Dr. Cristiana Caliceti was born in Bologna (Italy). In 2007 she graduated in Chemistry and Pharmaceutical Technologies at the University of Bologna and in 2011 she obtained the PhD degree in Biochemistry. Part of her research activity was conducted at the Department of Pharmacology of University of Illinois at Chicago (Chicago, Illinois, US) as visiting PhD student in the lab of Prof. Masuko Ushio-Fukai.
She won several post-doc fellows at the University of Ferrara, in the Department of Medical Sciences in the field of cardiovascular system, estrogens, Notch signalling and redox signalling. In September 2015 she became junior researcher in BioAnalytical Chemistry (Department of Chemistry “Giacomo Ciamician”, University of Bologna). In october 2019 she became senior researcher of Biochemistry ( Dept. of Biomedical and Neuromotor Sciences, University of Bologna). Part of her scientific activity involves the study of redox signalling and Notch pathway in cardiovascular system and solid tumors. Moreover, she is interested in the cellular and molecular activities of bioactive molecules and nutraceuticals to prevent high socially relevant diseases and to develop bioanalytical methods based on bio-chemiluminescence detection with applications in drug screening and diagnostics.
Author of 45 papers on referred journals in the fields of General Biochemistry, Applied Biochemistry and Bioanalytical Chemistry and more than 50 oral and poster presentations in national and international congresses. She won several awards of Italian Society of Biochemistry (SIB) and Federation of European Biochemical Societies (FEBS).
Strong background in molecular biology, cell cultures, spectroscopic techniques (spectrophotometry, fluorimetry and bio-chemiluminescence), microscopy, ELISA assays, electrophoresis and western blotting, radioisotopic techniques, gene silencing and overexpression, PCR and qReal Time-PCR, isolation and disassembly of caveolae / lipid raft, animal model experiments. Part of the experimental work is carrying out at "Centro Unificato di Ricerca Biomedica applicata (CRBA)" at Sant'Orsola Malpighi Hospital.
Currently she is Prinicpal Investigator in "Ricerca medica traslazionale e clinica 2022 - Fondazione Cassa di Risparmio di Bologna" grant, with a project titled "Early detection of Colon Cancer: 'gut microbiota - bile acids - Notch signalling' interactive axis".
She is also associate investigator in:
- Italian Space Agency (ASI) 2023 grant, titled "Biosensore multiparametrico per il monitoraggio di marcatori salivari di danno cardiaco in corso di volo umano spaziale GRAVICUORE".
- MIUR PRIN 2022 funded by the Ministero Della Salute (Italy) titled "BIO-WASTE PRODUCTS AS A SOURCE OF NUTRACEUTICALS TO TARGET THE COMMON TRAIT OF INFLAMMATION IN CANCER AND NEURODEGENERATION".
- Italian Association of Cancer Research (AIRC) 2020-2025 grant titled “Cancer risk in hookah smokers”.
She participates in several funded national and international projects:
- Associate Investigator in the Union Horizon 2020 Work programme, European Proteomics Infrastructure Consortium-Providing Access (EPIC-XS) grant titled “Multi-omics signature of endothelial dysfunction to predict mortality in COVID-19 patients”
- Principal Investigator in "Ricerca medica traslazionale e clinica 2020 - Fondazione Cassa di Risparmio di Bologna" grant, with a project titled "Study of highly predictive biomarkers for assessing the occurrence of colon-rectal cancer"
- Principal Investigator in "Alma Idea junior" grant, Alma Mater Studiorum, University of Bologna (2017) with a project titled "Studio di biomarcatori altamente predittivi e sviluppo di piattaforme bioanalitiche POC per la valutazione precoce dell’insorgenza del cancro del colon retto"
- Associate investigator in MIUR PRIN 2015 funded by the Ministero Della Salute (Italy) titled "Securing And Ensuring Sustainable Use Of Agriculture Waste, Co- And By-Products: An Integrated Analytical Approach Combining Mass Spectrometry With Health Effect-Based Biosensing".
- Associate investigator Programma Operativo Regionale – Fondo Europeo di Sviluppo Regionale (POR FESR Regione Emilia Romagna) 2015:
1) Valorizzazione sostenibile degli scarti della filiera vitivinicola per l'industria chimica e salutistica (VALSOVIT).
2) Alimentazione, sistema immunitario, microbioma e tratto gastrointestinale: i nuovi protagonisti del mantenimento della salute e della prevenzione delle malattie degenerative. Identificazione e valorizzazione di principi attivi contenuti nei vegetali per la formulazione di alimenti e integratori utili nelle malattie infiammatorie intestinali, nella malattia metabolica, nell’obesità e nelle sue complicanze.
- Associate investigator AGER (Fondazione in rete per la ricercar agroalimentare) 2016: Valorization of Italian OLive products through INnovative analytical tools (VIOLIN).
Cristiana Caliceti granted the National Scientific Qualification ASN for the role of Associate Professor of General Biochemistry (from 28/03/2018 to 28/03/2024) and Analytical Chemistry (from 06/09/2018 to 06/09/2024) by Italian Ministry of Education University and Research.
COLLABORATIONS:
- Prof. Roberto Ferrari- University of Ferrara, Chair of Cardiology, Sant’Anna Hospital (Ferrara, Italy)
- Prof. Paola Rizzo – University of Ferrara, Department of Morphology, Surgery and Experimental Medicine (Ferrara, Italy)
- Prof. Arrigo Cicero – University of Bologna, Internal Medicine Chair (S. Orsola-Malpighi University Hospital) and President of the Italian Nutraceutical Society (SINut)
- Prof. ssa Giovanna Gentilomi, Dott.ssa Francesca Bonvicini - University of Bologna, Department of Pharmacy and BioTechnology (Bologna, Italy)
- Dott.ssa Eleonora Pagnotta - CREA - Research Centre for Cereal and Industrial Crops (Bologna), Council for Agricultural Research and Agricultural Economy Analysis (Bologna, Italy)
- Prof. Antonio Pannuti, Cancer Research Center, University of Hawaii. Honolulu, United States
- Prof. Doron Shabat, School of chemistry, Tel-Aviv University (Tel-Aviv, Israel)
- Prof. Norifumi Urao, Department of Pharmacology, Upstate Medical University (Syracuse, NY US)
- Prof. Lucio Miele - Stanley Scott Cancer Center and Louisiana Cancer Research Consortium, LSU Health Sciences Center School of Medicine, Department of Genetics New Orleans, University of Missisipi
- Prof. Sylvia Daunert, Department of Biochemistry and Molecular Biology, University of Miami (Florida, US)
