Giulia Massaro

Dr. Giulia Massaro

Cardiology Unit. Department of Medical and Surgical Sciences. University of Bologna. Policlinico S.Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.

Tel: +39 0512143598 --- +39 3288337064

Fax: +39 0516364216

giulia.massaro@unibo.it

Sex: Female. Date of birth: 30/03/1986. Nationality: Italian.

Education

Graduation at Faculty of Medicine and Surgery (12/05/2011).

University of Bologna. Policlinico S.Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.

[Prospective evaluation of the QT interval’s alterations in oncological patients under polypharmacological therapy.]

110/110 e lode

Specialization at School of Cardiovascular disease (05/07/2017).

Cardiology Unit. University of Bologna. Policlinico S.Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.

Management of recalled defibrillator leads in clinical practice: results from a patient-tailored approach.

70/70 e lode

Work experience

04/08/2017 – ongoing

Emergency Cardiology Service

Cardiology Unit. University of Bologna.

Policlinico S.Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.

01/09/2017 – 31/10/2018

Research Grant with Clinical Activity about “Complications of cardiac pacing and defibrillation devices”.

Cardiology Unit. Department of Experimental, Diagnostic and Specialty Medicine. University of Bologna.

Policlinico S.Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.

01/11/2018 – ongoing

PhD Programme in Health and Technologies with Clinical Cardiology and Electrophysiology Activity.

Cardiology Unit. Department of Medical and Surgical Sciences. University of Bologna.

Policlinico S.Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.

Recognitions

September 2016: Winner of “Francesco Capestro Award: Electrophysiology &Electrostimulation”

December 2016: Educational Grant SIC Congress 2016

June 2019: Educational Grant Together VT Congress 2019

Co-Investigator in Clinical Studies

• AdaptResponse Clinical Trial (NCT02205359)
• ARITMO project: European Community’s Seventh Framework Programme FP7/2007-2013 under Grant Agreement N°241679
• Bioventrix Revivent TC System Clinical Study (NCT02931240)
• Bioventrix Brave TC Registry
• ETNA-AF-Europe Study (DSE-EDO-04-14-EU)
• RAFFAELLO: Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion (NCT01534962)
• SMART CRT: Strategic Management to Optimize Response To Cardiac Resynchronization Therapy (NCT03089281)
• SOLVE CRT: Stimulation Of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy in Non-Responders and Previously Untreatable Patients (NCT02922036)
• WiCS- LV Post Market Surveillance Registry
• WRAP-IT: World-wide Randomized Antibiotic Envelope Infection Prevention Trial (NCT02277990)

PUBLICATIONS

Abstracts

1. M. Biffi, A. Mazzotti, B. Gardini, V. Mantovani, G. Massaro, M. Ziacchi, M. Salomoni, M. Balbo, F. Bonfatti, G. Boriani. RV threshold behaviour al long term: automatic verification of stimulation warrants superior safety! XIV International Symposium on Progress in Clinical Pacing 2010.
2. M. Biffi, B. Gardini, A. Mazzotti, V. Mantovani, G. Massaro, M. Ziacchi, M. Balbo, F. Bonfatti, M. Salomoni, G. Boriani. Phrenic stimulation threshold and body position: implications for LV pacing output programming. XIV International Symposium on Progress in Clinical Pacing 2010.
3. M. Biffi, A. Mazzotti, B. Gardini, V. Mantovani, G. Massaro, M. Ziacchi, M. Balbo, F. Bonfatti, M. Salomoni, G. Boriani. Automatic capture verification is superior to fixed-output stimulation: enhanced pacemaker longevity over a 10-years follow up. XIV International Symposium on Progress in Clinical Pacing 2010.
4. M. Biffi, B. Gardini, A. Mazzotti, G. Massaro, M. Ziacchi, F. Bonfatti, M. Salomoni, M. Balbo, V. Mantovani, G. Boriani. ICD pricing in the real-life scenario: up-front cost or daily cost? XIV International Symposium on Progress in Clinical Pacing 2010.
5. C. Valzania, M. Ziacchi, I. Diemberger, G. Massaro, C. Martignani, M. Biffi, F. Fallani, G. Gavaruzzi, C. Rapezzi, A. Branzi, G. Boriani. Funzione ventricolare destra a riposo e durante sforzo in pazienti sotto postia terapia elettrica di re sincronizzazione cardiaca: analisi mediante angiocardioscintigrafia. G Ital Cardiol 2011; Vol 12, Suppl 3.
6. A. Mazzotti, I. Diemberger, F. Pegreffi, E. Foschi, G. Belli, C. Martignani, M. Biffi, B. Gardini, G. Massaro, M. Ziacchi, G. Porcellini, C. Tentoni, A. Branzi, G. Boriani. Prospective assessment of the effects of subcutaneous implantation of cardioverter-defibrillator on shoulder function. G Ital Cardiol 2011; Vol 12, Suppl 3.
7. I. Diemberger, I. Corazza, G. Massaro, M. Ziacchi, J. Frisoni, C. Martignani, M. Biffi, R. Zannoli, G. Boriani. Effetti della stimolazione biventricolare sulla circolazione periferica a riposo in pazienti con scompenso cardiaco. G Ital Cardiol 2011; Vol 12, Suppl 3.
8. C. Martignani, A. Corzani, A. Marziali , M. Ziacchi, C. Valzania, A. Mazzotti, G. Massaro, P. Cimaglia, M. Biffi, G. Boriani. Functional and structural reverse cardiac remodelling after typical persistent atrial flutter ablation: echocardiographic insights. ESC Congress 2014.
9. C. Martignani, A. Marziali , A. Corzani, M. Ziacchi, C. Valzania, A. Mazzotti, G. Massaro, P.Cimaglia, M. Biffi, G. Boriani. Variation of maximum p-wave duration and p-wave dispersion: markers of atrial reverse remodeling and predictors of sinus rhythm mainteinance after cavotricuspidal ablation for typical atrial flutter. ESC Congress 2014.
10. I. Diemberger, E. Raffaelli, G. Massaro, E. Zardi, A. Corzani, S. Lorenzetti, R. Narducci, C. Martignani, M. Ziacchi, M. Biffi, G. Boriani. Predictors of long term complications after transvenous lead-extraction for pacemaker/defibrillator infection: a prospective study. ESC Congress 2016.
11. R. Mei, L. Bianchini, C. Martignani, M. Biffi, M. Ziacchi, G. Massaro, S. Lorenzetti, M. Gallucci, J. Frisoni, G. Boriani, I. Diemberger. Atrial fibrillation in cardiology practice: a prospective monocentric registry analysis and a 3-years outcome evaluation related to standard echocardiographic parameters. XVII International Symposium on Progress in Clinical Pacing 2016.
12. I. Diemberger, G. Tanzarella, J. Frisoni, G. Massaro, E. Zardi, S. Lorenzetti, C. Martignani, M. Biffi, M. Ziacchi, G. Boriani. Risk factors for CIED infections and long term outcomes after lead extraction. 78° Congresso Nazionale SIC Rome 2017.
13. G. Massaro, I. Diemberger, G. De Zan, A. Angeletti, S. Lorenzetti, C. Martignani, M. Ziacchi, M. Biffi. Gestione nella pratica clinica degli elettrocateteri da defibrillazione sottoposti a recall: risultati di un approccio individualizzato al paziente. AIAC National Congress 2018.
14. I. Diemberger, M. Ziacchi, C. Martignani, G. Massaro, J. Frisoni, A. Angeletti, S. Lorenzetti, M. Biffi. Low energy testing with implantable subcutaneous defibrillator: efficacy and predictors. AIAC National Congress 2018 Apr.
15. I. Diemberger, S. Lorenzetti, M. Biffi, G. Massaro, M. Ziacchi, C. Martignani, R. Bonfiglioli, G. Tanzarella, E. Zardi, S. Fanti, G. Boriani. Nuclear imaging for defining systemic involvement of CIED infection and prediction of medium term survival. AIAC National Congress 2018.
16. I. Diemberger, S. Lorenzetti, G. Massaro, J. Frisoni, A. Angeletti, C. Martignani, M. Ziacchi, G. Statuto, M. Biffi. Predictors of ghosts after transvenous lead extraction for CIED infection. ESC Congress 2018.
17. G. Massaro, J. Frisoni, S. Lorenzetti, A. Angeletti, G. Statuto, M. Ziacchi, M. Biffi, C. Martignani, I. Diemberger. Terapia con nuovi anticoagulanti orali in paziente sottoposto a trapianto allogenico di cellule staminali emopoietiche per linfoma non-Hodgkin. SIC Congress 2018 Dec.
18. G. Massaro, J. Frisoni, A. Angeletti, S. Lorenzetti, G. Statuto, M. Ziacchi, M. Biffi, C. Martignani, I. Diemberger. Interazione farmacologica tra nuovi anticoagulanti orali e antiaritmici. SIC Congress 2018 Dec.
19. S. Lorenzetti, R. Bonfiglioli, C. Martignani, M. Graziosi, M. Biffi, M. Ziacchi, C.Nanni, G. Massaro, J. Frisoni, S. Fanti, G. Boriani, I. Diemberger. PET imaging adoption for diagnosis of pacemaker or defibrillator related endocarditis: role in prediction of survival after transvenous lead extraction. SIC Congress 2018 Dec.
20. G. B. Forleo, L. Calo, D. Ricciardi, G. Morani, C. Pignalberi, V. Calzolari, M. Giammaria, A. Curnis, E. Bertaglia, V. Ribatti, G. Massaro, M. Potenza, L. Santini, Y. Nabutovsky, F. Zanon. Multipoint pacing reduces heart failure hospitalizations and associated costs: an analysis of the IRON-MPP study. EHRA Congress 2019
21. I. Diemberger, G. Massaro, J. Frisoni, R. Bonfiglioli, R. Mei, S. Lorenzetti, A. Angeletti, G. Statuto, V. Marinelli, F. Sanguettoni, M. Ziacchi, C. Martignani, M. Biffi One year survival after transvenous lead extraction in patients with lead-associated endocarditis: the importance of pocket involvement. EHRA Congress 2019
22. S. Lorenzetti, G. Massaro, A. Angeletti, P. Paolisso, G. Statuto, J. Frisoni, V. Marinelli, F. Sanguettoni, M. Ziacchi, C. Martignani, M. Biff, I. Diemberger. Caratteristiche cliniche associate all’utilizzo di “sheath” potenziati per completare l’estrazione transvenosa di elettrocateteri a causa di infezione di dispositivi cardiaci elettronici impiantabili. AIAC National Congress 2019 Apr.
23. G. Statuto, A. Angeletti, P. Paolisso, G. Massaro, S. Lorenzetti, J. Frisoni, C. Martignani, M. Ziacchi, D. Giacopelli, D. Grassini, I. Diemberger, M. Biffi. Incidenza di aritmie in pazienti portatori di defibrillatore cardiaco impiantabile monocamerale. AIAC National Congress 2019 Apr.
24. P. Paolisso, G. Statuto, A. Angeletti, G. Massaro, S. Lorenzetti, J. Frisoni, C. Martignani, M. Ziacchi, D. Giacopelli, D. Grassini, I. Diemberger, M. Biffi. Rilevamento di fibrillazione atriale in pazienti portatori di defibrillatore. AIAC National Congress 2019 Apr.
25. A. Angeletti, P. Paolisso, G. Statuto, G. Massaro, S. Lorenzetti, J. Frisoni, C. Martignani, M. Ziacchi, D. Giacopelli, D. Grassini, I. Diemberger, M. Biffi. Trattamento delle aritmie ventricolari in portatori di ICD monocamerale: efficacia dell’ATP in una popolazione contemporanea. AIAC National Congress 2019 Apr.

Articles

1. 1. M. Ziacchi, M. Bertini, M. Biffi, C. Martignani, I. Diemberger, E. Cervi, C. Valzania, A. Mazzotti, B. Gardini, G. Massaro, C. Moschini, V. Mantovani, A. Marziali, G. Boriani. L’ottimizzazione degli intervalli AV e VV nei pazienti con device biventricolare: revisione della letteratura e contributo sperimentale. GIAC Vol. 13, Num. 3-4, settembre-dicembre 2010.
   2. M. Biffi, M. Ziacchi, M. Bertini, D. Corsini, B. Gardini, A. Mazzotti, G. Massaro, C. Martignani, I. Diemberger, G. Boriani. How to truly value ICD technology: up-front cost or daily cost? Int J Technol Assess Health Care 2011 Jul;27(3):201-6.
   3. G. Boriani, E. Cervi, G. Massaro, I. Diemberger, M. Ziacchi, V. Mantovani, A. Marziali, C. Martignani, M. Biffi, M. Ongari, A. Branzi. Dall’ipertensione alla fibrillazione atriale: quali novità? Atti del 45° Convegno Internazionale, Dipartimento Cardiotoracovascolare “A. De Gasperis” - Azienda Ospedaliera Ospedale Niguarda Ca’ Granda Milano, Sep 2011.
   4. M. Biffi, M. Bertini, M. Ziacchi, B. Gardini, A. Mazzotti, G. Massaro, I. Diemberger, C. Martignani, C. Valzania, G. Boriani. Management of Phrenic Stimulation in CRT Patients over the Long Term: Still an Unmet Need? Pacing Clin Electrophysiol 2011 Oct;34(10):1201-8.
   5. I. Diemberger, A. Mazzotti, G. Massaro, C. Martignani, M. Ziacchi, L. Bacchi Reggiani, P. Battistini, G. Boriani. From lead management to implanted patient management: systematic review and meta-analysis of the last 15 years of experience in lead extraction. Expert Rev Med Devices 2013 Jul;10(4):551-73.
   6. I. Diemberger, G. Massaro, M. Cubelli, D. Rubino, S. Quercia, C. Martignani, M. Ziacchi, M. Biffi M, A. Bernardi, N. Cacciari, C. Zamagni, G. Boriani. Repolarization effects of multiple-cycle chemotherapy and predictors of QTc prolongation: a prospective female cohort study on >2000 ECGs. Eur J Clin Pharmacol 2015 Aug;71(8):1001-9.
   7. M. Ziacchi, D. Saporito, D, M. Zardini, M. Luzi, F. Quartieri, G. Morgagni, E. De Maria, M. Bertini, V. Carinci, G. Boriani, M. Biffi. Left Ventricular Reverse Remodeling Elicited by a Quadripolar Lead: Results from the Multicenter Per4mer Study. Pacing Clin Electrophysiol 2016 Mar;39(3):250-60. (see Appendix)
   8. M. Ziacchi, A. Corzani, I. Diemberger, C. Martignani, A. Marziali, A. Mazzotti, G. Massaro, C. Rapezzi, M. Biffi, G. Boriani. Electrocardiographic Eligibility for Subcutaneous Implantable Cardioverter Defibrillator Evaluation during Bicycle Exercise? Heart, Lung and Circulation 2016 May; 25(5):476–83.
   9. I. Diemberger, G. Massaro, M. L. Bacchi Reggiani, S. Lorenzetti, M. Biffi, M. Ziacchi, C. Martignani, G. Boriani. Outcomes with dronedarone in atrial fibrillation: what differences betweene real-world practice and trials? A meta-analysis and meta-regressiona analysis. Curr Pharm Des. 2017;23(6):944-951.
   10. M. Biffi, G. Massaro, I. Diemberger, C. Martignani, A. Corzani, M. Ziacchi. Cardiac resynchronization therapy in persistent left superior vena cava: Can you do it two-leads-only? HeartRhythm Case Rep 2016 Oct;3(1):30-32.
   11. M. Biffi, A. Candelora, G. Massaro. Ventricular Fibrillation Triggered by Earthquake During the Accumoli-Amatrice Disaster in Italy. Circ J 2017 Apr;81(5):759-760.
   12. M. Biffi, G. Massaro, A. Candelora, A. Angeletti, C. Valzania, C. Martignani, D. Grassini, I. Diemberger, M. Ziacchi. Less is more: Can we achieve cardiac resynchronization with 2 leads only? Int J Cardiol. 2017 Dec 15;249:184-190.
   13. I. Diemberger, F. Migliore, M. Biffi, A. Cipriani, E. Bertaglia, S. Lorenzetti, G. Massaro, G. Tanzarella, G. Boriani. The "Subtle" connection between development of cardiac implantable electrical device infection and survival after complete system removal: An observational prospective multicenter study. Int J Cardiol. 2018 Jan 1;250:146-149.
   14. I. Diemberger, E. Fantecchi, M.L. Bacchi Reggiani, C. Martignani, A. Angeletti, G. Massaro, M. Ziacchi,M. Biffi, G.Y.H. Lip, G. Boriani. Atrial fibrillation and prediction of mortality by conventional clinical score systems according to the setting of care. Int J Cardiol. 2018 Jun 15;261:73-77 (Epub 2018 Mar 14).
   15. M. Biffi M, G. De Zan, G. Massaro, A. Angeletti, C. Martignani, G. Boriani, I. Diemberger, M. Ziacchi. Is ventricular sensing always right, when it is left? Clin Cardiol. 2018 Jul 27. doi: 10.1002/clc.23033.
   16. I. Diemberger, S. Genovesi, G. Massaro, ML Bacchi Reggiani, J. Frisoni, G. Gorlato, E. Mauro,M. Padeletti, A. Vincenti, G.Boriani. Meta-analysis of clinical outcomes of electrical cardioversion and catheter ablation in patients with atrial fibrillation and chronic kidney disease. Curr Pharm Des. 2018;24(24):2794-2801.
   17. M. Ziacchi, I. Diemberger, A. Corzani, C. Martignani, A. Mazzotti, G. Massaro, C. Valzania, C. Rapezzi, G. Boriani, M. Biffi. Cardiac resynchronization therapy: a comparison among left ventricular bipolar, quadripolar and active fixation leads. Sci Rep. 2018 Sep 5;8(1):13262.
   18. Biffi M, Ziacchi M, Angeletti A, Castelli A, Massaro G, Martignani C, Lovecchio M, Valsecchi S, Diemberger I. Successful defibrillation verification in subcutaneous implantable cardioverter-defibrillator recipients by low-energy shocks. Clin Cardiol. 2019 Apr 16. doi: 10.1002/clc.23184.