Chemical and Genomic-based startegies in the discovery of novel drug targets

Year 2020
Code 5584
Main Department Dipartimento di Farmacia e Biotecnologie - FaBiT
Campus Bologna
Credits 3
Cost € 100,00
Application deadline Jul 10, 2020 (Expired)
Subject area
Sciences and technology
Learning outcomes
In the last decade we have witnessed changes in the design and conduction of research in the biomedical field, resulting from the decoding of the human genome. In particular , it is relevant that the revolution has been focused on the discovery of new drugs and new drug targets thanks to genomics, transcriptomics and proteomics. The selection and validation of new drug targets requires a number of research strategies that have been developed recently. The aim of the School is to spread among young people in education and among those who are already working in this field, how to best use the tools offered by the most advanced research and updated . Experts, leaders in their field, were invited as lecturers. They will explain, through lectures and a lab exercise, the following topics: chemogeomics, drug discovery, genomics; the role of high-throughput assays; the small interfering RNA; reporter gene models in vitro and in vivo; transcription factors as new therapeutic targets; chemiluminescence Integrated systems for analysis. Finally, we will sketch the lines of the future development of these technologies. In order to better facilitate the dialogue between teachers and students, there are two moments in the middle and at the end of the course, in which students will be encouraged to ask teachers questions on the topics that most interested them. Further information on the objectives, professional context and teaching programme can be found in the Programme presentation sheet published on the website: http://www.unibo.it/Portale/Offerta+formativa/Summer+and+winter+school/default.htm
Number of participants
Min 8 - Max 50
Duration
5 days
Language
English
Admission qualifications
a) First cycle degree/Bachelor - 180 ECTS (General policies and regulations D.M. 270) in the following course classes: L-2 Biotechnologies, L-13 Biology, L-29 Pharmacy or First cycle degree/Bachelor of the same subject area, (General policies and regulations DM 509/99 and previous degree programme system);
b) Second cycle degree/Two year Master - 120 ECTS (General policies and regulations D.M. 270) in the following course classes: LM-6 Biology, LM-8 Industrial Biotechnologies, LM-9 Pharmaceutical, Veterinary and Medical biotechnologies, LM-13 Pharmacy and industrial pharmacy, LM-41 Medicine, LM-54 Chemistry or Second cycle degree/Two year Master of the same subject area, (General policies and regulations DM 509/99 and previous degree programme system).
Other degrees are also accepted, provided they are supported by qualified and documented professional experience or additional documented post-graduate training in the subjects covered by the programme.

Students enrolled in the 4th or 5th years of LM-13 and Ph.D. students in biomedical fields.
Academic director
Santi Mario Spampinato
Study plan
  • Genetic and epigenetic pathways in drug discovery: Nuclear receptors as pharmacologicaltargets; SSD BIO/10 - PROF. Maurizio Crestani
  • Intellectual property and biotechnological innovation; SSD IUS/04; prof.Giorgio Spedicato
  • Laboratory Experience - SSD BIO/14; prof.Andrea Bedini
  • Biased agonism at GPCRs as a novel avenue for more effective and safer drugs: the paradigm of
    opioid receptors - SSD

 

  • Networks and drug discovery – Chim-08 - prof.  Maurizio Recanatini
  •  Pharmacological strategies against SARS-CoV-2-Med-17  -prof.  Stefano Rusconi 
  • Strategies to unravel, validate and confirm a novel mitochondrial regulator BIO-10 - prof.Nico Mitro 
  • On predicting Central Nervous System (CNS) drug distribution and effects with special emphasis on the physiologically-based approaches - prof. Liesbeth de Lange 
  • Covalent inhibitors of protein-protein interactions targeting Lys, Tyr, or His residues - prof. Maurizio Pellecchia 

Dott. Gabriele Campana

FaBiT

Via Irnerio 48, 40126 - Bologna  

gabriele.campana@unibo.it

Telephone

+39 051 2091852

Notices

le lezioni verranno erogate attraverso la piattaforma on line " Teams"

lessons delivered through the online platform "TEAMS"