Foto del docente

Marina Martello

Professoressa a contratto

Dipartimento di Scienze per la Qualità della Vita

Curriculum vitae

Scarica Curriculum Vitae (.pdf 420KB )

Clinical Molecular Biologist | Translational Researcher in Hematologic Malignancies | Multiple Myeloma & Precision Medicine

PROFESSIONAL PROFILE

Translational scientist with 10+ years of experience in hematologic malignancies, with a primary focus on Multiple Myeloma genomic evolution, minimal residual disease (MRD), and precision medicine approaches.

Expert in liquid biopsy, next-generation sequencing, single-cell technologies, immunophenotyping and AI-driven genomic analysis, actively involved in international consortia and European projects integrating genomics and artificial intelligence in hematology.

Award-winning investigator, associate editor, and member of major international scientific societies (EHA, AACR, EACR).

CURRENT POSITION

Post-Doctoral Fellow
Institute of Hematology and Oncologic Sciences “L. & A. Seràgnoli”
University of Bologna – IRCCS S. Orsola, Bologna
Laboratory of Molecular Biology – Prof. Elena Zamagni

  • Translational research in lymphoproliferative disorders, with emphasis on Multiple Myeloma
  • Genomic and immunophenotypic characterization of disease
  • Development and application of MRD monitoring strategies
  • Implementation of liquid biopsy platforms
  • Integration of artificial intelligence tools for molecular stratification and disease monitoring
  • Active participation in European clinical trials and multicenter research initiatives

PREVIOUS ACADEMIC POSITIONS

2023–2025 – Fixed-term Researcher (SSD MEDS-09/B)

DIMEC – University of Bologna

2019 – Post-Doctoral Fellow – AIRC IG-2019

Project: “StreaMMing: dynamics of Multiple Myeloma minimal residual disease in peripheral blood”

2017–2018 – Post-Doctoral Fellow

Project: Plasma cell differentiation and Hedgehog pathway in Multiple Myeloma

2015–2016 – Post-Doctoral Fellow

Project: High-resolution molecular characterization of Acute Myeloid Leukemia toward precision medicine

2014 – Post-Doctoral Fellow

Project: Clonal evolution in Multiple Myeloma and genomic ecosystem characterization

EDUCATION

2017-2018: International II level Master on Nutrition and Diet at Università delle Marche

Thesis title: “Influence of diet on the composition of gut microbiota and its implications in cancer”.

Tutor: Prof. Battino M.

2016: Visiting fellow at Dana Farber Cancer Center (Boston, MA)

Selected scientist at the “Translational Workshop for Basic Scientists” organized by AACR, and

visiting fellow at Dana Farber Cancer Center and Massachussets General Hospital in Boston

2011-2013: PhD in Biomedical Sciences at University of Bologna

Thesis title: “The search for Multiple Myeloma Stem Cells: molecular characterization and self

renewal mechanisms involved in the disease persistence”. Tutor: Prof. Martinelli G.

2008-2010: Master degree cum laude in Pharmaceutical Biotechnology at University

of Bologna

Thesis title: “Molecular characterization of CD138+ tumoral plasma cells of newly diagnosed

patients with Multiple Myeloma by SNP array”. Tutor: Prof. Capranico G

2003-2008: Bachelor degree in Molecular Biotechnology at University of Bologna

Thesis title: “Development of a DNA microarray for the characterization of human gut microbiota”.

Tutor: Prof. Brigidi P.

COMPETITIVE FUNDED PROJECTS

PRIN 2022RandoMMness: Spatial heterogeneity of Multiple Myeloma unveiled by liquid biopsy

EU Project – GENOMED4ALL: AI-driven genomics for personalized medicine in hematological diseases

EU Grant n. 101172872: Synthetic data framework for AI validation in healthcare

AIRC-IG2018 – MRD dynamics in Multiple Myeloma

AIRC-IG2014 – Treatment strategies and intra-clonal heterogeneity in MM

BERLUCCHI 2014 – Development of MM molecular panel for patient stratification

HONOURS and AWARDS

Registered to the FNOB – Federazione Nazionale Ordine Biologi (n. AA084102) since 2020

Member of EHA2026 Scientific Program Committee Advisory Board (SPC-AB)

Participation to international and national congresses as a speaker

Author, co-author and reviewer for international scientific journals

Comment on a scientific paper for FAD Blood online.it (January 2024)

Associate editor for Molecular Diagnostics and Therapeutics - specialty section of Frontiers in Molecular Biosciences since 2024

Guest editor of PLOS ONE Editorial Board since 2023

2021 IMS Young Investigator Award for Exemplary Abstract, IMW 2021, Wien

2019 ASH abstract achievement award, 61stASH Annual Meeting, Orlando

2019 EHA Travel grant - 24thEuropean Hematology Congress, Amsterdam

2019 Early Career Award - 2ndHow to Diagnose and Treat Myeloma, Berlin

2018 EHA Travel grant - 23thEuropean Hematology Congress, Stockholm

2015 Rising Star award at the 15thInternational Myeloma Workshop, Rome

2014 AACR-Pezcoller Foundation Scholar-in-Training Award at AACR Meeting, San Diego

PROFESSIONAL MEMBERSHIP

Member of European Society of Cancer Research (EACR) since 2020, Member of Italian Society of Hematology (SIE and SIES) since 2011, Member of European Hematology Association (EHA) since 2012, Associate Member of American Association of Cancer Research (AACR) since 2012

EXTRA-ACADEMIC EDUCATION

2025 Selected scientist at EHATiFPreceptorship on Precision Hematology in Homburg, Germany

2025 Last GCP R3 training: 03/09/2025

2018 Training promoted by Cytognos “Analysis of MM MRD samples using the EuroFlow NGF methodology” - Policlinico S. Orsola – Malpighi, Bologna

2016 Training course “R for basic users”, Università Studi Milano - Bicocca

2014 Training course “Flow citometry: methods and applications”, Policlinico S. Orsola – Malpighi, Bologna

2014 Training course “Introduction to the System Biology” – Corso Alta Formazione, Università dell’Insubria, Prof M. Fasano

2010 Art&Science Workshop – in collaboration with Fondazione Marino Golinelli and MaMbo – Galleria d’Arte Moderna, Bologna

TECHNICAL EXPERTISE

Genomics & Molecular Biology

  • Next-Generation Sequencing (Illumina, Ion Torrent, Oxford Nanopore)
  • Whole Genome & Whole Exome Sequencing
  • Targeted gene panels
  • Single-cell sequencing
  • Immunosequencing (Adaptive ClonoSEQ)
  • SNP array & gene expression microarrays
  • Digital PCR & quantitative RT-PCR

Disease Monitoring

  • Minimal Residual Disease (NGS-based & EuroFlow NGF)
  • Liquid biopsy platforms

Computational & Analytical

  • Bioinformatic analysis of genomic data
  • AI integration in genomics
  • R (basic level)

TEACHING & EDUCATIONAL ACTIVITIES

National Scientific Habilitation on 05/E3 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA until 14/03/2037

Faculty Member – Master in “Management del paziente con Mieloma Multiplo” (University of Turin, since 2019)

Faculty in educational programs sponsored by Takeda, BMS, Sanofi, Janssen, GSK

A.A.: 2018/2019: Teaching on a behalf of Prof. Zamagni E. during the course “Genetica Onco ematologica e delle emopatie” SSD: MED15

A.A.2024/2025, A.A. 2025/2026: FISIOLOGIA UMANA C. I. [cod. 31360] - FISIOLOGIA DEGLI ORGANI E DEGLI APPARATI [cod. 30766] - [Modulo 2]

 

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