Foto del docente

Giovanna Farruggia

Assistant professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/10 Biochemistry

Publications

Emil Malucelli; Stefano Iotti; Alessandra Gianoncelli; Michela Fratini; Lucia Merolle; Andrea Notargiacomo; Chiara Marraccini; Azzurra Sargenti; Concettina Cappadone; Giovanna Farruggia; Inna Bukreeva; Marco Lombardo; Claudio Trombini; Jeanette A. Maier; Stefano Lagomarsino, Quantitative Chemical Imaging of the Intracellular Spatial Distribution of Fundamental Elements and Light Metals in Single Cells, «ANALYTICAL CHEMISTRY», 2014, 86, pp. 5108 - 5115 [Scientific article]

Alberto Leoni; Alessandra Locatelli; Rita Morigi; Mirella Rambaldi; Concettina Cappadone; Giovanna Farruggia; Stefano Iotti; Lucia Merolle; Maddalena Zini; Claudio Stefanelli, Substituted E-3-(3-indolylmethylene)1,3-dihydroindol-2-ones with antiproliferative activity. Study of the effects on HL-60 leukemia cells, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2014, 79, pp. 382 - 390 [Scientific article]

Massimo Sgarzi;Marco Lombardo;Claudio Trombini;Nelsi Zaccheroni;Giovanna Farruggia;Lucia Merolle;Azzurra Sargenti;Stefano Iotti;Chiara Marraccini;Luca Prodi, Expanding the targets of the diaza-18-crown-6 hydroxyquinoline derivatives family to Zn(II) ions for intracellular sensing, «SUPRAMOLECULAR CHEMISTRY», 2013, 25, pp. 7 - 15 [Scientific article]

A. Minarini; M. Zini; A. Milelli; V. Tumiatti; C. Marchetti; B. Nicolini; M. Falconi; G. Farruggia; C. Cappadone; C. Stefanelli, Synthetic polyamines activating autophagy: Effects on cancer cell death, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2013, 67, pp. 359 - 366 [Scientific article]

Malucelli, E; Iotti, S; Fratini, M; Marraccini, C; Notargiacomo, A; Gianoncelli, A; Bukreeva, I; Cedola, A; Maier; J; Farruggia, G; Cappadone, C; Merolle, L; Wolf; F; Trapani, V; Lagomarsino, S, X-ray fluorescence microscopy of light elements in cells: Self-absorption correction by integration of compositional and morphological measurements, «JOURNAL OF PHYSICS. CONFERENCE SERIES», 2013, 463, Article number: 012022 , pp. 1 - 4 [Scientific article]

A. Locatelli; R. Morigi; A. Leoni; M. Granaiola; L. Varoli; M. Rambaldi; A. Andreani; L. Merolle; C. Cappadone; G. Farruggia, Benzoindol-2-one derivatives inducing mitochondria-mediated apoptosis associated with magnesium content decrease, in: 21ST NATIONAL MEETING ON MEDICINAL CHEMISTRYBOOK OF ABSTRACTS, PALERMO, SCI, 2012, pp. 97 - 97 (atti di: 21ST NATIONAL MEETING ON MEDICINAL CHEMISTRY, Palermo, July 17 – 20, 2012) [Abstract]

C. Marraccini; G. Farruggia; M. Lombardo; L. Prodi; M. Sgarzi; V. Trapani; C. Trombini; F. I. Wolf; N. Zaccheroni; S. Iotti, Diaza-18-crown-6 hydroxyquinoline Derivatives as Flexible Tools for the Assessment and Imaging of Total Intracellular Magnesium, «CHEMICAL SCIENCE», 2012, 3, pp. 727 - 734 [Scientific article]

Cappadone C.; Merolle L.; Marraccini C.; Farruggia G.; Sargenti L.; Locatelli A.; Morigi R.; Iotti S., Intracellular magnesium content decreases during mitochondria-mediated apoptosis induced by a new indole-derivative in human colon cancer cells, «MAGNESIUM RESEARCH», 2012, 25, pp. 104 - 111 [Scientific article]

A. Andreani; M. Granaiola; A. Locatelli; R. Morigi; M. Rambaldi; L. Varoli; N. Calonghi; C. Cappadone; G. Farruggia; C. Stefanelli; L. Masotti; T.L. Nguyen; E. Hamel; R.H. Shoemaker, Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, citotoxic activity, and study of the mechanism of action., «JOURNAL OF MEDICINAL CHEMISTRY», 2012, 55, pp. 2078 - 2088 [Scientific article]

R. Morigi; A. Andreani; M. Granaiola; A. Locatelli; M. Rambaldi; L. Varoli; N. Calonghi; C. Cappadone; G. Farruggia; C. Stefanelli; L. Masotti; T. L. Nguyen; E. Hamel; R. H. Shoemaker, SYNTHESIS OF 3-(5-IMIDAZO[2,1-b]THIAZOLYLMETHYLENE)-2-INDOLINONES INHIBITING TUBULIN ASSEMBLY AND INDUCING APOPTOSIS IN HT-29 COLON CANCER CELLS, in: Nuove Prospettive in Chimica Farmaceutica, BOLOGNA, SCI, 2012, pp. 88 - 88 (atti di: 6° Meeting Nuove prospettive in Chimica Farmaceutica, Riccione (RN), 15-17 Aprile 2012) [Abstract]

Cappadone C.; Farruggia G.; Marraccini C.; Sgarzi M.; Lombardo M.; Iotti S., A new imidazothiazolylmethylen-oxindole induces apoptosis and decline in intracellular free and total magnesium in HT29 colon cancer cells, in: European Magnesium Meeting - EUROMAG Bologna 2011. Guest Editors: F.I. Wolf and S. Iotti, John Libbey Eurotext Ltd, «MAGNESIUM RESEARCH», 2011, 24 (3), pp. 136 - 136 (atti di: Magnesium Research Contents Volume 24, Number 3, September 2011 Magnesium Research Current issue Archives Subscribe Order an issue More information Advice to authors Online submission Visit the dedicated website: www.magnesiumresearch.com BIOLOGY OF MAGNESIUM AND ITS TRANSPORTERS: Implications In Human Diseases European Magnesium Meeting - EUROMAG Organized by the University of Bologna and by the International Society for the Development of Research on Magnesium, Bologna, Italy, 8-10 giugno 2011) [Abstract]

Marverti G; Ligabue A; Montanari M; Guerrieri D; Cusumano M; Di Pietro ML; Troiano L; Di Vono E; Iotti S; Farruggia G; Wolf F; Monti MG; Frassineti C., Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and-resistant human ovarian cancer cells., «INVESTIGATIONAL NEW DRUGS», 2011, 29, pp. 73 - 86 [Scientific article]

S. Lagomarsino; S. Iotti; G. Farruggia; A. Cedola; V. Trapani; M. Fratini; I. Bukreeva; A. Notargiacomo; L. Mastrototaro; C. Marraccini; A. Sorrentino; I. McNulty; S. Vogt; D. Legnini; S. Kim; A. Gianoncelli; J.M. Maier; F.I. Wolf, Intracellular concentration map of light elements in whole cells by complementary nano-probe methods, in: European Magnesium Meeting - EUROMAG Bologna 2011. Guest Editors: F.I. Wolf and S. Iotti, John Libbey Eurotext Ltd, «MAGNESIUM RESEARCH», 2011, 24(3), pp. 145 - 145 (atti di: II EUROMAG MEETING. BIOLOGY OF MAGNESIUM AND ITS TRANSPORTERS: Implications In Human Diseases, Bologna, 8-11 giugno 2011) [Abstract]

Lagomarsino S.; Iotti S.; Farruggia G.; Cedola A.; Trapani V.; Fratini M.; Bukreeva I.; Notargiacomo A.; Mastrototaro L.; Marraccini C.; Sorrentino A.; McNulty I.; Vogt S.; Legnini D.; Kim S.; Giagnoncelli A. Maier J.A.M; Wolf. F.I., Intracellular concentration map of magnesium in whole cells by combined use of X-ray fluorescence microscopy and atomic force microscopy., «SPECTROCHIMICA ACTA, PART B: ATOMIC SPECTROSCOPY», 2011, 66, pp. 834 - 840 [Scientific article]

C. Frassineti; D. Guerrieri; G. Marverti; F. Chiavolelli; S. De Lucia; G. Farruggia; S. Iotti, Magnesium concentration in cisplatin-sensitive and -resistant human ovarian cancer cell lines: preliminary results, in: European Magnesium Meeting - EUROMAG Bologna 2011. Guest Editors: F.I. Wolf and S. Iotti, John Libbey Eurotext Ltd, «MAGNESIUM RESEARCH», 2011, 24(3), pp. 143 - 143 (atti di: II EUROMAG MEETING. BIOLOGY OF MAGNESIUM AND ITS TRANSPORTERS: Implications In Human Diseases, Bologna, Italia, 8-11 giugno) [Abstract]