Foto del docente

Francesca Massenzio

Junior assistant professor (fixed-term)

Department of Pharmacy and Biotechnology

Academic discipline: BIO/09 Physiology

Publications

Sabrina Petralla, Cristina Parenti, Valentina Ravaioli, Irene Fancello, Francesca Massenzio, Marco Virgili, Barbara Monti, Emiliano Pena-Altamira, Dietary Protein Source Influences Brain Inflammation and Memory in a Male Senescence-Accelerated Mouse Model of Dementia, «MOLECULAR NEUROBIOLOGY», 2021, 58, pp. 1312 - 1329 [Scientific article]

Sabrina Petralla, Francesca De Chirico, Andrea Miti, Ottavia Tartagni, Francesca Massenzio, Eleonora Poeta, Marco Virgili, Giampaolo Zuccheri, Barbara Monti, Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches, «BIOMOLECULES», 2021, 11, pp. 1 - 28 [Scientific article]Open Access

Losurdo, Morris; Pedrazzoli, Matteo; D'Agostino, Claudia; Elia, Chiara A.; Massenzio, Francesca; Lonati, Elena; Mauri, Mario; Rizzi, Laura; Molteni, Laura; Bresciani, Elena; Dander, Erica; D'Amico, Giovanna; Bulbarelli, Alessandra; Torsello, Antonio; Matteoli, Michela; Buffelli, Mario; Coco, Silvia, Intranasal delivery of mesenchymal stem cell‐derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease, «STEM CELLS TRANSLATIONAL MEDICINE», 2020, 9, pp. 1068 - 1084 [Scientific article]

Uliassi, Elisa; Pena-Altamira, Luis Emiliano; Morales, Aixa V.; Massenzio, Francesca; Petralla, Sabrina; Rossi, Michele; Roberti, Marinella; Martinez Gonzalez, Loreto; Martinez, Ana; Monti, Barbara; Bolognesi, Maria Laura*, A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential, «ACS CHEMICAL NEUROSCIENCE», 2019, 10, pp. 279 - 294 [Scientific article]

Petralla S.; Pena-Altamira L.E.; Poeta E.; Massenzio F.; Virgili M.; Barile S.N.; Sbano L.; Profilo E.; Corricelli M.; Danese A.; Giorgi C.; Ostan R.; Capri M.; Pinton P.; Palmieri F.; Lasorsa F.M.; Monti B., Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2019, 20, pp. 4486 - 4514 [Scientific article]Open Access

Romeiro L.A.S.; Da Costa Nunes J.L.; De Oliveira Miranda C.; Simoies Heyn Roth Cardoso G.; De Oliveira A.S.; Gandini A.; Kobrlova T.; Soukup O.; Rossi Michele.; Senger J.; Jung M.; Gervasoni S.; Vistoli G.; Petralla S.; Massenzio F.; Monti B.; Bolognesi M.L., Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease, «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 671 - 676 [Scientific article]

White MA; Kim E; Duffy A; Adalbert R; Phillips BU; Peters OM; Stephenson J; Yang S; MASSENZIO F; Lin Z; Andrews S; Segonds-Pichon A; Metterville J; Saksida LM; Mead R; Ribchester RR; Barhomi Y; Serre T; Coleman MP; Fallon JR; Bussey TJ; Brown RH Jr; Sreedharan J., Cite Share Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD, «NATURE NEUROSCIENCE», 2018, 21, pp. 1138 - 1138 [Scientific article]

Massenzio, Francesca; Peña-Altamira, Emiliano; Petralla, Sabrina; Virgili, Marco; Zuccheri, Giampaolo; Miti, Andrea; Polazzi, Elisabetta; Mengoni, Ilaria; Piffaretti, Deborah; Monti, Barbara*, Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose, «BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE», 2018, 1864, pp. 3771 - 3785 [Scientific article]

Peña-Altamira LE, Polazzi E, Giuliani P, Beraudi A, Massenzio F, Mengoni I, Poli A, Zuccarini M, Ciccarelli R, Di Iorio P, Virgili M, Monti B, Caciagli F., Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors., «NEUROCHEMISTRY INTERNATIONAL», 2018, 115, pp. 37 - 49 [Scientific article]

Matthew A White; Eosu Kim; Amanda Duffy; Robert Adalbert; Benjamin U Phillips; Owen M Peters; Jodie Stephenson; Sujeong Yang; MASSENZIO F; Ziqiang Lin; Simon Andrews; Anne Segonds-Pichon; Jake Metterville; Lisa M Saksida; Richard Mead; Richard R Ribchester; Youssef Barhomi; Thomas Serre; Michael P Coleman; Justin R Fallon; Timothy J Bussey; Robert H Brown Jr; Jemeen Sreedharan, TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD, «NATURE NEUROSCIENCE», 2018, 21, pp. 552 - 563 [Scientific article]

Profilo, E; Peña-Altamira, Le; Corricelli, M; Castegna, A; Danese, A; Agrimi, G; Petralla, S; Giannuzzi, G; Porcelli, V; Sbano, L; Viscomi, C; Massenzio, F; Palmieri, Em; Giorgi, C; Fiermonte, G; Virgili, M; Palmieri, L; Zeviani, M; Pinton, P; Monti, B; Palmieri, F; Lasorsa, Fm., Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells., «BIOCHIMICA ET BIOPHYSICA ACTA», 2017, 1863, pp. 1422 - 1435 [Scientific article]

Peña-Altamira, E; Petralla, S; Massenzio, F; Virgili, M; Bolognesi, Ml; Monti, B., Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease., «FRONTIERS IN AGING NEUROSCIENCE», 2017, 9, pp. 1 - 15 [Scientific article]

Peña-Altamira, E; Prati, F; Massenzio, F; Virgili, M; Contestabile, A; Bolognesi, Ml; Monti, B., Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation., «EXPERT OPINION ON THERAPEUTIC TARGETS», 2016, 20, pp. 627 - 640 [Scientific article]

Prati F;De Simone A;Bisignano P;Armirotti A;Summa M;Pizzirani D;Scarpelli R;Perez DI;Andrisano V;Perez-Castillo A;Monti B;Massenzio F;Polito L;Racchi M;Favia AD;Bottegoni G;Martinez A;Bolognesi ML;Cavalli A, Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors., «ANGEWANDTE CHEMIE. INTERNATIONAL EDITION», 2015, 54, pp. 1578 - 1582 [Scientific article]

Polazzi, E; Mengoni, I; Peña-Altamira, E; Massenzio, F; Virgili, M; Petralla, S; Monti, B., Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology., «JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY», 2015, 74, pp. 818 - 834 [Scientific article]

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