Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endothelial and Bone Marrow Mesenchymal Stromal Cells
Giuliani A, Bacalini MG, Ramini D, Mensà E, Giordani C; Xumerle L, Garagnani P, olivieri F, Procopio AD, Rippo MR, Sabbatinelli J. Cells 2023, 12, 285. doi:10.3390/cells12020285
Replicative Senescence-Associated LINE1 Methylation and LINE1-Alu Expression Levels in Human Endothelial Cells.
Ramini D, Latini S, Giuliani A, Matacchione G, Sabbatinelli J, Mensà E, Bacalini MG, Garagnani P, Rippo MR, Bronte G, Bonafè M, Cardelli M, Olivieri F. Cells. 2022 Nov 27;11(23):3799. doi: 10.3390/cells11233799.
Long-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs.
Giuliani A, Londin E, Ferracin M, Mensà E, Prattichizzo F, Ramini D, Marcheselli F, Recchioni R, Rippo MR, Bonafè M, Rigoutsos I, Olivieri F, Sabbatinelli J. Sci Rep. 2020 Dec 11;10(1):21782. doi: 10.1038/s41598-020-78871-5.
Pre-eclampsia predictive ability of maternal miR-125b: a clinical and experimental study.
Licini C, Avellini C, Picchiassi E, Mensà E, Fantone S, Ramini D, Tersigni C, Tossetta G, Castellucci C, Tarquini F, Coata G, Giardina I, Ciavattini A, Scambia G, Di Renzo GC, Di Simone N, Gesuita R, Giannubilo SR, Olivieri F, Marzioni D. Transl Res. 2021 Feb;228:13-27. doi: 10.1016/j.trsl.2020.07.011. Epub 2020 Jul 26.
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.
Mensà E, Guescini M, Giuliani A, Bacalini MG, Ramini D, Corleone G, Ferracin M, Fulgenzi G, Graciotti L, Prattichizzo F, Sorci L, Battistelli M, Monsurrò V, Bonfigli AR, Cardelli M, Recchioni R, Marcheselli F, Latini S, Maggio S, Fanelli M, Amatori S, Storci G, Ceriello A, Stocchi V, De Luca M, Magnani L, Rippo MR, Procopio AD, Sala C, Budimir I, Bassi C, Negrini M, Garagnani P, Franceschi C, Sabbatinelli J, Bonafè M, Olivieri F.J Extracell Vesicles. 2020 Feb 18;9(1):1725285. doi: 10.1080/20013078.2020.1725285. eCollection 2020.
Extracellular vesicles circulating in young organisms promote healthy longevity.
Prattichizzo F, Giuliani A, Sabbatinelli J, Mensà E, De Nigris V, La Sala L, de Candia P, Olivieri F, Ceriello A. J Extracell Vesicles. 2019 Aug 15;8(1):1656044. doi: 10.1080/20013078.2019.1656044. eCollection 2019.
NMR-Based Metabolomic Approach Tracks Potential Serum Biomarkers of Disease Progression in Patients with Type 2 Diabetes Mellitus.
Del Coco L, Vergara D, De Matteis S, Mensà E, Sabbatinelli J, Prattichizzo F, Bonfigli AR, Storci G, Bravaccini S, Pirini F, Ragusa A, Casadei-Gardini A, Bonafè M, Maffia M, Fanizzi FP, Olivieri F, Giudetti AM.J Clin Med. 2019 May 21;8(5). pii: E720. doi: 10.3390/jcm8050720.
Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging.
Scavello F, Zeni F, Tedesco CC, Mensà E, Veglia F, Procopio AD, Bonfigli AR, Olivieri F, Raucci A. Aging (Albany NY). 2019 Mar 23. doi: 10.18632/aging.101860.
Circulating miR-146a in healthy aging and type 2 diabetes: Age- and gender-specific trajectories.
Mensà E, Giuliani A, Matacchione G, Gurău F, Bonfigli AR, Romagnoli F, De Luca M, Sabbatinelli J, Olivieri F. Mech Ageing Dev. 2019 Mar 14;180:1-10. doi: 10.1016/j.mad.2019.03.001.
Postnatal development of the distribution of nitric oxide-producing neurons in the rat corpus callosum.
Barbaresi P, Mensà E, Sagrati A, Graciotti L.
Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians.
Storci G, De Carolis S, Papi A, Bacalini MG, Gensous N, Marasco E, Tesei A, Fabbri F, Arienti C, Zanoni M, Sarnelli A, Santi S, Olivieri F, Mensà E, Latini S, Ferracin M, Salvioli S, Garagnani P, Franceschi C, Bonafè M. Cell Death Differ. 2019 Jan 8. doi: 10.1038/s41418-018-0255-8.
The telomere world and aging: Analytical challenges and future perspectives.
Mensà E, Latini S, Ramini D, Storci G, Bonafè M, Olivieri F. Ageing Res Rev. 2019 Mar;50:27-42. doi: 10.1016/j.arr.2019.01.004. Epub 2019 Jan 4. Review.
The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells.
Giuliani A, Cirilli I, Prattichizzo F, Mensà E, Fulgenzi G, Sabbatinelli J, Graciotti L, Olivieri F, Procopio AD, Tiano L, Rippo MR. Aging (Albany NY). 2018 Oct 21;10(10):2855-2873. doi: 10.18632/aging.101591.
Pleiotropic effects of metformin: Shaping the microbiome to manage type 2 diabetes and postpone ageing.
Prattichizzo F, Giuliani A, Mensà E, Sabbatinelli J, De Nigris V, Rippo MR, La Sala L, Procopio AD, Olivieri F, Ceriello A. Ageing Res Rev. 2018 Dec;48:87-98. doi: 10.1016/j.arr.2018.10.003. Epub 2018 Oct 15. Review.
Physical Activity Modulates the Overexpression of the Inflammatory miR-146a-5p in Obese Patients.
Russo A, Bartolini D, Mensà E, Torquato P, Albertini MC, Olivieri F, Testa R, Rossi S, Piroddi M, Cruciani G, De Feo P, Galli F. IUBMB Life. 2018 Oct;70(10):1012-1022. doi: 10.1002/iub.1926. Epub 2018 Sep 13.
MiR-146a-5p correlates with clinical efficacy in psoriasis patients treated with the TNF alpha inhibitor Adalimumab.
Mensà E, Recchioni R, Marcheselli F, Giuliodori K, Consales V, Molinelli E, Prattichizzo F, Rippo MR, Campanati A, Procopio AD, Olivieri F, Offidani AM. Br J Dermatol. 2018 Apr 6. doi: 10.1111/bjd.16659.
Age-related modulation of plasmatic beta-Galactosidase activity in healthy subjects and in patients affected by T2DM.
Spazzafumo L*, Mensà E*, Matacchione G,* Galeazzi T, Zampini L, Recchioni R, Marcheselli F, Prattichizzo F, Testa R, Antonicelli R, Garagnani P, Boemi M, Bonafè M, Bonfigli AR, Procopio AD, Olivieri F. Oncotarget. 2017; 8:93338-93348. https://doi.org/10.18632/oncotarget.21848 .
Epigenetic effects of physical activity in elderly patients with cardiovascular disease.
Recchioni R, Marcheselli F, Antonicelli R, Mensà E, Lazzarini R, Procopio AD, Olivieri F. Exp Gerontol. 2017. doi: 10.1016/j.exger.2017.10.016.
Substance P NK1 receptor in the rat corpus callosum during postnatal development.
Barbaresi P, Mensà E, Bastioli G, Amoroso S. Brain and Behavior. 2017.
Bone marrow adipocytes support haematopoietic stem cell survival.
Mattiucci D, Maurizi G, Izzi V, Cenci L, Ciarlantini M, Mancini S, Mensà E, Pascarella R, Vivarelli M, Olivieri A, Leoni P, Poloni A. J Cell Physiol. 2017. doi: 10.1002/jcp.26037.
Exosome-based immunomodulation during aging: A nano-perspective on inflamm-aging. Prattichizzo F, Micolucci L, Cricca M, De Carolis S, Mensà E, Ceriello A, Procopio AD, Bonafè M, Olivieri F. Mech Ageing Dev. 2017.doi: 10.1016/j.mad.2017.02.008.
Leukocyte telomere length and mortality risk in patients with type 2 diabetes.
Bonfigli A.R, Spazzafumo L, Prattichizzo F, Bonafè M, Mensà E, Micolucci L, Giuliani A, Fabbietti P, Testa R, Boemi M, Lattanzio F, and Olivieri F. Oncotarget. 2016. 9;7(32):50835-50844. doi: 10.18632/oncotarget.10615.
Physical activity and progenitor cell-mediated endothelial repair in chronic heart failure: is there a role for epigenetics?
Recchioni R, Marcheselli F, Antonicelli R, Lazzarini R, Mensà E, Testa R, Procopio AD, Olivieri F. Mech Ageing Dev. 2016. pii: S0047-6374(16)30029-X. doi: 10.1016/j.mad.2016.03.008.
Connections from the rat dorsal column nuclei (DCN) to the periaqueductal gray matter (PAG).
Barbaresi P, Mensà E. Neuroscience Research. 2016. pii: S0168-0102(16)00045-6. doi:10.1016/j.neures.2016.02.003.
MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications.
Olivieri F, Spazzafumo L, Bonafè M, Recchioni R, Prattichizzo F, Marcheselli F, Micolucci L, Mensà E, Giuliani A, Santini G, Gobbi M, Lazzarini R, Boemi M, Testa R, Antonicelli R, Procopio A.D, Bonfigli A.R. Oncotarget. 2015 Nov 3; 6 (34): 35372-82.
Intracallosal nNOSneurons co-localize with NK1 substance P receptor in the rat.
Barbaresi P, Mensà E, Lariccia V, Desiato G, Fabri M, Gratteri S. J Comp Neurol. 2014 Oct 14. doi: 10.1002/cne.23695.
Characterization on NO-producing neurons in rat corpus callosum.
Barbaresi P, Fabri M, Mensà E. Brain and Behavior. 2014. May 4(3):317-36. doi: 10.1002/brb3.218.
HtrA1 in human urothelial bladder cancer: A secreted protein and a potential novel biomarker.
Lorenzi T, Lorenzi M, Altobelli E, Marzioni D, Mensà E, Quaranta A, Paolinelli F, Morroni M, Mazzucchelli R, De Luca A, Procopio AD, Baldi A, Muzzonigro G, Montironi R, Castellucci M. Int J Cancer. 2013 Dec 1;133(11):2650-61.
Differential distribution of parvalbumin- and calbindin-D28K-immunoreactive neurons in the rat periaqueductal gray matter and their colocalization with enzymes producing nitric oxide.
Barbaresi P, Mensà E, Lariccia V, Pugnaloni A, Amoroso S, Fabri M. Brain Res Bull. 2013 Oct 6. doi:pii: S0361-9230(13)00143-3.
Immunocytochemical localization of calretinin-containing neurons in the rat periaqueductal gray and colocalization with enzymes producing nitric oxide: a double, double-labeling study.
Barbaresi P, Quaranta A, Amoroso S, Mensà E, Fabri M. Synapse. 2012 Apr;66(4):291-307.
