Argomenti di tesi proposti dal docente.
In our laboratory, we have two slots open for students with Biotechnology, Molecular Biology or Biology background. Below the topics, we will address during the one-year master thesis.
- From cancer vulnerability to cetuximab resistance: the role of IL-1 induced senescence
- Engineered cell system for MET receptor KO by CRISPR/CAS9 technology
Further details on our website: https://lauriolalab.com/
Ultime tesi seguite dal docente
Tesi di Laurea Magistrale
- CELTiC project: a clinical trial to confirm the predictive value of a panel of 4 mRNAs for colorectal cancer screening and response to cetuximab target therapy
- establishment of patients’-derived organoids from head and neck tumors
- Evaluation of MET in the regulation of perinuclear actin cap remodeling and its interplay with YAP1
- NF-κB oscillation profiles translate into resistance to anti-EGFR
monoclonal antibodies
- Targeting paracrine Neuregulin 1 to neutralize compensatory pathways to EGFR in Non Small Cell Lung Cancer
- Unveiling the role of microRNAs in the antagonistic interaction between EGFR and the Glucocorticoid Receptor
Tesi di Dottorato
- Aberrant c-MET activation impairs perinuclear actin cap organization with YAP1 cytosolic relocation