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Nicola Baldini

Professore ordinario

Dipartimento di Scienze Biomediche e Neuromotorie

Settore scientifico disciplinare: MED/50 SCIENZE TECNICHE MEDICHE APPLICATE

Pubblicazioni

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Pubblicazioni antecedenti il 2004

- Sanchez-Carbayo M, Belbin TJ, Scotlandi K, Prystowsky M, Baldini N, Childs G, Cordon-Cardo C: Expression profiling of osteosarcoma cells transfected with MDR1 and NEO genes: regulation of cell adhesion, apoptosis, and tumor suppression-related genes. 83(4):507-17. Lab Invest. 2003

- Granchi D, Savarino L, Ciapetti G, Cenni E, Rotini R, Mieti M, Baldini N, Giunti A: Immunological changes in patients with primary osteoarthritis of the hip after total joint replacement. 85(5):758-64. J Bone Joint Surg Br. 2003

- Savarino L, Granchi D, Ciapetti G, Cenni E, Greco M, Rotini R, Veronesi CA, Baldini N, Giunti A: Ion release in stable hip arthroplasties using metal-on-metal articulating surfaces: a comparison between short- and medium-term results. 66(3):450-6. J Biomed Mater Res A. 2003

- Savarino L, Fini M, Ciapetti G, Cenni E, Granchi D, Baldini N, Greco M, Rizzi G, Giardino R, Giunti A: Biologic effects of surface roughness and fluorhydroxyapatite coating on osteointegration in external fixation systems: an in vivo experimental study. 66(3):652-61. J Biomed Mater Res A. 2003

- Ronda N, Bernini F, Giacosa R, Gatti R, Baldini N, Buzio C, Orlandini G: Normal human IgG prevents endothelial cell activation induced by TNFalpha and oxidized low-density lipoprotein atherogenic stimuli. 133(2):219-26. Clin Exp Immunol. 2003

- Ciapetti G, Ambrosio L, Savarino L, Granchi D, Cenni E, Baldini N, Pagani S, Guizzardi S, Causa F, Giunti A: Osteoblast growth and function in porous poly epsilon -caprolactone matrices for bone repair: a preliminary study. 24(21):3815-24. Biomaterials. 2003

- Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y: Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells. 21(8):1295-8. Oncogene. 2002

- Savarino L, Granchi D, Ciapetti G, Cenni E, Nardi Pantoli A, Rotini R, Veronesi CA, Baldini N, Giunti A: Ion release in patients with metal-on-metal hip bearings in total joint replacement: a comparison with metal-on-polyethylene bearings. 63(5):467-74. J Biomed Mater Res. 2002

- Granchi D, Stea S, Sudanese A, Toni A, Baldini N, Giunti A: Association of two gene polymorphisms with osteoarthritis secondary to hip dysplasia. (403):108-17. Clin Orthop Relat Res. 2002

- Scotlandi K, Maini C, Manara MC, Benini S, Serra M, Cerisano V, Strammiello R, Baldini N, Lollini PL, Nanni P, Nicoletti G, Picci P: Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells. 9(3):296-307. Cancer Gene Ther. 2002

- Granchi D, Ciapetti G, Savarino L, Cenni E, Pizzoferrato A, Baldini N, Giunti A: Effects of bone cement extracts on the cell-mediated immune response. 23(4):1033-41. Biomaterials. 2002

- Benini S, Manara MC, Baldini N, Cerisano V, Massimo Serra, Mercuri M, Lollini PL, Nanni P, Picci P, Scotlandi K: Inhibition of insulin-like growth factor I receptor increases the antitumor activity of doxorubicin and vincristine against Ewing's sarcoma cells. 7(6):1790-7. Clin Cancer Res. 2001

- Granchi D, Cenni E, Savarino L, Ciapetti G, Forbicini G, Vancini M, Maini C, Baldini N, Giunti A: Bone cement extracts modulate the osteoprotegerin/osteoprotegerin-ligand expression in MG63 osteoblast-like cells. 23(11):2359-65. 2000

- Ciapetti G, Granchi D, Savarino L, Cenni E, Magrini E, Baldini N, Giunti A: In vitro testing of the potential for orthopedic bone cements to cause apoptosis of osteoblast-like cells. 23(2):617-27. Biomaterials. 2002

- Scotlandi K, Benini S, Manara MC, Serra M, Nanni P, Lollini PL, Nicoletti G, Landuzzi L, Chano T, Picci P, Baldini N: Murine model for skeletal metastases of Ewing's sarcoma. 18(6):959-66. J Orthop Res. 2000

- Ferracini R, Scotlandi K, Cagliero E, Acquarone F, Olivero M, Wunder J, Baldini N: The expression of Met/hepatocyte growth factor receptor gene in giant cell tumors of bone and other benign musculoskeletal tumors. 184(2):191-6. J Cell Physiol. 2000

- Scotlandi K, Chano T, Benini S, Serra M, Manara MC, Cerisano V, Picci P, Baldini N: Identification of EWS/FLI-1 transcripts in giant-cell tumor of bone. 87(3):328-35. Int J Cancer. 2000

- Scotlandi K, Baldini N, Cerisano V, Manara MC, Benini S, Serra M, Lollini PL, Nanni P, Nicoletti G, Bernard G, Bernard A, Picci P: CD99 engagement: an effective therapeutic strategy for Ewing tumors. 60(18):5134-42. Cancer Res. 2000

- Manara MC, Baldini N, Serra M, Lollini PL, De Giovanni C, Vaccari M, Argnani A, Benini S, Maurici D, Picci P, Scotlandi K: Reversal of malignant phenotype in human osteosarcoma cells transduced with the alkaline phosphatase gene. 26(3):215-20. Bone. 2000

- Bacci G, Di Fiore M, Rimondini S, Baldini N: Delayed diagnosis and tumor stage in Ewing's sarcoma. 6(2):465-6. Oncol Rep. 1999

- Scotlandi K, Manara MC, Serra M, Benini S, Maurici D, Caputo A, De Giovanni C, Lollini PL, Nanni P, Picci P, Campanacci M, Baldini N: The expression of P-glycoprotein is causally related to a less aggressive phenotype in human osteosarcoma cells. 18(3):739-46. Oncogene. 1999

- Baldini N, Scotlandi K, Serra M, Picci P, Bacci G, Sottili S, Campanacci M: P-glycoprotein expression in osteosarcoma: a basis for risk-adapted adjuvant chemotherapy. 17(5):629-32. J Orthop Res. 1999

- Serra M, Maurici D, Scotlandi K, Barbanti-Brodano G, Manara MC, Benini S, Picci P, Bertoni F, Bacci G, Sottili S, Baldini N: Relationship between P-glycoprotein expression and p53 status in high-grade osteosarcoma. 14(2):301-7. Int J Oncol. 1999

- Picci P, Sudanese A, Greggi T, Baldini N: Intramuscular hemangioma in infancy: diagnostic and therapeutic considerations. 9(1):72-5. J Pediatr Orthop. 1999

- Picci P, Sudanese A, Greggi T, Baldini N: Intramuscular hemangioma in infancy: diagnostic and therapeutic considerations. 9(1):72-5. J Pediatr Orthop. 1999

- Benini S, Baldini N, Manara MC, Chano T, Serra M, Rizzi S, Lollini PL, Picci P, Scotlandi K: Redundancy of autocrine loops in human osteosarcoma cells. 80(4):581-8. Int J Cancer. 1999

- Farabegoli F, Ceccarelli C, Santini D, Baldini N, Taffurelli M, Marrano D, Treré D, Derenzini M: c-erbB-2 over-expression in amplified and non-amplified breast carcinoma samples. 84(3):273-7. Int J Cancer. 1999

- Maraldi NM, Zini N, Santi S, Scotlandi K, Serra M, Baldini N: P-glycoprotein subcellular localization and cell morphotype in MDR1 gene-transfected human osteosarcoma cells. 91(1):17-28. Biol Cell. 1999

- Lollini PL, Landuzzi L, Frabetti F, Rossi I, Nicoletti G, Scotlandi K, Serra M, Baldini N, De Giovanni C, Nanni P: Expression of functional CD40 on human osteosarcoma and Ewing's sarcoma cells. 4(8):1843-9.Clin Cancer Res. 1998

- Scotlandi K, Benini S, Nanni P, Lollini PL, Nicoletti G, Landuzzi L, Serra M, Manara MC, Picci P, Baldini N: Blockage of insulin-like growth factor-I receptor inhibits the growth of Ewing's sarcoma in athymic mice. 58(18):4127-31. Cancer Res. 1998

- Maurici D, Perez-Atayde A, Grier HE, Baldini N, Serra M, Fletcher JA: Frequency and implications of chromosome 8 and 12 gains in Ewing sarcoma. 100(2):106-10. Cancer Genet Cytogenet. 1998

- Bacci G, Picci P, Mercuri M, Ferrari S, Longhi A, Cesari M, Rosito P, Mancini AF, Barbieri E, Baldini N: Predictive factors of histological response to primary chemotherapy in Ewing's sarcoma. 37(7-8):671-6. Acta Oncol. 1998

- Baldini N: Multidrug resistance--a multiplex phenomenon. 3(4):378-80. Nat Med. 1997

- Zini N, Neri LM, Ognibene A, Scotlandi K, Baldini N, Maraldi NM: Increase of nuclear phosphatidylinositol 4,5-bisphosphate and phospholipase C beta 1 is not associated to variations of protein kinase C in multidrug-resistant Saos-2 cells. 36(3):172-8. Microsc Res Tech. 1997

- Lollini PL, Palmieri G, De Giovanni C, Landuzzi L, Nicoletti G, Rossi I, Griffoni C, Frabetti F, Scotlandi K, Benini S, Baldini N, Santoni A, Nanni P: Expression of interleukin 15 (IL-15) in human rhabdomyosarcoma, osteosarcoma and Ewing's sarcoma. 71(5):732-6. Int J Cancer. 1997

- Gasbarrini A, Grigolo B, Serra M, Baldini N, Scotlandi K, Gasbarrini A, Bernardi M, Facchini A: Generation of free radicals during anoxia and reoxygenation in perfused osteoblastlike cells. (338):247-52. Clin Orthop Relat Res. 1997

- Farabegoli F, Ceccarelli C, Santini D, Trerè D, Baldini N, Taffurelli M, Derenzini M: Chromosome 1 aneusomy with 1p36 under-representation is related to histologic grade, DNA aneuploidy, high c-erb B-2 and loss of bcl-2 expression in ductal breast carcinoma. 69(5):381-5. Int J Cancer. 1996

- Scotlandi K, Serra M, Manara MC, Benini S, Sarti M, Maurici D, Lollini PL, Picci P, Bertoni F, Baldini N: Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor. 27(4):408-16. Hum Pathol. 1996

- Zini N, Ognibene A, Bavelloni A, Santi S, Sabatelli P, Baldini N, Scotlandi K, Serra M, Maraldi NM: Cytoplasmic and nuclear localization sites of phosphatidylinositol 3-kinase in human osteosarcoma sensitive and multidrug-resistant Saos-2 cells. 106(5):457-64. Histochem Cell Biol. 1996

- Serra M, Scotlandi K, Manara MC, Maurici D, Benini S, Sarti M, Nini G, Barbanti-Brodano G, Baldini N: Evaluation of P-glycoprotein expression in soft tissue sarcomas of the extremities. 19(3):253-6. Cytotechnology. 1996

- Scotlandi K, Serra M, Nicoletti G, Vaccari M, Manara MC, Nini G, Landuzzi L, Colacci A, Bacci G, Bertoni F, Picci P, Campanacci M, Baldini N: Multidrug resistance and malignancy in human osteosarcoma. 56(10):2434-9. Cancer Res. 1996

- Scotlandi K, Benini S, Sarti M, Serra M, Lollini PL, Maurici D, Picci P, Manara MC, Baldini N: Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: a possible therapeutic target. 56(20):4570-4. Cancer Res. 1996

- Scotlandi K, Baldini N, Oliviero M, Di Renzo MF, Martano M, Serra M, Manara MC, Comoglio PM, Ferracini R: Expression of Met/hepatocyte growth factor receptor gene and malignant behavior of musculoskeletal tumors. 149(4):1209-19. Am J Pathol. 1996

- Ferracini R, Di Renzo MF, Scotlandi K, Baldini N, Olivero M, Lollini P, Cremona O, Campanacci M, Comoglio PM: The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit. 10(4):739-49. Oncogene. 1995

- Baldini N, Scotlandi K, Barbanti-Bròdano G, Manara MC, Maurici D, Bacci G, Bertoni F, Picci P, Sottili S, Campanacci M, et al: Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome. 333(21):1380-5. N Engl J Med. 1995

- Baldini N, Scotlandi K, Serra M, Shikita T, Zini N, Ognibene A, Santi S, Ferracini R, Maraldi NM: Nuclear immunolocalization of P-glycoprotein in multidrug-resistant cell lines showing similar mechanisms of doxorubicin distribution. 68(3):226-39. Eur J Cell Biol. 1995

- Serra M, Scotlandi K, Manara MC, Maurici D, Benini S, Sarti M, Campanacci M, Baldini N: Analysis of P-glycoprotein expression in osteosarcoma. 31A(12):1998-2002. Eur J Cancer. 1995

- Scotlandi K, Serra M, Manara MC, Maurici D, Benini S, Nini G, Campanacci M, Baldini N: Clinical relevance of Ki-67 expression in bone tumors. 75(3):806-14. Cancer. 1995

- Zini N, Scotlandi K, Baldini N, Nini G, Sabatelli P, Maraldi N: Multidrug-resistance (MDR) phenotype of human osteosarcoma cells evaluated by quantitative morphological and electron microscopy analyses. 84(3):195-204. Biol Cell.  1995

- De Mattei M, Martini F, Tognon M, Serra M, Baldini N, Barbanti-Brodano G: Polyomavirus latency and human tumors. 169(5):1175-6. J Infect Dis. 1994

- Chenu C, Colucci S, Grano M, Zigrino P, Barattolo R, Zambonin G, Baldini N, Vergnaud P, Delmas PD, Zallone AZ: Osteocalcin induces chemotaxis, secretion of matrix proteins, and calcium-mediated intracellular signaling in human osteoclast-like cells. 127(4):1149-58. J Cell Biol. 1994

- Scotlandi K, Serra M, Manara MC, Lollini PL, Maurici D, Del Bufalo D, Baldini N: Pre-treatment of human osteosarcoma cells with N-methylformamide enhances P-glycoprotein expression and resistance to doxorubicin. 58(1):95-101. Int J Cancer. 1994

- Grano M, Zigrino P, Colucci S, Zambonin G, Trusolino L, Serra M, Baldini N,  Teti A, Marchisio PC, Zallone AZ: Adhesion properties and integrin expression of cultured human osteoclast-like cells. 212(2):209-18. Exp Cell Res. 1994

- Grano M, Faccio R, Colucci S, Paniccia R, Baldini N, Zallone AZ, Teti A: Extracellular Ca2+ sensing is modulated by pH in human osteoclast-like cells in vitro. 267(4 Pt 1):C961-8. Am J Physiol. 1994

- Grano M, Zigrino P, Colucci S, Zambonin G, Trusolino L, Serra M, Baldini N, Teti A, Marchisio PC, Zallone AZ: Adhesion properties and integrin expression of cultured human osteoclast-like cells. 212(2):209-18. Exp Cell Res. 1994

- Serra M, Scotlandi K, Manara MC, Maurici D, Lollini PL, De Giovanni C, Toffoli G, Baldini N: Establishment and characterization of multidrug-resistant human osteosarcoma cell lines. 13(2):323-9. Anticancer Res. 1993

- Picci P, Rougraff BT, Bacci G, Neff JR, Sangiorgi L, Cazzola A, Baldini N, Ferrari S, Mercuri M, Ruggieri P, et al: Prognostic significance of histopathologic response to chemotherapy in nonmetastatic Ewing's sarcoma of the extremities. 11(9):1763-9. 1993

- Rehan N, Bieling P, Winkler P, Helmke K, Maas R, Baldini N, Heise U, Fuchs N, Winkler K: The prognostic significance of tumor volume in osteosarcoma with neoadjuvant chemotherapy. 205(4):200-9 Klin Padiatr. 1993

- Scotlandi K, Serra M, Landuzzi L, Baldini N: SARG: a new human osteosarcoma cell line. Expression of bone markers and of major histocompatibility antigens. 3 Suppl 2:S29-31. Ann Oncol. 1992

- Scotlandi K, Baldini N, Campanacci M, Lollini PL, Picci P, Serra M: Induction of HLA class II antigens in osteosarcoma cells by interferons and tumor necrosis factor alpha. 12(3):767-72. Anticancer Res. 1992

- Serra M, Morini MC, Scotlandi K, Fisher LW, Zini N, Colombo MP, Campanacci M, Maraldi NM, Olivari S, Baldini N: Evaluation of osteonectin as a diagnostic marker of osteogenic bone tumors. 23(12):1326-31. Hum Pathol. 1992

- Baldini N, Scotlandi K, Serra M, Kusuzaki K, Shikita T, Manara MC, Maurici D, Campanacci M: Adriamycin binding assay: a valuable chemosensitivity test in human osteosarcoma. 119(2):121-6. J Cancer Res Clin Oncol. 1992

- Baldini N, Toni A, Greggi T, Giunti A: Deep sepsis from Mycobacterium tuberculosis after total hip replacement. Case report. 107(3):186-8. Arch Orthop Trauma Surg. 1988

- Bertoni F, Present D, Sudanese A, Baldini N, Bacchini P, Campanacci M: Giant-cell tumor of bone with pulmonary metastases. Six case reports and a review of the literature. (237):275-85. Review. Clin Orthop Relat Res.1988

- Boriani S, Picci P, Sudanese A, Toni A, Mancini A, Frezza G, Barbieri E, Baldini N, Monesi M, Ciaroni D, et al: Radio-induced sarcomas in survivors of Ewing's sarcoma. 74(5):543-51. Tumori. 1988

- Marchetti PG, Toni A, Baldini N, Binazzi R, D'Elia L, Sudanese A, Spinelli M: Clinical evaluation of 104 hip resection arthroplasties after removal of a total  hip prosthesis. 2(1):37-41. J Arthroplasty. 1987

- Campanacci M, Baldini N, Boriani S, Sudanese A: Giant-cell tumor of bone. 69(1):106-14. J Bone Joint Surg Am. 1987

- Dal Monte A, Donzelli O, Sudanese A, Baldini N: Congenital pseudarthrosis of the fibula. 7(1):14-8.J Pediatr Orthop. 1987

- Bertoni F, Calderoni P, Bacchini P, Sudanese A, Baldini N, Present D, Campanacci M: Benign fibrous histiocytoma of bone.68(8):1225-30.J Bone Joint Surg Am. 1986

- Picci P, Baldini N, Sudanese A, Boriani S, Campanacci M: Giant cell reparative granuloma and other giant cell lesions of the bones of the  hands and feet. 15(6):415-21.Skeletal Radiol. 1986

- Sudanese A, Toni A, Baldini N: Osteosarcoma as a primary second tumor in a patient with nonhereditary retinoblastoma. 72(5):535-7. Tumori. 1986

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