Foto del docente

Massimo Cocchi

Adjunct professor

Department of Veterinary Medical Sciences

Curriculum vitae

CURRICULUM VITAE

Massimo Cocchi

Massimo Cocchi was born in Bologna on October 8, 1945.

Massimo Cocchi graduated in Medicine and Surgery in 1971 from the University of Bologna.

He builds his scientific career at the Institute of Biological Chemistry of the same University, mainly dealing with Biochemistry of Nutrition.

In 1977/78 he was entrusted with the task of teaching Food Science at the School of Tourism Studies of the Faculty of Economics and Commerce of the University of Bologna.

In 1990 he was appointed honorary professor of Biochemistry of Nutrition at the Scottish Agricultural College.

In 1995 he was appointed Full Professor of Biochemistry of Nutrition at the Scottish Agricultural College (Glasgow University).

In 1998 he received the title of Professor in Perpetual of the Scottish Agricultural College.

From 2003 to 2009 he was President of the Scientific Association "ARNA", Association of Nutrition and Food Researchers.

In 2005 he was appointed Contract Professor of Food and Human Nutrition at the Faculty of Veterinary Medicine of the University of Bologna, a position he still holds.

In 2005 he was appointed President of the Italian Society of Experimental Biology, Section of Bologna "Oliviero Mario Olivo".

In 2005 he began, with Lucio Tonello, to study platelet fatty acids in groups of patients (depressed and ischemic) by creating a combination between biochemistry and artificial neural network that allowed to identify the population with depressive and ischemic pathology compared to apparently normal subjects .

For this research, in 2008 he received the Kioto Prize nomination.

Since 2010 he has been a member of the Quantum Paradigm Psychopathology Group (QPP).

In 2016 he was appointed President of the Italian Society of Experimental Biology.

In 2014 he was appointed Corresponding Member and in 2017 Ordinary Member of the Accademia dei Georgofili.

In 2019 he was proposed and approved as Honorary President of the Italian Society of Experimental Biology.

In 2020 he was appointed Member of the Academy of Medical Sciences of Palermo.

Currently Massimo Cocchi is president of the QPP Institute: "Research Institute for Quantitative and Quantum Dynamics of Living Organisms. Center for Medicine, Mathematics & Philosophy Studies".

Without ever abandoning scientific work, the publication of essays begins, including the "Arrow of the Archer", "In front of Life," of Man, of Consciousness, psychiatric card "," Even genes have a chicken brain "For the types of Plumelia Edizioni," La Vita Stanca "for the types of Manni Editore.

Always for the types of Plumelia Edizioni, in the "T'ang" dimension, "Pensieri Spezzati", "D'Altri spezzati", "Nel Tempo, Nei Pensieri" (archived at the Fardelliana library in Trapani) subsequently, always for the types of Plumelia he publishes "Ballarò e l’Assimetria".

In 2018, he participated, with an unpublished story, "Quel Pugno di Terra bastarda", at the XXXIV Literary Prize of the Italian Cultural Institute of Naples and won the Literature Prize, subsequently published for the types of ICI editions. In 2019, for the types of Oil Officina Edizioni, he published "La Valigia dei Ricordi" and in 2020 "Brief Dialogue On Nature and Man, between Philosophy and Science".

Research topics

1) Ethanol and lipids

2) Studies concerning unusual fatty acids

3) Food lipids and tissue lipids

4) Studies on essential fatty acids (EFA)

5) Fatty acids of the n-6 and n-3 series

6) Cellular nutrition

7) Lipid metabolism during development and growth

8) Molecular aspects in Psychiatry

9) Molecular aspects in ischemic heart disease

10) Gut microbiota

1) Metabolism of ethanol and lipids

The effect of ethanol on lipid homeostasis has been studied in the rat liver. Phospholipidic fractions and related modifications of fatty acids were dose-dependent in relation to the extent of ethanol intake. At an early stage, this phenomenon was reversible, since ethanol was excluded from the diet, but if at the same time the animals received a hypoprotein diet, which worsened biochemical damage, a return to normal was not possible. The influence of cells grown with ethanol was studied by evaluating cell growth and respiration in the presence of different concentrations of ethanol.

2) Studies concerning unusual fatty acids

 Studies conducted on both experimental animals and men have confirmed concerns about the use of oils containing a large percentage of erucic acid (C 22: 1 n-9), responsible for some biochemical, functional and anatomical changes in the heart, where the intake of this acid could induce histiocytic infiltrations. These investigations demonstrated the presence of C 22: 1 n-9 in the rat heart, both in whole and in the phospholipidic fractions. Serum studies have shown that the dietary intake of rapeseed and rapeseed affects the acidic composition of plasma lipids, changing their acidic profile also in humans. The results obtained with these experimental studies were submitted to the Ministerial Committee, to determine the rules of use for the use of the oils mentioned above. In addition, the influence of trans fatty acid intake on the acid composition of different organs (adipose tissue, heart, liver etc.) was investigated. The increase in the consumption of hydrogenated fats in the diet, containing these non-physiological isomers, motivated these studies. The results showed an accumulation of trans fatty acids in the organs considered, even if in different percentages, not proportional to the intake of these isomers. The administration of a large amount of trans fatty acids also affects the level of fatty acids and cholesterol in plasma. As regards the influence of these stereoisomers on the respiratory activity of the mitochondria of the heart, it has been noted that, in particular stress conditions, mitochondrial activity has decreased, probably in relation to the presence of trans fatty acids in cardiac phospholipids.

3) Food lipids and tissue lipids
Researches on dietary and tissue lipid correlations have been performed on rats at different times (60, 120, 180 and 360 days) up to a maximum of 540 days, in order to evaluate the effects of long-term treatment. It has been pointed out that not only the stored lipids have been influenced by dietary modifications, but also the cellular lipids can be influenced later. Even the brain lipids, generally considered constant, have changed according to the different dietary fatty acids. This concerned not only glyceride but also the phospholipidic fraction. The same changes have been observed in the heart, liver, muscles and blood. Significant changes in total lipids, phospholipids and fatty acid composition have been observed in mitochondria, microsomes and, to a lesser extent, in the nucleus of hepatocytes. In order to clarify the modifications of lipid and coenzyme Q10, different diets have been used, such as the alipidic (Dewel), hypercholesterolemic (Peifer) and vitamin E deficient (Edwin) diets. All these diets caused a noticeable decrease in Coenzyme Q10, especially in the heart. The lipid content and pattern of fatty acids have also been studied in Rinolophus ferrum aequinum during hibernation. The results showed a decrease in the total lipid content, with percentage changes detectable in the composition of fatty acids. In particular, essential fatty acids (EFA) and oleic acid have decreased while saturated fatty acids have increased and no changes have been observed in the brain.

4) The metabolism of long chain fatty acids in ruminants
Some studies conducted on sheep have shown that the fatty acids present in the rumen are different from those present in the diet and that the hydrogenation of linoleic and linolenic acid and a new biosynthesis of branched fatty acids occurs. The "in vitro" calculation of the biosynthesis of long chain fatty acids in sheep's rumen was possible using an alipidic diet. Not only was the presence of branched fatty acids demonstrated, but also the biosynthesis of linoleic acid.

5) Fatty acids of the n-6 and n-3 series
The most recent knowledge on polyunsaturated fatty acids related to the problem related to n-6 and n-3 fatty acids. These fatty acids are very important not only for their role in the composition of the cellular and sub-cellular structure, but also as precursors of prostanoids, which have important and differentiated physiological functions. In particular, gamma-linolenic acid (n-6) is very effective in modulating the balance between aggregating and non-aggregating prostaglandins, supporting the synthesis of PGEI at the expense of PGE2. The higher fatty acids of the alpha-linolenic family (n-3) have a fundamental structural function in the brain, retina, gonads, etc. Research conducted in this field has provided greater knowledge of the metabolic turnover of the fatty acids abaut n-6 and n-3, the correlations between the fatty acids of the two series with respect to quantity, as well as their competition with specific elongation enzymes and desaturation. In particular, some differences have been reported in the acidic composition of rats fed diets having different quantities of n-6 and n-3 fatty acid. These differences were also observed in mitochondria, but had no influence on their functionality, since mitochondrial respiratory activity appeared to be normal. The dietary intake of alpha-linolenic acid seems to be very important for the nervous system. Following the intake of alpha-linolenic, some structural changes are detectable, both in the brain "in toto" and in individual structures such as the optic nerve and the trigeminal nerve. C 18: 3 n-3 metabolism was also observed in the chicken embryo. The area of biosynthesis of specific fatty acids in the maturation phase has been reported to move to particular organs at the end of the embryo's growth period.

6) Studies on essential fatty acids (EFA)
Some investigations have attempted to determine EFA's needs
The results obtained in the experimental animals (rats) showed that the greater requirement of EFA corresponded to the central period of life, being higher for men than for women. This made it possible to evaluate EFA requirements on the basis of tissue lipid homeostasis and the pattern of total fatty acids. Large intake of EFA initially led to an increase in unsaturation of fatty acids in all tissues, including the brain, and in subcellular structures, such as hepatic mitochondria. Subsequently, the phenomenon decreased and the biochemical aspect of these structures returned to normal. This seemed to show a tissue defense mechanism against too high EFA quantities. The adipose tissue also had its own homeostatic control and did not accumulate, in these experimental conditions, essential fatty acids beyond a defined limit. In contrast, collateral research using EFA-deficient diets has shown alterations in spontaneous and provoked motility in experimental animals and, furthermore, a decrease in learning ability and in recent and remote memory.

7) Cellular nutrition
This line of research was performed on chicken embryonic myocardial cells. The effects of various nutrients, such as carbohydrates, ethanol and phospholipids on the proliferation and respiratory activity of the myocardial cells of chicken embryos, cultured in suspension, were evaluated. The addition of phospholipids to cultures, at low concentrations, showed a positive effect on cell growth, both under basal conditions and in stress conditions while at higher concentrations, the phospholipids seemed to be negative as well as  the phospholipids  
of cardiac origin inhibited the growth of cell cultures of embryonic chicken myocardium. These results differed in relation to the organ from which the phospholipids were extracted, and this was well correlated with some clinical studies based on the enteral or parenteral phospholipid intake in men. In short, it has been shown that exogenous phospholipids, at appropriate concentrations, can stimulate the speed of macromolecular synthesis processes, enhancing the action of serum growth factors in cultured cells. As for the mechanism of action of phospholipids, this seems to be exercised through the modulation of some endogenous factors, such as cyclic nucleotides (AMPc and GMPc) and polyamines (putrescine, spermidine, spermine), closely involved in the regulation of biochemical processes relevant, related to the growth rate and cell division.

8) Changes in lipid metabolism during development and growth.
The tissues of the developing chicken embryo show particularly high levels of C20 and C22 polyunsaturated fatty acids. These fatty acids are derived during the lipid absorption of the yolk by synthesis inside the membrane of the yolk sac and there is a preferential absorption of phosphatidyl-ethanolamine. The yolk contains a limited level of vitamin E. The marked increase in double bonds associated with the accumulation of polyunsaturated fatty acids in the tissues of the embryo therefore raises the question of whether adequate levels of vitamin E are maintained in the lipid absorption of the yolk sac to offer protection against peroxidation. The relationship between vitamin E and polyunsaturated fatty acids in the contents of the yolk, the membrane of the yolk sac and the tissues during the development of the chicken embryo was studied.

9) Platelet fatty acids in depressive disorder and ischemic heart disease
In 2005, with Lucio Tonello, the study of platelet fatty acids in groups of patients (depressive and ischemic) began, creating a combination between biochemistry and artificial neural network that allowed to identify the depressed and ischemic population towards apparently normal people.
International recognition has been received on the result obtained with regard to the unequivocal classification of depressed, bipolar and ischemic heart disease subjects.

10) Animal microbiota
The research conducted on the molecular contiguity between man and animal with respect to the psychopathological phenomenon, has made it possible to classify some animal species in their similarity to man.
As a consequence of the results obtained, comparative research was carried out, in particular, between the German Sheferd microbiota, whose molecular profiles corresponding to human depressive psychopathology were known, and that of depressed subjects, finding a high degree of affinity between the two microbiota. This finding has opened further considerations on the microbiota and brain relationship as well as on the role of microbiota sharing in depressive pathology.

Selection from publications

Traina G. and Cocchi M. Mast Cells, Astrocytes, Arachidonic Acid: Do They Play a Role in Depression? Appl. Sci. 2020, 10, 3455.

Cocchi, M., Gabrielli, F., & Gulino, G. Man, Virus, & Bacteria: Conscious or Unconscious Invasion? Journal of Consciousness Exploration & Research| April 2020 | Volume 11 | Issue 3 | pp. 302-305.

Summhammer J, Sulyok G, Bernroider G, and Cocchi M. Forces from Lipids and Ionic Diffusion: Probing lateral membrane effects by an optimized filter region of voltage dependent K+ channels. arXiv. Org. Physics 2020.

Elisabetta Mondo, Alessandra De Cesare, Gerardo Manfreda, Claudia Sala, Giuseppe Cascio, Pier Attilio Accorsi, Giovanna Marliani and Massimo Cocchi. Depression and Microbiome—Study on the Relation and Contiguity between Dogs and Humans. Appl. Sci. 2020, 10, 573.

Cocchi, M., Gabrielli, F., & Gulino, G., Depression between Biology & Mathematics: Does the Word Play a Role? Journal of Consciousness Exploration & Research. February 2020. Volume 11, Issue 2, pp. 198-200.

Massimo Cocchi, Elisabetta Mondo, Chiara Minuto, Giovanni Lercker Linoleic acid: have we understood how it works in Psychopathologies and Ischemic Cardiovascular Diseases? Progress in Nutrition 2020; Vol. 22, N. 1: 7-11.

E. Mondo, M. Barone, M. Soverini, F. D'Amico, M. Cocchi, C. Petrulli, M. Mattioli, G. Marliani, M. Candela, P.A. Accorsi. Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders. Heliyon 6 (2020) e03311.

M. Cocchi, G. Lercker, N. G. Frega, et al. Is a low concentration of Linoleic Acid related to the extended longevity of the Queen honeybee? Progress in Nutrition 2019; Vol.21, N. 4: 729-734.

Massimo Cocchi. In memory of Dr. Kary Mullis. Journal of Biological Research 2019; volume 92:8513.

Tonello, L., Giacobbi, L., Pettenon, A., Scuotto, A., Cocchi, M., Gabrielli, F., & Cappello, G. (2019). Problem behavior in autism spectrum disorders: A paradigmatic self-organized perspective of network structures. Behavioral and Brain Sciences, 42, E28.

Cocchi M, Gabrielli F. No Calculation in Stupor: Beauty as Infinite Surprise. NeuroQuantology. 2019.17, 04: 30-31.

Massimo Cocchi, Lucio Tonello, and Fabio Gabrielli. The issue of depression and the a-quantum consciousness. Remembering a fabulous day - Letter to Psychiatrists. NeuroQuantology, 2019, 17, 08: 01-07.

Cocchi, M., Gabrielli, F., & Tuszynski, J. A., Death: An Unpredictable Variable of Time - Is the Impossible Possible? Scientific GOD Journal | July 2019 | Volume 10 | Issue 5 | pp. 379-383.

Cocchi, M. & Gabrielli, F., On Paternoster: No Longer “Lead Us Not into Temptation” but “Do Not Abandon Us to Temptation”. Scientific GOD Journal | December 2018 | Volume 9 | Issue 8 | pp. 614-616.

Lucio Tonello, Luca Giacobbi, Alberto Pettenon, Alessandro Scuotto, Massimo Cocchi, Fabio Gabrielli, and Glenda Cappello. Crisis Behavior in Autism Spectrum Disorders: A Self-Organized Criticality Approach. Complexity Volume 2018, Article ID 5128157, 7 pages

Tonello L. Gashi B. Scuotto A. Cappello G. Cocchi M. Gabrielli F. Tuszynski J. The gastrointestinal-brain axis in humans as an evolutionary advance of the root-leaf axis in plants: A hypothesis linking quantum effects of light on serotonin and auxin. Journal of Integrative Neuroscience, 2018, 17, 2: 227-237.

Cocchi M, Tonello L, Gabrielli F. Linoleic Acid: fine tuning regulator of mood disorders? The 13th Conference of Italian Researchers in the world, Dallas, TX, USA, 1 December 1st, 2018.

Massimo Cocchi, Chiara Minuto, Lucio Tonello, Fabio Gabrielli, Gustav Bernroider, Jack A. Tuszynski, Francesco Cappello, and Mark Rasenick. Linoleic acid: Is this the key that unlocks the quantum brain? Insights linking broken symmetries in molecular biology, mood disorders and personalistic emergentism. BMC Neurosci (2017) 18:38.

P.A. Accorsi E. Mondo and M. Cocchi. Did you know that your animals have consciousness? Journal of Integrative Neuroscience 16 (2017) S1–S2.

Massimo Cocchi, Fabio Gabrielli, Lucio Tonello and Jack Tuszynski. A dialogue on the issue of the “quantum brain” between consciousness and unconsciousness. Journal of Integrative Neuroscience 16 (2017) S1–S2.

Massimo Cocchi, G. Bernroider, Mark Rasenick, Lucio Tonello, Fabio Gabrielli and Jack A. Tuszynski. Document of Trapani on animal consciousness and quantum brain function: A hypothesis. Journal of Integrative Neuroscience -1 (2017) 1–5.

Massimo Cocchi, Fabio Gabrielli, Lucio Tonello and Jack Tuszynski. A dialogue on the issue of the “quantum brain” between consciousness and unconsciousness. Journal of Integrative Neuroscience -1 (2017) 1–6.

Cocchi, M. & Capezzani, L., Time & Free Will: Concepts & Considerations Scientific GOD Journal | February 2017 | Volume 8 | Issue 2 | pp. 164-166.

P.A. Accorsi, E. Mondo and M. Cocchi. Did you know that your animals have consciousness? Journal of Integrative Neuroscience (2019) 1–9.

Rosario Barone, Francesca Rappa, Filippo Macaluso, Celeste Caruso Bavisotto, Claudia Sangiorgi, Gaia Di Paola, Giovanni Tomasello, Valentina Di Felice, Vito Marcianò, Felicia Farina, Giovanni Zummo, Everly Conway de Macario, Alberto J.L. Macario, Massimo Cocchi, Francesco Cappello, and Antonella Marino Gammazza. Alcoholic Liver Disease: A Mouse Model Reveals Protection by Lactobacillus fermentum. Clinical and Translational Gastroenterology (2016) 7, e138.

Cocchi M, Tonello L, Gabrielli F. Cholesterol on Sunset Boulevard: the decline of a myth. Letter to the Editor. BMJ 2016.

Cocchi M, Minuto C, Tonello L, Tuszynski JA. Connection between the Linoleic Acid and Psychopathology: A Symmetry-Breaking Phenomenon in the Brain? Open Journal of Depression, 2015, 4, 41-52.

Tonello L, Cocchi M, Gabrielli F and Tuszynski JA. On the possible quantum role of serotonin in consciousness. J. Integr. Neurosci. 14, 295 (2015).

Massimo Cocchi, Fabio Gabrielli, Lucio Tonello. Molecular and Quantum Approach to Psychopathology and Consciousness. Ann Depress Anxiety. 2015;2(2): 1046.

Tonello L, Conway de Macario E, Marino Gammazza A, Cocchi M, Gabrielli F, Zummo G, Cappello F, Macario AJ. Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto's thyroiditis patients based on the response of their PBMC with IL-2 and IFN-γ secretion to stimulation with Hsp60. Cell Stress Chaperones. 2014 Nov 19.

Cocchi M, Tonello L. and Gabrielli F. Cell Membrane and Consciousness: A Journey Through Biology, Mathematics and Philosophy. Ann Depress Anxiety. 2014; 1(7): 1035.

Cocchi, M., Tonello, L., Gabrielli, F, Minuto C. Human and Animal Brain Phospholipids Fatty Acids, Evolution and Mood Disorders. J Phylogen Evolution Biol 2014, 2:2.

Benedetti, S., Bucciarelli, S., Canestrari, F., Catalani, S., Mandolini, S., Marconi, V., Mastrogiacomo, A., Silvestri, R., Tagliamonte, M., Venanzini, R., Caramia, G., Gabrielli, F., Tonello, L. and Cocchi, M. (2014) Platelet’s Fatty Acids and Differential Diagnosis of Major Depression and Bipolar Disorder through the Use of an Unsupervised Competitive-Learning Network Algorithm (SOM). Open Journal of Depression, 3, 52-73.

Cocchi, M, Tonello, L. & Gabrielli, F. (2014). Mood Psychopathologies: An Integrated Complexity-Based Interpretation. Psychology, 5: 192-203

Cocchi, M., Tonello, L. & Gabrielli, F. (2014). Psychiatric Doubts. Open Journal of Depression, 3, 5-8.

Cocchi M, Gabrielli F, Tonello L, Delogu M, Beghelli V, et al. (2013) Molecular Contiguity between Human and Animal Consciousness through Evolution: Some Considerations. J Phylogen Evolution Biol 1: 119. doi: 10.4172/2329-9002.1000119

M. Cocchi, F. Gabrielli, L. Tonello, Platelet’s Fatty Acids Secrets in Coronary Artery Disease (CAD), Letter to the Editor, BMJ, October 28th, 2013.

M. Cocchi, L. Tonello, F. Gabrielli, A. Castaldo, “L’unicità molecolare della Depressione Maggiore: considerazioni biologiche e implicazioni teoretiche”, Psichiatria Oggi, XXVI, 1, 2013: 27-34.

Tonello L., Gabrielli F., Cocchi M. (2013). Stream of consciousness: quantum and biochemical assumptions regarding psychopathology. Quantum Biosystems QPP Group, 5: 24-25.

Cocchi M., Gabrielli F., Tonello L. et al. (2013). Consciousness from animals to humans: quantum and molecular pathways. Quantum Biosystems QPP Group, 5: 19-20.

Cocchi M., Gabrielli F., Pessa E., Pregnolato M., Tonello L., Zizzi P., “Major Depression and Bipolar Disorder: The Concept of Symmetry Breaking”. NeuroQuantology. December 2012. Volume 10, Issue 4, Page 676‐687.

Cocchi M., Tonello L., Gabrielli F., “Possible Roles of Cell Membrane & Cytoskeleton in Quantum Aspect of Psychiatry”. Journal of Consciousness Exploration & Research| November 2012 | Volume 3 | Issue 10 | pp. 1082-1100.

Cocchi M., Tonello L., Gabrielli F., “Molecular Uniqueness of Major Depression: Biological Remarks and Theoretical Implications”. Journal of Consciousness Exploration & Research |May 2012 | Vol. 3 | Issue 4 | pp. 380-391

Cocchi M., Tonello L., Gabrielli F., “Considerations on Blood Platelets: A Neuron’s Mirror for Mood Disorders?”. Open Journal of Blood Diseases, 2012, 2, 22-29.

Cocchi M., Tonello L., Gabrielli F., “The Human Aspect of Christ between Classic and Quantum Consciousness: Gethsemane - Anxiety & Depression between Biochemistry & Anthropology”. Scientific GOD Journal | June 2012 | Vol. 3 | Issue 5 | pp. 432-439.

Cocchi M., Tonello L., Gabrielli F., Pregnolato M., "Biological and Anthropological Existential Hypothesis on Depression”. Quantum Biosystems 2011; 3 (1): 12-18.

Cocchi M., Tonello L., Gabrielli F., Pregnolato M., Pessa E., "Quantum Hypothesis on Human and Animal Consciousness: a Concept Embracing Philosophy”, Quantitative Molecular Biology and Mathematics, Journal of Consciousness Exploration & Research, 2, 4, 2011: 547-574.

Cocchi M, Tonello L, Gabrielli F, Pregnolato M, “Depression, osteoporosis, serotonin and cell membrane viscosity between biology and philosophical anthropology”. Annals of General Psychiatry 2011, 10:9 - doi: 10.1186/1744-859X-10-9.

Cocchi M, Tonello L, Gabrielli F, Pregnolato M, “Consciousness and Hallucinations: Molecular Considerations and Theoretical Questions”. NeuroQuantology 2011; 1:182-189.

Cocchi M, Gabrielli F, Tonello L, Pregnolato M, “Interactome hypthesis of Depression”. NeuroQuantology 2010; 4: 603-613

Cocchi M, Tonello L, Lercker G, “Fatty acids, membrane viscosity, serotonin and ischemic heart disease”. Lipids in Health and Disease 2010, 9:97.

Tonello L., Cocchi M, “The Cell Membrane: is it a bridge from psychiatry to quantum consciousness?”. NeuroQuantology 2010; 1:54-60.

Cocchi M. Tonello L., “Running the hypothesis of a bio molecular approach to psychiatric disorder characterization and fatty acids therapeutical choices”, Annals of General Psychiatry, 9 (supplement 1): S26, 2010.

Cocchi M. Tonello L, “Bio molecular considerations in Major Depression and Ischemic Cardiovascular Disease”. Central Nervous System Agents in Medicinal Chemistry. 9: 2-11. 2010.

Cocchi M. Tonello L. Rasenick Mark M. “Human depression: a new approach in quantitative psychiatry”. Annals of General Psychiatry. 2010, 9:25.

Cocchi M., Tonello L., Martínez Álvarez J.R.,” Nutritional considerations on platelet fatty acids in Major Depression and Ischemic Cardiovascular Disease”. Nutr. clín. diet. hosp. 2009; 29(2):46-54.

Cocchi M., Tonello L., De Lucia A., Amato P. “Platelet and Brain Fatty Acids: a model for the classifcation of the animals? Part 1”. International Journal of Anthropology Vol. 24 - n.1 (69-76) – 2009.

Cocchi M., Tonello L., Lercker G.” Platelet Stearic Acid in different population groups: biochemical and functional hypothesis”. Nutr. clín. diet. hosp. 2009; 29(1):34-45.

Tsaluchidu S., Cocchi M., Tonello L., Puri B.K. “Fatty acids and oxidative stress in psychiatric disorders”. BMC Psychiatry 2008, 8(Suppl 1): S5. doi: 10.1186/1471-244X-8-S1-S5.

Puri B. K., Treasaden I. H., Cocchi M., Tsaluchidu S., Tonello L. and Ross B. M. “A comparison of oxidative stress in smokers and non-smokers: an in vivo human quantitative study of n-3 lipid peroxidation”, BMC Psychiatry 2008, 8(Suppl 1): S4. doi: 10.1186/1471-244X-8-S1-S4.

Cocchi M., Tonello L., Tsaluchidu S., Puri B.K. “The use of artificial neural networks to study fatty acids in neuropsychiatric disorders”, BMC Psychiatry 2008, 8(Suppl 1): S3. doi: 10.1186/1471-244X-8-S1-S3.

Cocchi M., Tonello L., Cappello G., Tarozzi G., Nabacino L., Pastorini E., Bucciarelli S., Solazzo L., De Luca M., Visci G., Caramia G.” Membrane platelet fatty acids: biochemical characterisation of the ischemic cardiovascular disease, characteristics of the paediatric age, through an artificial neural network interpretation”. Pediatr Med Chir 2008 Jan-Feb; 30(1):25-30.

Caramia G., Cocchi M., Tonello L., Visci G.,” Children obesity: actualities and experimental contribution”. Pediatr Med Chir 2008 Jan-Feb; 30(1):121-140.

Cocchi M., Tonello L., Cappello G., Bosi S., Cremonesi A., Castriota F., Mercante M., Tarozzi G., Bochicchio D., Della Casa G., Caramia G. “Membrane platelet fatty acids: a model of biochemical characterisation of the ischemic cardiovascular disease, through an artificial neural network interpretation”, Progress in Nutrition, Vol.10, N. 1, 48-52, 2008.

Cocchi M., Mordenti A. L., Merendi F., Sardi L., Tonello L., Bochicchio D., Faeti V., Della Casa G., Tarozzi G. “Pig platelet fatty acids composition in different lipid treatments”, Progress in Nutrition, Vol.10, N. 1, 53-57, 2008.

Cocchi M., Tonello L., “Platelets, Fatty Acids: a model for the classification of the animal world?”, Progress in Nutrition. Vol.10, N. 1, 58-64, 2008.

Cocchi M., Tonello L., “Platelets, Fatty Acids, Depression and Cardiovascular Ischemic Pathology”, Progress in Nutrition. Vol.9, N. 2, 94-104, 2007.

Cocchi M., Tonello L., Cappello G., Nabacino L., Passi S., Baldini N., Soreca I., Paffetti I., Castrogiovanni P., Tarozzi G., “Biochemical Markers in Major Depression as interface between Neuronal Network and Artificial Neural Network (ANN)”, J. Biol. Res. LXXXI, 77-81, 2006.

Cocchi M., Tonello L., “Biological, Biochemical and Mathematical considerations about the use of an Artificial Neural Network (ANN) for the study of the connection between Platelet Fatty Acids and Major Depression”, J. Biol. Res. LXXXI, 82-87, 2006.

Massimo Cocchi LA CENTRALITÀ BIOLOGICA DELLA DONNA E IL PROGETTO VITALE. 2004. La Rivista Italiana di Ostetricia e Ginecologia - Vol. 1 - pp. 3-4.

Books:

Massimo Cocchi. Anche i geni hanno un cervello di "gallina": la "rottura di simmetria" vale per tutti. Plumelia, 2017.

M. Cocchi, F. Gabrielli, A. Gerbino, L. Tonello. 2016. Di fronte alla vita. Plumelia Edizioni. isbn: 978-88-89876-24-4.

Giannelli, A. Castaldo, F. Gabrielli, L. Tonello, M. Cocchi. Dell’uomo, della coscienza. Carta Psichiatrica, Plumelia, Palermo 2013.

M. Cocchi, F. Gabrielli, L. Tonello, “La freccia dell’arciere”. Ipotesi biologiche e letture antropologico-esistenziali della vita, Plumelia, 2013.

R. E. Baroudi, M. Cocchi, A. De Filippo, F. Gabrielli, G. Galimberti, M. Jaeggi, A. Mangone, A. Scuotto, S. Stornelli, L. Tonello, Il Metodo Swing By. Uno strumento per analizzare e governare la complessità, versione Italiano-Inglese, Ludes University Press, Lugano 2013.

M. Cocchi, L. Tonello, F. Gabrielli, A. Castaldo, Music, Brain, Consciousness, Ludes University Press, Lugano 2013.

Massimo Cocchi, Fabio Gabrielli, Vincenzo Guarracino, Lucio Tonello. “La Vita Stanca – sguardi multidisciplinari sulla depressione”. Manni Editore. PP 320. Lecce, 2013 In Italian only. ISBN 978-88-6266-486-8

Massimo Cocchi, Fabio Gabrielli, Lucio Tonello. “Collection of scientific papers in memory of Paolo Sotgiu”. LUdeS University Press, 2012. ISBN: 978-88-6047-026-3. Italian version: "Raccolta di scritti scientifici in memoria di Paolo Sotgiu".

Massimo Cocchi, Lucio Tonello, Fabio Gabrielli. “The animal side of ‘mood disorders’”, LAP Lambert Academic Publishing, October 2011. ISBN: 978-3-8465-2094-9.

Massimo Cocchi, Fabio Gabrielli, Lucio Tonello. “The Melancholic Platelets – Biological experimental route and existential notes about major depression”. Lugano; L.U.de.S. UNIVERSITY PRESS, Sept. 2009. Italian / English. ISBN 978-88-6047-014-X.


Massimo Cocchi, Sette anni a spasso con il nobel Kary Mullis, 2008, CLUEB.

Massimo Cocchi e Lucio Tonello. “Depressione Maggiore e Patologia Cardiovascolare Ischemica. Un Network fra piastrine, cuore e cervello. Reti Neurali Artificiali, potenzialità predittiva di alcuni acidi grassi della membrana piastrinica”. Bologna; CLUEB, 2007. 205 p; ill; 24 cm. Italian. ISBN 978-88-491-3005-8. (Second Edition Available).


Massimo Cocchi [https://www.libraccio.it/autore/massimo-cocchi/libri.html] . Scienza dell'alimentazione. 1982, CLUEB [https://www.libraccio.it/editore/clueb/libri.html] .

Short Monographic Papers

M. Cocchi, L. Tonello, F. Gabrielli et al., “I segreti dell’acido linoleico. Evidenze, interpretazioni, ipotesi”. Ludes University Press, Lugano 2014.

Massimo Cocchi, Lucio Tonello, Fabio Gabrielli, Francesco Cappello, Mark M. Rasenick. “Serotonina, Infiammazione Intestinale, Microbiota – Una “Road Map” tra cervello e intestino nei disordini dell’umore: una lettura biologica ed antropologica.” LUdeS University Press, 2013. ISBN: 978-88-6047-064-5.

Massimo Cocchi, Giovanni Lercker, Fabio Gabrielli, Lucio Tonello, Francesco Cappello, Manfredi Rizzo, Bill Gallanter. “Il colesterolo.” LUdeS University Press, 2013. ISBN: 978-88-6047-063-8.

Massimo Cocchi, Fabio Gabrielli, Lucio Tonello. “Major Depression, A Journey Between Biology and Anthropology” LUdeS University Press, June 2011. ISBN: 978-88-6047-021-8. Italian version: "La Depressione maggiore tra biologia e antropologia".

Book chapters

Massimo Cocchi, Lucio Tonello and Fabio Gabrielli, “Platelet, Fatty Acids, Membrane Viscosity, Depression and Ischemic Heart Disease-Biological-molecular-Path with Medical-Anthropology Insights” in “Coronary Angiography - Advances in Noninvasive Imaging Approach for Evaluation of Coronary Artery Disease”, InTech [http://www.intechweb.org/], September 2011, ISBN 978-953-307-675-1.

Cocchi M, Tonello L. and Gabrielli F. (2015). The Molecular and Quantum Approach to Psychopathology and Consciousness — From Theory to Experimental Practice. June 2015, Chapter 3, INTECH ed. http://dx.doi.org/10.5772/59392.

 

 

 

 

 

 

 

 

 

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