Davide Carlo Ambrosetti

Tesi di Laurea Magistrale

• Analysis of the interaction of USP48 with ARL3 hypomorphic variants causative of autosomal recessive retinal dystrophy
• Development of RNA Therapies: Molecular Validation of Long Non-Coding RNAs as Therapeutic Targets in Non-Small Cell Lung Cancer
• Experimental advancements in COMRADES: an optimized strategy to study RNA structural dynamics
• Generation and characterization of DGCR8-mutated thyroid cell lines to model microprocessor-driven thyroid tumor formation.
• Involvement of ncRNAs in the modulation of cell metabolism during skeletal muscle ageing
• paired nuclear imaging and single cell atac-seq profiling of young and aged murine hematopoietic stem cells
• Uncovering lncRNA Driver Mutations in Lung Cancer through CRISPR Prime Editing