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Matteo Calvaresi

Professore associato

Dipartimento di Chimica "Giacomo Ciamician"

Settore scientifico disciplinare: CHIM/06 CHIMICA ORGANICA

Coordinatore del Corso di Dottorato in Nanoscienze per la medicina e per l'ambiente

Curriculum vitae

PERSONAL INFORMATION
Calvaresi, Matteo (March, 14th 1979, San benedetto del Tronto, AP)
Researcher identifier: 0000-0002-9583-2146
URL for web site: https://site.unibo.it/nanobio-interface-lab/en


EDUCATION
2008 PhD in Chemistry, Department of Chemistry G. Ciamician, Alma Mater Studiorum - Università di Bologna, Bologna
2004 Laurea in Chemistry, 110/110 summa cum Laude, Department of Chemistry G. Ciamician, Alma Mater Studiorum - Università di Bologna, Bologna

CURRENT & PREVIOUS POSITIONS
2021 - Present Member of the Alma Mater Institute on Healthy Planet, Alma Mater Studiorum Università di Bologna
2021 - Present Member of the Centre for Applied Biomedical Research – CRBA, Alma Mater Studiorum Università di Bologna
2020 - Present Member of the Interdepartmental Center for Industrial Research (CIRI)- Life sciences and health Technologies (Responsible for the areas: Biomaterial Functionalization and Therapeutic Proteins)
2018 - Present Associate Professor, Alma Mater Studiorum Università di Bologna
2018 - Present Associated Editor "Molecules" - Section Nanochemistry, MDPI
2017 - Present. Deputy Coordinator of the PhD Program "Nanoscience for Medicine and the Environment", Alma Mater Studiorum Università di Bologna
2011 - 2018 Assistant Professor, Alma Mater Studiorum Università di Bologna
2016 Visiting Scientist, Technion – Israel Institute of Technology, Israel
2013 Visiting Professor, University of Pune, India
2008 - 2011 Postdoctoral Fellow, Alma Mater Studiorum Università di Bologna
2009 Visiting Scientist, College of Chemistry and Molecular Engineering, Peking University, China

SECURED GRANTS
2022-2024 ECLIPSE, ECL-based Infectious Pathogen (bio)Sensor, EIC Pathfinder Open, funded by EU, (€143.765)
2022-2024 LIGHTNING - Light-enhanced cytotoxicity of anticancer agents by photoactivation, AIRC Fellowship (€75.000) NanoBio Interface Lab: hosting group
2022 TemoTaxi - Carrying temoporfin with proteins: towards the development of a phototheranostic platform for head and neck cancers, Fellowship Fondazione Umberto Veronesi (€30.000), NanoBio Interface Lab: hosting group
2021 – 2024 NEUROSHUTTLE, Wireless And Non-Genetic Photostimulation Of Neurons By Cell-Specific Targeting Of Photovoltaic Nanoparticles: Application To Neurodegenerative Diseases Of Retina And Brain. Funded by MIUR (Italian Ministry of Education, Universities and Research), (€172.600) - co-PI
2021- 2023 - NeuroPhage: Phage-based targeted neural stimulation in neurodegenerative diseases; JPND (Joint Programming Neurodegenerative Disease), PI
2021-2023 BOBCAT: Biocompatible Boron Carriers for Boron Neutron Capture Therapy, AIRC Fellowship (€75.000) NanoBio Interface Lab: hosting group
2021 ITACA: Improving Photosensitizer Performances by Protein Carriers, AIRC Fellowship (€25.000) NanoBio Interface Lab: hosting group
2021 - Modular phage vector platform for sonodynamic therapy, Proof-of-Concept competitive Grant (Ministry of Economic Development -MISE/UniBO), (€25.000), co-PI
2019 - 2024 NanoPhage: An Innovative Hybrid Platform for Targeted Sono- Photo- Dynamic Cancer Therapy, AIRC Grant (MFGA) (€498.000) - PI
2019-2021 SYNERGY. Fullerene@protein hybrids: multifunctional photo/sono sensitizers for anticancer therapy, AIRC Fellowship (€75.000) NanoBio Interface Lab: hosting group
2018-2020 Graphene Core 2, funded by Graphene Flagship, (€160.000), co-PI
2016-2018 BIOTAXI - Hybrid fullerene/protein-carriers to target cancer cells, SIR “The Scientific Independence of young Researchers programme”; Funded by MIUR (Italian Ministry of Education, Universities and Research) (€338.000) - PI
2016-2018 Graphene Core 1, funded by Graphene Flagship, (€160.000), co-PI
2014-2016 Ramp-up phase FP7, CemPHENE project, funded by Graphene Flagship, (€123.900), co-PI
2014-2015 CaFuMa – Calcium carbonate/graphene functional hybrid materials, Joint Project Italian Ministry of Foreign Affairs (Directorate General for Political and Security Affairs) and Israeli Ministry of Science and Technology, (€123.900), co-PI

BIBLIOMETRIC INDEXES
GOOGLE SCHOLAR: h-index = 28; publications = 129; citations 2699
MC published in the major international peer-reviewed multi-disciplinary scientific journals and in the leading chemical and nanotechnological journals as Nature Nanotechnology, PNAS, Acc. Chem. Res., JACS, Angew. Chem., ACS Nano, Material Horizons, Adv. Functional/Healthcare Materials, Biomaterials, Small, Nanoscale et al.


GRANTED PATENTS
1) Calvaresi, M.; Cantelli, A; Danielli, A.; Di Giosia, M.; Nigro, M.; Sart, E.; Starinieri, F. Modular phage vector platform for sonodynamic therapy. IT 102019000010131
2) Pokroy, B.; Calvaresi, M.; Falini, G. Crystals as hosts for entrapment and slow release of compounds. WO2016IL50533
3) Bonacchi, S.; Montalti, M.; Prodi, L.;;Zaccheroni, N.; Zerbetto, F.; Calvaresi, M.; Cauzzi, D. A. Use of a coordination complex or compound for the measurement of temperature. WO 2012056415.

FELLOWSHIPS AND AWARDS
2021 Invited to the Quirinale Palace by the President of the Italian Republic, Sergio Mattarella for the “Cancer Research Days”
2019 My First AIRC Grant (MFAG) – Transition to independence" - Italian Association for Cancer Research
2018 Habilitation Full Professor in Organic Chemistry, Italian National Agency For The Evaluation of Universities and Research Institutes
2015 Scientific Independence of young Researchers - BIOTAXI Ministry of Education, University and Research
2012 Winner of the UNIBO International Mobility Funds, Alma Mater Studiorum - Università di Bologna, Bologna
2009 Winner of a “Marco Polo” Fellowship, Alma Mater Studiorum - Università di Bologna, Bologna
2005 Winner of a competitive project within the framework of European Social Fund. SPINNER project of industrial cooperation with a Technology transfer project: in collaboration with Nerviano Medical Science Srl and CINECA. Regione Emilia Romagna

TEACHING ACTIVITIES
2020 – to date “Reaction Mechanisms”, Chemistry degree course at Alma Mater Studiorum Università di Bologna, Bologna
2012 – to date “Laboratory for Organic Chemistry” Chemistry degree course at Alma Mater Studiorum - Università di Bologna, Bologna
2013 – to date “Design of Functional Molecules” Chemistry degree course at Alma Mater Studiorum - Università di Bologna, Bologna

STUDENT/POSTDOC MENTOR
Master student (Experimental thesis): more than 50 from 2012; Post docs: 10; PhD tutoring: 7;

EDITORIAL/REVIEWING ROLES
2022 Guest Editor “Cancers”, Special Issue "Cancer Nanotherapy and Nanodiagnostic”
2018 – to date Associated Editor "Molecules" - Section Nanochemistry MDPI
Reviewer for some the major international peer-reviewed multi-disciplinary scientific journals and for the leading chemical and nanotechnological journals
Nature Publishing Group – NPG (i.e Nature Nanotechnology, Nature Communications)
American Chemical Society - ACS ( i.e. Journal of American Chemical Society, ACS Nano, Nano Letters, ACS Applied Materials & Interfaces )
Royal Chemical Society - RCS (i.e. Chemical Society Reviews, Chemical Communications, Journal of Materials Chemistry A/B/C,)
Wiley (i.e Advanced materials, Advanced Healthcare Materials, Chemistry – A European Journal)
Elsevier (i.e. NanoToday, Nanomedicine)

COMMISSIONS OF TRUST
In Italy: Evaluation of Basic Research Investment Fund (FIRB) projects, Evaluation of Italian Projects of National Interest (PRIN), Evaluation of Research Projects at the University of Turin, University of Florence and UNIMORE.
Evaluation of Research Quality at the National Agency for the Evaluation of Universities and Research Institutes, Italy
Outside Italy: Evaluation of Research Projects at ETH Zurich Research Commission (Swiss), at the Czech Science Foundation (Czech Republic), at the National Science Center (Poland) , at the Fondo Nacional de Desarrollo Científico y Tecnológico, (FONDECYT) (Chile), at the Foundation for Polish Science (Poland)
Evaluation for Norman Heatley Award, RSC Chemistry Biology Interface Division Awards Committee, UK

INVITED TALKS TO INTERNATIONAL CONGRESSES/ADVANCED SCHOOLS
The PI is an internationally recognized scientist in the field of nanomedicine: he was invited speaker in many important international conferences and international advanced schools.
Ten Selected Confererences/Schools
1) BIOTAXI - Proteins as ‘Trojan Horses’ for theranostic applications". CMB-B2F2 Joint Seminar Series, 16 June 2021, Bologna
2) “BIOTAXI: Biomolecular carriers for theranostic applications”, invited by IIT, Genova, 3 February 2020
3) “Proteins as supramolecular hosts for nano-objects” SUPRAMOL, 13th Italian Conference on Supramolecular Chemistry, Santa Margherita di Pula (CA), 18th-21st June 2017
4) “BIO-SUPRAMOLECULES: Design, Preparation and Characterization of Protein - Carbon Nanoparticle Hybrids, invited keynote Lecture , E-MRS 2018 Fall Meeting, University of Technology in Warsaw (Poland), 19 September, 2018.
5) “Hole in One: the First Foolproof Evidence of a 1:1 Carbon-Nanoparticle/Protein Adduct” €-MRS, Simposium P : Carbon materials: surface chemistry and biomedical applications, Lille, France, May 26, 2014
6) “The devil and holy water: designing protein / carbon nanotube hybrid systems” ChemOnTubes, March 30th- April 3rd 2014, Riva del Garda, Italy
7) “Nanobiotechnology : when Proteins Encounter Carbon Nanoparticles...” National Chemical laboratory (NCL), Pune, India, January 25, 2013
8) “Reverse-Docking Approach to Virtual Screening : a Powerful Tool for Computationally Driven Drug Discovery and Nanotechnology.” University of Pune, India, January 23, 2013,
9) “Baiting proteins with fullerenes” €-MRS, Simposium B: Bio-inspired and bio-integrated materials as new frontiers nanomaterials, Nice, France, May 10, 2011
10) “Computational Nanotechnology” Seminar@College of Chemistry and Molecular Engineering, Peking University, China, March 5, 2009

DISSEMINATION ACTIVITIES
The research activities of Matteo Calvaresi were also disseminated in the main Italian newspapers (i.e. la Repubblica, Il Resto del Carlino), radio (Radio 24), televisions (TG3), science blogs (i.e. Le Scienze) and international news services (EurekaAlert!).
Matteo Calvaresi organized outdoor laboratories at the European “Researcher’s Night”, and he was invited to communicate his research at schools and public events.

 

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