F. Chiarini; A. Lonetti; G. Teti; E. Orsini; D. Bressanin; A.Cappellini; F. Ricci; P. L. Tazzari; A. Ognibene; M. Falconi; P. Pagliaro; I. Iacobucci; G. Martinelli; S. Amadori; J.A. McCubrey; A.M. Martelli., A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia., «ONCOTARGET», 2012, 3, pp. 1615 - 1628 [articolo]
Alberto M Martelli;Francesca Chiarini;Camilla Evangelisti;Andrea Ognibene;Daniela Bressanin;Anna Maria Billi;Lucia Manzoli;Alessandra Cappellini;James A McCubrey, Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies, «EXPERT OPINION ON THERAPEUTIC TARGETS», 2012, 16, pp. 729 - 742 [articolo]
A.M. Martelli; F. Chiarini; C. Evangelisti; A. Cappellini; F. Buontempo; D. Bressanin; M. Fini; J.A. McCubrey, Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment., «ONCOTARGET», 2012, 3, pp. 371 - 394 [articolo]
A.M. Martelli; V. Papa; P.L. Tazzari; F. Ricci; C. Evangelisti; F. Chiarini; C. Grimaldi; A. Cappellini; G. Martinelli; E. Ottaviani; P. Pagliaro; S. Horn; J. Bäsecke; L.H. Lindner; H. Eibl; J.A. McCubrey., Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms., «LEUKEMIA», 2010, 24, pp. 687 - 698 [articolo]
A.M. Martelli; C. Evangelisti; F. Chiarini; C. Grimaldi; A. Cappellini; A. Ognibene; J.A. McCubrey., The emerging role of the phosphatidylinositol 3-kinase/Akt/mTOR signaling network in normal myelopoieis and leukemogenesis., «BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH», 2010, 1803, pp. 991 - 1002 [articolo]
A. Cappellini; F. Chiarini; A. Ognibene; J.A. McCubrey; A.M. Martelli, The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage, «CELL CYCLE», 2009, 8, pp. 1421 - 1425 [articolo]
Contestabile A; Fila T; Cappellini A; Bartesaghi R; Ciani E, Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome., «CELL PROLIFERATION», 2009, 42, pp. 171 - 181 [articolo]
V. Papa; P.L. Tazzari; F. Chiarini; A. Cappellini; F. Ricci; A.M. Billi; C. Evangelisti; E. Ottaviani; G. Martinelli; N. Testoni; J.A. McCubrey; A.M. Martelli, Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells, «LEUKEMIA», 2008, 22, pp. 147 - 160 [articolo]
Falà F; Blalock WL; Tazzari PL; Cappellini A; Chiarini F; Martinelli G; Tafuri A; McCubrey JA; Cocco L; Martelli AM, Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-ami
ne (A443654) in T-cell acute lymphoblastic leukemia., «MOLECULAR PHARMACOLOGY», 2008, 74, pp. 884 - 895 [articolo]
Salaroli R.; Di Tomaso T.; Ronchi A.; Ceccarelli C.; Cammelli S.; Cappellini A.; Martinelli GN.; Barbieri E.; Giangaspero F.; Cenacchi G., Radiobiologic response of medulloblastoma cell lines: involvement of beta-catenin?, «JOURNAL OF NEURO-ONCOLOGY», 2008, 90, pp. 243 - 251 [articolo]
Chiarini F.; Del Sole M.; Mongiorgi S.; Gaboardi G.C.; Cappellini A.; Mantovani I.; Follo M.Y.; McCubrey J.A.; Martelli A.M., The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resisten human T-acute leukemia cells by a JNK-dependent mechanism, «LEUKEMIA», 2008, 22, pp. 1106 - 1116 [articolo]
Tazzari P.L.; Cappellini A.; Ricci F.; Evangelisti C.; Papa V.;Grafone T.;
Martinelli G.; Conte R.; Cocco L.; McCubrey J.A.; Martelli A.M., Multidrug resistance-associated protein 1 expression is under the control of
the phosphoinositide 3 kinase/Akt signal transduction network in human acute
myelogenous leukemia blasts., «LEUKEMIA», 2007, 21, pp. 427 - 438 [articolo]
Follo, Matilde Y.; Mongiorgi, Sara; Bosi, Costanza; Cappellini, Alessandra; Finelli, Carlo; Chiarini, Francesca; Papa, Veronica; Libra, Massimo; Martinelli, Giovanni; Cocco, Lucio; Martelli, Alberto M., The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation, «CANCER RESEARCH», 2007, 67, pp. 4287 - 4294 [articolo]
Mantovani I; Cappellini A; Tazzari PL; Papa V; Cocco L; Martelli AM, Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells, «JOURNAL OF CELLULAR PHYSIOLOGY», 2006, 207, pp. 836 - 844 [articolo]
Nyakern M.; Cappellini A.; Mantovani I.; Martelli A.M., Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways, «MOLECULAR CANCER THERAPEUTICS», 2006, 5, pp. 1559 - 1570 [articolo]
