Foto del docente

Santi Mario Spampinato

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/14 Pharmacology

Head of Department of Pharmacy and Biotechnology


L. Varoli; A. Andreani; S. Burnelli; M. Granaiola; A. Leoni; A. Locatelli; R. Morigi; M. Rambaldi; A. Bedini; N. Fazio; S. Spampinato, Diphenidol-related diamines as novel muscarinic M4 receptor antagonists, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2008, 18, pp. 2972 - 2976 [Scientific article]

R. Budriesi; P. Ioan; A. Locatelli; S. Cosconati; A. Leoni; M. P. Ugenti; A. Andreani; R. Di Toro; A. Bedini; S. Spampinato; L. Marinelli; E. Novellino; A. Chiarini., Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 1592 - 1600 [Scientific article]

L. Gentilucci; F. Squassabia; R. De Marco; R. Artali; G. Cardillo; A. Tolomelli; S. Spampinato; A. Bedini., Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR, «THE FEBS JOURNAL», 2008, 275, pp. 2315 - 2337 [Scientific article]

G. Bombieri; R. Artali; L. Gentilucci; R. De Marco; S. Spampinato; A. Bedini;, Investigation on MOR receptor activation by atypical mechanisms, in: XIX NMMC, Book of abstracts, s.l, s.n, 2008, pp. 12 - 12 (atti di: XIX NMMC, Verona, 14-18 sett. 2008) [Abstract]

Guarino G.; Spampinato S., Nandrolone decreases mu opioid receptor expression in SH-SY5Y human neuroblastoma cells, «NEUROREPORT», 2008, 19, pp. 1131 - 1135 [Scientific article]

Bucolo C.; Maltese A.; Maugeri F.; Ward K.W.; Baiula M.; Spartà A.; Spampinato S., New coumarin-based anti-inflammatory drug: putative antagonist of the integrins alpha(L)beta(2) and alpha(M)beta(2)., «JOURNAL OF PHARMACY AND PHARMACOLOGY», 2008, 60, pp. 1473 - 1479 [Scientific article]

L. Gentilucci; G. Cardillo; S. Spampinato; A. Tolomelli; F. Squassabia; R. De Marco; M. Baiula, Peptidomimetic Scaffolds for the Discovery of New Bioactive Compounds. Cyclotetrapeptide Analogues Based on a 13-Membered, Partially Modified Retro-Inverso Structure. Applications to the synthesis of Cancer Cell Adhesion Inhibitors, in: SISOC-7, Book of Abstracts, s.l, s.n, 2008, pp. IL-12 - IL-12 (atti di: SPANISH-ITALIAN SYMPOSIUM ORGANIC CHEMISTRY, Oviedo, 7-12 sett. 2008) [Abstract]

F. Fontana; P. Bernardi; C. Pizzi; U. Paradossi; S. Spampinato, Plasma Brain Natriuretic Peptide at rest and after adenosine-induced myocardial ischemia in normotensive and essential hypertensive patients with suspected coronary artery disease, in: , «GIORNALE ITALIANO DI CARDIOLOGIA», 2008, 9, pp. 247 - 247 (atti di: 69 Congresso Nazionale della Societa' Italiana di Cardiologia, Roma, Italia, 13-16 Dicembre 2008) [Abstract]

L. Varoli; P. Angeli; M. Buccioni; S. Burnelli; N. Fazio; G. Marucci; M. Recanatini; S. Spampinato, Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists, «MEDICINAL CHEMISTRY», 2008, 4, pp. 121 - 128 [Scientific article]

Bedini A.; Baiula M.; Spampinato S., Transcriptional activation of human mu-opioid receptor gene by insulin-like growth factor-I in neuronal cells is modulated by the transcription factor REST, «JOURNAL OF NEUROCHEMISTRY», 2008, 105, pp. 2166 - 2178 [Scientific article]

F. Fontana; P. Bernardi; C. Pizzi; R. Di Toro; S. Spampinato, β-Endorphin in pressor response to hyperventilation in elderly patients with essential and secondary hypertension, «CENTRAL EUROPEAN JOURNAL OF MEDICINE», 2008, 3, pp. 55 - 63 [Scientific article]

Spampinato S.; Baiula M.; Calienni M., Agonist-Regulated Internalization and desensitization of the Human Nociceptin Receptor Expressed in CHO Cells, «CURRENT DRUG TARGETS», 2007, 8, pp. 137 - 146 [Scientific article]

Gentilucci L.; Cardillo G. ; Squassabia F.; Tolomelli A.; Spampinato S.; Sparta A.; Baiula M., Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics., «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2007, 17, pp. 2329 - 2333 [Scientific article]

GABRIELE CAMPANA; WILLIAM RAFFAELI; DONATELLA SARTI; SANTI SPAMPINATO., Long-term intrathecal morphine in patients with cronic non-camcer pain up-regulates mu opioid receptor gene expression in lymphocytes., in: Atti: XXXIII Congresso Nazionale della Società Italiana di Farmacologia, MILANO, Societa' Italiana di Farmacologia, 2007(atti di: XXXIII Congresso Nazionale della Società Italiana di Farmacologia, Cagliari, 6-9 Giugno 2007) [Abstract]

Patent n. RM2007A000005, Oligonucleotidi antisenso anti pro-opiomelanocortina ipofisiaria e loro uso in campo medico per la prevenzione e la terapia della sindrome post-traumatica da stress (PTSD).