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Elisabetta Ciani

Associate Professor

Department of Biomedical and Neuromotor Sciences

Academic discipline: BIO/09 Physiology

Publications

Gennaccaro L.; Fuchs C.; Loi M.; Roncace V.; Trazzi S.; Ait-Bali Y.; Galvani G.; Berardi A.C.; Medici G.; Tassinari M.; Ren E.; Rimondini R.; Giustetto M.; Aicardi G.; Ciani E., A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder, «NEUROBIOLOGY OF DISEASE», 2021, 153, pp. 105304 - 105304 [Scientific article]

Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvani G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E., Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death, «AGING AND DISEASE», 2021, 12, pp. 764 - 785 [Scientific article]

Galvani, Giuseppe; Mottolese, Nicola; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Tassinari, Marianna; Fuchs, Claudia; Ciani, Elisabetta; Trazzi, Stefania, Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder, «JOURNAL OF NEUROINFLAMMATION», 2021, 18, pp. 155 - 175 [Scientific article]

Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Giuseppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta, Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2021, 22, pp. 1 - 24 [Scientific article]

Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani, Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist, in: FENS 2020 e-Posters, 2020(atti di: FENS 2020, Virtual, 11-15 july 2020) [Poster]

Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E., Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons, «MOLECULAR NEUROBIOLOGY», 2020, 30, pp. 12035 - 12054 [Scientific article]

Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O.; Rimondini R.; Ciani E., Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder, «NEUROPHARMACOLOGY», 2020, 167, pp. 107746 - 107764 [Scientific article]

Trovo L.; Fuchs C.; De Rosa R.; Barbiero I.; Tramarin M.; Ciani E.; Rusconi L.; Kilstrup-Nielsen C., The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo, «NEUROBIOLOGY OF DISEASE», 2020, 138, pp. 104791 - 104803 [Scientific article]

Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E., CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019), «BRAIN PATHOLOGY», 2019, 29, pp. 658 - 674 [Scientific article]

Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rimondini R.; Aicardi G.; Ciani E., Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist, «FRONTIERS IN CELLULAR NEUROSCIENCE», 2019, 13, pp. 1 - 15 [Scientific article]Open Access

Lupori L.; Sagona G.; Fuchs C.; Mazziotti R.; Stefanov A.; Putignano E.; Napoli D.; Strettoi E.; Ciani E.; Pizzorusso T., Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder, «HUMAN MOLECULAR GENETICS», 2019, 28, pp. 2851 - 2861 [Scientific article]Open Access

Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchina; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta*, CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder, «HUMAN MOLECULAR GENETICS», 2018, 27, pp. 1572 - 1592 [Scientific article]

Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martire, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta*, Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder, «NEURAL PLASTICITY», 2018, 2018, pp. 1 - 18 [Scientific article]Open Access

Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, Elisabetta*, Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice, «EUROPEAN JOURNAL OF NEUROSCIENCE», 2018, 47, pp. 1054 - 1066 [Scientific article]

Lo Martire, Viviana; Alvente, Sara; Bastianini, Stefano; Berteotti, Chiara; Silvani, Alessandro; Valli, Alice; Viggiano, Rocchina; Ciani, Elisabetta; Zoccoli, Giovanna, CDKL5 deficiency entails sleep apneas in mice, «JOURNAL OF SLEEP RESEARCH», 2017, 26, pp. 295 - 297 [Scientific article]

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