Foto del docente

Alberto Leoni

Professore associato confermato

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Pubblicazioni

Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.; Pagano B.; Randazzo A.; Amato J.; Capranico G., Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 12055 - 12067 [articolo]

Francesca Bonvicini, Alessandra Locatelli, Rita Morigi, Alberto Leoni, Giovanna Angela Gentilomi, Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity, «MOLECULES», 2022, 27, pp. 5781 - 5792 [articolo]Open Access

Gotti R.; Leoni A.; Fiori J., Evaluation of roasting effect on selected green tea volatile flavor compound and pyrazine content by hs-spme gc-ms, «APPLIED SCIENCES», 2021, 11, Article number: 8217, pp. 1 - 12 [articolo]Open Access

Morigi R.; Catanzaro E.; Locatelli A.; Calcabrini C.; Pellicioni V.; Leoni A.; Fimognari C., Synthesis and biological evaluation of new bis-indolinone derivatives endowed with cytotoxic activity, «MOLECULES», 2021, 26, Article number: 6277, pp. 1 - 15 [articolo]Open Access

Amato J.; Miglietta G.; Morigi R.; Iaccarino N.; Locatelli A.; Leoni A.; Novellino E.; Pagano B.; Capranico G.; Randazzo A., Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells, «JOURNAL OF MEDICINAL CHEMISTRY», 2020, 63, pp. 3090 - 3103 [articolo]

Emanuela Pesce, Nicoletta Pedemonte, Alberto Leoni, Alessandra Locatelli, Rita Morigi, Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis., «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2020, 30, Article number: 127473, pp. 1 - 7 [articolo]

Alessandra Locatelli, Luisa Iommarini, Alessandra Graziadio, Alberto Leoni, Anna Maria Porcelli, Stefano Iotti, Emil Malucelli, Francesco Francia, Giovanni Venturoli, Giovanna Farruggia, Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose, «RSC ADVANCES», 2019, 9, pp. 15350 - 15356 [articolo]Open Access

Morigi, R., Locatelli, A., Leoni, A., Rambaldi, M., Bortolozzi, R., Mattiuzzo, E., Ronca, R., Maccarinelli, F., Hamel, E., Bai, R., Brancale, A., Viola, G., Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 166, pp. 514 - 530 [articolo]Open Access

Conti, Ilaria; Morigi, Rita; Locatelli, Alessandra*; Rambaldi, Mirella; Bua, Gloria; Gallinella, Giorgio; Leoni, Alberto, Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19, «MOLECULES», 2019, 24, Article number: 1037, pp. 1 - 15 [articolo]Open Access

Leoni, Alberto; Frosini, Maria; Locatelli, Alessandra; Micucci, Matteo; Carotenuto, Claudio; Durante, Miriam; Cosconati, Sandro; Budriesi, Roberta*, 4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 169, pp. 89 - 102 [articolo]Open Access

Leoni, Alberto; Budriesi, Roberta; Poli, Ferruccio; Lianza, Mariacaterina; Graziadio, Alessandra; Venturini, Alice; Broccoli, Massimiliano; Micucci, Matteo, Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters, «NATURAL PRODUCT RESEARCH», 2018, 32, pp. 2139 - 2146 [articolo]

Morigi, Rita; Vitali, Beatrice; Prata, Cecilia; Palomino, Rogers A. A; Graziadio, Alessandra; Locatelli, Alessandra; Rambaldi, Mirella; Leoni, Alberto, Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora, «MEDICINAL CHEMISTRY», 2018, 14, pp. 311 - 319 [articolo]

R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo, Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents, in: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens. 26th - 28th September 2018 - Padova, Italy - Abstract Book, Padova, 2018, pp. 126 - 126 (atti di: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens., Padova, 26-28 settembre 2018) [atti di convegno-abstract]

Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella, A Patent Review on Thiazole Derivatives (2008-2013), «ACTA CHIMICA & PHARMACEUTICA INDICA», 2017, 7, Article number: 103, pp. 1 - 35 [articolo]

Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella, Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective, «BIOENERGETICS», 2017, 6, Article number: Chemistry Journals-17-99R1, pp. 1 - 3 [articolo]