00064 - General Biochemistry

Academic Year 2022/2023

Course contents

MODULO for Orthopedic techniques and Dietistic


  • The chemical foundations of biochemistry. Water and pH.
  • Amino acids, peptides and proteins.  
  • Enzymes and their regulation. Coenzymes and vitamines.
  • Bioenergetics and role of ATP. Catabolism and anabolism.
  • Structure and metabolism of carbohydrates. Digestion of carbohydrates. Blood glucose and its regulation. Overview of carbohydrate metabolism. Glycogen synthesis and glycogenolysis. Glycolysis and glucogenesis. Pentose phosphate cycle.
  • Pyruvate oxidation and citric acid cycle (TCA cycle). Respiratory chain and oxidative phosphorylation.
  • Structure of lipids. Overview of lipid metabolism. Digestion of lipids. Plasma Lipoproteins. Lipolysis and lipogenesis. beta-oxidation of fatty acids. Ketone bodies. Cholesterol.
  • Metabolism of nitrogen compouds. Digestion of proteins. Overview of amino acid metabolism. Fate of carbon skeleton and amino group of aminoacids. Urea cycle. Gluconeogenesis. Biogenic amines.
  • Signal transduction Nuclear and membrane receptors. Main hormones regulating metabolism: glucagon, insulin, catecholamines, glucocorticoids.
  • Metabolic interelations among tissues. Biochemistry of bone and cartilage. Collagen, glycosaminoglycans. Regulation of blood calcium.


MODULO 2 (only for Dietistic)


Office hours

See the website of Flavio Flamigni

See the website of Silvia Cetrullo