Foto del docente

Francesca Maffei

Assistant professor

Department for Life Quality Studies

Academic discipline: BIO/14 Pharmacology

Publications

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Publications prior to 2004

LAVORI IN EXTENSO

 

SOFFRITTI M., C. MALTONI, F. MAFFEI, R. BIAGI, (1989). Formaldehyde: an experimental multipotential carcinogen. Toxicol. Ind. Health; 5, 699-730.

HRELIA P., M. MOROTTI, F. VIGAGNI, F. MAFFEI, M. PAOLINI, G. CANTELLI FORTI, (1993). Murine a/ßinterferons inhibit benzo(a)pyrene activation and mutagenesis in mice. In: Antimutagenesis and Anticarcinogenesis Mechanisms III, (Bronzetti G. et al. Eds), Plenum Press, New York, pp 325-334.

HRELIA P., F. VIGAGNI, F. MAFFEI, G. CANTELLI FORTI, (1993). The Involvement of reactive oxygen species in the direct-acting mutagenicity of 5-nitro-3-thiophenecarboxanilides in Salmonella typhimurium; J. Environ. Pathol. Toxicol. Oncol.; 12 (4), 185-191.

RAGGI M.A., F. MAFFEI, F. BUGAMELLI, G. CANTELLI FORTI, (1994). Bioavailability of glycyrrhizin and licorice extract in rat and human plasma as detected by a HPLC method. Pharmazie; 49, 269-272.

HRELIA P., F. VIGAGNI, F. MAFFEI, M. MOROTTI, A. COLACCI, P. PEROCCO, S. GRILLI, G. CANTELLI FORTI, (1994). Genetic safety evaluation of pesticides in different short-term tests. Mutat. Res. (Genetic Toxicology); 321, 219-228.

HRELIA P., F. VIGAGNI, F. MAFFEI, M. PAOLINI, R. MESIRCA, L. POZZETTI, G. CANTELLI FORTI, (1994). A battery of biomarkers for detecting carcinogenic risk from fungicides. Clin. Chem.; 40 (7), 1460-1462.

HRELIA P., M. MOROTTI, F. VIGAGNI, F. MAFFEI, M. PAOLINI, R. MESIRCA, G. CANTELLI FORTI, (1994). The modulating activity of interferon on benzo(a)pyrene bioactivation and clastogenesis in mice. Pharmacol. Toxicol.; 74, 249-254.

HRELIA P., F. MAFFEI, F. VIGAGNI, C. FIMOGNARI, P. FLORI, R. STANZANI, G. CANTELLI FORTI, (1994). Interactive effects between trichloroethylene and pesticides at metabolic and genetic level in mice. Environ. Health Persp.; 102 (supp. 9), 31-34.

CANTELLI FORTI G., F. MAFFEI, P. HRELIA, F. BUGAMELLI, M. BERNARDI, P. D'INTINO, M. MARANESI, M.A. RAGGI, (1994). Interaction of licorice on glycyrrhizin pharmacokinetics. Environm. Health Persp.; 102 (supp.9), 65-68.

 HRELIA P., F. VIGAGNI, F. MAFFEI, C. FIMOGNARI, L. LAMARTINA, D. SPINELLI, P. JURIC, M.C. GUERRA, G. CANTELLI FORTI, (1995). Analysis of metabolism and genotoxicity of 5-nitro-3-thiophenecarboxanilides in bacterial, mammalian and human cells, Mutagenesis; 10, (3), 171-177.

PAOLINI M., R. MESIRCA, L. POZZETTI, F. MAFFEI, F. VIGAGNI, P. HRELIA, G. CANTELLI FORTI, (1996). Genetic and non-genetic biomarkers related to carcinogenesis in evaluating toxicological risk from Fenarimol. Mutat. Res. (Genetic Toxicology); 368, 27-39.

HRELIA P., F. MAFFEI, C. FIMOGNARI, F. VIGAGNI, G. CANTELLI FORTI, (1996). Cytogenetic effects of Metalaxyl on human and animal chromosomes. Mutat. Res. (Genetic Toxicology); 369, 81-86.

HRELIA P., C. FIMOGNARI, F. MAFFEI, F. VIGAGNI, R. MESIRCA, L. POZZETTI, M. PAOLINI, G. CANTELLI FORTI, (1996). The genetic and non-genetic toxicity of the fungicide Vinclozolin. Mutagenesis; 11 (5), 445-453.

 HRELIA P., C. FIMOGNARI, F. VIGAGNI, F. MAFFEI, G. CANTELLI FORTI, (1996). A cytogenetic approach to the study of genotoxic effects of fungicides: An in vitro study in lymphocyte cultures with Thiophanate-methyl. ATLA-Altern. Lab. Anim.; 24, 597-601.

HRELIA P., C. FIMOGNARI, F. MAFFEI, F. VIGAGNI, G. CANTELLI FORTI, (1996). Potential antimutagenic activity of Glycyrrhiza glabra extract. Phytother. Res.; 10, S101-S103.

CANTELLI FORTI G., M.A. RAGGI, F. BUGAMELLI, F. MAFFEI, A. VILLARI, N.M. TRIEF, (1997). Toxicological assessment of Liquorice: biliary excretion in rats. Pharmacol. Res.; 35, (5) 463-470.

HRELIA P., C. FIMOGNARI, F. MAFFEI, B. BRIGHENTI, L. GARUTI, S. BURNELLI, G. CANTELLI FORTI, (1998). Synthesis, metabolism and structure-mutagenicity relationships of novel 4-nitro-(imidazoles and pyrazoles) in Salmonella typhimurium. Mutat. Res. (Fundamental and Molecular Mechanisms of Mutagenesis), 397, 293-301.

CASTELLI E., P. HRELIA, F. MAFFEI, C. FIMOGNARI, F.G. FOSCHI, F. CAPUTO, G. CANTELLI FORTI, G.F. STEFANINI, G. GASBARRINI, (1999). Indicators of genetic damage in alcoholics: reversibility after alcohol abstinence. Hepato-Gastroenterol.; 46, 1664-1668.

 HRELIA P., C. FIMOGNARI, F. MAFFEI, D. SPINELLI, L. LAMARTINA, M.C. SARVA', G. CANTELLI FORTI, (1999). Influence of nitroreductase and O-acetyltransferase on the mutagenicity of substituted nitrobenzothiophenamines in Salmonella typhimurium. Chem.-Biol.Interact.; 118, 99-111.

MAFFEI F., F. VIGAGNI, H. NORPPA, P. HRELIA, (1999). Bromodeoxyuridine labelling as an alternative method to identify 6-thioguanine-resistant mutant lymphocytes in humans. Mutat. Res. (Fundamental and Molecular Mechanisms of Mutagenesis); 431, 223-231.

MAFFEI F., C. FIMOGNARI, E. CASTELLI, G.F. STEFANINI, G. CANTELLI FORTI, P. HRELIA, (2000). Increased cytogenetic damage detected by FISH analysis on micronuclei in peripheral lymphocytes from alcoholics. Mutagenesis; 15 (6), 517-523.

MAFFEI F., G. CANTELLI FORTI, E. CASTELLI, G.F. STEFANINI, S. MATTIOLI, P. HRELIA, (2002). Biomarkers to assess the genetic damage induced by alcohol abuse in human lymphocytes. Mutat. Res. (Genetic Toxicology and Environmental Mutagenesis); 514, 49-58.

HRELIA P., C. FIMOGNARI, F. MAFFEI, G. BRANDI, G. BIASCO, G. CANTELLI FORTI, (2002). Mutagenic and clastogenic activity of gastric juice in human gastric diseases. Mutat. Res. (Genetic Toxicology and Environmental Mutagenesis); 514, 125-132.

MAFFEI F., S. ANGELINI, G. CANTELLI FORTI, V. LODI, F.S. VIOLANTE, S. MATTIOLI, P. HRELIA, (2002) Micronuclei frequencies in hospital workers occupationally exposed to low levels of ionizing radiation: influence of smoking status and other factors. Mutagenesis; 17 (5), 405-409.

HRELIA P., F. MAFFEI, S. ANGELINI, G. CANTELLI FORTI. (2003) Biomarkers of effects and susceptibility for risk assessment. G. Ital. Med. Lav. Ergon., 25, 342-343.

MAFFEI F., S. ANGELINI, G. CANTELLI FORTI, F.S. VIOLANTE, V. LODI, S. MATTIOLI, P. HRELIA, (2004). Spectrum of chromosomal aberrations in peripheral lymphocytes of hospital workers occupationally exposed to low doses of ionizing radiation. Mutat. Res. (Fundamental and Molecular Mechanisms of Mutagenesis); 547, 91-99.

HRELIA P., F. MAFFEI, S. ANGELINI, G. CANTELLI FORTI, (2004). A molecular epidemiological approach to health risk assessment of urban air pollution. Toxicol. Lett.; 149, 261-267.

ANGELINI S., R. KUMAR, F. CARBONE, F. MAFFEI, G. CANTELLI FORTI, F.S. VIOLANTE, V. LODI, S. CURTI, K. HEMMINKI, P. HRELIA, (2005). Micronuclei in humans induced by exposure to low level of ionizing radiation: influence of polymorphisms in DNA repair genes. Mutat. Res. (Fundamental and Molecular Mechanisms of Mutagenesis); 570, 105-117.

MAFFEI F., P. HRELIA, S. ANGELINI, F. CARBONE, G. CANTELLI FORTI, A. BARBIERI, G. SANGUINETTI, S. MATTIOLI, F.S. VIOLANTE, (2005). Effects of environmental benzene: Micronucleus frequencies and haematological values in traffic police working in an urban area. Mutat. Res. (Genetic Toxicology and Environmental Mutagenesis); 583, 1-11.

MAFFEI F., A. BUSCHINI, C. ROSSI, P. POLI, G. CANTELLI FORTI, P. HRELIA, (2005). Use of the Comet test and micronucleus assay on human white blood cells for in vitro assessment of genotoxicity induced by different drinking water disinfection protocols. Environ. Mol. Mutagen.; 46,116-125.

MAFFEI F., A. TAROZZI, F. CARBONE, A. MARCHESI, S. HRELIA, C. ANGELONI, G. CANTELLI FORTI, P. HRELIA (2007). Revelance of apple consumption for protection against oxidative damage induced by hydrogen peroxide in human lymphocytes. Br.J. Nutr.; 97, 921-927.

MARABINI L., S. FRIGERIO, E. CHIESARA, F. MAFFEI, G. CANTELLI FORTI, P HRELIA, A. BUSCHINI, A. MARTINO, P. POLI, C. ROSSI, S. RADICE (2007). In vitro cytotoxicity and genotoxicity of chlorinated drinking waters sampled along the distribution system of two municipal networks. Mutat. Res. (Genetic Toxicology and Environmental Mutagenesis); 634, 1-13.

ANGELINI S., R. KUMAR, F. CARBONE, J.L. BERMEJO, F. MAFFEI, G. CANTELLI FORTI, K. HEMMINKI, P. HRELIA, (2008).Inherited susceptibility to bleomycin-induced micronuclei: correlating polymorphisms in GSTT1, GSTM1 and DNA repair genes with mutagen sensitivity. Mutat. Res. (Fundamental and Molecular Mechanisms of Mutagenesis); 638,90-97.

MAFFEI F. F. CARBONE, S. ANGELINI, G. CANTELLI FORTI, H. NORPPA, P. HRELIA (2008). Micronuclei frequency induced by bleomycin in human peripheral lymphocytes: correlationg BLHX polymorphism with mutagen sensitivity. Mutat. Res. (Fundamental and Molecular Mechanisms of Mutagenesis); 639, 20-26.

 

SHORT COMMUNICATIONS

 

VIGAGNI F., P. HRELIA, F. MAFFEI, G. BIASCO, G. BRANDI, G. CANTELLI-FORTI, (1995). Biomarkers of genetic activity in the study in the of achlorhidric stomach. Pharmacol. Toxicol.; 76 (supp. 1), 9.

HRELIA P., F. MAFFEI, F. VIGAGNI, R. MESIRCA, M. PAOLINI, L. POZZETTI, G. CANTELLI-FORTI, (1995). Genetic and biochemical markers as predictors of carcinogenic effects of pesticides. Pharmacol. Toxicol.; 76 (supp. 1), 18.

HRELIA P., C. FIMOGNARI, F. MAFFEI, F. VIGAGNI, G. CANTELLI FORTI, (1997). A molecular approach for the study of genetic damage in alcoholics. Pharmacol. Res., 35, 234.

FIMOGNARI C., M. NÜSSE, F. MAFFEI, G. CANTELLI FORTI, P. HRELIA, (1999). Induction of DNA damage and effect on cell cycle progression by Thiophanate-Methyl. Pharmacol. Toxicol.; 85 (supp. II), 8.

MAFFEI F., S.M. HOU, B. LAMBERT, P. HRELIA, (1999). Gene mutations induced by acetaldehyde in human lymphocytes exposed in vitro. Pharmacol. Toxicol.; 85 (supp. II), 14.

 

PUBBLICAZIONI SU LIBRI ED ATTI DI CONGRESSI

 

HRELIA P., M. MOROTTI, F. VIGAGNI, F. MAFFEI, G. CANTELLI FORTI, (1991). Valutazione del rischio genotossico da tre erbicidi in una batteria di tests a breve termine. Atti dell'8° Simposio Chimica degli Antiparassitari. I Disserbanti (G.Biagini Ed.), Lucca, pp195-201.

CANTELLI FORTI G., P. HRELIA, F. MAFFEI, R. MESIRCA, M. MOROTTI, M. PAOLINI, L. POZZETTI, E. SAPIGNI, F. VIGAGNI, (1992). Studio della potenzialità iniziante e promuovente nella valutazione del rischio carcinogeno da antiparassitari. Consiglio Nazionale delle ricerche, Atti del I° Convegno "Progetto Finalizzato Prevenzione e Controllo dei Fattori di Malattia" (Eds: E. Chiesara, E. Morichetti, C. Della Croce, G. Bronzetti) pp 107-112.

CANTELLI FORTI G., F. MAFFEI, F. VIGAGNI, C. FIMOGNARI, P. HRELIA, (1994). Uso ed abuso di etanolo: aspetti tossicologici ed effetti interattivi. Atti della riunione scientifica “Alcolismo e medicina legale”. (a cura di D. Vasapollo, A. Becca), Ospedale Militare Bologna, pp.104-134.

FIMOGNARI C., F. VIGAGNI, F. MAFFEI, P. HRELIA, G. CANTELLI-FORTI, (1994). Ottimizzazione di una tecnica per la valutazione quali-quantitativa dei micronuclei nel roditore. Atti del II Convegno Progetto Finalizzato Prevenzione e Controll dei Fattori di Malattia (Bronzetti G., Cini M., Chiesara E., Eds.), pp. 431-437.

FIMOGNARI C., F. MAFFEI, F. VIGAGNI, P. HRELIA, (1995).Proprietà antimutagene dell'estratto puro di Glycyrrhiza glabra. In: Farmacognosia: Moderni sviluppi di una scienza antica (Speroni E., Hrelia P., Eds) Patron, Bologna, pp. 25-35.

CANTELLI-FORTI G., F. MAFFEI, A. ROSSETTI, E. SAPIGNI, (1995). Studio farmacocinetico della glicirizzina e dell'acido glicirretico per la valutazione del rischio tossicologico dell'estratto di Glycyrrhiza glabra. In: Farmacognosia: Moderni sviluppi di una scienza antica (Speroni E., Hrelia P., Eds) Patron, Bologna, pp.63-74.

CANTELLI FORTI G., F. MAFFEI, (2000). Principi di Tossicologia Generale. In: Tossicologia molecolare e cellualre (Cantelli Forti G., Galli C.L., Hrelia P., Marinovich M., Eds), UTET, Torino, pp. 3-7.

CANTELLI FORTI G., F. MAFFEI, (2001). Meccanismi di tossicità dei funghi superiori. Atti del 2° Convegno internazionale di Micologia, Viterbo 6-7 Dicembre 2001, pp 63-71.

CANTELLI FORTI G., F. MAFFEI, (2005). Principi di Tossicologia. In: FARMACOLOGIA – Principi di base e applicazioni terapeutiche (Rossi F., Cuomo V., Riccardi C., Eds), Edizioni Minerva Medica, Torino, pp. 859-864.

CANTELLI FORTI G., F. MAFFEI, (2005). Micotossine: aspetti tossicologici. In: I GEORGOFILI-QUADERNI-2005-III, Firenze pp.127-139.