Foto del docente

Anna Maria Porcelli

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/10 Biochemistry

Publications

Mancini C;Roncaglia P;Brussino A;Stevanin G;Lo Buono N;Krmac H;Maltecca F;Gazzano E;Bartoletti Stella A;Calvaruso MA;Iommarini L;Cagnoli C;Forlani S;Le Ber I;Durr A;Brice A;Ghigo D;Casari G;Porcelli AM;Funaro A;Gasparre G;Gustincich S;Brusco A, Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways., «BMC MEDICAL GENOMICS», 2013, 6, pp. 22 - 32 [Scientific article]Open Access

Coordination of a Research Project: JANEUTICS - From the oncojanus function of mitochondrial genes to anti-cancer therapeutics strategies.

G. Gasparre; A.M. Porcelli; G. Lenaz; G. Romeo, Relevance of Mitochondrial Genetics and Metabolism in Cancer Development, «COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY», 2013, 5(2), pp. 1 - 17 [Scientific article]

Calabrese C.; Iommarini L.; Kurelac I.; Calvaruso M.A.; Capristo M.; Lollini P.L.; Nanni P.; Bergamini C.; Nicoletti G.; De Giovanni C.; Ghelli A.; Giorgio V.; Caratozzolo M.F.; Marzano F.; Manzari C.; Betts C.M.; Carelli V.; Ceccarelli C.; Attimonelli M.; Romeo G.; Fato R.; Rugolo M.; Tullo A.; Gasparre G.; Porcelli A.M., Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells, «CANCER & METABOLISM», 2013, 1, Article number: 11 , pp. 1 - 15 [Scientific article]Open Access

Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; De Nardo V.; Martinuzzi A.; Wibrand F.; Vissing J.; Kurelac I.; Gasparre G.; Selamoglu N.; Daldal F.; Rugolo M., The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes, «HUMAN MOLECULAR GENETICS», 2013, 22, pp. 2141 - 2151 [Scientific article]

P. Angelini; C. Bergamini ; K. J. Rhoden;R. Fato; A. M. Porcelli; G. Zuccheri, Towards triplex-based intracellular pH biosensors based on self-assembled DNA nanostructures, in: Nanoscience Institute 2 nd Workshop, Modena, Istituto Nanoscienze CNR, 2013, pp. 62 - 62 (atti di: II Workshop of the Istituto Nanoscienze, Modena, Italia, 10-11/06/2013) [Abstract]

Petruzzella V.; Carrozzo R.; Calabrese C.; Dell'aglio R.; Trentadue R.; Piredda R.; Artuso L.; Rizza T.; Bianchi M.; Porcelli A.M.; Guerriero S.; Gasparre G.; Attimonelli M., Deep sequencing unearths Nuclear mitochondrial Sequences under Leber's hereditary optic neuropathy-associated false heteroplasmic mitochondrial DNA variants., «HUMAN MOLECULAR GENETICS», 2012, 21(17), pp. 3753 - 3764 [Scientific article]

Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM, A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function, «CANCER RESEARCH», 2011, 71, pp. 6220 - 6229 [Scientific article]

G. Gasparre; G. Romeo; M. Rugolo; A.M. Porcelli, Learning from oncocytic tumors: why choose inefficient mitochondria?, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS», 2011, 1807 (6), pp. 633 - 642 [Scientific article]

A.M.Porcelli ;A. Ghelli ;C. Ceccarelli ;M. Lang ;G. Cenacchi ; M.Capristo ;L.F. Pennisi ; I.Morra; E.Ciccarelli ; A.Melcarne ; A.;Bartoletti-Stella; N .Salfi ; G.Tallini ; A.Martinuzzi ; V.Carelli ; M.Attimonelli ; M.Rugolo ;G. Romeo ; G.Gasparre ., The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization, «HUMAN MOLECULAR GENETICS», 2010, 19 (issue 6), pp. 1019 - 1032 [Scientific article]

Capodicasa S.; Fedi S.; Porcelli A.M.; Zannoni D., The microbial community dwelling on a biodeteriorated 16th century painting, «INTERNATIONAL BIODETERIORATION & BIODEGRADATION», 2010, 64, pp. 727 - 733 [Scientific article]

G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli., An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells., «HUMAN MUTATION», 2009, 30 (3), pp. 391 - 396 [Scientific article]

A. M. Porcelli; A. Angelin; A. Ghelli; E. Mariani; A. Martinuzzi; V. Carelli; V. Petronilli; P. Bernardi; M. Rugolo, Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels, «THE JOURNAL OF BIOLOGICAL CHEMISTRY», 2009, 284, pp. 2045 - 2052 [Scientific article]

Ghelli A.; Porcelli A.M.; Zanna C.; Vidoni S.; Mattioli S.; Barbieri A.; Iommarini L.; Pala M.; Achilli A.; Torroni A.; Rugolo M.; Carelli V., The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity., «PLOS ONE», 2009, 4, Article number: e7922 , pp. 1 - 11 [Scientific article]Open Access

Zanna C.; Ghelli A.; Porcelli A.M.; Karbowski M.; Youle R.J.; Schimpf S.; Wissinger B.; Pinti M.; Cossarizza A.; Vidoni S.; Valentino M.L.; Rugolo M.; Carelli V., OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion., «BRAIN», 2008, 131, pp. 352 - 367 [Scientific article]

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