Davide Martelli

Associate Professor, Qualified for the position of Full Professor of Physiology in Italy (2022-2031)

PERSONAL INFORMATION

Family name, First name: Martelli, Davide

URL for web site: https://www.unibo.it/sitoweb/d.martelli/en

E-mail: d.martelli@unibo.it

BIOGRAPHY

Davide Martelli is the discoverer of the splanchnic anti-inflammatory pathway, the efferent arm of the inflammatory reflex, an endogenous neural reflex that controls immune function during the course of an infection. Davide Martelli completed his PhD (2009) at the University of Bologna. In 2010, he moved to the Florey Institute of Neuroscience and Mental Health (Melbourne, Australia) to study the sympathetic control of immune function, with Prof Robin McAllen and Prof Michael McKinley. In 2016, he returned to Bologna, where he became Associate Professor of Physiology (2022) at the University of Bologna. He has won several awards for his studies, including an Early Career/Postdoctoral Award from the American Physiological Society (2014) and an IBRO Return Home Fellowship (2015). He is member of the working group of the University of Bologna for the “emerging infectious diseases”.

EDUCATION

25/05/2009 PhD in Neurophysiology

Dept. of Human and General Physiology, University of Bologna, Italy.

14/03/2003 Master Degree in Biological Sciences – Biomolecular address, University of Bologna, Italy (degree score 110/110)

CURRENT POSITION(S)

18/02/2022 – Today Associate Professor

Dept. of Biomedical and Neuromotor Science (DIBINEM), University of Bologna, Italy

PREVIOUS POSITIONS

18/02/2019 – 17/02/2022 Senior Assistant Professor, DIBINEM, University of Bologna, Italy

18/02/2016 – 17/02/2019 Junior Assistant Professor, DIBINEM, University of Bologna, Italy

18/02/2016 – 17/02/2019 Senior Research Officer (honorary position),The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia

01/02/2013 – 17/02/2016 Senior Research Officer, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia

05/09/2012 – 31/01/2013 Postdoctoral Researcher, Dept. of Human and General Physiology (now DIBINEM), University of Bologna, Italy.

01/12/2010 – 04/09/2012 Visiting Fellow, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia

25/05/2009 – 30/11/2010 Postdoctoral Researcher , Dept. of Human and General Physiology, University of Bologna, Italy.

FUNDING RECEIVED

2022: Associate Investigator - Italian National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.3 - NextGenerationEU – NextGenerationEU (Project INF-ACT 114.5M EUR)

2022: ALMArie CURIE offered by UNIBO (10.000 EUR)

2021: Grant UNIBO-DIBINEM to co-finance a post-doc salary (11.894 EUR).

2021: Grant (PI) offered by CARISBO Foundation (10.000 EUR)

2019: Grant UNIBO-DIBINEM to co-finance a post-doc salary (11.894 EUR).

2019: Associate Investigator – NHMRC Australian Research Project Grant – GNT11863684 (600.000 AU$).

2019: Associate Investigator – NHMRC Australian Research Project Grant – GNT11863682 (620.000 AU$).

2015: Chief Investigator A (PI) – NHMRC Australian Research Project Grant – GNT1098887 (613.466 AU$).

2015: Awarded (PI) with a IBRO Fellowship (10.000 EUR)

2011: Winner (PI) of a “Medical research & Technology equipment grant” (24.150 AU$) offered by The William Buckland Foundation.

2010: Recipient (PI) of a European Research Grant (15.000 EUR) offered by Sanofi-Aventis for the European Sleep Research Society (ESRS).

2009: Co-Investigator - Italian Ministerial grant PRIN 2009 - prot. 2009SPTHRK_001 (62.262 EUR).

FELLOWSHIPS, PRIZES AND AWARDS

2022: “Best oral communication” Prize (500 EUR) at the 72^nd national congress of the Italian Society of Physiology (SIF). SIF2022. Bari, Italy.

2022: Participant to EU Marie Curie Staff Exchange Project "Platypus"

2021: Ranked amongst the top 0,15% experts in “Autonomic Pathways” in Expertscape. https://expertscape.com/au/autonomic+pathways/Martelli%2C+D

2018: Selected for the symposium “Featured Topic - NCAR Hot Topics in Autonomic Regulation” sponsored by the American Physiological Society (250US$ + conference fee waived). EB2018. San Diego, California USA, April 21-25, 2018.

2017: Participant to EU Marie Curie Staff Exchange Project "Platypus"

2015: Awarded with a IBRO Fellowship (10.000 EUR)

2014: Best original review published in 2013 at the Florey (from the Florey Postdoctoral Association). Melbourne, Victoria, Australia.

2014: Merck-Millipore travel award (500 AU$), Melbourne, Victoria, Australia to attend EB2014 in San Diego, USA.

2014: F1000 (Faculty of 1000) Reccomendation: Jänig W: F1000Prime Recommendation of [Martelli D et al., J Physiol (Lond) 2014]. In F1000Prime, 06 Feb 2014; DOI: 10.3410/f.718236549.793490418. F1000Prime.com/718236549#eval793490418.

2014: “Post-doctoral/Early Career Investigator Award” from the American Physiological Society (Neural Control/Autonomic Regulation section, 500 US$ + conference fee waived). San Diego, California, USA.

2013: “Best oral presentation” (500 AU$) at the annual meeting of the Florey Postdoctoral Association. Melbourne, Victoria, Australia.

2012: “Best communication at a conference” (500 AU$) from the Florey Postdoctoral Association, Melbourne, Victoria, Australia.

2011: IBRO travel grant (1.250 EUR) to participate to the 8th IBRO world congress (14-18, July 2011, Firenze, Italy).

2010: Travel grant (500 EUR) to participate to the 20th meeting of the ESRS (14-18, September 2010, Lisboa, Portugal).

2010-2013: 3 Post-Doctoral fellowships at the Department of Human and General Physiology, University of Bologna, Italy.

2009: European Marie Curie scholarship to participate at the European Marie Curie Action “Training in Sleep Research and Sleep Medicine” organized by the European Sleep Research Society (ESRS).

2008: Scholarship at the Department of Human and General Physiology, University of Bologna, Italy.

2004: National ministerial scholarship to frequent the doctorate in Neurophysiology at the University of Bologna, Italy.

2003: Scholarship at the Department of Human and General Physiology, University of Bologna, Italy.

2000: European Socrates/Erasmus scholarship (6 months at the University of Bödenkultur, Vienna, Austria)

ORGANISATION OF SCIENTIFIC MEETINGS

2023: Organizer, Chair and Speaker in a symposium that will be held during IBRO2023 (International Brain Research Organization, September 09-13, 2023) – “Nervous about your immune system? How the autonomic nervous system controls immunity”. Speakers: Davide Martelli, Fernanda Brognara, Wouter de Jonge, Connie Wong.

2019: Organizer, Chair and Speaker in a symposium held during the ISAN2019 (Los Angeles, USA, July 25-27, 2019) – Symposium Title: “Autonomic control of inflammation; new insights into pathways and mechanisms”. Sponsored by Livanova PLC. Speakers: Davide Martelli, Paul O’ Connor, Colin Reardon, Rainer Straub.

2015: Organizer, Chair and Speaker in a symposium held during the ISAN2015 conference of the International Society for Autonomic Neuroscience in conjunction with Federation of European Autonomic Societies, American Autonomic Society and Japan Society of Neurovegetative Research (Stresa, Italy, September 26-29, 2015) – Symposium Title: “Nervous about inflammation? How the autonomic nervous system influences immune function”. Sponsored by Experimental Physiology. Speakers: Davide Martelli, Ruud Buijs, Georg Pongratz.

2011, 2013: Chair at the Florey postdoctoral annual meetings. Melbourne. VIC Australia.

2010: Chair at the oral blitz session on basic research in sleep, final symposium of the Marie Curie Action “Training in sleep research and sleep medicine”. Kloster Seeon, Germany, 02-06 July 2010.

2010: Chair at the symposium held at the Department of Human and General Physiology, University of Bologna (Italy), within the European Marie Curie Action “Sleep Research and Sleep Medicine Education Program” organized by the European Sleep Research Society (ESRS).

INSTITUTIONAL RESPONSIBILITIES

2022-now: Component of the working group for UNIBO for the partnership “emerging infectious diseases” for the PNRR (the National Recovery and Resilience Plan).

2021-now: Member of the Commission for the Quality of the Physiotherapy Bachelor Course, School of Medicine and Surgery, University of Bologna.

2019-now: Faculty member of the Master in Pediatric Urology, University of Bologna

2014: Part of the School Outreach Team of the Florey Institute of Neuroscience and Mental Health. During the Brain Awareness Week (March 2014), I was invited to give a talk on the Neurobiology of Sleep at a local High School in Melbourne.

2014: Nominated from The Florey Institute as post-doctoral representative to attend the First Commonwealth Science Conference in Bangalore, India (25-28 November 2014).

COMMISSIONS OF TRUST

2023: Faculty member of the “European School of Pain”. https://eps2023.azuleon.org/

2022-Today: Registered in REPRISE (the Register of Scientific Experts set up at the MIUR, Italian Minister of University and Research) for the following sections: Fundamental research

2022-Today: Editorial Board – Neuroimmunomodulation

2021-Today: Reviewer for the Italian National Agency For The Evaluation Of Universities And Research Institutes (ANVUR)

2021-Today: Editorial Board – Topic Editor - Cells

2019-Today: Editorial Board – Review Editor – Frontiers in Neuroscience

2019-Today: Editorial Board – Review Editor – Frontiers in Neuroanatomy

2019-Today: Editorial Board – Review Editor – Frontiers in Physiology

2018: Member of the scientific advisory board of Livanova Plc (>4000 employees in more than 100 countries around the world, gros capital >4B US$)

2018-Now: Associate member Faculty of 1000 / Pharmacology & Drug Discovery / Cardiovascular Pharmacology. https://facultyopinions.com/prime/thefaculty/member/1052599

2018: Member of the commission for the MPhil in Medical Science for the candidate Flavia Peci. Department of Hematology, University of Cambridge

2013-2016: Member of the panel for doctorate supervision at the University of Melbourne for the PhD candidate Giancarlo Allocca

2014-Now: Editorial Board – Journal of Immune Research

Invited Peer-Reviewer for the following journals: Neurogastroenterology and Motility, Brain Behavior and Immunity, Clinical and Experimental Pharmacology and Physiology, Journal of Neurophysiology, Autonomic Neuroscience: Basic and Clinical, Brain Behavior and Immunity, American Journal of Physiology (Reg. Integr. Comp. Physiol.), Frontiers in Neuroscience, Alimentary Pharmacology & Therapeutics and many others.

MEMBERSHIPS OF SCIENTIFIC SOCIETIES

Italian Society for Neuroscience (2011-2018), Federation of European Neuroscience Societies (2011-2018), Australasian Society for Neuroscience (2011-2014), Society for Neuroscience (2013-2014), American Physiological Society (2013-Now), International Society for Autonomic Neuroscience (2014-Now).

MAJOR COLLABORATIONS

Robin McAllen, Michael McKinley, Song Yao, Neural control of immunity, Florey Institute of Neuroscience and Mental Health, Australia. Erica Sloan, Cancer and autonomic nervous system, Monash University, Australia. Clive May, Lindsea Booth, Yugeesh Lankadeva Heart failure and sepsis, Florey Institute of Neuroscience and Mental Health, Australia. Wouter de Jonge, Neural control of immunity, University of Amsterdam, Netherlands. Alexandre Steiner, Neural control of immunity, University of Sao Paulo, Brazil.

INVITED PRESENTATIONS

Invited seminars:

1. Monash University – The splanchnic anti-inflammatory pathway, a sympathetic pathway controlling immune function – Melbourne, VIC Australia. 21/11/2022.
2. University of Helsinki – The inflammatory reflex – Helsinki, Finland. 11/03/2016.
3. University of Bologna - Neural control of immune function: The inflammatory reflex – Bologna, Italy. 23/04/2015.
4. Flinders University - Neural Control of Immune Function - Adelaide, SA Australia. 08 May 2013.
5. University of Sydney - Thermoregulatory but not Osmoregulatory impairment characterizes REM Sleep - Sydney, NSW Australia.04/11/2011
6. Florey Institutes Neuroscience Seminar Series - Physiological regulations during the wake sleep cycle - Howard Florey Institute, Melbourne, VIC Australia, 28 June 2011.

Oral Communications:

1. Central Cardiovascular Control: Future Directions. Melbourne, VIC Australia, December 02-03 2022.
2. ISAN 2019. Invited speaker in the symposium “Autonomic control of inflammation; new insights into pathways and mechanisms”. Los Angeles, California USA, July 25-27, 2019.
3. EB 2018. Invited speaker in the symposium “Featured Topic - NCAR Hot Topics in Autonomic Regulation”. San Diego, California USA, April 21-25, 2018.
4. ISAN 2017. Invited speaker in the symposium “Targeting the autonomic nervous system to alleviate inflammatory disorders". Nagoya, Japan, Aug 30 – Sep 2, 2017.
5. EB 2017. Invited speaker in the symposium “Sympathetic Nerves and Inflammation: The Pro and the Anti”. Chicago, IL, USA, April 22-26, 2017
6. International Society for Autonomic Neuroscience (ISAN) 2015. Stresa, Italia, 26-29 September 2015.
7. Central Cardiovascular Respiratory Control: Future Directions. Melbourne, VIC Australia, 15-16 September 2014.
8. Experimental Biology (EB) 2014. San Diego, California USA, 26-30 April 2014.
9. Florey Postdoctoral Annual Meetings 2011, 2013.
10. 20th international congress of the European Sleep Research Society. Lisbon, Portugal, 14-18 September 2010.
11. Central Cardiovascular Control: Future Directions. Melbourne, VIC Australia, 20-21 October 2011.
12. Marie Curie Action “Training in sleep research and sleep medicine”. Kloster Seeon, Germany, 02-06 July 2010.
13. PENS – Marie Curie Summer school. Bertinoro (FC), Italy, 08-13 May 2009.
14. First annual meeting of Italian PhD students in physiology. Pontignano (Si), Italy, 18-21 July 2007.

Poster Communications:

I participated to several National and International meetings or conferences with poster communications. Amongst them:

Federation of European Physiological Societies (FEPS). Bologna, Italy 10-13/09/2019

Experimental Biology (EB) 2014, 2017, 2018. USA.

33rd Meeting of the Australian Neuroscience Society (ANS). Melbourne, VIC Australia, 3-6/02/2013

8th IBRO world congress. Firenze, Italia, 14-18/07/2011

SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS

2023-Today: 1 PhD student (Supervisor), 1 PhD student (contributing to the supervision), 1 PostDoc researcher (Tutor), DIBINEM, University of Bologna, Italia.

2021-2022 Today: 1 PostDoc researcher (Tutor), 1 PhD student (contributing to the supervision), DIBINEM, University of Bologna, Italia.

2020-2021: 1 PhD student (supervisor), 1 PhD student (contributing to the supervision), DIBINEM, University of Bologna, Italia.

2018 – 2020: 2 PhD students (contributing to the supervision), 1 bachelor student (supervisor) - Physiotherapy, 1 bachelor student (co-supervisor) – Biotechnology and 1 PostDoc researcher (tutor) DIBINEM, University of Bologna, Italia.

2015-2019: 2 PostDoc and 1 Senior Technician, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, 1 PhD student at DIBINEM and 2 Master students at DIBINEM

2017: 1 student (co-supervisor) – School of Medicine and Surgery, 1 student (contributing to the supervision) – School of Medicine and Surgery, University of Bologna, Italy

2016: 1 Master student (supervisor) – Medical Biotechnology, University of Bologna, Italia.

2012-2015: 2 PhD students and 1 Medical Doctor trainee, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia

2009: 1 PhD student (contributing to the supervision), Dept. of Human and General Physiology, University of Bologna, Italia

2008: 1 Master student (contributing to the supervision) – Biological Sciences, University of Bologna, Italia

PUBLICATIONS

2023

1. Peiris R.M., May C.N., Booth L.C., McAllen R.M., McKinley M.J., Hood S., Martelli D., Bellomo R., Lankadeva Y.R. Splanchnic sympathetic nerve denervation improves bacterial clearance and clinical recovery in established ovine Gram-negative bacteremia. Int Care Med Exp, 11 (1), 2023: 53.
2. Squarcio F., Hitrec T., Luppi M, Martelli D., Occhinegro A., Piscitiello E., Taddei L., Tupone D., Amici R., Cerri M. Ultrasonic vocalisations during rapid eye movement sleep in the rat. J Sleep Res, 2023: e13993.
3. Occhinegro A., McAllen R.M., McKinley M.J., Martelli D. Acute inhibition of inflammation mediated by sympathetic nerves: the inflammatory reflex. Neuroimmunomodulation, 30, 2023: 135-142.
4. Squarcio F., Hitrec T., Piscitiello E., Cerri M., Giovannini C., Martelli D., Occhinegro A., Taddei L., Tupone D., Amici R., Luppi M. Synthetic torpor triggers a regulated mechanism in the rat brain, favoring the reversibility of Tau protein hyperphosphorylation. Front Physiol, 2022: 1129278.
5. Martelli D., Brooks V.L. Leptin Increases: Physiological Roles in the Control of Sympathetic Nerve Activity, Energy Balance, and the Hypothalamic–Pituitary–Thyroid Axis. Int J Mol Sci, 24 (3), 2023: 2684.

   2022

6. McKinley M.J., Martelli D., Trevizan-Bau P., McAllen R.M. Divergent splanchnic sympathetic efferent nerve pathways regulate IL‐10 and TNF responses to endotoxaemia. J Physiol, 600 (20), 2022: 4521-4536.
7. Martelli D. The inflammatory reflex reloaded. Brain Behavior and Immunity, 104, 2022: 137-138.
8. McAllen R.M., McKinley M.J., Martelli D. Reflex regulation of Systemic Inflammation by the Autonomic Nervous System. Auton Neurosci, 237, 2022:102926.

   2021

9. Occhinegro A., Wong C.Y., Chua B. Y., Jackson D.C., McKinley M.J., McAllen R.M. Martelli D. The endogenous inflammatory reflex inhibits the inflammatory response to different immune challenges in mice. Brain Behavior and Immunity, 97, 2021: 371-375.
10. Hitrec T., Squarcio F., Cerri M., Martelli D., Occhinegro A., Piscitiello E., Tupone D., Amici R., Luppi M. Reversible Tau phosphorylation induced by synthetic torpor in the spinal cord of the rat. Front Neuroanat, 15(3), 2021: 592288.

    2020

11. Lankadeva Y.R., May C.N., McKinley M.J.; Neeland M.R., Ma S., Hocking D.M., Robins-Browne R., Bedoui S., Farmer D.G.S., Bailey S.R., Martelli D., McAllen R.M. Sympathetic nerves control bacterial clearance. Sci Rep, 10 (1), 2020: 15009.

    2019

12. Hitrec T., Luppi M., Bastianini S., Squarcio F., Berteotti C., Lo Martire V., Martelli D., Occhinegro A., Tupone D., Zoccoli G., Amici R., Cerri M. Neural control of fasting-induced torpor in mice. Sci Rep, 9 (1), 2019: 15462.
13. Decataldo F., Cramer T., Martelli D., Gualandi I., Korim W. S., Yao S. T., Tessarolo M., Murgia M., Scavetta E., Amici R., Fraboni B. Stretchable Low Impedance Electrodes for Bioelectronic Recording from Small Peripheral Nerves. Sci Rep, 9, 2019: 10598.
14. Luppi M., Cerri M., Di Cristoforo A., Hitrec T., Dentico D., Del Vecchio F., Martelli D., Perez E., Tupone D., Zamboni G., Amici R. c-Fos expression in the Limbic Thalamus following thermoregulatory and wake-sleep changes in the rat. Exp Brain Res, 237 (6), 2019: 1397-1407.
15. Allocca G., Ma S., Martelli D., Cerri M., Del Vecchio F., Bastianini S., Zoccoli G., Amici R., Morairty S.R., Aulsebrook A.E., Blackburn S. Lesku J.A., Rattenborg N.C., Vyssotski A.L., Wams E., Porcheret K., Wulff K., Foster R., Chan J.K.M., Nicholas C.L., Freestone D.R., Johnston L.A., Gundlach A.L. Validation of ‘Somnivore’, a Machine Learning Algorithm for Automated Scoring and Analysis of Polysomnography Data. Frontiers in Neuroscience, 2019. EPub. doi: 10.3389/fnins.2019.00207
16. Martelli D., Farmer D.G.S., McKinley M.J., Yao S.T., McAllen R.M. The anti-inflammatory reflex action of the splanchnic sympathetic nerves is distributed across abdominal organs. Am J Physiol Regul Int Comp Physiol, 316 (3), 2019: R235-R242.
17. *Walker A.K., *Martelli D., Ziegler A. I., Lambert G.W., Phillips S.E., Hill S.J., McAllen R.M., Sloan E.K. Circulating epinephrine is not required for chronic stress to enhance metastasis. Psychoneuroendocrinology, 99, 2019: 191-195. *Joint first authors.

    2018

18. Komegae E.N., Farmer D.G.S., Brooks V.L., McKinley M.J., McAllen R.M., Martelli D.Vagal afferent activation suppresses systemic inflammation via the splanchnic anti-inflammatory pathway. Brain Behavior and Immunity, 73, 2018: 441-449.
19. McKinley M.J., Martelli D., Pennington G.L., Trevaks D., McAllen R.M. Integrating the competing demands of osmoregulatory and thermoregulatory homeostasis. Physiology, 33 (3), 2018: 170-181.

    2017

20. Luppi M., Al-Jahmany A.A., Del Vecchio F., Cerri M., Di Cristoforo A., Hitrec T., Martelli D., Perez E., Zamboni G., Amici R. Wake-sleep and cardiovascular regulatory changes in rats made obese by a high-fat diet. Behav Brain Res, 320, 2017: 347-355.

    2016

21. Martelli D., Farmer D.G.S., Yao S.T. The splanchnic anti-inflammatory pathway: Could it be the efferent arm of the inflammatory reflex? Exp. Physiol. 101(10), 2016: 1245-1252. Note: This paper was highlighted in the cover of the October issue.

    2015

22. Anderson C.R., McKinley M.J., Martelli D., McAllen R.M. Letter to the editor: Parasympathetic innervation of the rodent spleen? Am. J Physiol Heart Circ Physiol, 309(12), 2015: H2158.
23. McKinley M.J., Yao S.T., Uschakov A., McAllen R.M., Rundgren M., Martelli D. The median preoptic nucleus: front and centre for regulation of body fluid, sodium, temperature, sleep and cardiovascular homeostasis. Acta Physiologica, 214(1), 2015: 8-32.
24. McAllen R.M., Cook A.D., Khiew H.W., Martelli D., Hamilton J.A. The interface between cholinergic pathways and the immune system and its relevance to arthritis. Arthritis Res Ther, 17(1) 2015: 87.
25. Martelli D., Silvani A., McAllen R.M., May C.N., Ramchandra R. Reply to “Letter to the editor: Does low-frequency power of heart rate variability correlate with cardiac sympathetic tone in normal sheep?”. Am J Physiol Heart Circ Physiol, 308(2), 2015:H148-9.

    2014

26. Cerri M., Del Vecchio F., Mastrotto M., Luppi M., Martelli D., Perez E., Tupone D., Zamboni G., Amici R. Enhanced Slow-Wave EEG Activity and Thermoregulatory Impairment following the Inhibition of the Lateral Hypothalamus in the Rat. Plos One, 9(11), 2014: e112849.
27. Martelli D., Yao S.T., Mancera J., McKinley M.J., McAllen R.M. Reflex control of inflammation by the splanchnic anti-inflammatory pathway is sustained and independent of anaesthesia. Am J Physiol Regul Int Comp Physiol, 307(9), 2014: R1085-91.
28. Martelli D., Silvani A., McAllen R.M., May C.N., Ramchandra R. The low frequency power of heart rate variability is neither a measure of cardiac sympathetic tone nor of baroreflex sensitivity. Am J Physiol Heart Circ Physiol, 307(7), 2014:H1005-12.
29. Martelli D., Yao S.T., McKinley M.J., McAllen R.M. Neural control of inflammation by the greater splanchnic nerves. Temperature, 2014 Epub: http://www.tandfonline.com/doi/full/10.4161/temp.29135
30. Martelli D., Yao S.T., McKinley M.J., McAllen R.M. Reflex control of inflammation by sympathetic nerves, not the vagus. J Physiol, 592, 2014:1677-1686.

    Note: This article has been recommended in F1000Prime (Faculty of 1000); Jänig W: F1000Prime Recommendation of [Martelli D et al., J Physiol (Lond) 2014]. In F1000Prime, 06 Feb 2014;

    DOI: 10.3410/f.718236549.793490418. F1000Prime.com/718236549#eval793490418.

    Note: This article was the editor’s choice of the published issue.

31. Martelli D., Luppi M., Cerri M., Tupone D., Perez E., Zamboni G., Amici R. The Direct Cooling of the Preoptic-Hypothalamic Area Elicits the Release of Thyroid Stimulating Hormone during Wakefulness but Not during REM Sleep. Plos One, 9(2), 2014: e87793.
32. Martelli D., McKinley M.J., McAllen R.M. The cholinergic anti-inflammatory pathway: a critical review. Auton Neurosci, 182, 2014:65-69.
33. Luppi M., Cerri M., Martelli D., Tupone D., Del Vecchio F., Di Cristoforo A., Perez E., Zamboni G., Amici R. Waking and sleeping in the rat made obese through a high-fat hypercaloric diet. Behav Brain Res, 258C, 2014:145-152.

    2013

34. Martelli D., Stanic D., Dutschman M. The emerging role of the parabrachial complex in the generation of wakefulness drive and its implication for respiratory control. Respir Physiol Neurobiol, 188(3) 2013: 318-23.
35. Cerri M., Mastrotto M., Tupone D., Martelli D., Luppi M., Perez E., Zamboni G., Amici R. The inhibition of neurons in the central nervous pathways for thermoregulatory cold defense induces a suspended animation state in the rat. J Neuroscience, 33(7), 2013: 2984-93.

    2012

36. Martelli D., Luppi M., Cerri M., Tupone D., Perez E., Zamboni G., Amici R. Waking and sleeping following water deprivation in the rat. Plos One, 7(9), 2012:e46116.
37. *Bratton B.O., *Martelli D., McKinley M.J., Trevaks D., Anderson C.R. and McAllen R.M.. Neural regulation of inflammation: no neural connection from the vagus to splenic sympathetic neurons. Exp Physiol, 97(11), 2012: 1180-5.

    Note: This article was the topic of an editorial; Exp Physiol. 2012 Nov;97(11):1178-9. doi: 10.1113/expphysiol.2011.064071. The inflammatory reflex: the current model should be revised. Romanovsky AA.

    2010

38. Luppi M., Martelli D., Amici R., Baracchi F., Cerri M, Dentico D., Perez E., Zamboni G. Hypothalamic osmoregulation is maintained across the wake-sleep cycle in the rat. J Sleep Res, 19(3), 2010: 394-399.
39. Cerri M., Zamboni G., Tupone D., Dentico D., Luppi M., Martelli D., Perez E., Amici R. Cutaneous vasodilation elicited by disinhibition of the caudal portion of the rostral ventromedial medulla of the free-behaving rat. Neuroscience, 165 (3), 2010: 984 995.

    2009

40. Dentico D., Amici R., Baracchi F., Cerri M., Luppi M., Martelli D., Perez E., Zamboni G. c-Fos expression in preoptic nuclei as a marker of sleep rebound in the rat. Eur J Neuroscience, 3 (4), 2009: 651-661.

TEXTBOOKS

2023

1. McAllen R.M., McKinley M.J., Martelli D. The autonomic inflammatory reflex. In “Primer on the Autonomic Nervous System, 4^th Edition” by I. Biaggioni, K. Browning, G. Fink, J. Jordan, P.A. Low, J. Paton. 2023: 341-344.

   2022

2. Martelli D. Controllo vegetativo della risposta immunitaria. Fisiologia Umana (seconda edizione) a cura di Francesca Grassi, Daniela Negrini, Carlo Adolfo Porro, Michele Zoli, Paola Borroni e Gabriella Cerri. Poletto Editore. 2022: 471-474 (in Italian).

   2021

3. Martelli D. Translator for the Italian edition of the Netter’s Essential Physiology, 2nd Edition of Susan E. Mulroney and Adam K. Myers. Piccin Editore. 2021 (in Italian).

TEACHING

Academic year 2022/23:

• Neurophysiology (Neuroanatomy and Neurophysiology I.C.) – School of Medicine and Surgery, Bachelor in Physiotherapy. University of Bologna. 36 hours
• Physiology (Signaling Pathways in Health and Disease I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. Teaching in English. 32 hours.
• Applied Physiology (Systems Physiology I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. 34 hours.
• Physiology -Specialisation Medical School of Cardiac Surgery, University of Bologna. 8 hours.
• Physiology -Specialisation Medical School of Vascular Surgery, University of Bologna. 8 hours.
• Physiology -Specialisation Medical School of Thoracic Surgery, University of Bologna. 8 hours.
• Physiology of the Upper and Lower Urinary Tract - Master in Pediatric Urology, University of Bologna. 2 hours

  Academic year 2021/22:

• Neurophysiology (Neuroanatomy and Neurophysiology I.C.) – School of Medicine and Surgery, Bachelor in Physiotherapy. University of Bologna. 36 hours
• Physiology (Signaling Pathways in Health and Disease C.I.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. Teaching in English. 32 hours.
• Physiology of the Upper and Lower Urinary Tract - Master in Pediatric Urology, University of Bologna. 2 hours

  Academic year 2020/21:

• Neurophysiology (Neuroanatomy and Neurophysiology I.C.) – School of Medicine and Surgery, Bachelor in Physiotherapy. University of Bologna. 36 hours
• Physiology (Signaling Pathways in Health and Disease C.I.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. Teaching in English. 32 hours.
• Physiology of the Upper and Lower Urinary Tract - Master in Pediatric Urology, University of Bologna. 2 hours

  Academic year 2019/20:

• Neurophysiology (Neuroanatomy and Neurophysiology I.C.) – School of Medicine and Surgery, Bachelor in Physiotherapy. University of Bologna. 36 hours
• Physiology (Signaling Pathways in Health and Disease C.I.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. Teaching in English. 32 hours.
• Physiology of the Upper and Lower Urinary Tract - Master in Pediatric Urology, University of Bologna. 2 hours

  Academic year 2018/19:

• Physiology of Nervous System and Sensory Organs (Nervous System and Sensory Organs I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. Teaching in English. 24 hours.
• Physiology of Genito-Urinay and Reproductive Systems (Genito-Urinary and Reproductive Systems I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. Teaching in English. 24 hours.
• Physiology (Signaling Pathways in Health and Disease C.I.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. Teaching in English. 16 hours.

  Academic year 2017/18:

• Nutrition Physiology (Physiology I.C.) – School of Medicine and Surgery, Bachelor in Dietistic, University of Bologna. 24 hours.
• Applied Physiology (Physiology I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. 34 hours.
• Physiology - Specialisation Medical School of Cardiac Surgery, Vascular Surgery and Thoracic Surgery, University of Bologna. 8 hours (the course was held in September 2019).

  Academic year 2016/17:

• Nutrition Physiology (Physiology I.C.) – School of Medicine and Surgery, Bachelor in Dietistic, University of Bologna. 24 hours.
• Applied Physiology (Physiology I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. 34 hours.
• Physiology -Specialisation Medical School of Cardiac Surgery, Vascular Surgery and Thoracic Surgery, University of Bologna. 8 hours (the course was held in January 2018).

  Academic year 2015/16:

• Physiology (Physiology I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. 48 hours.
• Applied Physiology (Physiology I.C.) – School of Medicine and Surgery, Combined Bachelor and Master in Medicine and Surgery, University of Bologna. 18 hours.