Foto del docente

Anna Maria Porcelli

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/10 Biochemistry


Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM, A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function, «CANCER RESEARCH», 2011, 71, pp. 6220 - 6229 [Scientific article]

G. Gasparre; G. Romeo; M. Rugolo; A.M. Porcelli, Learning from oncocytic tumors: why choose inefficient mitochondria?, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS», 2011, 1807 (6), pp. 633 - 642 [Scientific article]

A.M.Porcelli ;A. Ghelli ;C. Ceccarelli ;M. Lang ;G. Cenacchi ; M.Capristo ;L.F. Pennisi ; I.Morra; E.Ciccarelli ; A.Melcarne ; A.;Bartoletti-Stella; N .Salfi ; G.Tallini ; A.Martinuzzi ; V.Carelli ; M.Attimonelli ; M.Rugolo ;G. Romeo ; G.Gasparre ., The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization, «HUMAN MOLECULAR GENETICS», 2010, 19 (issue 6), pp. 1019 - 1032 [Scientific article]

Capodicasa S.; Fedi S.; Porcelli A.M.; Zannoni D., The microbial community dwelling on a biodeteriorated 16th century painting, «INTERNATIONAL BIODETERIORATION & BIODEGRADATION», 2010, 64, pp. 727 - 733 [Scientific article]

G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli., An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells., «HUMAN MUTATION», 2009, 30 (3), pp. 391 - 396 [Scientific article]

A. M. Porcelli; A. Angelin; A. Ghelli; E. Mariani; A. Martinuzzi; V. Carelli; V. Petronilli; P. Bernardi; M. Rugolo, Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels, «THE JOURNAL OF BIOLOGICAL CHEMISTRY», 2009, 284, pp. 2045 - 2052 [Scientific article]

Ghelli A.; Porcelli A.M.; Zanna C.; Vidoni S.; Mattioli S.; Barbieri A.; Iommarini L.; Pala M.; Achilli A.; Torroni A.; Rugolo M.; Carelli V., The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity., «PLOS ONE», 2009, 4, Article number: e7922 , pp. 1 - 11 [Scientific article]Open Access

Zanna C.; Ghelli A.; Porcelli A.M.; Karbowski M.; Youle R.J.; Schimpf S.; Wissinger B.; Pinti M.; Cossarizza A.; Vidoni S.; Valentino M.L.; Rugolo M.; Carelli V., OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion., «BRAIN», 2008, 131, pp. 352 - 367 [Scientific article]

Ghelli A.; Porcelli A.M.; Zanna C.; Martinuzzi A.; Carelli V.; Rugolo M., Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids., «INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE», 2008, 49, pp. 671 - 676 [Scientific article]

Coordination of a Research Project: Role of mitochondria in the regulation of apoptosis and autophagy: molecular mechanisms and effects of pathogenic mutations”..

Porcelli A.M.; Ghelli A.; Iommarini L.; Mariani E.; Hoque M.; Zanna C.; Gasparre G.; Rugolo M., The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I., «CELLULAR AND MOLECULAR LIFE SCIENCES», 2008, 65, pp. 2943 - 2951 [Scientific article]

Gasparre G.; Porcelli A.M.; Bonora E.; Pennisi L.F.; Toller M.; Iommarini L.; Ghelli A.; Moretti M.; Betts C.M.; Martinelli G.N.; Ceroni A.R.; Curcio F.; Carelli V.; Rugolo M.; Tallini G.; Romeo G., Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours., «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2007, 104, pp. 9001 - 9006 [Scientific article]

BONORA E.; PORCELLI A.M.; GASPARRE G.; BIONDI A.; GHELLI A.; CARELLI V.; BARACCA A.; TALLINI G.; MARTINUZZI A.; LENAZ G.; RUGOLO M.; ROMEO G., Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III, «CANCER RESEARCH», 2006, 66, pp. 6087 - 6096 [Scientific article]

ZANNA C.; GHELLI A.; PORCELLI AM.; MARTINUZZI A.; Carelli V.; RUGOLO M., Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G., «APOPTOSIS», 2005, 10, pp. 997 - 1007 [Scientific article]

A. M.PORCELLI; A. GHELLI; C. ZANNA; P. PINTON; R. RIZZUTO; M.RUGOLO, pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant, «BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS», 2005, 326, pp. 779 - 804 [Scientific article]

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