Treatment of neurodegenerative ophthalmological diseases

The product, possibly an eye-drop, would be used as a treatment to reduce damages to neuronal cells caused by degenerative ophthalmological diseases (such as Glaucoma)

Patent title Blood serum for use in the treatment of neurodegenerative ophthalmological pathologies
Thematic area Health
Ownership ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA, Azienda Ospedaliera- Universitaria di Bologna Policlino S. Orsola- Malpighi, Università degli Studi dell'Aquila
Inventors SILVIA BISTI, MARINA BUZZI, CLAUDIO VELATI, Piera Versura, Emilio Campos
Protection Italy, Canada, China, Japan, Europe, US
Licensing status Available for development agreements, option, license and other exploitation agreements
Keywords Cord blood serum, Retinal degenerative diseases, Glaucoma, Optic nerve degenerative diseases, Retina
Filed on 15 June 2017

Currently, the neuroprotective treatment of degenerative ophthalmological diseases is proposed through the administration of food supplements products or compounds of vegetal origin or specific synthetic molecules.

The invention refers to the ophthalmic use of cord blood serum (CBS) in the treatment of degenerative diseases of the retina and the optic nerve, such as glaucoma. The product to be developed in the form of an eye-drop, will have a neuroprotective purpose, since it will be employed to reduce early and late damage to neuronal cells following tissue damage related to neurodegenerative diseases of retina and optic nerve. The selected growth factors present in blood serum - especially in cord blood serum- have a strong neurotrophic effect supporting growth and survival of neuronal cells and glia, therefore determining the neuroprotective effect of the eye-drop to be developed.

The product to be developed could be used in the treatment of neurodegenerative diseases of the retina and optic nerve.

Page published on: 08 August 2018