Foto del docente

Maria Carla Re

Professor

Department of Experimental, Diagnostic and Specialty Medicine - DIMES

Academic discipline: MED/07 Microbiology and Clinical Microbiology

Research

Keywords: HIV-1 Genotypic resistance in peripheral blood lymphocyt Genotypic resistance in plasma HIV Tropism DNA viral load avidity test osteopenia/osteoporosis comorbidity RNA viral load HTLV-1/2 Genotypic resistance in resting CD4

Research activities.  Research activities have focused on viral pathogenetic mechanisms and diagnosis of infection mostly human immunodeficiency virus type 1-2 and other retroviruses (HTLV-I/II).

In particular:

·          Development of innovative serological and virological methods for viral infection diagnosis

·          Study and determination of HIV-1 tropism by using genotypic tests to establish viral coreceptor usage

·          Analysis of evolution and population dynamics of HIV-1 during the course of the infection  and HIV-1 transmission epidemiological network

·          Studies of mechanisms regarding the pathogenesis of HIV-1-induced lesions at the haematopoietic stem/progenitor cell level

·          Analysis of pathogenetic role of extracellular Tat and gp120 proteins in the evolution of HIV-1 infection.

·          Analysis of mechanisms involved in bone abnormalities during the course of HIV infection;

·          Analysis of Interaction between HIV-1 and vascular wall resident human mesenchymal stem cells (MSCs); genesis of vessel damage observed in HIV-infected patients.

 

 



·          Development of innovative serological and virological methods for viral infection diagnosis

·          Study and determination of HIV-1 tropism by using genotypic tests to establish viral coreceptor usage

·          Analysis of evolution and population dynamics of HIV-1 during the course of the infection  and HIV-1 transmission epidemiological network

·          Studies of mechanisms regarding the pathogenesis of HIV-1-induced lesions at the haematopoietic stem/progenitor cell level

·          Analysis of pathogenetic role of extracellular Tat and gp120 proteins in the evolution of HIV-1 infection.

·          Analysis of mechanisms involved in bone abnormalities during the course of HIV infection;

·          Analysis of Interaction between HIV-1 and vascular wall resident human mesenchymal stem cells (MSCs); genesis of vessel damage observed in HIV-infected patients.

 

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