Dissertation topics suggested by the teacher.
1) Diffusion weighted MRI for the Microstructural characterization of human brain
This thesis project will be conducted abroad in collaboration with the Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford (Prof. James Grist) at the Department of Radiology, Oxford University Hospitals NHS Trust (UK), and can be declined into several topics:
·Development of new approaches for generating synthetic Diffusion MRI
.Validation and application of a novel diffusion MRI protocol for mapping brain structural connectivity
2) Quantitative Imaging, Dosimetry & AI in Nuclear Medicine
This thesis project will be conducted abroad in collaboration with The Multimodal Imaging & Theranostics group (Prof. Johannes Tran-Gia) at the Department of Nuclear Medicine, University Hospital Würzburg (Germany) and can be declined into several topics:
· Quantitative SPECT/CT and PET/CT imaging and image analysis for targeted radionuclide therapy
· Dosimetry concepts in targeted radionuclide therapy (organ- and voxel-based approaches)
· AI-based methods for image enhancement, denoising, segmentation, or partial-volume correction
· Monte Carlo simulations and phantom studies for assessment of imaging accuracy and uncertainty
· Data analysis and modelling of time-activity curves and tracer kinetics
Students will be integrated into an active research environment with strong international collaborations and a focus on clinically relevant, quantitative imaging research.
Recent dissertations supervised by the teacher.
First cycle degree programmes dissertations
- A preliminary approach to FPGA-based acceleration of brain MR fingerprinting maps reconstruction
- Analisi delle proprietà passive di membrana ottenute tramite registrazioni in patch-clamp per la modellizzazione di una cellula di glioblastoma
- Correlation between cognitive scores and diffusion metrics describing the activity of brain's glymphatic system in patients with dementia
- Diagnosi precoce della malattia di Alzheimer: la Fisica ed il suo contributo
- Fondamenti fisici di PET e PET CT e le loro applicazioni nella diagnosi differenziale tra Parkinson e Parkinsonismi
- La PET: dal principio fisico alle nuove
frontiere applicative della J-PET
- Risonanza Magnetica nella Sclerosi Multipla: dalle tecniche convenzionali alle tecniche quantitative
- Standardizzazione dei protocolli di acquisizione ed analisi dei dati di imaging di risonanza magnetica pesata in diffusione in ambito neurologico
- Tecniche 4DCT nella gestione del moto respiratorio in SGRT
- Tecniche di deep learning per migliorare la risoluzione temporale di acquisizioni fMRI
- Validazione del modello di diffusione cerebrale NODDI-X tramite RM su un fantoccio con crossing fibers
Second cycle degree programmes dissertations
- A first step towards EPID-based in-vivo dosimetry: distinguishing plan-specific from generic deviations
- Combination of CT perfusion parameters to improve definition of brain ischemic core
- Development of new approaches for generating synthetic Diffusion Gradient Directions in Diffusion Tensor Imaging
- Exploratory research on the rapid neuroplastic effects of ketamine on healthy subjects using structural MRI analysis-a retrospective study
- il ruolo del mitocondrio nella formazione di “lipidi mobili” in cellule linfoblastoidi umane hut-78
- Microstructure-Weighted Connectomics: Validation and application of a novel diffusion MRI protocol for mapping brain structural connectivity
- Neural Correlates of Prior Information Integration in Perceptual Decision-Making: An EEG and TMS Study
- Principal component analysis and generalized eigenvector decomposition of the neurophysiology of auditory memory
- Tractography reconstruction to assess the effects of age on arcuate fasciculus, corticospinal tract and cingulum bundle
- Understanding the effects of Alzheimer's Disease in Brain Microstructure: a comparison study of models in diffusion MRI
Specialisation Schools dissertations
- Clinical and Physical Evaluation of Commercially Available Software for Automated Breast Density Assessment
- Development of a tractography-based Index of Tumor Invasiveness for personalized treatment
- Secondary dose calculation system for patient-specific QA: clinical implementation for complex VMAT and SBRT treatments
- Spatially Fractionated Radiotherapy (SFRT) in soft-tissue sarcomas: innovation and radiobiological implications
- total-body pet/ct enables substantial activity–time optimisation across clinical radiotracers
- χ-Separation for Quantitative Magnetic Susceptibility Mapping: Phantom Validation and In Vivo Applications
