Bruno S.; Mancini M.; De Santis S.; Monaldi C.; Cavo M.; Soverini S., The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2021, 22, Article number: 6857, pp. 1 - 18 [articolo]Open Access
Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.; De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A., Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells, «FRONTIERS IN ONCOLOGY», 2020, 10, Article number: 1225, pp. 1 - 17 [articolo]Open Access
Napolitano R.; de Matteis S.; Carloni S.; Bruno S.; Abbati G.; Capelli L.; Ghetti M.; Bochicchio M.T.; Liverani C.; Mercatali L.; Calistri D.; Cuneo A.; Menon K.; Musuraca G.; Martinelli G.; Simonetti G., Kevetrin induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells, «ONCOLOGY REPORTS», 2020, 44, pp. 1561 - 1573 [articolo]Open Access
Martelli M.; Monaldi C.; De Santis S.; Bruno S.; Mancini M.; Cavo M.; Soverini S., Recent advances in the molecular biology of systemic mastocytosis: Implications for diagnosis, prognosis, and therapy, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2020, 21, Article number: 3987, pp. 3987 - 4007 [articolo]Open Access
Simonetti, G; Malferrari, M; Becconi, M; Bruno, S; Martinelli, G; Rapino, S, Acute myeloid leukemia cell and stem-progenitor cell behavior studied in mimetic bone marrow microenvironment, «CANCER RESEARCH», 2019, 79, pp. 1914 - 1914 [abstract]Open Access
Simonetti, Giorgia*; Padella, Antonella; do Valle, Italo Farìa; Fontana, Maria Chiara; Fonzi, Eugenio; Bruno, Samantha; Baldazzi, Carmen; Guadagnuolo, Viviana; Manfrini, Marco; Ferrari, Anna; Paolini, Stefania; Papayannidis, Cristina; Marconi, Giovanni; Franchini, Eugenia; Zuffa, Elisa; Laginestra, Maria Antonella; Zanotti, Federica; Astolfi, Annalisa; Iacobucci, Ilaria; Bernardi, Simona; Sazzini, Marco; Ficarra, Elisa; Hernandez, Jesus Maria; Vandenberghe, Peter; Cools, Jan; Bullinger, Lars; Ottaviani, Emanuela; Testoni, Nicoletta; Cavo, Michele; Haferlach, Torsten; Castellani, Gastone; Remondini, Daniel; Martinelli, Giovanni, Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery, «CANCER», 2019, 125, pp. 712 - 725 [articolo]Open Access
Simonetti G.; Bruno S.; Padella A.; Tenti E.; Martinelli G., Aneuploidy: Cancer strength or vulnerability?, «INTERNATIONAL JOURNAL OF CANCER», 2019, 144, pp. 8 - 25 [articolo]Open Access
Bruno S.; Bochicchio M.T.; Franchini E.; Padella A.; Marconi G.; Ghelli Luserna Di Rora A.; Venturi C.; Raffini M.; Prisinzano G.; Ferrari A.; Bandini L.; Robustelli V.; Pazzaglia M.; Fontana M.C.; Sartor C.; Abbenante M.C.; Papayannidis C.; Soverini S.; Ottaviani E.; Simonetti G.; Martinelli G., Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia, «JOURNAL OF ONCOLOGY», 2019, 2019, Article number: 5985923, pp. 1 - 8 [articolo]Open Access
Padella A.; Simonetti G.; Paciello G.; Giotopoulos G.; Baldazzi C.; Righi S.; Ghetti M.; Stengel A.; Guadagnuolo V.; De Tommaso R.; Papayannidis C.; Robustelli V.; Franchini E.; Di Rora A.G.L.; Ferrari A.; Fontana M.C.; Bruno S.; Ottaviani E.; Soverini S.; Storlazzi C.T.; Haferlach C.; Sabattini E.; Testoni N.; Iacobucci I.; Huntly B.J.P.; Ficarra E.; Martinelli G., Novel and rare fusion transcripts involving transcription factors and tumor suppressor genes in acute myeloid leukemia, «CANCERS», 2019, 11, pp. 1951 - 1972 [articolo]Open Access
Di Rora A.G.L.; Bocconcelli M.; Ferrari A.; Terragna C.; Bruno S.; Imbrogno E.; Beeharry N.; Robustelli V.; Ghetti M.; Napolitano R.; Chirumbolo G.; Marconi G.; Papayannidis C.; Paolini S.; Sartor C.; Simonetti G.; Yen T.J.; Martinelli G., Synergism through WEE1 and CHK1 inhibition in acute lymphoblastic leukemia, «CANCERS», 2019, 11, pp. 1654 - 1670 [articolo]Open Access
D. Sollazzo, D. Forte, G. Simonetti, S. Bruno, M. Barone, G. Auteri, E. Ottaviani, M. Romano, G. Martinelli, N. Vianelli, M. Cavo, F. Palandri, L. Catani, CIRCULATING CD34+ STEM/PROGENITOR CELLS FROM TRIPLE NEGATIVE PATIENTS WITH MYELOFIBROSIS SHOW DIFFERENT NUMBER, GENE EXPRESSION PROFILE AND IN VITRO RESPONSE TO INFLAMMATORY STIMULI AS COMPARED WITH THE JAK2(V617F) MUTATED COUNTERPARTS, in: Haematologica XV Congress of the Italian Society of Experimental Hematology Rimini, Italy, October 18-20, 2018 ABSTRACT BOOK, 2018(atti di: XV Congress of the Italian Society of Experimental Hematology, Rimini, Italy, October 18-20, 2018) [atti di convegno-poster]
do Valle, Ítalo Faria; Menichetti, Giulia; Simonetti, Giorgia; Bruno, Samantha; Zironi, Isabella; Durso, Danielle Fernandes; Mombach, José C M; Martinelli, Giovanni; Castellani, Gastone; Remondini, Daniel, Network integration of multi-tumour omics data suggests novel targeting strategies, «NATURE COMMUNICATIONS», 2018, 9, pp. 4514 - 4523 [articolo]Open Access
Jacopo Nanni, Giorgia Simonetti, Giovanni Marconi, Maria Chiara Fontana, Samantha Bruno, Cristina Papayannidis, Antonella Padella, Mariachiara Abbenante, Silvia lo Monaco, Elena Tenti, Chiara Sartor, Sarah Parisi, Giovanni Martinelli, A Three-Genes Signature of Anti-Apoptotic Genes Showed Different Mechanisms in Preventing Apoptosis in Acute Myeloid Leukemia Cells and Could Provide an Useful Model to Establish the Proper BH3-Mimetich Drug or Combination, «BLOOD», 2017, 130, pp. 4969 - 4969 [abstract]
Giorgia Simonetti, Samantha Bruno, Carmine Onofrillo, Marco Malferrari, Cristina Papayannidis, Giovanni Marconi, Michele Cavo, Stefania Rapino, Lorenzo Montanaro, Giovanni Martinelli, Bromodomain Inhibition Is Effective Against Acute Myeloid Leukemia Cells Under Hypoxia and Induces Genome-Dependent Metabolic Perturbations, «BLOOD», 2017, 130, pp. 3936 - 3936 [abstract]
Antonella Padella, Giorgia Simonetti, Maria Chiara Fontana, Marco Manfrini, Giovanni Marconi, Anna Ferrari, Italo Faria do Valle, Marianna Garonzi, Cristina Papayannidis, Eugenia Franchini, Elisa Zuffa, Viviana Guadagnuolo, Samantha Bruno, Andrea Ghelli Luserna di Rorà, Emanuela Ottaviani, Daniel Remondini, Massimo Delledonne, Giovanni Martinelli, Co-occurrence of alterations in the DNA damage repair genes synergize with uncontrolled proliferation and associate with very-poor prognosis in acute myeloid leukemia patients, «CANCER RESEARCH», 2017, 77, pp. 4671 - 4671 [abstract]
