Rinaldi, F.; Balboni, B.; Girotto, S.; Cavalli, A., An integrative structural study of RAD52, an emerging target in anticancer drug discovery, in: XXIX National Meeting on Medicinal Chemistry of the Italian Chemistry Society, 2025, pp. 1 - 1 (atti di: XXIX National Meeting on Medicinal Chemistry of the Italian Chemistry Society, Parma, 14/09/2025) [Abstract]
Rinaldi, F.; Balboni, B.; Marotta, R.; Girotto, S.; Cavalli, A., Elucidating RAD52 architecture through an integrated structural biology approach, in: 51st Meeting of the Italian Crystallographic Association, 2025, pp. 1 - 1 (atti di: 51st Meeting of the Italian Crystallographic Association, Firenze, 2-5 September 2025) [Abstract]
Rinaldi, F.; Bresciani, V.; Franco, P.; Bernetti, M.; Langer, J.; Cavalli, A.; Girotto, S., Elucidating the BRCA2-RAD51 interaction through an integrated biophysical and structural biology approach, in: Division of Chemistry of Biological Systems Italian Chemical Society Conference, 2025, pp. 1 - 1 (atti di: Division of Chemistry of Biological Systems Italian Chemical Society Conference, Trieste, 18/06/2025) [Abstract]
Rinaldi, F.; Bresciani, V.; Franco, P.; Veronesi, M.; Bernetti, M.; Masetti, M.; Langer, J.; Cavalli, A.; Girotto, S., Probing the BRC repeats RAD51 interaction by integrating computational and experimental biophysics, in: The 49th FEBS Congress, 2025, pp. 1 - 1 (atti di: The 49th FEBS Congress, Istanbul, 05/07/2025) [Contribution to conference proceedings]
Rinaldi, F.; Bernetti, M.; Bresciani, V.; Veronesi, M.; Masetti, M.; Girotto, S.; Cavalli, A., The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study, in: Mammalian DNA Repair Gordon Research Conference: DNA Repair: Fundamental Mechanisms and Human Biology, 2025(atti di: Mammalian DNA Repair Gordon Research Conference: DNA Repair: Fundamental Mechanisms and Human Biology, Ventura (California), 03/02/2025) [Poster]
Rinaldi, F.; Bernetti, M.; Bresciani, V.; Veronesi, M.; Masetti, M.; Girotto, S.; Cavalli, A., The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study, in: Mammalian DNA Repair Gordon Research Seminar: Unraveling the Intricacies of DNA Repair in the Context of Chromatin and Genome Organization, 2025(atti di: Mammalian DNA Repair Gordon Research Seminar: Unraveling the Intricacies of DNA Repair in the Context of Chromatin and Genome Organization, Ventura (California), 02/02/2025) [Poster]
Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti M., Cavalli A., A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery, in: National Congress of the Italian Chemistry Society 2024, 2024, pp. 1 - 999 (atti di: SCI 2024 Chemistry ELEMENTS OF FUTURE, Milano, 26/08/2024) [Contribution to conference proceedings]
Balboni, Beatrice; Marotta, Roberto; Rinaldi, Francesco; Milordini, Giulia; Varignani, Giulia; Girotto, Stefania; Cavalli, Andrea, An integrative structural study of the human full-length RAD52 at 2.2 Å resolution, «COMMUNICATIONS BIOLOGY», 2024, 7, pp. 1 - 12 [Scientific article]
Bresciani V., Rinaldi F., Bernetti M., Masetti M., Combining computational and experimental methods to characterize the RAD51-BRC repeats interaction, in: THE 4th MASBIC ANNUAL SYMPOSIUM SEPTEMBER 25th - 27th, 2024 Abstracts book, 2024, pp. 1 - 97 (atti di: THE 4th MASBIC ANNUAL SYMPOSIUM, Polytechnic University of Marche, 25/09/2024) [Contribution to conference proceedings]
Bresciani V., Rinaldi F., Bernetti M., Masetti M., Elucidating the RAD51-BRC repeats interaction by integrating computational and experimental approaches, in: Summer School on Biomolecular Simulations 2024, 2024(atti di: Summer School on Biomolecular Simulations 2024, Pula, 16/06/2024) [Poster]
Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; Myers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea, New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives, «JOURNAL OF MEDICINAL CHEMISTRY», 2024, 1, pp. 11488 - 11521 [Scientific article]Open Access
Rinaldi F., Girotto S., Review of: Structure-based approaches in synthetic lethality strategies, «CURRENT OPINION IN STRUCTURAL BIOLOGY», 2024, 1, pp. 1 - 10 [Review]
Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli, A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer, in: EACR 2023: Innovative Cancer Science, 12-15 June 2023, Torino, Italy, FEBS PRESS, 2023, pp. 1 - 597 (atti di: EACR 2023: Innovative Cancer Science, Torino, Italy, 12-15 June 2023) [Poster]
Myers, S. H.; Poppi, L.; Rinaldi, F.; Veronesi, M.; Ciamarone, A.; Previtali, V.; Bagnolini, G.; Schipani, F.; Ortega Martínez, J. A.; Girotto, S.; Di Stefano, G.; Farabegoli, F.; Walsh, N.; De Franco, F.; Roberti, M.; Cavalli, A., An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 265, Article number: 116114 , pp. 1 - 20 [Scientific article]Open Access
Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A., Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics, in: EMBO Practical Course Integrative modelling of protein interactions, 2023(atti di: EMBO Practical Course Integrative modelling of protein interactions, Izmir, 17/09/2023) [Poster]
