Baglioni M.; Fiume L.; Bolondi L.; Farina C.; Kratz F.; Di Stefano G., Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties., «DIGESTIVE AND LIVER DISEASE», 2008, 40, pp. 963 - 964 [articolo]
Di Stefano G.; Fiume L.; Baglioni M.; Busi C.; Bolondi L.; Farina C.; Mori F.; Chieco P.; Pariali M.; Kratz F.; Molin L.; Salmaso S.; Caliceti P., Doxorubicin coupled to lactosaminated albumin: effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats., «EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES», 2008, 33, pp. 191 - 198 [articolo]
Di Stefano G.; Fiume L.; Baglioni M.; Bolondi L.; Chieco P.; Kratz F.; Pariali M.; Rubini G., Efficacy of doxorubicin coupled to lactosaminated albumin on rat hepatocellular carcinomas evaluated by ultrasound imaging., «DIGESTIVE AND LIVER DISEASE», 2008, 40, pp. 278 - 284 [articolo]
Di Stefano G; Fiume L; Baglioni M; Busi C; Chieco P; Kratz F; Mattioli A., Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin, «EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES», 2007, 30, pp. 136 - 142 [articolo]
Di Stefano G.; Fiume L.; Baglioni M.; Bolondi L.; Busi C.; Chieco P.; Kratz F.; Manaresi F.; Pariali M., A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentation grade., «LIVER INTERNATIONAL», 2006, 26, pp. 726 - 733 [articolo]
Di Stefano G; Fiume L; Domenicali M; Busi C; Chieco P; Kratz F; Lanza M; Mattioli A; Pariali M; Bernardi M., Doxorubicin coupled to lactosaminated albumin: effects on rats with liver fibrosis and cirrhosis., «DIGESTIVE AND LIVER DISEASE», 2006, 38, pp. 404 - 408 [articolo]
Di Stefano G.; Busi C.; Chieco P.; Pariali M.; Fiume L., Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas., «DIGESTIVE AND LIVER DISEASE», 2006, 38, pp. 284 - 285 [articolo]
Brevetto n. PCT/EP2006/066489, Use of conjugates of doxorubicin with lactosaminated albumin..
FIUME L.; BOLONDI L.; BUSI C.; CHIECO P.; KRATZ F.; LANZA M.; MATTIOLI A.; DI STEFANO G., Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine., «JOURNAL OF HEPATOLOGY», 2005, 43, pp. 645 - 652 [articolo]
DI STEFANO G.; FIUME L.; BOLONDI L.; LANZA M.; PARIALI M.; CHIECO P., Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors., «LIVER INTERNATIONAL», 2005, 25, pp. 854 - 860 [articolo]
Brevetto n. PCT/IT2005/000257, Process for the preparation of doxorubicin conjugates with lactosaminated human albumin.
Brevetto n. MI2005A001743, Uso di coniugati della doxorubicina con albumina lattosaminata.
DI STEFANO G.; LANZA M.; KRATZ F.; MERINA L.; FIUME L., A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate., «EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES», 2004, 23, pp. 393 - 397 [articolo]
DI STEFANO G.; DERENZINI M.; KRATZ F.; LANZA M.; FIUME L., Liver targeted doxorubicin: effects on rat regenerating hepatocytes., «LIVER INTERNATIONAL», 2004, 24, pp. 246 - 252 [articolo]
Brevetto n. MI2004A000928, Procedura per la preparazione di coniugati della doxorubicina con l’albumina umana lattosaminata.
