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Special Issue - Personalised Medicine in Hypertension
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Message from the Guest Editors
Dear Colleagues,
High blood pressure is still the leading risk factor for death
and disability worldwide. Patients at high cardiovascular
risk require intensive drug therapy for controlling blood
pressure and other risk factors. The current therapeutic
approach is based on the results of several clinical trials,
assuming that subjects have common phenotypes and
following algorithms derived from large population studies.
This “one size fits all” approach improved hypertension
control in the general population, requiring little or no
information about individuals, and requires low medical
investment. While this is the case, hypertension control is
far from being satisfactory globally, and other strategies are
required for its management. A personalized approach to
hypertension is based on information that integrates data
from clinical research, systems biology, ‘omics’
technologies, imaging findings, and e-technology, together
with a patient’s involvement in clinical care. This could
implement knowledge of the specific disease
pathophysiology of patients and peculiar responses to
treatment.
