67057 - Metabolism and Toxicology of Pollutants

Academic Year 2017/2018

  • Docente: Giorgio Sartor
  • Credits: 6
  • SSD: BIO/10
  • Language: Italian
  • Teaching Mode: Traditional lectures
  • Campus: Bologna
  • Corso: First cycle degree programme (L) in Chemistry and Materials Chemistry (cod. 8006)

Learning outcomes

At the end of the course students will achieve knowledge on the interaction between xenobiotic chemicals (benzene and its derivatives, aromatic compounds, organo-chlorinated and organo-phosphorous compounds and heavy metals) with environment and living organisms. Students will achieve also knowledge on toxicity due to reactive oxygen specie.

Course contents

Xenobiotics and pollutants;
Interaction between xenobiotics and organisms
Reactive Oxygen  and Nitrogen Specie
Metabolism of xenobiotics
Phase I enzymes (Cyt P450)
Phase II enzymes
Degradation pathways of aromatic compounds

Degradation of organochlorine derivatives and of organophosphorus derivatives.
Biotrasformation of metals.

Readings/Bibliography

Teaching notes available on-line

Teaching methods

Frontal lesson

Assessment methods

Power point presentation (10 slides max) followed by a discussion.

Links to further information

http://www.gsartor.org/pro/index.html

Office hours

See the website of Giorgio Sartor