- Docente: Giulio Agnetti
- Credits: 9
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 8415)
Learning outcomes
The main objective of this course is to provide knowledge on the following subjects: general characteristics of chemical reactions (stoichiometry, kinetics and spontaneous reactions); properties of the chemical components in living organisms: structure and properties of simple and complex carbohydrates and lipids; thermodynamic aspects of biochemical processes and cellular bioenergetics; structural and functional properties of proteins; enzyme mechanism of action and kinetics; regulation of biochemical reactions rate;
structure of nucleic acids and the description of the mechanisms involved in DNA replication, transcription and translation (protein synthesis).
Course contents
Amino acids and their properties. Protein structure and conformation. Denaturation.
Hemoglobin: structure, oxygen binding, regulation. Hemoglobinopathies.
Enzymes. Kinetics of enzymatic reactions. Mechanism of action of the enzymes and their allosteric, covalent, genetic regulation.
Readings/Bibliography
Lehninger Principles of Biochemistry - David L Nelson, Michael M Cox
Marks Basic Medical Biochemistry - Michael Lieberman, Allan Marks
Teaching methods
Lectures
Assessment methods
Multiple choice test
Teaching tools
Powerpoint slides
Office hours
See the website of Giulio Agnetti