Foto del docente

Francesco Rinaldi

Teaching tutor

Department of Pharmacy and Biotechnology

Publications

Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli, A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer, in: EACR 2023: Innovative Cancer Science, 12-15 June 2023, Torino, Italy, FEBS PRESS, 2023, pp. 1 - 597 (atti di: EACR 2023: Innovative Cancer Science, Torino, Italy, 12-15 June 2023) [Poster]

Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A., An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 265, pp. 1 - 20 [Scientific article]

Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A., Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics, in: EMBO Practical Course Integrative modelling of protein interactions, 2023(atti di: EMBO Practical Course Integrative modelling of protein interactions, Izmir, 17/09/2023) [Poster]

Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A., Elucidating the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics, in: Società Chimica Italiana - Divisione di Chimica dei Sistemi Biologici, 2023, pp. 1 - 83 (atti di: Convegno Nazionale della Divisione di Chimica dei Sistemi Biologici, Milano, 27/09/2023) [Abstract]

Rinaldi Francesco, Girotto Stefania, Cavalli Andrea, Elucidating the BRCA2-RAD51 interaction through an integrated structural biophysics approach, in: 4° AIC-BMM, 2023, pp. 1 - 35 (atti di: 4th Meeting of the Biological Macromolecules Section of the Italian Crystallographic Association, Fiesole (FI), 05/06/2023) [Abstract]

Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A., Integration of computational and experimental biophysics reveals novel insights on the BRCA2 - RAD51 interaction, in: EMBO Workshop: Computational structural biology, 2023(atti di: EMBO Workshop: Computational structural biology, Heidelberg, 06/12/2023) [Poster]

Rinaldi F., Schipani F., Balboni B., Catalano F., Marotta R., Myers S. H., Previtali V., Veronesi M., Scietti L., Cecatiello V., Pasqualato S., Ortega J. A., Girotto S., Cavalli A., Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer, «ANGEWANDTE CHEMIE. INTERNATIONAL EDITION», 2023, 1, pp. 1 - 13 [Scientific article]Open Access

Balboni B.; Rinaldi F.; Previtali V.; Ciamarone A.; Girotto S.; Cavalli A., Novel Insights into RAD52’s Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies, «CANCERS», 2023, 15, pp. 1817 - 1818 [Scientific article]Open Access

Samuel Harry Myers , Viola Previtali, Laura Poppi, Francesco Rinaldi, Fabrizio Schipani, Jose Antonio Ortega, Francesca De Franco, Marina Veronesi, Roberto Pellicciari, Marinella Roberti, Stefania Girotto, Giuseppina Di Stefano, Andrea Cavalli, Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach, in: ACS Spring 2022, 2022, pp. 1 - 1 (atti di: ACS Spring 2022, San Diego Convention Center, Room 16A, 20/03/2022) [Abstract]

Previtali V., Myers S. H., Bagnolini G., Poppi L., Rinaldi F., Schipani F., Ortega J. A., De Franco F., Pellicciari R., Girotto S., Oliviero G., Walsh N., Valenti G., Tirelli N., Di Stefano G., Roberti M., Cavalli A., Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer, in: ACS Spring 2022, 2022, pp. 1 - 1 (atti di: ACS Spring 2022, San Diego Convention Center, Room 16A, 20/03/2023) [Abstract]

Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Poppi, Laura; Gennari, Arianna; Rinaldi, Francesco; Armirotti, Andrea; Farabegoli, Fulvia; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Girotto, Stefania; Tirelli, Nicola; Cavalli, Andrea, The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2022, 23, Article number: 8338 , pp. 1 - 14 [Scientific article]Open Access

Rinaldi F., Schipani F., Scietti L., Girotto S, Cavalli A., Unveiling the molecular mechanism of BRCA2-RAD51 interaction to tackle cancer onset, in: EMBO Practical Course "Characterization of macromolecular complexes by integrative structural biology", 2022(atti di: EMBO Practical Course "Characterization of macromolecular complexes by integrative structural biology", Grenoble, 27/05/2022) [Poster]

Hutmacher C.; Volta L.; Rinaldi F.; Murer P.; Myburgh R.; Manz M.G.; Neri D., Development of a novel fully-human anti-CD123 antibody to target acute myeloid leukemia, «LEUKEMIA RESEARCH», 2019, 84, Article number: 106178 , pp. 1 - 9 [Scientific article]

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