at the
American Heart Association Scientific Session.
2010 Member of the Early Career
Committee of the Council of Functional Genomics and Translational
Biology of the AHA.
2010 Speaker at the annual
scientific retreat of the Department of Medicine at Johns Hopkins
University.
SCIENTIFIC
MEMBERSHIPS
2001 Italian
Society for Cardiovascular Research (SIRC)
2004 International
Society of Heart Research (ISHR)
2005 American Heart
Association (AHA)
2009 Member of the
Eraly Career Committee of the council of Functional Genomics and
Translational Biology of the AHA
2010 Biophysical
Society
PEER REVIEWER
Circulation
Proteomics
Journal of Molecular and Cellular
Cardiology
