Foto del docente

Giancarlo Solaini

Professor

Department of Biomedical and Neuromotor Sciences

Academic discipline: BIO/10 Biochemistry

Curriculum vitae

NAME:             Solaini, Giancarlo

Scientific curriculum

Position held and professional experience:

1974-1979        Research Fellow, Institute of Biological Chemistry, University of Bologna, Italy (Prof. C.A. Rossi). 

1979-1980        Post-doc Fellow, Dept of Chemistry and Molecular Sciences, University of Warwick, UK (Dr. D.E. Griffiths).

1981-1987        Research Associate, Dept of Biochemistry, University of Bologna, Italy (Prof. C.A. Rossi and G. Lenaz). 

1988-2004        Professor, Associate of Biochemistry, Medical Department, Scuola Superiore di Studi Universitari e di    Perfezionamento  S. Anna, Pisa, Italy

2005-2015         Professor, Associate of Biochemistry, Medical School, University of Bologna, Italy 

2016-               Full Professor of Biochemistry, Medical School, University of Bologna, Italy

1981 & 1982    Visiting research fellow at the Department of Biochemistry, Royal Free Hospital School of Medicine, University of London (UK), collaboration with Prof. Dennis Chapman.   

1993                Guest worker at the Laboratory of Molecular Biology del Medical Research Council di Cambridge (UK), collaboration with Prof Sir John E. Walker (Nobel Laureate, 1997)

1999                Guest worker at the Doheny Eye Institute, Depts of Ophtalmology and Surgery (Neurological), University of Southern California School of Medicine, Los Angeles (USA), collaboration with Prof. A Sadun and Dr. V. Carelli

2001, 2002, 2003, 2004, 2006      Visiting research fellow at the Department of Biochemistry, University of Oxford (UK), collaboration with Dr. David A. Harris.

Main academic and scientific advisory duties: member of the Advisory board of the Department of Biochemistry (1985-88), member of the Management Committee of Scuola Superiore di Studi Universitari e di Perfezionamento S. Anna, Pisa, Italy (1996-2001);  member of the Management Committee of the Italian Group of Bioenergetics and Biomembranes (GIBB) (1997-2001, 2003-07, and 2011-15); GIBB President 2014-15); member of the Management Committee of the Italian Biochemistry and Molecular Biology Society (SIB) (2010-2014).

Reviewer ad hoc for scientific journals, including: Biochimica et Biophysica Acta, FEBS Letters, Journal of Biological Chemistry, Neurology, Pediatric Research, Journal of Controlled Release, International Journal of  Biochemistry and Cell Biology, Biochemistry and Cell Biology, Journal of Translational Medicine, Cell Death & Disease, with expertise in mitochondrial physiopathology and in structure, function and regulation of the ATP synthase complex.

Reviewer for grant assignment: for the Italian MIUR (PRIN and FIRB); AFM (Association Francaise contre les Myopathies); The  Dutch Cancer Society, NL; The National Science Centre, Krakow, Poland.

 

Main teaching experience:

1988-2004        Lecturer of Biochemistry, Scuola Superiore di Studi Universitari e di Perfezionamento S. Anna, Pisa, Italy   

1997-2001        Lecturer of Biochemistry, Faculty of Industrial Chemistry, University of Bologna, Italy

2005-                Lecturer of Biochemistry,  Medical School, University of Bologna, Italy 

                         Lecturer of Biochemistry, Laurea Magistrale in Medical Biotechnology, University of Bologna, Italy 

2011-                Lecturer of Bioenergetics,  Medical School, University of Bologna, Italy 

Research interests in the recent years:

The scientific research covers a number of topics under the general heading of bioenergetics and in particular it focuses on aspects of mitochondrial pathophysiology. Specifically the topics are:

  • The role of the endogenous inhibitor protein of F0F1-ATPase (ATP synthase) in normal and transformed cells
  • The pathogenic mechanisms induced by mutations of the mtDNA
  • The expression, stability and catalytic properties of F0F1-ATPase and Cytochrome c Oxidase in aging and Alzheimer's disease
  • Ischemia and hypoxia in mitochondrial physiology and pathology
  • Cellular bioenergetics and metabolism in normal and cancer cells.

 

  • Autore di oltre 140 pubblicazioni scientifiche, la maggior parte delle quali su riviste internazionali con peer reviewers, e recensite dall'Institute for Scientific Information e dall'Index Medicus. Partecipante attivo ad oltre 150 Congressi nazionali ed internazionali, a molti dei quali e' stato invitato come relatore e/o in qualita' di moderatore di sessione.

 Organization of scientific meetings and/or member of the advisory board:

· Pisa, Italy  24 May 1996  Natl Meeting “Towards an in vivo Biochemistry on the Brainâ€

· Pisa, Italy  23-24 May 1996 Annual Meeting of the Group "Nucleotides and Nucleic Acids" of the Italian Biochemical and Molecular Biology Society

· Pisa, Italy  5 Jun 1998  Annual Meeting of the Region Tosco-Umbro-Marchigiana of the Italian Biochemical and Molecular Biology Society

· Pisa, Italy  24-26 September 1999 Annual Meeting of the Italian Group of Bioenergetics and Biomembranes

· Pisa,  Italy 15-18 March 2003  Workshop “HRT in Climacteric and Ageing Brainâ€

· Pisa, Italy  21-26 August 2004  13th European Bioenergetics Conference

· Bologna, Italy  23-25 May 2005  Workshop “Discovery the MITOCONDRIONâ€

· Moscow, Russian Federation  22-27 July 2006  14th European Bioenergetics Conference 

· Bologna, Italy 18-20 October 2007  Second Natl Meeting  “New Perspectives on Mitochondrial Medicineâ€

· Bari, Italy  20-21 Jun 2008  Annual Meeting of the Italian Group of Bioenergetics and Biomembranes

· Dublin, Ireland   21-26 July 2008  15th European Bioenergetics Conference

· Varsaw, Poland  17-22 July 2010 16th European Bioenergetics Conference

· Freiburg, Germany 15-20 September 2012 17th European Bioenergetics Conference

- Chieti, Italy 26-29 September 2012  56th Annual Meeting of the Italian Biochemical and Molecular Biology Society

- Ferrara, Italy 18-20 Settembre 2013  57th  Annual Meeting of the Italian Biochemical and Molecular Biology Society