Foto del docente

Barbara Monti

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/09 Physiology

Publications

De Simone A.; La Pietra V.; Betari N.; Petragnani N.; Conte M.; Daniele S.; Pietrobono D.; Martini C.; Petralla S.; Casadei R.; Davani L.; Frabetti F.; Russomanno P.; Novellino E.; Montanari S.; Tumiatti V.; Ballerini P.; Sarno F.; Nebbioso A.; Altucci L.; Monti B.; Andrisano V.; Milelli A., Correction: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease (ACS Medicinal Chemistry Letters (2019) 10: 4 (469−474) DOI: 10.1021/acsmedchemlett.8b00507), «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 1357 - 1357 [Scientific article]

Petralla S.; Pena-Altamira L.E.; Poeta E.; Massenzio F.; Virgili M.; Barile S.N.; Sbano L.; Profilo E.; Corricelli M.; Danese A.; Giorgi C.; Ostan R.; Capri M.; Pinton P.; Palmieri F.; Lasorsa F.M.; Monti B., Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2019, 20, pp. 4486 - 4514 [Scientific article]Open Access

Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolini M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A., Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 178, pp. 243 - 258 [Scientific article]Open Access

De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A., Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease., «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 469 - 474 [Scientific article]Open Access

Scheiner M.; Dolles D.; Gunesch S.; Hoffmann M.; Nabissi M.; Marinelli O.; Naldi M.; Bartolini M.; Petralla S.; Poeta E.; Monti B.; Falkeis C.; Vieth M.; Hubner H.; Gmeiner P.; Maitra R.; Maurice T.; Decker M., Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo, «JOURNAL OF MEDICINAL CHEMISTRY», 2019, 62, pp. 9078 - 9102 [Scientific article]Open Access

Romeiro L.A.S.; Da Costa Nunes J.L.; De Oliveira Miranda C.; Simoies Heyn Roth Cardoso G.; De Oliveira A.S.; Gandini A.; Kobrlova T.; Soukup O.; Rossi Michele.; Senger J.; Jung M.; Gervasoni S.; Vistoli G.; Petralla S.; Massenzio F.; Monti B.; Bolognesi M.L., Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease, «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 671 - 676 [Scientific article]

Chalupova K.; Korabecny J.; Bartolini M.; Monti B.; Lamba D.; Caliandro R.; Pesaresi A.; Brazzolotto X.; Gastellier A.-J.; Nachon F.; Pejchal J.; Jarosova M.; Hepnarova V.; Jun D.; Hrabinova M.; Dolezal R.; Zdarova Karasova J.; Mzik M.; Kristofikova Z.; Misik J.; Muckova L.; Jost P.; Soukup O.; Benkova M.; Setnicka V.; Habartova L.; Chvojkova M.; Kleteckova L.; Vales K.; Mezeiova E.; Uliassi E.; Valis M.; Nepovimova E.; Bolognesi M.L.; Kuca K., Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 168, pp. 491 - 514 [Scientific article]

Roldan-Pena J.M.; Romero-Real V.; Hicke J.; Maya I.; Franconetti A.; Lagunes I.; Padron J.M.; Petralla S.; Poeta E.; Naldi M.; Bartolini M.; Monti B.; Bolognesi M.; Lopez O.; Fernandez-Bolanos J.G., Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 181, Article number: 111550 , pp. 111550 - 111565 [Scientific article]

Giorgi, Gianfranco; Virgili, Marco; Monti, Barbara; Del Re, Brunella*, Long INterspersed nuclear Elements (LINEs) in brain and non-brain tissues of the rat, «CELL AND TISSUE RESEARCH», 2018, 374, pp. 17 - 24 [Scientific article]Open Access

Massenzio, Francesca; Peña-Altamira, Emiliano; Petralla, Sabrina; Virgili, Marco; Zuccheri, Giampaolo; Miti, Andrea; Polazzi, Elisabetta; Mengoni, Ilaria; Piffaretti, Deborah; Monti, Barbara*, Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose, «BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE», 2018, 1864, pp. 3771 - 3785 [Scientific article]

Peña-Altamira LE, Polazzi E, Giuliani P, Beraudi A, Massenzio F, Mengoni I, Poli A, Zuccarini M, Ciccarelli R, Di Iorio P, Virgili M, Monti B, Caciagli F., Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors., «NEUROCHEMISTRY INTERNATIONAL», 2018, 115, pp. 37 - 49 [Scientific article]

Gandini, Annachiara; Bartolini, Manuela; Tedesco, Daniele; Martinez-Gonzalez, Loreto; Roca, Carlos; Campillo, Nuria E.; Zaldivar-Diez, Josefa; Perez, Concepción; Zuccheri, Giampaolo; Miti, Andrea; Feoli, Alessandra; Castellano, Sabrina; Petralla, Sabrina; Monti, Barbara; Rossi, Martina; Moda, Fabio; Legname, Giuseppe; Martinez, Ana; Bolognesi, Maria Laura*, Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors, «JOURNAL OF MEDICINAL CHEMISTRY», 2018, 61, pp. 7640 - 7656 [Scientific article]

Profilo, E; Peña-Altamira, Le; Corricelli, M; Castegna, A; Danese, A; Agrimi, G; Petralla, S; Giannuzzi, G; Porcelli, V; Sbano, L; Viscomi, C; Massenzio, F; Palmieri, Em; Giorgi, C; Fiermonte, G; Virgili, M; Palmieri, L; Zeviani, M; Pinton, P; Monti, B; Palmieri, F; Lasorsa, Fm., Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells., «BIOCHIMICA ET BIOPHYSICA ACTA», 2017, 1863, pp. 1422 - 1435 [Scientific article]

Giuliani, P; Zuccarini, M; Buccella, S; Peña-Altamira, Le; Polazzi, E; Virgili, M; Monti, B; Poli, A; Rathbone, Mp; Di Iorio, P; Ciccarelli, R; Caciagli, F., Evidence for purine nucleoside phosphorylase (PNP) release from RAT C6 glioma cells., «JOURNAL OF NEUROCHEMISTRY», 2017, 141, pp. 208 - 221 [Scientific article]

Roldán-Peña, Jesús M.; Alejandre-Ramos, Daniel; López, O“scar; Maya, Inés; Lagunes, Irene; Padrón, José M.; Peña-Altamira, Luis Emiliano; Bartolini, Manuela; Monti, Barbara; Bolognesi, Maria L.; Fernández-Bolaños, José G., New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 138, pp. 761 - 773 [Scientific article]Open Access

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