Foto del docente

Giulia Miglietta

Junior assistant professor (fixed-term)

Department of Pharmacy and Biotechnology

Academic discipline: BIO/11 Molecular Biology

Publications

Miglietta, Giulia; Marinello, Jessica; Capranico, Giovanni, Immunofluorescence microscopy of G-quadruplexes and R-loops, in: Methods in Enzymology, Orlando, Academic Press, 2024, pp. 1 - 16 (METHODS IN ENZYMOLOGY) [Chapter or essay]

Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.; Pagano B.; Randazzo A.; Amato J.; Capranico G., Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 12055 - 12067 [Scientific article]Open Access

Miglietta G.; Marinello J.; Russo M.; Capranico G., Ligands stimulating antitumour immunity as the next G-quadruplex challenge, «MOLECULAR CANCER», 2022, 21, pp. 180 - 194 [Scientific article]Open Access

Miglietta G.; Russo M.; Duardo R.C.; Capranico G., G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells, «NUCLEIC ACIDS RESEARCH», 2021, 49, pp. 6673 - 6686 [Scientific article]Open Access

Giulia Miglietta; Marco Russo; Giovanni Capranico, G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders, «NUCLEIC ACIDS RESEARCH», 2020, 48, pp. 11942 - 11957 [Scientific article]Open Access

Amato J.; Miglietta G.; Morigi R.; Iaccarino N.; Locatelli A.; Leoni A.; Novellino E.; Pagano B.; Capranico G.; Randazzo A., Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells, «JOURNAL OF MEDICINAL CHEMISTRY», 2020, 63, pp. 3090 - 3103 [Scientific article]Open Access

R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo, Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents, in: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens. 26th - 28th September 2018 - Padova, Italy - Abstract Book, Padova, 2018, pp. 126 - 126 (atti di: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens., Padova, 26-28 settembre 2018) [Abstract]

Cogoi, Susanna; Ferino, Annalisa; Miglietta, Giulia; Pedersen, Erik B; Xodo, Luigi E, The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription, «NUCLEIC ACIDS RESEARCH», 2018, 46, pp. 661 - 676 [Scientific article]

Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander S.; Shchekotikhin, Andrey; Xodo, Luigi E.*, RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation, «JOURNAL OF MEDICINAL CHEMISTRY», 2017, 60, pp. 9448 - 9461 [Scientific article]

Miglietta, Giulia; Cogoi, Susanna; Pedersen, Erik B.; Xodo, Luigi E.*, GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1, «SCIENTIFIC REPORTS», 2015, 5, Article number: 18097 , pp. 18097 - 18097 [Scientific article]

Miglietta, Giulia; Gouda, Alaa S.; Cogoi, Susanna; Pedersen, Erik B.; Xodo, Luigi E.*, Nucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism, «ACS MEDICINAL CHEMISTRY LETTERS», 2015, 6, pp. 1179 - 1183 [Scientific article]

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