PhD in Cardio Nephro Thoracic Sciences

1. Cardiology/Cardiac Surgery
2. Nephrology/Urology
3. Pulmonary Diseases/Thoracic Surgery

Curriculum 1: Cardiology/Cardiac Surgery

• Pulmonary Hypertension: Pharmacotherapy of induction
• New perspectives in the treatment of acute and chronic ischemic heart disease
• New approaches to percutaneous treatment of aortic and mitral valve disease
• Personalized therapy, “genetic driven”, of cardiomyopathies
• New techniques of catheter ablation for the treatment of arrhythmias
• Brain protection in aortic arch surgery. Myocardial protection in cardiac surgery
• Heart transplantation. Aortic valve replacement with prosthesis “sutereless”
• “Frozen elephant trunk technique” surgery for extensive diseases of the thoracic aorta
• Decellularized scaffolds in pediatric cardiac surgery.

Curriculum 2: Nephrology/Urology

• Imaging in the diagnosis, staging and restaging of prostate cancer evaluation of the role of new radiotracers for PET and identify the presence of lymph node metastases using the histological gold standard diagnostic
• to determine the role of PET in restaging of patients with recurrent disease and assess the main clinical indicators may be related to a positive imaging
• to evaluate the multiparametric MR in the local staging of disease prior to surgery and in patients in active surveillance for prostate cancer indolent
• Laparoscopy in urology oncology
• Application of laser technology for the treatment of benign prostatic hypertrophy (HoLEP)
• retrograde treatment of kidney stones through the use of flexible instruments (RIRS, retrograde intrarenalsurgery) and the technique combined antegrade-retrograde (ECIRS (endoscopiccombinedintrarenalsurgery)

Curriculum 3: Pulmonary Diseases/Thoracic Surgery

• Technological innovations innthe treatment of acute and cronic respuratory failure
• Physiopathological mechanisms of exacerbation of chronic respiratory disorders
• Home monitoring for chronic respiratory patients
• Prevention of the respiratory infections in critically ill patients
• Surgical therapy of experimental model of pulmonary hypertension
• Pathogenetic factors of fibrosis in the esophageal gastro-esophageal reflux disease
• Biomolecular characterisctics of pathogenesis of esophageal adenocarcinoma
• The neuroendocrine tumors of the chest: from neuroepithelial bodies & Co. to disease
• The role of the genetic and biomolecolar markers for a multidsciplinary tailored therapy
• The minimally-invasive diagnostic and therapeutic approach to lung cancer: between present time and future perspectives
• Study of pulmonary regeneration after pneumonectomy: experimental models and  their applications
• Enhancing lung transplantation: ex-vivo lung perfusion and other techniques.

NRRP Call - Further PhD Positions
Appointed by RD 952/2022 Prot. n. 0357333 of 02/12/2022

Call for Application and NRRP Call
Appointed by RD 830/2022 Prot. n. 0127511 of 30/05/2022
Confirmed by RD 1103/2022 Prot. n. 0162873 of 17/07/2022

The PhD program is dedicated to Cardiology / Cardiac Surgery, Nephrology/ Urology, Pulmonology/Thoracic surgery/ Esophageal surgery .It is articulated in basic and clinical research in the fields of stem cells, genetics, thoracic oncology , immunology, in any area of possible development of research pertinent to the curricula in which the course of doctorate is organized. The educational objectives are:

• the introduction to the methodology of scientific research
• the acquisition of bibliographic research methodologies , implementation of the data base, statistical processing data
• the acquisition of special laboratory techniques in the context of defined research projects
• the acquisition of modern computer aids for research and communication
• knowledge of the basic rules of medical ethics in clinical research and the ethics of laboratory experimentation
• knowledge of methods of structure of research protocols.

Students will play the research activity understood as "learning laboratory." Common to all the addresses are the bibliographical research, understanding and review of the literature, preparation of study protocols, statistical analysis of the data collected for preparation of abstracts, communications, articles, preferably to be submitted to Congress and international journals whose access is tramita "peer review". Students will be primarily responsible for the process of "peer review" process, the presentation and discussion of the data at conferences. Students who have chosen to address the basic research laboratory activities take place, other laboratory and clinical or clinical only. The experimental samples will be in the various options experiments and patients.

The training consists of research laboratory and / or clinical research, coordinated by the Superivsore Ph.D., and educational activities, including four areas of training: Common University, common doctorates medical area, common and specific PhD.

The University organizes the basic training on the management of research, knowledge of research systems and financing systems, exploiting the results of research and intellectual property, business culture. PhD students with specific interests can also follow advanced courses on these topics.

The Doctoral medical area organize courses of scientific English (24 hours, in collaboration with the University Language Centre) and safety courses in biomedical environment (12 hours, in collaboration with the Area People and Organisation of the University and with Referrals to the Security Departments of reference).

The PhD organizes seminars common members of the Academic Board. The main topics are those described in reference to the three curricula which make up the PhD program.

The Supervisor directs the PhD student to specific training events (conferences, workshops, internships, revisions of case studies, etc.) And is responsible for computer training advanced according to the research project.

The PhD program has established a cooperative relationship with universities and scientific training centers and multinational companies with intensive research and development in the biomedical field, in Europe and North America.

Curriculum: Cardiology / Cardiac Surgery

• University Hospital St. Luc Universitè Catholique de Louvain Brüssel Belgium
• Utrecht University Hospital Heart Lung Institute Utrecht Netherlands.

Curriculum: Nefrology-Urology

• Nephrology Service, Hospital Universitari Bellvitge, Universität de Barcelona
• Fresenius Medical Care International - Bad Homburg Germany
• Novartis

Curriculum: Pneumology-Thoracic surgery

• University of Toronto, Division of Thoracic Surgery Toronto General Hospital, Canada
• Columbia University Medical Centre, NY
• -Presbyterian Hospital, NY, USA
• Silicon Byosistems
• University Hospital Zurich
• Dept. of Thoracic surgery - Switzerland
• Vienna Medical University
• Dept. of Thoracic surgery - Austria
• Universitair Ziekenhuis Leuven
• Dept of Thoracic Surgery Belgium
• King’s College London, UK
• Tuffs University, Boston, MA, USA
• University Ghent, Gent, Belgium
• European Health Center - Otwock, ECZ-Otwock, Poland

Products and expected results of the research activities of graduate students (preferably on the basis of quantitative criteria and / or time, such as books, publications and necklaces in magazines, patents, software, postgraduate papers in national and international conferences, etc.