Chemical and genomics-based strategies in the discovery of novel drug targets - cod. 5584 (2019)

Year 2019
Code 5584
Main Department Dipartimento di Farmacia e Biotecnologie - FaBiT
Campus Bologna
Credits 3
Cost 100 euros
Starting date Jun 24, 2019
Finishing date Jun 28, 2019
Application deadline Jun 15, 2019 (Expired)
Subject area
Health
Learning outcomes
In the last decade we have witnessed changes in the design and conduction of research in the biomedical field, resulting from the decoding of the human genome. In particular , it is relevant that the revolution has been focused on the discovery of new drugs and new drug targets thanks to genomics, transcriptomics and proteomics. The selection and validation of new drug targets requires a number of research strategies that have been developed recently. The aim of the School is to spread among young people in education and among those who are already working in this field, how to best use the tools offered by the most advanced research and updated . Experts, leaders in their field, were invited as lecturers. They will explain, through lectures and a lab exercise, the following topics: chemogeomics, drug discovery, genomics; the role of high-throughput assays; the small interfering RNA; reporter gene models in vitro and in vivo; transcription factors as new therapeutic targets; chemiluminescence Integrated systems for analysis. Finally, we will sketch the lines of the future development of these technologies. In order to better facilitate the dialogue between teachers and students, there are two moments in the middle and at the end of the course, in which students will be encouraged to ask teachers questions on the topics that most interested them. Another highlight will be the individual experience in the laboratory, where each student will engage in experiments planned under the guidance of specialized tutors.
Number of participants
Min 8 - Max 50
Duration
5 days
Language
English
Admission qualifications
First cycle degree/Bachelor - 180 ECTS (General policies and regulations D.M. 270) in the following course classes: L-2 Biotechnologies; L-29-Pharmacy; L-13-Biology or First cycle degree/Bachelor of the same subject area, (General policies and regulations DM 509/99 and previous degree programme system).

Second cycle degree/Two year Master - 120 ECTS (General policies and regulations D.M. 270) in the following course classes: LM-13 - Pharmacy and industrial pharmacy; LM-9- Pharmaceutical, Veterinary and Medical biotechnologies; LM-8 - Industrial Biotechnologies; LM-41-Medicine; LM-54-Chemistry; LM-6-Biology or Second cycle degree/Two year Master of the same subject area, (General policies and regulations DM 509/99 and previous degree programme system).

Are also accepted students enrolled to the 4th or 5th year of LM 13 or other Pharmacy courses
Academic director
Santi Mario Spampinato
Place of teaching
FaBiT Department, Via Irnerio 48 - Bologna
Study plan
  • Genetic and epigenetic pathways in drug discovery: Nuclear receptors as pharmacological targets - BIO/10 - Prof. Maurizio Crestani
  • Intellectual property and biotechnological innovation - IUS/04 - Prof. Giorgio Spedicato
  • Laboratory - Practical experience - Bio/14 - Prof. Andrea Bedini
  • Biased agonism at GPCRs as a novel avenue for more effective and safer drugs: the paradigm of opioid receptors   Bio/14 - Prof. Andrea Bedini                              
  • Bioinformatics - BIO/10 - Pier Luigi Martelli
Compulsory attendance
80%
Final Examination
yes