Foto del docente

Giulio Agnetti

Assistant professor

Department of Biomedical and Neuromotor Sciences

Academic discipline: BIO/10 Biochemistry

Curriculum vitae

Giulio Agnetti, PhD: curriculum vitae



Current Appointment: Assistant Professor

Department of Biochemistry “G. Moruzzi” – University of Bologna, Italy

Business Address:

Department of Biochemistry “G. Moruzzi”

National Institute for Cardiovascular Research (INRC)

Via Irnerio, 48

40126 Bologna, Italy

Office: (01139)0512091226

Fax: (01139)0512091224

Personal Data:

Status: unmarried

Place and date of birth: Como, Italy, 05/07/1975 (MM/DD/YYYY)




1998-2000 Experimental thesis internship at the Department of Biochemistry “G. Moruzzi” – University of Bologna, Italy on “Glucose up-take modulation by ischemic insult in H9c2 cardiac myoblast”.

2000 (October) Degree in Chemistry and Pharmaceutical Technologies, University of Bologna, Italy.

2000 (November) Scientific Research Fellow at the Department of Biochemistry – University of Bologna, Italy for the study of “Methods for protection of the ischemic myocardium”.

2001 Admission to the PhD program in Biochemistry and Pathophysiology of Aging on the “Biomolecular basis of the transition from cardiac hypertrophy toward failure”.

2002 Assignment by public interview of an “Assegno di Ricerca biennale” (biannual contract). Renewed in 2004 and 2006.

2002 (and 2003-2004) Visiting fellow at the Erasmus MC (Rotterdam, NL) for the “Proteomic study of an in vitro model for cardiac hypertrophy” (COEUR Institute, Dept. of Biochemistry, Supervisor Prof. J.M.J. Lamers (6 moths).

2003-2005 Member of the evaluation board for Biochemistry, Biomedical Engineering program, Faculty of Engineering, Cesena Campus, Cesena, Italy.

2004 Trainee at the “School of the Proteome”, supervised by Dr. Luca Bini, Department of Molecular Biology, University of Siena, Italy (1 week).

2005 (May) PhD in Biochemistry and Pathophysiology of Aging on “Heart failure as a model of aging: study of the molecular mechanisms involved in the pathophysiology of hypertrophy and its transition to failure”.

2005 (August)- Postdoctoral research fellow at The Hopkins NHLBI Proteomics Center, Johns Hopkins University, Baltimore, MD, USA.



1. Agnetti G, Husberg C, Van Eyk JE. Divide and Conquer: the Application of Organelle Proteomics to Heart Failure. Invited Review. Circ Res, in press.

2. Agnetti G, Kaludercic N, Kane LA, Elliott ST, Guo Y, Chakir K, Samantapudi D, Paolocci N, Tomaselli GF, Kass DA, Van Eyk JE. Modulation of Mitochondrial Proteome and Improved Mitochondrial Function by Biventricular Pacing of Dyssynchronous Failing Hearts. Circ Cardiovasc Genet. 2010 Feb 1;3(1):78-87. Epub 2009 Nov 17. PMCID: PMC2921909.

3. Agnetti G, Bezstarosti K, Dekkers DH, Verhoeven AJ, Giordano E, Guarnieri C, Caldarera CM, Van Eyk JE, Lamers JM. Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and alpha-B-crystallin. Biochim Biophys Acta. 2008 Jul-Aug;1784(7-8):1068-76. Epub 2008 Apr 18. PMCID: PMC2905868.

4. Agnetti G, Kane LA, Guarnieri C, Caldarera CM, Van Eyk JE. Proteomic technologies in the study of kinases: novel tools for the investigation of PKC in the heart. Pharmacol Res. 2007 Jun;55(6):511-22. Epub 2007 May 3. Review. PubMed PMID: 17548206; PubMed Central PMCID: PMC2693016.

5. Kane LA, Yung CK, Agnetti G, Neverova I, Van Eyk JE. Optimization of paper bridge loading for 2-DE analysis in the basic pH region: application to the mitochondrial subproteome. Proteomics. 2006 Nov;6(21):5683-7. PubMed PMID: 17022103.

6. Faber MJ, Agnetti G, Bezstarosti K, Lankhuizen IM, Dalinghaus M, Guarnieri C, Caldarera CM, Helbing WA, Lamers JM. Recent developments in proteomics: implications for the study of cardiac hypertrophy and failure. Cell Biochem Biophys. 2006;44(1):11-29. Review. PubMed PMID: 6456231.

7. Agnetti G, Maraldi T, Fiorentini D, Giordano E, Prata C, Hakim G, Muscari C, Guarnieri C, Caldarera CM. Activation of glucose transport during simulated ischemia in H9c2 cardiac myoblasts is mediated by protein kinase C isoforms. Life Sci. 2005 Dec 5;78(3):264-70. Epub 2005 Aug 18. PubMed PMID: 16111715.

8. Agnetti G, Bordoni A, Angeloni C, Leoncini E, Guarnieri C, Caldarera CM, Biagi PL, Hrelia S. Green tea modulation of inducible nitric oxide synthase in hypoxic/reoxygenated cardiomyocytes. Biochimie. 2005 May;87(5):457-60. PubMed PMID: 15820752.



Research Support

1. University of Bologna

2. Compagnia di San Paolo, Turin, Italy



2001 Award for Young Researchers of the Italian Society for Cardiovascular Research (SIRC), Italy.

2007 Selected speaker at the American Heart Association Scientific Session, Orlando, FL on “Effects of Cardiac Resynchronization Therapy on the Mitochondrial Proteome in a Canine Model Heart Failure”.

2009 Chairman of the section on “Mitochondria in Cardiac Disease”, ISHR North American Section meeting, Baltimore, MD.

2009 Finalist of the Functional Genomics and Translational Biology Young Investigator Award at the American Heart Association Scientific Session.

2010 Member of the Early Career Committee of the Council of Functional Genomics and Translational Biology of the AHA.

2010 Speaker at the annual scientific retreat of the Department of Medicine at Johns Hopkins University.



2001 Italian Society for Cardiovascular Research (SIRC)

2004 International Society of Heart Research (ISHR)

2005 American Heart Association (AHA)

2009 Member of the Eraly Career Committee of the council of Functional Genomics and Translational Biology of the AHA

2010 Biophysical Society





Journal of Molecular and Cellular Cardiology

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