Dynamic processes of
enantiomerization, ring inversion, bond rotation and others that
can be observed by variable temperature NMR in solution or in the
solid state (CP-MAS Dynamic NMR).
Computer
calculation (Molecular Mechanics or ab-initio methods), to
determine the conformation of molecules in their low-energy
state,
Use of cryogenic
enantioselective HPLC for the separation of conformational
enantiomers (in collaboration with Prof. Gasparrini, Univ.”La
Sapienza”, Rome)
Use of X-ray
diffraction for the structure determination of the molecular
conformation in the solid state, and comparision with solid state
NMR.
Determination of
the absolute configuration of organic molecules by chiroptical
methods (ECD, VCD and OR) and DFT calculations.
