Simona Soverini

Tesi di Laurea Magistrale

• Bone marrow niche–driven AXL and HES1 signaling in FLT3-ITD Acute Myeloid Leukemia persistence
• Bone Marrow Vessel-On-Chip To Study Leukaemia-Endothelium Dynamics
• Epigenetic dysregulation, genetic instability and metabolic reprogramming in Chronic Myeloid Leukemia: the impact of SETD2 loss
• Identification and characterization of three novel soluble factors in a model of pediatric Acute Myeloid Leukemia bone marrow niche.
• The effects of PRIMPOL silencing in SF3B1 and SRSF2 mutated primary erythroblasts: an analysis on cell cycle and cellular differentiation