Foto del docente

Anna Maria Ghelli

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/10 Biochemistry

Publications

Calabrese C.; Iommarini L.; Kurelac I.; Calvaruso M.A.; Capristo M.; Lollini P.L.; Nanni P.; Bergamini C.; Nicoletti G.; De Giovanni C.; Ghelli A.; Giorgio V.; Caratozzolo M.F.; Marzano F.; Manzari C.; Betts C.M.; Carelli V.; Ceccarelli C.; Attimonelli M.; Romeo G.; Fato R.; Rugolo M.; Tullo A.; Gasparre G.; Porcelli A.M., Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells, «CANCER & METABOLISM», 2013, 1, Article number: 11 , pp. 1 - 15 [Scientific article]Open Access

Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; De Nardo V.; Martinuzzi A.; Wibrand F.; Vissing J.; Kurelac I.; Gasparre G.; Selamoglu N.; Daldal F.; Rugolo M., The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes, «HUMAN MOLECULAR GENETICS», 2013, 22, pp. 2141 - 2151 [Scientific article]

Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M., Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder, in: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS», 2012, 1817, pp. S139 - S139 (atti di: EBEC 2012 - 17th European Bioenergetics Conference, Freiburg, 15-20 September 2012) [Abstract]

Giorgio V; Petronilli V; Ghelli A; Carelli V; Rugolo M; Lenaz G; Bernardi P, The effects of idebenone on mitochondrial bioenergetics, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS», 2012, 1817, pp. 363 - 369 [Scientific article]

Carelli V.; Schimpf S.; Fuhrmann N.; Valentino M.L.; Zanna C.; Iommarini L.; Papke M.; Schaich S.; Tippmann S.; Baumann B.; Barboni P.; Longanesi L.; Rugolo M.; Ghelli A.; Alavi M.V.; Youle R.J.; Bucchi L.; Carroccia R.; Giannoccaro M.P.; Tonon C.; Lodi R.; Cenacchi G.; Montagna P.; Liguori R.; Wissinger B., A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16., «HUMAN MOLECULAR GENETICS», 2011, 20, pp. 1893 - 1905 [Scientific article]

Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM, A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function, «CANCER RESEARCH», 2011, 71, pp. 6220 - 6229 [Scientific article]

Gonzalez-Halphen D; Ghelli A; Iommarini L; Carelli V; Degli Esposti M, Mitochondrial complex I and cell death: a semi-automatic shogun model, «CELL DEATH & DISEASE», 2011, 2, Article number: e222 , pp. 1 - 7 [Scientific article]Open Access

Giordano C.; Montopoli M.; Perli E.; Orlandi M.; Fantin M.; Ross-Cisneros F.N.; Caparrotta L.; Martinuzzi A.; Ragazzi E.; Ghelli A.; Sadun A.A.; d'Amati G.; Carelli V., Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy., «BRAIN», 2011, 134, pp. 220 - 234 [Scientific article]

A.M.Porcelli ;A. Ghelli ;C. Ceccarelli ;M. Lang ;G. Cenacchi ; M.Capristo ;L.F. Pennisi ; I.Morra; E.Ciccarelli ; A.Melcarne ; A.;Bartoletti-Stella; N .Salfi ; G.Tallini ; A.Martinuzzi ; V.Carelli ; M.Attimonelli ; M.Rugolo ;G. Romeo ; G.Gasparre ., The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization, «HUMAN MOLECULAR GENETICS», 2010, 19 (issue 6), pp. 1019 - 1032 [Scientific article]

G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli., An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells., «HUMAN MUTATION», 2009, 30 (3), pp. 391 - 396 [Scientific article]

Iommarini L.; Martelli P.L.; Ghelli A.; Rugolo M.; Casadio R.; Carelli V., Modelling ND subunits of complex I: Leber’s Hereditary Optic Neuropathy (LHON) pathogenic mutations and non-synonymous population variants in genotype-phenotype correlation, in: Proceedings of Mitochondial Medicine 2009, s.l, s.n, 2009, pp. 194 - 195 (atti di: Mitochondial Medicine 2009, Vienna, Virginia, USA, 24-27 Giugno 2009) [Abstract]

A. M. Porcelli; A. Angelin; A. Ghelli; E. Mariani; A. Martinuzzi; V. Carelli; V. Petronilli; P. Bernardi; M. Rugolo, Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels, «THE JOURNAL OF BIOLOGICAL CHEMISTRY», 2009, 284, pp. 2045 - 2052 [Scientific article]

Ghelli A.; Porcelli A.M.; Zanna C.; Vidoni S.; Mattioli S.; Barbieri A.; Iommarini L.; Pala M.; Achilli A.; Torroni A.; Rugolo M.; Carelli V., The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity., «PLOS ONE», 2009, 4, Article number: e7922 , pp. 1 - 11 [Scientific article]Open Access

Zanna C.; Ghelli A.; Porcelli A.M.; Karbowski M.; Youle R.J.; Schimpf S.; Wissinger B.; Pinti M.; Cossarizza A.; Vidoni S.; Valentino M.L.; Rugolo M.; Carelli V., OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion., «BRAIN», 2008, 131, pp. 352 - 367 [Scientific article]

Ghelli A.; Porcelli A.M.; Zanna C.; Martinuzzi A.; Carelli V.; Rugolo M., Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids., «INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE», 2008, 49, pp. 671 - 676 [Scientific article]

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