The invention concerns the trans-species oral transplantation of the intestinal microbiota from a healthy monogastric herbivore to an omnivore affected by dysbiotic disorders
| Patent title | Trapianto trans-specie di microbiota intestinale |
|---|---|
| Thematic area | Bioeconomy, Agriculture and Environment |
| Ownership | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA |
| Inventors | Rossella Terragni, Silvia Turroni, Marco Candela, Simone Rampelli |
| Protection | IItaly, with the possibility to extend internationally |
| Licensing status | Available for development agreements, option, license and other exploitation agreements |
| Keywords | Pet health, Intestinal infections, microbiome transplantation, treatment od dysbiotic diseases |
| Filed on | 24 February 2022 |
Intestinal dysbiosis is typically treated with antibiotics, in combination with diet, prebiotics and pro-biotics.
However, the antibiotic acts locally, but it has a transient efficacy and frequently induces long-term antibiotic-resistance, with a consequent high risk of reappearance of the disease and associated dysbiosis. There is therefore a need for a new therapeutic approach for the treatment of dysbiosis pathologies that does not present the aforementioned disadvantages.
The invention relates to a new intestinal microbiota transplantation process for the treatment of acute and chronic inflammatory intestinal diseases in omnivorous animals belonging to the class of mammals. In particular, the process involves the transplantation of trans-species intestinal microbiota from a monogastric herbivore donor to an omnivore recipient through a controlled process of oral administration. The process is functional to the treatment of pathologies of the gastrointestinal tract of the omnivore recipient.
Applications:
• Treatment of chronic intestinal diseases
Advantages:
• Ease of administration
• Effective treatment
• Decrease in use of antibiotics