Fornari F.; Milazzo M.; Chieco P.; Negrini M.; Marasco E.; Capranico G.; Mantovani V.; Marinello J.; Sabbioni S.; Callegari E.; Cescon M.; Ravaioli M.; Croce C.M.; Bolondi L.; Gramantieri L., In hepatocellular carcinoma miR-519d is up-regulated by p53 and
DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2., «JOURNAL OF PATHOLOGY», 2012, 227, pp. 275 - 285 [Scientific article]
Manzo S. G.; Z.-L. Zhou; Y.-Q. Wang; J. Marinello; J.-X. He; Y.-C. Li; J. Ding; G. Capranico; Z.-H. Miao, Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II, «CANCER RESEARCH», 2012, 72, pp. 5363 - 5373 [Scientific article]
I D'Annessa; C Tesauro; P Fiorani; G Chillemi; S Castelli; O Vassallo; G Capranico; A Desideri, Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin, «JOURNAL OF AMINO ACIDS», 2012, 2012, pp. 1 - 8 [Scientific article]
Capranico G; Baranello L; Bertozzi D; Marinello J, Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity, in: DNA Topoisomerases and Cancer, NEW YORK, Humana Press - Springer Science, 2012, pp. 309 - 324 (CANCER DRUG DISCOVERY AND DEVELOPMENT) [Chapter or essay]
Bertozzi Davide; Iurlaro Raffaella; Sordet Olivier; Marinello Jessica; Zaffaroni Nadia; Capranico Giovanni, Characterization of novel antisense HIF-1α transcripts in human cancers, «CELL CYCLE», 2011, 10, pp. 3189 - 3197 [Scientific article]
Ricci A; Marinello J; Bortolus M; Sanchez A; Grandas A; Pedroso E; Pommier Y; Capranico G; Maniero AL; Zagotto G., Electron Paramagnetic Resonance (EPR) Study of Spin-Labeled Camptothecin Derivatives: A Different Look of the Ternary Complex., «JOURNAL OF MEDICINAL CHEMISTRY», 2011, 54, pp. 1003 - 1009 [Scientific article]
G. Capranico; J. Marinello; L. Baranello, Dissecting the transcriptional
functions of human DNA topoisomerase I by selective inhibitors: Implications for
physiological and therapeutic modulation of enzyme activity., «BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER», 2010, 1806(2), pp. 240 - 250 [Scientific article]
L. Baranello; D. Bertozzi; M.V. Fogli; Y. Pommier; G. Capranico, DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1a gene locus., «NUCLEIC ACIDS RESEARCH», 2010, 38, pp. 159 - 171 [Scientific article]
Lotito L.; Russo A.; Bueno S.; Chillemi G.; Fogli M.V.; Capranico G., A specific transcriptional response of yeast cells to camptothecin dependent on the Swi4 and Mbp1 factors., «EUROPEAN JOURNAL OF PHARMACOLOGY», 2009, 603, pp. 29 - 36 [Scientific article]
Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello J; Capranico G; Zini M; Stefanelli C; Melchiorre C, DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT, «JOURNAL OF MEDICINAL CHEMISTRY», 2009, 52, pp. 7873 - 7877 [Scientific article]
Filosa R.; Peduto A.; Micco S.D.; Caprariis P.D.; Festa M.; Petrella A.; Capranico G.; Bifulco G., Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors., «BIOORGANIC & MEDICINAL CHEMISTRY», 2009, 17, pp. 13 - 24 [Scientific article]
Lotito L.; Russo A.; Chillemi G.; Bueno S.; Cavalieri D.; Capranico G., Global transcription regulation by DNA topoisomerase I in exponentially growing Saccharomyces cerevisiae cells: Activation of telomere-proximal genes by TOP1 deletion, «JOURNAL OF MOLECULAR BIOLOGY», 2008, 377, pp. 311 - 322 [Scientific article]
Dal Ben D.; Palumbo M.; Zagotto G.; Capranico G.; Moro S., DNA Topoisomerase II Structures and Anthracycline Activity: Insights into Ternary Complex Formation., «CURRENT PHARMACEUTICAL DESIGN», 2007, 13, pp. 2766 - 2780 [Scientific article]
Capranico G.; Ferri F.; Fogli M.V.; Russo A.; Lotito L.; Baranello L., The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I., «BIOCHIMIE», 2007, 89, pp. 482 - 489 [Scientific article]
Khobta A; Ferri F; Lotito L; Montecucco A; Rossi R; Capranico G, Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cells., «JOURNAL OF MOLECULAR BIOLOGY», 2006, 357, pp. 127 - 138 [Scientific article]
